Typing tool
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Typing tool
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Complete norovirus genomes
| MK753033 | GII.1 | |
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| GII.P16 |
ORF1: 1..5100
ORF2: 5081..6688
ORF3: 6688..7461
LOCUS MK753033 7486 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P16-GII.1/Maricopa0357
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK753033
VERSION MK753033.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7486)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7486)
AUTHORS Barclay,L., Cannon,J.L., Pan,C.-Y., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7486
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Maricopa0357"
/isolate="Hu/US/2016/GII.P16-GII.1/Maricopa0357"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="11-Nov-2016"
/note="genotype: GII.P16-GII.1"
gene 1..5100
/gene="ORF1"
CDS 1..5100
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS54669.1"
/translation="MKKASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDEPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQ
PGVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
ISMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEV
EKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVK
TMEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKILVEKVKNTSVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEE
APKPEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYNEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPAGITEAFGVPIKQVQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTIICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAVALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 1..996
/gene="ORF1"
/product="p48"
mat_peptide 997..2094
/gene="ORF1"
/product="NTPase"
mat_peptide 2095..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3024
/gene="ORF1"
/product="VPg"
mat_peptide 3025..3567
/gene="ORF1"
/product="Pro"
mat_peptide 3568..5097
/gene="ORF1"
/product="RdRp"
gene 5081..6688
/gene="ORF2"
CDS 5081..6688
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS54670.1"
/translation="MKMASNDAAPSNDGAAGLVPEVNNETMALEPVAGASIAAPLTGQ
NNVIDPWIRMNFVQAPNGEFTVSPRNSPGEVLLNLELGPELNPFLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKLVFAAIPPHFPLENLSPGQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQQPEPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFNYLVPP
TVESKTKPFTLPILTIGELSNSRFPVPIDELYTSPNEGVVVQPQNGRSTLDGELLGTT
QLVPSNICALRGRINAQVPDDHHQWNLQVTNANGTPFDPTEDVPAPLGTPDFLANIYG
VTSQRNPDNTCRAHDGVLATWSPKFTPKLGSVVLGTWEEHDLDLNQPTRFTPVGLYDT
NHFDQWILPNYSGRLTLNMNLAPSVAPLFPGEQILFFRSHIPLKGGTSNGAIDCLLPQ
EWIQHFYQESAPSPTDVALIRYTNPDTGRVLFEAKLHRQGFITVANSGSRPIVVPPNG
YFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6688..7461
/gene="ORF3"
CDS 6688..7461
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS54671.1"
/translation="MAGAFVAGLAGDIVTNSIGSLVNAGANAINQKVDFENNKQLQQA
SFNHDKEMLQAQIQATKQLQADMIALRQGVLTAGGFSPTDAARGAVNAPMTQVLDWNG
TRYWAPGATKTTAFSGGFTSSPNTRTVDLPRKTSTTPAPTPISRSSSSASTVSTRSTI
VSGTSGLSSLTRSSFNSQPTSSSSRTSEWVRSQNRALEPYMRGALQTAYVTPPSSRAS
SNGTVSTVPKEVLDSWTSVFNTHRQPLFAHLRRRGESQA"
ORIGIN
1 atgaagaagg cgtctaacga cgctaccgtt gccgttgctt gcaacaacaa caacgacaag
61 gaaaaatctt caggtgaagg cttattcaca aatatgtctt ccaccttaaa gaaagccctc
121 ggggctaggc ccaaacagcc tgccccgaga gacgaaccac aaaagccccc aagaccacca
181 actcccgagt tggtcaagag gataccccct cctccaccta atggcgagga agaagaagaa
241 ccagtcatta ggtatgaggt taagagtggg atctctggcc tgcccgagct cacaacagtc
301 ccccaaccgg gcgtggccaa cacagcattc agtgttccac cactgagctt gagagaaaac
361 agggaggcca aagaaccgct aacaggggca atattagaga tgtgggatgg agagatatac
421 cactatggcc tgtacgtgga gaaaggctta gtgttgggtg tgcacaaacc acctgcagcc
481 ataagcatgg caagagtgga gttgacgccg ctgtcattgt actggcgtgt ggtgtacact
541 ccccaatacc tcatctcccc tgaaactctc aggaggctca acggagaggc gttcccttac
601 accgcctttg acaacaactg ctatgccttt tgctgctggg tgttagacct caatgactca
661 tggcttagca ggaggatggt gcaaagaaca acgggcttct tcagacctta ccaagagtgg
721 aacagaaaac ccctgcctac catggatgac tccaaaatca agaaggtagc aaatatattc
781 ctatgttcat tgtccacatt attcaccaga cccataaaag acctcatagg aaagattaaa
841 ccattaaaca tattgaacat cctggcaacg tgtgactgga cgtttgccgg aatagtggag
901 tctctgatat tacttgctga actcttcgga gttttctgga cacccccaga tgtgtctgct
961 atgatcgctc ccttactcgg ggactacgaa ctgcaagggc cagaagacct cgccgttgaa
1021 ctcgtacctg tggtaatggg agggattggt ttggtgttgg gattcaccaa agagaaaatt
1081 ggcaaaatgt tgtcctcagc agcatcaaca ctcagggctt gcaaagatct tggtgcctat
1141 ggcttagaga tactcaaatt ggtcatgaag tggttcttcc caaagaaaga ggaggccaat
1201 gagttagcca tggtgagggc catagaggat gccgtactag atcttgaggc aatagaaaat
1261 aaccacatga caaccctgtt gaaagacaaa gacagcttag caacatacat gaaaacactg
1321 gacatggagg aggagaaagc cagaaggttg tccacaaaat ctgcatcccc tgacatagtt
1381 gggacaatca acgccctgct ggctcgaata gcagcggcca ggtcattagt ccacagggcc
1441 aaggaagagc tgtctagcag gataagacca gtagttgtta tgatatctgg caaaccagga
1501 ataggcaaaa ctcatctggc cagggaggtg gcaagaaaag tggcatccac tctcacaggg
1561 gatcaaagag tcggactcat accaagaaac ggtgtggacc attgggatgc atacaaaggt
1621 gagagagtcg tgctgtggga cgactatggc atgagcaacc ccattcatga tgctcttcgc
1681 atacaagaat tggctgacac gtgtcccctt accttaaatt gtgacagaat tgaaaataag
1741 ggaaaagttt ttgacagtga ggtcataata atcacaacaa accttgccaa cccagcccca
1801 cttgattatg tcaactttga ggcctgttcc aggagaattg attttctggt gtacgctgag
1861 gcaccagaag tagaaaaggc aaaacgggac tttcctggtc agccagacat gtggaaggac
1921 gccttcaagc cggacttctc acacatcaag ctacagcttg cacctcaggg cggctttgac
1981 aagaatggca acaccccaca tgggaaggga gtgatgaaga ccctcactac cggttctctg
2041 attgcccgcg catcaggcct actgcatgag aggatggatg aatttgaact ccaaggtccc
2101 acaatcacca ccttcaattt cgaccggaac agaatcacag cattcagaca attggctgcg
2161 gaaaacaagt atggattggt ggataccatg aaagttggca atcaactaaa aggagtgaaa
2221 accatggaag aactcaaaca agcaatcagg aatgtgacca tcaagaggtg ccggatcatc
2281 tacggtggct ccacgtatga ccttgaatct gatggcaagg gcaaaatttt ggtggaaaag
2341 gtcaagaaca cctctgtaca gaccaacaac gagctggctg gggccctgca ccatctcaaa
2401 cacgcccgaa tcaggtacta tgtcaaatgt gtgcaagaag cagtctattc catcatacaa
2461 attgccggcg ctgcgtttgt caccacgcgc attgcacgcc gcatgaacat acaagaactc
2521 tggtcgaagc cacaattaga tcaaaatgaa tcagagacta aggaagaggc ccccaagcca
2581 gaagatgacg agttcatcat atcttctaag gacatcaagg aggaaggaaa gaagggcaaa
2641 aacaagactg gccgtggcaa gaaacacact gcattctcca gcaagggctt gagcgatgag
2701 gagtataacg agtacaagag gataagagaa gagagaaatg ggaagtactc tatagaggag
2761 tatcttcaag acagagacag gtactatgag gagctcgcca ttgccaaggc cacggaagaa
2821 gacttctgcg aagaggagga gatcaaaatc cgtcagagaa ttttccgtcc caccaggaaa
2881 caaagaaagg aagagagggc cacattaggg ctagtaacag gttcagaaat cagaaaaaga
2941 aaccctgatg acttcaaacc caaagggaag ctgtgggccg atgacaacag aagtgttgac
3001 tacaatgaga agctggactt tgaggccccc ccaagcatat ggtctaggat tgtgagcttt
3061 ggttccggtt ggggcttctg ggtatcacca agcctgttca taacatcaac tcatgtaatc
3121 cccgcaggca taacagaagc gtttggagtc cccatcaaac aagttcagat tcacaaatca
3181 ggtgaatttt gccgattcag attcccaaaa ccaattagac cagatgtgac aggaatgatc
3241 ttagaagagg gtgcgcctga aggcaccgta gcaactgtgc ttatcaaacg ccccaccgga
3301 gagctcatgc ctcttgcagc cagaatggga acacacgcaa ccatgaaaat tcaaggccgc
3361 atggttggcg gacagatggg tatgttgctc actggatcaa atgctaaagg aatggatttg
3421 ggaacaactc ctggtgactg tggctgtcct tacatctata aaaggggcaa tgactatata
3481 gtcattgggg tgcacactgc agcagcccgt ggtggaaaca ctatcatctg tgccacacag
3541 ggaagtgagg gtgaggcaac tcttgagggt ggagatgaca aaggaacata ctgtggagca
3601 cctattctag gccctggggg tgcaccaaaa ttgagcacca aaaccaaatt ttggaggtca
3661 tcgaacacgc cccttccacc agggacatat gagcctgcct acctcggtgg ccgtgatccg
3721 cgtgttaagg gtgggccctc cttgcagcag gtaatgagag accagttgaa gccattcact
3781 gaacccaggg gcaagcctcc aagaccaagt gtattggaag ctgccaaaca aaccattatc
3841 aacgtcctcg aacaaacctt ggaccctcca caaaaatgga catacgcgca ggcgtgtgca
3901 tcacttgaca aaaccacctc cagcgggcat ccccatcacg tccgaaagaa tgaattctgg
3961 aatggtgaga ccttcactgg caaattggca gaccaagcat caaaagcaaa ccttatgttt
4021 gaggaaggga aacacatgac accagtgtat acagcagcac tcaaggacga gctagtcaag
4081 actgagaaaa tctatggaaa gatcaagaag agactgctct ggggctctga cttgtccacc
4141 atgatccggt gcgctaggtc atttggtggg ctcatggacg agatgaaggc acactgcata
4201 tcactcccag tacgagttgg catgaatatg aatgaagatg gcccaataat atttgagaaa
4261 cattccagat acaaatacca ctatgatgca gactactctc gttgggattc aacacaacag
4321 agggcagtgc tagcagtagc cttggaaatc atggtcagat tctctgcaga accacaattg
4381 gcacaaatag tcgctgagga tctgctggcc cctagtgtag tagatgtggg agactttaaa
4441 atcacaataa atgaagggct cccatctggt gtgccatgca cttctcaatg gaactccatc
4501 gcacactggc tgctaactct ctgtgccttg tctgaagtca ccaaactgtc ccctgacatt
4561 atacaagcaa attccatgtt ctcattttac ggtgatgacg agattgtcag caccgacata
4621 aaattggacc ctgaacagtt aaccgccaaa ttgaaggagt acggcctgaa accaacccgc
4681 ccagacaaga ccgagggacc cctgattatc agtgaagatt tgaacggact cactttcctc
4741 cgaaggacgg tgactcgtga cccagctggc tggtttggaa aactggacca aagctcaatt
4801 ttgaggcaga tgtactggac tagaggacca aatcatgaag accccaatga gacaatgata
4861 ccccattctc aaagacccat acagctcatg gcactgcttg gtgaagcctc tcttcacgga
4921 ccctctttct acagtaaaat cagtaaattg gttataactg aactcaaaga aggtgggatg
4981 gacttttacg tgccaaggca ggaacccatg ttcagatgga tgaggttttc tgacttgagc
5041 acgtgggagg gcgatcgcaa tctggctccc aattttgtga atgaagatgg cgtcgaatga
5101 cgccgctcca tctaatgatg gtgcagccgg tctcgtacca gaggtcaaca acgagacgat
5161 ggcacttgag ccggtggctg gggcttctat agctgcccct ttaaccggcc aaaataatgt
5221 gatagacccc tggattagaa tgaattttgt ccaagctcca aatggtgaat ttacagtgtc
5281 cccccgtaat tccccaggtg aagtgttgtt gaatttggaa ttaggtcctg aactaaatcc
5341 attcctggca cacctttcaa gaatgtataa tggttatgct ggtggggttg aagtgcaggt
5401 gctacttgct gggaatgcgt tcacagcagg aaaactagtg tttgcagcaa tccccccaca
5461 tttccctctt gagaatttga gtcctggtca aattacaatg ttccctcatg tgattattga
5521 tgttagaact ttagaacctg tccttttgcc tttaccagat gttagaaata atttcttcca
5581 ttacaatcag cagcctgagc cccgtatgag acttgtggct atgttgtata ctcctctcag
5641 atctaatggc tctggtgatg atgtgttcac agtctcttgt agggtcctca cccgtccctc
5701 tccagacttt gattttaatt acttggttcc cccaactgtg gaatctaaaa ccaaaccatt
5761 taccctgcca atattaacca ttggagaatt gtcaaattct aggttcccag tgccaataga
5821 tgaattgtat accagtccca atgaaggagt ggttgtgcaa cctcaaaatg gcagatcaac
5881 acttgatggt gaactgcttg gcaccacaca acttgtacca tcaaacatct gcgccttgcg
5941 agggcgcatc aacgcccaag tgccagacga ccaccatcaa tggaacttgc aggttacaaa
6001 cgcaaatggg actcccttcg accccactga agatgtccct gcaccattgg gcacgccgga
6061 tttcttggca aacatctacg gagttactag ccagaggaat cctgacaaca cttgccgtgc
6121 ccatgatggg gtcttggcaa cctggagccc taaattcaca cccaagttag gctctgtggt
6181 tttgggtact tgggaagaac atgatcttga tcttaaccaa cccaccagat tcacacctgt
6241 tggtctgtat gatacaaacc actttgatca gtggattcta cccaactact ctggaagatt
6301 gaccttaaat atgaatttgg cgccctccgt tgctcccctt ttcccaggtg aacaaatact
6361 cttctttagg tcccacatac cacttaaagg aggcacttcc aacggtgcca ttgactgtct
6421 actccctcag gagtggatcc agcatttcta tcaggaatca gccccgtcac ccacagatgt
6481 tgctctgatt aggtacacca accctgacac gggccgtgtc ctttttgagg ccaaactaca
6541 tagacaggga ttcatcacag tagcaaattc tggttctaga cctattgttg tcccccctaa
6601 tggttatttt aggtttgatt cttgggttaa tcagttttac tctctcgccc ccatgggaac
6661 tgggaatggg cgtagaagag tgcagtaatg gctggagctt ttgtagcagg ccttgccggt
6721 gatatagtca ccaatagcat tggttcactt gtgaacgctg gagccaatgc aataaaccaa
6781 aaagtagact ttgaaaacaa caaacaacta cagcaggcct ctttcaacca tgacaaggaa
6841 atgttgcaag ctcaaattca ggccacaaaa caattacagg ctgacatgat tgcgctcaga
6901 caaggggtgt tgaccgcagg cggcttctcc cctactgatg cagcaagagg ggcggttaat
6961 gcgcccatga cgcaagtctt ggactggaat gggacgaggt actgggcccc cggagccacc
7021 aaaacaactg ctttctccgg tgggttcaca agctctccca acaccaggac tgttgatttg
7081 cctaggaaaa catcaaccac accagccccc acacctatat ctagatctag ttcttctgct
7141 tctactgttt ctacccgctc aacaattgtc agcgggactt ctggcctttc ttctttgact
7201 aggagctctt ttaattccca gcccacctcc tcttcttctc ggactagcga atgggtgcgt
7261 agtcaaaaca gggcgctgga gccctacatg aggggagcac tgcaaactgc ttacgtgacg
7321 cctccctcta gtagagcatc cagcaatggc acagtctcaa ccgtgccaaa agaagttttg
7381 gactcctgga catctgtgtt caacacccac agacaaccgc ttttcgctca tctccgtcgg
7441 agaggggagt cacaggctta gtgaaaagat gatttttctt ccactt
//