Typing tool
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Typing tool
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Complete norovirus genomes
| MK753035 | GII.2 | |
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| GII.P16 |
ORF1: 3..5102
ORF2: 5083..6711
ORF3: 6711..7490
LOCUS MK753035 7530 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P16-GII.2/Washington0353
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK753035
VERSION MK753035.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7530)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7530)
AUTHORS Barclay,L., Cannon,J.L., Pan,C.-Y., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7530
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Washington0353"
/isolate="Hu/US/2016/GII.P16-GII.2/Washington0353"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="31-Aug-2016"
/note="genotype: GII.P16-GII.2"
gene 3..5102
/gene="ORF1"
CDS 3..5102
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS54675.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGVSGLPELTTVPQ
PDVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
VSMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEV
EKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVK
TMEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEE
APKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPAGITEAFGVPIKQIQIHKSGEFCRFRFPKPIRSDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMRIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVVGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPYHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIVQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 3..998
/gene="ORF1"
/product="p48"
mat_peptide 999..2096
/gene="ORF1"
/product="NTPase"
mat_peptide 2097..2627
/gene="ORF1"
/product="p22"
mat_peptide 2628..3026
/gene="ORF1"
/product="VPg"
mat_peptide 3027..3569
/gene="ORF1"
/product="Pro"
mat_peptide 3570..5099
/gene="ORF1"
/product="RdRp"
gene 5083..6711
/gene="ORF2"
CDS 5083..6711
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS54676.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLSLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNITITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6711..7490
/gene="ORF3"
CDS 6711..7490
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS54677.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTVSSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMRGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 gaatgaagat ggcgtctaac gacgctaccg ttgccgttgc ttgcaacaac aacaacgaca
61 aagaaaaatc ttcaggtgaa ggcttattca caaatatgtc ttccacctta aagaaagccc
121 tcggggctag gcccaaacag cctgccccga gagacaaacc acaaaagccc ccaagaccac
181 caactcccga gttggtcaag aggatacccc ctcctccacc taatggcgaa gaagaagaag
241 aaccagtcat taggtatgag gttaagagtg gggtctctgg cctgcccgag ctcacaacag
301 tcccccaacc ggacgtggcc aacacagcat tcagtgttcc accactgagc ttgagagaaa
361 acagggaggc caaggaaccg ctaacagggg caatattaga gatgtgggat ggagagatat
421 accactatgg cctgtacgtg gagaaaggct tagtgttggg tgtgcacaaa ccacctgcag
481 ccgtaagcat ggcaagagtg gagctgacgc cgctgtcatt gtactggcgt gtggtgtaca
541 ctccccaata cctcatctcc cctgaaaccc tcaggagact caacggagag gcgttccctt
601 acaccgcctt tgacaataac tgctatgcct tttgctgctg ggtgttagac ctcaatgact
661 catggcttag caggaggatg gtgcaaagaa caacgggctt ctttagacct taccaagagt
721 ggaacagaaa acccctgccc accatggatg actccaaaat taagaaggta gcaaatatat
781 tcctatgctc attgtccaca ttattcacca gacccataaa agacctcata ggaaaaatta
841 aaccattaaa catattgaat atcctggcaa cgtgtgactg gacttttgcc ggaatagtgg
901 agtctctgat attacttgct gaactcttcg gagttttctg gacaccccca gatgtgtctg
961 ctatgatcgc tcccttactc ggggactacg agttgcaggg gccagaagac ctcgccgttg
1021 aactcgtacc cgtggtaatg ggggggattg gtttggtgtt gggattcacc aaagagaaaa
1081 ttggcaaaat gttgtcctca gcagcatcaa cactcagggc ttgcaaagat cttggtgcct
1141 atggcttaga gatactcaaa ttggtcatga agtggttctt cccaaagaaa gaggaggcca
1201 atgagctagc catggtgagg gccatagagg atgctgtact agatcttgag gcaatagaaa
1261 ataaccacat gacaaccctg ttaaaagaca aagacagctt agcaacatac atgaaaacac
1321 tggacatgga ggaggagaaa gccaggaggt tgtccacaaa atctgcatcc cctgacatag
1381 ttgggacaat caacgccctg ctggctcgaa tagcagcggc caggtcatta gtccacaggg
1441 ccaaggaaga gctatctagc aggataagac cagtagttgt tatgatatct ggcaaaccag
1501 gaataggcaa aactcatctg gccagggagg tggcaagaaa ggtggcatcc actctcacag
1561 gggatcagag agtcggactc ataccaagaa acggtgtgga ccattgggat gcatacaaag
1621 gtgagagagt cgtgctgtgg gacgactatg gcatgagtaa ccccattcat gatgctcttc
1681 gcatacaaga attggctgat acgtgtcccc ttaccttaaa ttgtgacaga attgaaaata
1741 agggaaaagt ttttgacagc gaggtcataa taattacaac aaaccttgcc aatccagccc
1801 cacttgatta tgttaacttt gaggcctgtt ccaggagaat tgatttcctg gtgtacgctg
1861 aggcaccaga agtagaaaag gcaaaacggg actttcctgg tcagccagat atgtggaagg
1921 atgccttcaa gcccgacttt tcacacatca agctacagct tgcaccccag ggcggctttg
1981 acaagaatgg caacacccca catgggaaag gagtgatgaa gaccctcact accggttctc
2041 tgattgcccg cgcatcaggc ctactgcatg agaggatgga tgaatttgaa ctccaaggtc
2101 ccacaatcac caccttcaat ttcgaccgga acagaatcac agcattcaga caattggctg
2161 cagaaaacaa gtatggattg gtggatacca tgaaagttgg caatcaacta aaaggagtga
2221 aaaccatgga ggaacttaaa caagcaatca ggaatgtgac catcaagagg tgccggatca
2281 tctacggtgg ctccacgtat gaccttgaat ctgatggcaa gggcaaagtt ttggtggaaa
2341 aggtcaagaa cacctctgta cagaccaaca acgagttggc tggggccctg caccatctca
2401 aacacgcccg aatcaggtac tatgtcaaat gtgtgcaaga agcagtctat tccatcatac
2461 aaattgccgg cgctgcgttt gtcaccacgc gcattgcacg ccgcatgaac atacaagaac
2521 tctggtcgaa gccacaatta gatcaaaatg aatcagagac taaggaagag gcccccaagt
2581 cagaagatga cgagttcatc atatcttcta aggacatcaa ggaggaagga aagaagggta
2641 aaaacaaaac tggccgtggc aagaaacaca ctgcattctc cagcaagggc ttgagcgatg
2701 aggagtatga cgagtacaag aggataagag aagagaggaa tgggaagtac tccatagagg
2761 agtatcttca agacagagac aggtactatg aggagctcgc cattgccaag gccacggaag
2821 aagacttctg tgaagaagag gagatcaaaa tccgtcagag aattttccgt cccaccagga
2881 aacaaagaaa ggaagagagg gccacattag ggctagtaac aggttcagaa atcagaaaaa
2941 gaaaccctga tgacttcaaa cccaaaggga agctgtgggc cgatgacaac aggagtgttg
3001 actacaatga gaaactggac tttgaggccc ccccaagcat atggtctagg attgtgagct
3061 ttggttctgg ctggggcttc tgggtgtcac caagcctttt cataacatca actcatgtaa
3121 tccccgcagg cataacagaa gcatttggag tccccatcaa acaaattcag atccacaaat
3181 caggtgaatt ttgccgattc agattcccaa aaccaattag atcagatgta acagggatga
3241 tcttggaaga aggtgcgcct gagggcaccg tggcaactgt gctcatcaaa cgccccaccg
3301 gggagctcat gcctcttgca gccagaatgg gaacacacgc aaccatgaga attcaaggcc
3361 gcatggttgg cggacagatg ggtatgttgc tcactggatc aaatgctaaa ggaatggatt
3421 tgggaacaac tcctggtgac tgtggctgcc cttacatcta taaaagaggc aatgactata
3481 tagtcgttgg ggtgcacact gcagcagccc gtggtggaaa caccgtcatc tgtgccacac
3541 agggaagtga gggtgaggca actcttgagg gtggagatga caaaggaaca tactgtgggg
3601 cacccattct aggccctggg ggtgcaccaa aattgagcac caaaaccaaa ttttggaggt
3661 catcgaacac gccccttcca ccagggacat atgagcctgc ctacctcggt ggccgtgatc
3721 cgcgtgttaa gggtgggccc tccctgcagc aggtaatgag agaccagttg aagccattca
3781 ctgaacccag gggcaaacct ccaagaccaa gtgtattgga agcagccaaa caaaccatca
3841 tcaatgtcct cgaacaaacc ctggaccctc cacaaaaatg gacatacgca caggcgtgtg
3901 cctcacttga caaaaccacc tccagcgggc atccctatca cgtccgaaag aatgaattct
3961 ggaatggtga gacgttcact ggaaaattgg cagaccaagc atcaaaagca aacctaatgt
4021 ttgaggaagg gaaacacatg acaccagtgt acacagcagc actcaaggac gagctagtca
4081 agactgagaa aatctatgga aagatcaaga agagactgct ctggggctct gacttgtcca
4141 ctatgatccg gtgcgctagg tcatttggtg ggctcatgga cgagatgaag gcacactgca
4201 tatcactccc agtccgagtt ggcatgaaca tgaatgaaga tggcccaata atatttgaga
4261 aacattccag atacaaatac cactatgatg cagactactc tcgttgggat tcaacacaac
4321 agagggcagt actagcagca gccttggaaa ttatggtcag attctctgca gaaccacaat
4381 tggcacaaat agtcgctgag gatctgctgg cccctagtgt agtagatgtg ggagacttta
4441 aaattacaat aaatgaaggg ctcccctctg gtgtgccatg cacttctcaa tggaactcca
4501 tcgcacactg gctgctaact ctctgtgcct tgtctgaagt caccaaactg tcccctgaca
4561 ttgtacaggc aaattccatg ttctcatttt acggtgatga cgagattgtc agcaccgaca
4621 taaaattgga ccctgaacag ttaaccgcca aattgaaaga gtacggcctg aaaccaaccc
4681 gcccagacaa aaccgaggga cccctgatta tcagtgaaga tttgaacgga cttactttcc
4741 tccgaaggac ggtgactcgt gacccagctg gttggtttgg aaaattggac caaagctcaa
4801 ttttgaggca gatgtactgg actagaggac caaatcatga agaccccaat gagacaatga
4861 taccccattc tcaaagaccc atacagctca tggcactgct tggtgaagcc tctcttcacg
4921 gaccctcttt ctacagtaaa attagtaaat tggtcataac tgaactcaaa gaaggtggga
4981 tggactttta cgtgccaagg caggaaccca tgttcaggtg gatgaggttt tctgacttga
5041 gcacgtggga gggcgatcgc aatctggctc ccaattttgt gaatgaagat ggcgtcgaat
5101 gacgccgctc catctactga tggtgcagcc ggcctcgtgc cagaaagtaa caatgaggtc
5161 atggctcttg aacccgtggc tggtgccgcc ttggcagccc cggtcactgg tcaaacaaat
5221 attatagacc cttggattag agcaaatttt gtccaggccc ccaatggtga atttacagtc
5281 tctccccgta atgcccctgg tgaagtgtta ctgagtctag agttgggtcc agaattaaat
5341 ccttatctgg cacatttagc aagaatgtac aatgggtatg ccggtgggat ggaggtgcag
5401 gtcatgttgg ctgggaacgc gttcacagcc ggcaagttgg tcttcgccgc cgtgccacct
5461 cacttcccgg ttgaaaacct tagcccacag caaatcacca tgttccctca tgtgatcata
5521 gatgtgagaa ccttggaacc tgttttatta ccactccctg atgttagaaa taatttcttc
5581 cattataatc agaaagatga tcccaagatg agaattgtgg ctatgcttta tacccccctc
5641 aggtctaatg gttcaggtga tgacgtgttt acagtctcct gcagagtgtt gactagacct
5701 tcccctgact ttgacttcac atacctggtg ccaccaacag tggagtctaa aacaaaacca
5761 ttcaccctcc caatcctcac acttggggaa ctttccaatt ccaggttccc agtgtccata
5821 gaccagatgt ataccagccc taatgaagtt atatcagtgc agtgtcaaaa tggtaggtgc
5881 acactggacg gggagctcca ggggacaaca caactccaag tcagtggcat ttgtgctttc
5941 aaaggtgaag tgaccgccca cttgcatgac aatgatcacc tatataatat taccatcaca
6001 aacttgaatg ggtccccttt tgatccctcc gaggatatcc ctgcccctct gggtgtgcct
6061 gacttccagg gaagggtttt tggtatcatc tcccaaagag acaaacacaa tagtcctggg
6121 cataatgaac cagcaaacag gggacacgac gctgtggttc ccacttacac agcacagtac
6181 actccaaaac tgggacaaat tcaaattggc acatggcaga ctgacgatct tacagtcaac
6241 caaccagtca aattcacccc agttggactc aatgacactg aacatttcaa ccaatgggtg
6301 gtccctaggt atgctggtgc cctaaacctc aatacaaacc ttgccccttc tgttgctcca
6361 gtatttccag gagagcgtct gctcttcttc agatcataca ttcccctcaa gggcggttat
6421 ggaaacccag ccattgattg cctactacca caagagtggg tgcaacactt ctatcaggaa
6481 gcagcccctt caatgagtga ggtggccctc gtcagataca tcaacccgga cactggtcgg
6541 gcactgtttg aggccaagct ccacagagct ggtttcatga cagtctcgag caacaccagt
6601 gccccggtgg ttgtgcctgc caacggatac ttcagatttg attcttgggt gaaccaattc
6661 tattctctcg cccccatggg aactgggaat gggcgtagaa gggttcaata atggctggag
6721 cttttgtagc tggtcttgca ggggatgtgc tcagcaatgg gcttagttca ttaatcaatg
6781 caggtgctaa tgcaataaat cagagggcag aatttgattt taatcagaaa ttgcagcaaa
6841 attcttttaa tcatgataag gagatgttgc aggctcagat tcaggcaact aagcagctgc
6901 aggcagacat gatggctata aaacaagggg tcttgaccgc tggcggcttt tcccctgctg
6961 atgcagccag aggtgctgtg aacgcgccca tgacacaagc gctggattgg aatggtacaa
7021 ggtattgggc accaaactcc atgaggacca catcttattc tggaaaattc acatcaaccg
7081 ccccagtgag gcaggccgac ttccagcaca cccaaagccg gccttcgagt ggctcctctg
7141 tgtcttcctt tgccactcag tcttcaaggc caactctgac cacaaccact ggttcctcac
7201 atggcacagt ctcatcaaat tcaactcgca gcacaagcct ctcccaatca acggtctcca
7261 gagccacatc taggactggt gagtgggtta gagatcaaaa tagaaatttg gaaccctaca
7321 tgcgtggtgc cttacagaca gcctttgtca ccccaccttc cagcagggca tctgacggga
7381 cagtctcaac cgtcccgaaa ggtgttttgg actcctggac acctgcgttt aacacccgca
7441 ggcagccgct ttttgcacac ctccgtaaga ggggggagtc acaagcttag tgaaaaggtg
7501 aaaatttatt taggatgaat tgaatttacc
//