Typing tool
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Typing tool
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Complete norovirus genomes
| MK753034 | GII.1 | |
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| GII.P16 |
ORF1: 5..5104
ORF2: 5085..6692
ORF3: 6692..7465
LOCUS MK753034 7494 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P16-GII.1/SaltLake0124
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK753034
VERSION MK753034.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7494)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7494)
AUTHORS Barclay,L., Cannon,J.L., Pan,C.-Y., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7494
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="SaltLake0124"
/isolate="Hu/US/2017/GII.P16-GII.1/SaltLake0124"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="18-Jun-2017"
/note="genotype: GII.P16-GII.1"
gene 5..5104
/gene="ORF1"
CDS 5..5104
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS54672.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDEPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQ
PGVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
ISMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILLAELFGLFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRMRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEV
EKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVK
TMEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEE
APKPEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPAGITEAFGVPIKQVQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 5..1000
/gene="ORF1"
/product="p48"
mat_peptide 1001..2098
/gene="ORF1"
/product="NTPase"
mat_peptide 2099..2629
/gene="ORF1"
/product="p22"
mat_peptide 2630..3028
/gene="ORF1"
/product="VPg"
mat_peptide 3029..3571
/gene="ORF1"
/product="Pro"
mat_peptide 3572..5101
/gene="ORF1"
/product="RdRp"
gene 5085..6692
/gene="ORF2"
CDS 5085..6692
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS54673.1"
/translation="MKMASNDAAPSNDGAAGLVPEVNNETMALEPVAGASIAAPLTGQ
NNVIDPWIRMNFVQAPNGEFTVSPRNSPGEVLLNLELGPELNPFLAHLSRMYNGYAGG
VDVQVLLAGNAFTAGKLVFAAIPPHFPLENLSPGQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQQPEPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFNYLVPP
TVESKTKPFTLPILTIGELSNSRFPVPIDELYTSPNEGVVVQPQNGRSTLDGELLGTT
QLVPSNICALRGRINAQVPDDHHQWNLQVTNANGTPFDPTEDVPAPLGTPDFLANIYG
VTSQRNPDNTCRAHDGVLATWSPKFTPKLGSVVLGTWEERDLDLNQPTRFTPVGLYDT
NHFDQWILPNYSGRLTLNMNLAPSVAPLFPGEQILFFRSHIPLKGGTSNGAIDCLLPQ
EWVQHFYQESAPSPTDVALIRYTNPDTGRVLFEAKLHRQGFITVANSGSRPIVVPPNG
YFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6692..7465
/gene="ORF3"
CDS 6692..7465
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS54674.1"
/translation="MAGAFVAGLAGDIVTNSIGSLVNAGANAINQKVDFENNKQLQQA
SFNHDKEMLQAQIQATKQLQADMVALRQGVLTAGGFSPTDAARGAVNAPMTQVLDWNG
TRYWAPGATKTTAFSGGFTSSPNTRTVDLPRKTSTTPAPTPISRSSSSASTVSTRSTI
VSGTSGLSSLTRSSFNSQPTSSSSRTSEWVRSQNRALEPYMRGALQTAYVTPPSSRAS
SNGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRRRGESHV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgctac cgttgccgtt gcttgcaaca acaacaacga
61 caaggaaaaa tcttcaggtg aaggcttatt cacaaatatg tcttccacct taaagaaagc
121 cctcggggct aggcccaaac agcctgcccc gagagacgaa ccacaaaagc ccccaagacc
181 accaactcca gagttggtca agaggatacc ccctcctcca cctaatggcg aggaagaaga
241 agaaccagtc attaggtatg aggttaagag tgggatctct ggcctgcccg agctcacaac
301 agtcccccaa ccgggcgtgg ccaacacagc attcagtgtt ccaccactga gcttgagaga
361 aaacagggag gccaaagaac cgctaacagg ggcaatatta gagatgtggg atggagagat
421 ataccactat ggcctgtacg tggagaaagg cttagtgttg ggtgtgcaca aaccacctgc
481 agctataagc atggcaagag tggagttgac gccgctgtca ttgtactggc gtgtggtgta
541 cactccccaa tacctcatct cccctgaaac tctcaggagg ctcaacggag aggcgttccc
601 ttacaccgcc tttgacaaca actgctatgc cttttgctgc tgggtgttag acctcaatga
661 ctcatggctt agcaggagga tggtgcaaag aacaacgggc ttcttcagac cttaccaaga
721 gtggaacaga aaaccccttc ctaccatgga tgactccaaa attaagaagg tagcaaatat
781 attcctatgt tcattgtcca cattattcac cagacccata aaagacctca taggaaagat
841 taaaccatta aacatattga acatcctggc aacgtgtgac tggacgtttg ccggaatagt
901 ggagtctctg atattacttg ctgaactctt cggacttttc tggacacccc cagatgtgtc
961 tgctatgatc gctcccttac tcggggacta cgaattgcaa gggccagaag acctcgccgt
1021 tgaactcgta cctgtggtaa tgggaggaat tggtttggtg ttgggattca ccaaagagaa
1081 aattggcaaa atgttgtcct cagcagcatc aacactcagg gcttgcaaag atcttggtgc
1141 ctatggctta gagatactca aattggtcat gaagtggttc ttcccaaaga aagaggaggc
1201 caatgagtta gccatggtga gggccataga ggatgccgta ctagatcttg aggcaataga
1261 aaataaccac atgacaaccc tgttgaaaga caaagacagc ttagcaacat acatgaaaac
1321 actggacatg gaggaggaga aagccagaag gctgtccaca aaatctgcat cccctgacat
1381 agttgggaca atcaacgccc tgctggctcg aatagcagcg gccaggtcat tagtccacag
1441 ggccaaggaa gagctgtcta gcaggatgag accagtagtt gttatgatat ctggcaaacc
1501 aggaataggc aaaactcatc tggccaggga ggtggcaaga aaggtggcat ccactctcac
1561 aggggatcaa agagtcggac tcataccaag aaacggtgtg gaccattggg atgcgtacaa
1621 aggtgagaga gtcgtgctgt gggacgacta tggcatgagc aaccccattc atgatgctct
1681 tcgcatacaa gaattggctg acacgtgtcc ccttacctta aattgtgaca gaattgaaaa
1741 taagggaaaa gtttttgaca gtgaggtcat aataatcaca acaaaccttg ccaatccagc
1801 cccacttgat tatgtcaact ttgaggcttg ttccaggaga attgattttc tggtgtacgc
1861 tgaggcacca gaagtagaaa aggcaaaacg ggactttcct ggtcagccag acatgtggaa
1921 ggacgccttc aagccggact tctcacacat caagctacag cttgcacctc agggcggctt
1981 tgacaagaat ggcaacaccc cacatgggaa gggagtgatg aagaccctca ctaccggttc
2041 tctgattgcc cgcgcatcag gcctactgca tgagaggatg gatgaatttg aactccaagg
2101 tcccacaatc accaccttca atttcgaccg taacagaatc acagcattca gacaattggc
2161 tgcggaaaac aagtatggat tggtggatac catgaaagtt ggcaatcaac taaaaggagt
2221 gaaaaccatg gaagaactca aacaagcaat caggaatgtt accatcaaga ggtgccggat
2281 catctacggt ggctccacgt atgaccttga atctgatggc aagggtaaag ttttggtgga
2341 aaaggtcaag aacacatctg tacagaccaa caacgagctg gctggggccc tgcaccatct
2401 caaacacgcc cgaatcaggt actatgtcaa atgtgtgcaa gaagcagtct attccatcat
2461 acaaattgcc ggcgctgcgt ttgtcaccac gcgcattgca cgccgcatga atatacaaga
2521 actctggtcg aagccacaat tagatcaaaa tgaatcagag actaaggagg aggcccccaa
2581 gccagaagat gacgagttca tcatatcctc taaggacatc aaggaggaag gaaagaaggg
2641 caaaaacaag actggccgtg gcaagaaaca cactgcattc tccagcaagg gcttgagcga
2701 tgaggagtat gacgagtaca agaggataag agaagagaga aatgggaagt actctataga
2761 ggagtatctt caagacagag acaggtacta tgaggagctc gccattgcca aggccacgga
2821 agaagacttc tgcgaagagg aggagatcaa aattcgtcag agaattttcc gtcccaccag
2881 gaagcaaaga aaggaagaga gggccacatt agggctagta acaggttcag aaatcagaaa
2941 aagaaaccct gatgacttca aacccaaagg gaagctgtgg gccgatgaca acagaagtgt
3001 tgactacaat gagaagctgg actttgaggc ccctccaagc atatggtcta ggattgtgag
3061 ctttggttct ggctggggct tctgggtgtc accaagtctg ttcataacat caactcatgt
3121 aatccccgca ggcataacag aagcgtttgg agtccccatc aaacaagttc agattcataa
3181 atcaggtgaa ttttgccgat tcagattccc aaaaccaatt agaccagatg tgacagggat
3241 gatcttagaa gagggtgcgc ctgaaggcac cgtagcaact gtgcttatca aacgccccac
3301 cggagagctt atgcctcttg cagccagaat gggaacacac gcaaccatga aaattcaggg
3361 tcgcatggtc ggcggacaga tgggtatgtt gctcactgga tcaaatgcta aaggaatgga
3421 tttgggaaca actcctggtg actgtggctg tccttacatc tataaaaggg gcaatgacta
3481 tatagtcatt ggggtgcaca ctgcagcagc ccgcggtgga aacactgtca tctgtgccac
3541 acagggaagt gagggtgagg caactcttga gggtggagat gacaaaggaa catactgtgg
3601 agcacctatt ctaggccctg ggggtgcacc aaagttgagc accaaaacca aattttggag
3661 gtcatcgaac acgccccttc caccagggac atatgaacct gcctacctcg gtggccgtga
3721 tccgcgtgtt aagggtgggc cctccttgca gcaggtaatg agagaccagt tgaagccatt
3781 cactgaaccc aggggcaagc ctccaagacc aagtgtattg gaagcagcca aacaaaccat
3841 catcaacgtc ctcgaacaaa ccctggaccc tccacaaaaa tggacatacg cacaggcgtg
3901 tgcatcactt gataaaacca cctccagcgg gcacccccat cacgtccgga agaatgaatt
3961 ctggaatggt gagaccttca ctggcaaatt ggcagaccaa gcatcaaaag caaacctaat
4021 gtttgaggaa gggaaacaca tgacaccagt gtatacagca gcactcaagg acgagctagt
4081 caagactgag aaaatctatg gaaagatcaa gaagagactg ctctggggct ctgacttgtc
4141 caccatgatc cggtgcgcta ggtcatttgg tgggctcatg gacgagatga aggcacactg
4201 catatcactc ccagtacgag ttggcatgaa tatgaatgaa gatggcccaa taatatttga
4261 gaaacattcc agatataaat atcactatga tgcagactac tctcgttggg attcaacaca
4321 acagagggca gtgctagcag cagccttgga aatcatggtc agattctctg cagaaccaca
4381 attggcacaa atagtcgctg aggatctgct ggcccctagt gtagtagatg tgggagactt
4441 taaaatcaca ataaatgaag ggctcccatc tggtgtgcca tgcacttctc aatggaactc
4501 catcgcacac tggctgctaa ctctctgtgc cttgtctgaa gtcaccaaac tatcccctga
4561 cattatacaa gcaaattcca tgttctcatt ttacggtgat gacgagattg tcagcaccga
4621 cataaaattg gaccctgaac agttaaccgc caaattgaag gagtacggcc tgaaaccaac
4681 tcgcccagac aagaccgagg gacccctgat tatcagtgaa gatttgaacg gactcacttt
4741 cctccggagg acggtgactc gtgacccagc tggctggttt ggaaaactgg accaaagctc
4801 aattttgagg cagatgtact ggactagagg accaaatcat gaagacccca atgagacaat
4861 gataccccat tctcaaagac ccatacagct catggcactg cttggtgaag cctctcttca
4921 cggaccctct ttctacagta aaatcagtaa attggttata actgaactca aagaaggtgg
4981 gatggacttt tacgtgccaa ggcaagaacc catgttcaga tggatgaggt tttctgactt
5041 gagcacgtgg gagggcgatc gcaatctggc tcccaatttt gtgaatgaag atggcgtcga
5101 atgacgccgc tccatctaat gatggtgcag ccggtctcgt accagaggtc aacaacgaga
5161 cgatggcact tgagccggtg gctggggctt ctatagctgc ccctttaacc ggccaaaata
5221 atgtgataga cccctggatt agaatgaatt ttgtccaagc tccaaatggt gaatttacag
5281 tgtccccccg taattcccca ggtgaagtgt tgttgaattt ggaattaggt cctgaactaa
5341 atccattcct ggcacacctt tcaagaatgt ataatggtta tgctggtggg gttgatgtgc
5401 aggtgctgct tgctgggaat gcgttcacag cgggaaaact agtgtttgca gcaatccccc
5461 cacatttccc tcttgagaat ttgagtcctg gtcaaattac aatgttccct catgtgatta
5521 ttgatgttag aactttagaa cctgtccttt tgcctttacc agatgttaga aataatttct
5581 ttcattacaa tcagcagcct gagccccgta tgagacttgt ggctatgttg tatactcctc
5641 tcagatctaa tggctctggt gatgatgtgt tcacagtctc ttgtagggtt ctcactcgcc
5701 cctctccaga ctttgatttc aattacttgg ttcccccaac tgtggaatct aaaaccaaac
5761 catttaccct gccaatattg accattggag aattgtcaaa ttctaggttc ccagtgccaa
5821 tagatgaatt gtatacaagc cctaatgaag gagtggttgt gcaacctcaa aatggcagat
5881 caacacttga tggtgaactg cttggcacca cacaacttgt accatcaaac atctgcgcct
5941 tgcgagggcg catcaacgcc caagtgccag acgaccacca tcaatggaac ttgcaggtta
6001 caaacgcaaa tgggaccccc ttcgacccca ctgaagatgt ccctgcacca ttgggcacgc
6061 cggatttctt ggcaaacatc tacggagtta ctagccagag gaatcctgac aacacttgcc
6121 gtgcccacga tggggtcttg gcaacctgga gccctaagtt cacacccaag ttaggctctg
6181 tggttttggg tacttgggaa gaacgtgatc ttgatctcaa tcaacctacc agattcacac
6241 ctgttggtct gtatgacaca aaccactttg atcagtggat tctacccaac tactctggaa
6301 gattgacctt aaacatgaat ttggcgccct ccgttgctcc ccttttccca ggtgaacaaa
6361 tactcttctt taggtcccac ataccactca aaggaggcac ttccaacggt gccattgact
6421 gtctactccc ccaggagtgg gtccagcatt tctatcagga atcagccccg tcacccacag
6481 atgttgctct gattaggtac accaaccctg acacgggccg tgtccttttt gaggccaaac
6541 tacatagaca gggattcatc acagtagcaa attctggttc tagacctatt gttgtccccc
6601 ctaatggtta ttttaggttt gattcttggg ttaatcagtt ttactctctc gcccccatgg
6661 gaactgggaa tgggcgtaga agagtgcagt aatggctgga gcttttgtag caggtcttgc
6721 cggtgatata gtcaccaata gcattggttc acttgtgaac gctggagcca atgcaataaa
6781 ccaaaaagta gattttgaaa acaacaaaca actacagcag gcctctttca accatgacaa
6841 ggaaatgttg caagctcaaa ttcaggccac aaaacaatta caggctgaca tggttgcgct
6901 cagacaaggg gtgttgaccg caggcggctt ctcccctact gatgcagcaa gaggggcggt
6961 taatgcgccc atgacgcaag tcttggactg gaatgggact aggtactggg cccccggagc
7021 caccaaaaca actgctttct ccggtgggtt cacaagctct cccaacacca ggactgttga
7081 tttgcctagg aaaacatcaa ctacaccagc ccccacacct atatctagat ctagttcttc
7141 tgcttctact gtttctaccc gctcaacaat tgtcagcggg acttctggcc tttcttcttt
7201 gactaggagc tcttttaatt cccagcccac ctcctcttct tctcggacta gcgagtgggt
7261 gcgtagtcaa aacagggcgc tggagcccta catgagggga gcactgcaaa ctgcttacgt
7321 gacgcctccc tctagtagag catccagcaa tggcacagtc tcaaccgtgc caaaagaagt
7381 tttggactcc tggacatctg cgttcaacac ccacagacaa ccgcttttcg ctcatctccg
7441 tcggagaggg gagtcacatg tttagtgaaa agatgatttt tcttccactc ttct
//