Typing tool
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Typing tool
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Complete norovirus genomes
| MK753031 | GII.2 | |
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| GII.P2 |
ORF1: 1..4875
ORF2: 4856..6484
ORF3: 6484..7239
LOCUS MK753031 7239 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P2-GII.2/Yolo0348
nonstructural polyprotein (ORF1) gene, partial cds; VP1 (ORF2)
gene, complete cds; and VP2 (ORF3) gene, partial cds.
ACCESSION MK753031
VERSION MK753031.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7239)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7239)
AUTHORS Barclay,L., Cannon,J.L., Pan,C.-Y., Montmayeur,A.M., Tatusov,R.L.,
Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7239
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Yolo0348"
/isolate="Hu/US/2016/GII.P2-GII.2/Yolo0348"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="16-Aug-2016"
/note="genotype: GII.P2-GII.2"
gene <1..4875
/gene="ORF1"
CDS <1..4875
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS54664.1"
/translation="GDEPTVMFSTAGGVSGLPELTTVGQPPEANTAFSVPPLSQRENR
DAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISIAKVELTPLSLYWRPVY
TPQYLISPDTLRKLHGELFPYTAFENNCYAFCCWVLDLNDSWLSRRMISRTTGFFRPY
QEWNRKPLPTMDDSKLKKVANIILCALSSLFTRPIKDIIGKLKPLNILNILASCDWTF
AGIVESLILLAELFDVFWTPPDVSAMIAPLLGDYELQGPEDIAVELVPVVMGGIGLVL
GFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKDEANELAMVRAIEDA
VLDLEAIENNHMTTLLKDKNSLAAYMKTLDMEEEKARKLSTKSASPDIVGTINALLAR
IAAARSLVHRAKEELSSRPRPVVLMISGKPGIGKTHLARELAKKIASTLTGDQRVGLI
PRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLTLNCDRIENKGKVFD
SDAIIITTNLVNPAPLDYVNFEACSRRIDFLVYADAPEVEKAKRDFPGQPDMWKDAYR
SDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTASSLVARASGLLHERLDEYELQGPP
LSTFNFDRNKIAAFRQLAAENKYGLVDTMRVGNQLRNVTTMDELKKAIKNIIIRKCQI
VYGGNTYTLESDGKGKVVVERVQSASVQINNEIAGAVHHLRCARIRYYVKCAQEAIYS
LLQIAGTVFVTSRIVSRMNIQNLWSRPLSEDADEATIKEGCPKPRDEEEFIVSSDDIK
PEGKKGKNKSGRGKKHTAFSSKGLSDEEYEEYKRIREERNGKYSIEEYLQDRDKYYEE
VAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERANLGLVTGSEIRKRNPDDFKPKG
KLWADDDRSVDYNERISFEAPPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPQGITEA
FGVPIRQVQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEGTVATILIKRTTGELMPL
AARMGTHATMRIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDYIVIG
VHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAPKLSTKTKFWRSS
TTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLEAAKKTI
INVLEQTIDPPQKWTYAQACASLDKTTSSGYPHHVRKNEHWNGESFTGKLADQASKAN
LMFEEGKHMTPVYTAALKDELVKTEKVYGRIKKRLLWGSDLATMVRCARSFGGLMDEL
KAHCVTLPIRVGMNMNEDGPIVFEKHSRYRYHYDADYSRWDSTQQRAVLAAAMEIMVK
FSAEPQLAQIVAEDLLSPSVVDVGDFKVSINEGLPSGVPCTSQWNSIAHWLLTLCALS
EVTDLSPDIVQANSLFSFYGDDEIVSTDIKLDPEKLTGKLREYGLKPTRPDKTEGPLI
ISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLFWTKGPNHEDPFESMIPHSQRPI
QLMSLLGEAALHEPSFYSKISKLVISELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGD
RNLAPSLVNEDGVE"
mat_peptide <1..765
/gene="ORF1"
/product="p48"
mat_peptide 766..1863
/gene="ORF1"
/product="NTPase"
mat_peptide 1864..2400
/gene="ORF1"
/product="p22"
mat_peptide 2401..2799
/gene="ORF1"
/product="VPg"
mat_peptide 2800..3342
/gene="ORF1"
/product="Pro"
mat_peptide 3343..4872
/gene="ORF1"
/product="RdRp"
gene 4856..6484
/gene="ORF2"
CDS 4856..6484
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS54663.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDSKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6484..>7239
/gene="ORF3"
CDS 6484..>7239
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS54665.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPSSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTASSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMRGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHPP"
ORIGIN
1 ggggacgaac caaccgtgat gtttagtact gcaggtggtg tgtctggcct acctgagctc
61 acaacagtcg gtcaaccacc tgaagctaac actgccttta gtgtgccccc ccttagccaa
121 agggagaaca gggacgctaa ggaaccgtta actggggcta ttctggaaat gtgggatggg
181 gagatttatc attatggact gtatgtggaa aaagggcttg tgctaggcgt gcacaagccg
241 ccggctgcca tcagcatagc caaagtggaa ttaacacccc tctcactgta ttggaggcct
301 gtgtacacgc ctcagtacct catatctcct gacaccttga ggaaactcca cggtgagtta
361 tttccctata cagcctttga aaacaactgt tatgccttct gttgttgggt tttggacctc
421 aacgattcat ggctaagcag gaggatgatt agtaggacta ctggcttctt taggccctac
481 caagagtgga acaggaagcc tctcccaact atggatgact caaaattgaa gaaggtcgca
541 aacatcattc tgtgtgcatt gtcatcattg ttcactaggc ccattaagga tataattggc
601 aaacttaaac cccttaacat cctaaatatt ctggcctcat gcgattggac cttcgctggc
661 atagtagaat cactaatcct cttggctgaa ctctttgatg tgttctggac acccccagat
721 gtgtctgcaa tgatcgcacc cctcctcggc gactatgagc tacaaggtcc cgaagacatc
781 gctgtggagc tcgtgcccgt tgtgatgggt gggataggtc tggtgttggg attcaccaaa
841 gagaaaatag gcaagatgct ctcctctgca gcgtcaaccc tgagggcttg caaagatctt
901 ggagcctatg gattggagat actgaaacta gtcatgaaat ggtttttccc aaagaaggat
961 gaggccaacg aactggctat ggttagagcc attgaagacg ctgtattaga cctggaggct
1021 attgagaaca accatatgac cactctatta aaagacaaga acagccttgc agcatacatg
1081 aagaccctgg acatggaaga ggaaaaagct aggaagctat ccaccaaatc agcctcccct
1141 gacattgtgg gcactataaa cgccctgctg gctaggatcg ctgccgcgcg ttccctagtt
1201 catagggcca aggaggagct ctccagcagg ccaagaccgg tcgttttgat gatctctggc
1261 aagccaggga taggaaagac ccacttggcc agagaactgg caaagaaaat tgcctcgaca
1321 ctcacaggag accaaagggt tggtctcatc ccacggaatg gagttgacca ttgggacgcc
1381 tacaaaggtg agagagtggt gctctgggat gactatggaa tgagcaaccc catccacgat
1441 gcgctgaggc tgcaggaatt ggcagacaca tgtccactaa ctctaaattg tgacaggatt
1501 gaaaacaaag ggaaagtctt cgacagcgac gcgatcataa tcaccaccaa tttggtcaac
1561 cccgcgccgc tggattatgt caactttgag gcctgctcca gacgtataga cttccttgtg
1621 tatgctgatg ccccagaagt cgagaaagca aagcgggact ttcccggtca accggacatg
1681 tggaaagacg cctatcgatc tgacttctca cacattaaac tacaacttgc accacaaggt
1741 gggtttgaca aaaatggtaa caccccacat ggtaaaggag tgatgaagac tctcactgcc
1801 agctcactgg tcgcacgtgc ctctggtctc ttgcacgaga gattagatga gtacgagttg
1861 caaggtccgc ccctctcaac cttcaacttt gaccgtaaca aaatcgcagc gttcagacaa
1921 ctcgccgctg aaaacaagta cggtctggta gacacgatga gggtgggcaa ccagctcaga
1981 aatgtcacga ccatggatga actcaagaag gctatcaaga acatcataat cagaaagtgc
2041 cagatagtct atggtggcaa cacttacacg cttgagtctg acggcaaggg caaggttgta
2101 gttgagaggg tgcagagcgc cagcgtgcaa atcaacaatg agatcgctgg tgcagtacac
2161 catcttagat gtgccagaat aaggtattat gtcaagtgtg cccaagaggc catatactca
2221 ctcctccaaa ttgctggcac ggtgtttgtc acttcacgca tcgtaagccg catgaacatc
2281 caaaatctgt ggtctaggcc actatctgaa gatgcagatg aagccaccat aaaagagggg
2341 tgccctaaac ctagggatga agaagaattc atcgtctcct cagatgatat taagccagag
2401 ggcaagaaag gcaaaaacaa gagtggccgg ggcaagaaac acacggcatt ctcaagtaaa
2461 gggctcagtg atgaggagta cgaagagtac aaaagaatca gagaggagag aaatggcaag
2521 tactccatag aggaatacct acaggacaga gacaagtact atgaagaggt ggccattgcc
2581 agggcaactg aagaagactt ctgtgaagaa gaagaggtta agattcgtca gaggatcttc
2641 aggccaacaa gaaagcaacg caaggaagaa agagccaacc ttggcctcgt taccgggtct
2701 gagatcagga agagaaaccc agatgacttc aaaccaaaag gaaagctatg ggccgacgat
2761 gacaggagcg tcgactacaa tgaaagaatc agctttgagg ctccaccaag catttggtct
2821 agaattgtca actttggttc tggatggggg ttctgggtgt cacctagcct cttcataaca
2881 tcaacacacg tcatacctca aggcataact gaggcctttg gtgtacccat aaggcaggtg
2941 caaatacaca aatcgggcga gttctgtcgc ttgagattcc caaaacccat cagaacagat
3001 gtgtcaggca tgatactgga ggagggagcg cccgaaggta ctgttgccac catactcatc
3061 aaaagaacca ctggagagct gatgcctcta gcagcaagaa tgggaaccca cgcgaccatg
3121 aggatacaag ggcgcacagt gggcggccag atgggaatgt tgctcactgg gtccaatgca
3181 aagagcatgg atcttggcac cacgcccggt gactgtgggt gtccctacat ttacaaaagg
3241 ggtaatgatt acatagtcat tggagttcac acagcagccg ctcgtggcgg aaacactgtc
3301 atctgcgcca cacaaggtag tgagggtgag gctactctcg agggtggtga caataaagga
3361 acatattgtg gggcaccaat cttgggcccc ggaaatgccc caaaactgag cactaaaacc
3421 aagttctgga ggtcctctac aacaccactc ccacccggca cgtacgagcc ggcatatctg
3481 ggaggaaaag acccccgagt caaaggtggg ccatctctgc aacaagtcat gcgagaccaa
3541 ctgaagccat tcaccgaacc ccgtggcaag ccaccaaaac caagtgtcct tgaagctgcc
3601 aaaaagacaa ttattaatgt gttagagcaa acaatagatc ccccacagaa gtggacgtac
3661 gcgcaagcgt gcgcgtctct tgacaaaacc acatctagtg ggtaccccca ccacgtgcgc
3721 aaaaacgagc actggaatgg ggaatctttc acaggaaaat tggctgatca ggcatcgaag
3781 gcaaacctaa tgtttgagga ggggaagcac atgaccccag tttatacagc tgcccttaag
3841 gatgagttgg ttaaaactga gaaagtgtat gggaggataa agaagaggtt actttggggc
3901 tctgacttgg ccaccatggt gaggtgtgcg cgctcctttg gcggtttgat ggacgaactc
3961 aaggcccact gcgtgacact cccgataagg gttggcatga atatgaatga agatggacca
4021 atagtctttg agaaacattc cagatacagg tatcactatg atgcagacta ctccaggtgg
4081 gattcaacac agcagagagc cgttctggcc gcggccatgg agattatggt caaattctca
4141 gcagaaccac aattagccca aatagttgca gaggatctgt tgtcgcccag tgttgttgac
4201 gtgggcgact tcaaagtttc catcaatgaa ggattaccat cgggtgttcc ttgcacctct
4261 caatggaact ccatcgcaca ctggctcctc accttgtgtg ccctttctga agttacagac
4321 ctctctcctg acattgtgca agccaactcc ctcttctcct tctatggtga tgatgaaatt
4381 gtgagtacag atatcaaatt agacccagaa aagttgacgg ggaagttgag agaatatggt
4441 ctcaaaccca cccgtcctga caaaactgag ggtcccttga ttattagcga ggatctgaat
4501 ggcctgacct tcctgaggag aactgtcacc cgcgaccctg caggatggtt tggcaaactg
4561 gaccaaagct ccatacttag gcaattgttt tggaccaaag gccctaatca tgaagacccc
4621 tttgagtcaa tgattccaca ttcccagagg cccatacaac tcatgtcact cttgggtgaa
4681 gcagcactgc atgaaccatc attttacagc aagatcagca agcttgtgat atctgagttg
4741 aaagaaggtg gaatggattt ttacgtgccc aggcaagaac ctatgtttag gtggatgaga
4801 ttctcggatt tgagcacgtg ggagggcgat cgcaatcttg ctcccagtct tgtgaatgaa
4861 gatggcgtcg aatgacgccg ctccatctac tgatggtgca gccggcctcg tgccagaaag
4921 taacaatgag gtcatggctc ttgaacccgt ggctggtgcc gccttggcag ccccggtcac
4981 cggtcaaaca aatattatag acccttggat tagagcaaat tttgtccagg cccccaatgg
5041 tgaatttaca gtctctcccc gaaatgcccc tggtgaagtg ctactgaatc tagagttggg
5101 tccagaatta aatccttatc tggcacattt agcaagaatg tacaatgggt atgccggtgg
5161 gatggaggtg caggtcatgt tggctgggaa cgcgttcaca gccggcaagt tggtcttcgc
5221 cgccgtgcca cctcacttcc cggttgaaaa ccttagccca caacaaatca ccatgttccc
5281 tcatgtgatc atagatgtga gaaccttgga acctgtttta ttaccactcc ctgatgttag
5341 gaataatttc ttccattata atcagaaaga tgattccaag atgagaattg tggctatgct
5401 ttataccccc ctcaggtcta atggttcagg tgatgatgtg ttcacagtct cctgcagagt
5461 gttgactaga ccttcccctg attttgactt cacatacctg gtgccaccaa cagtggagtc
5521 taaaacaaaa ccattcaccc tcccaatcct cacacttggg gaactttcca attctaggtt
5581 cccagtgtcc atagaccaga tgtacaccag ccctaatgaa gttatatcag tgcagtgtca
5641 aaatggtagg tgcacattgg acggggagct ccaagggaca acacaactcc aagtcagtgg
5701 catttgtgct ttcaaaggtg aagtgaccgc ccacttgcat gacaatgatc acctatataa
5761 tgttaccatc acaaatttga atgggtcccc ttttgatccc tccgaggata tccccgcccc
5821 cctgggtgtg cctgatttcc agggaagggt ctttggtatc atctcccaaa gagacaaaca
5881 caatagtccc gggcataatg aaccagcaaa caggggacac gacgctgtgg ttcctactta
5941 cacagcacag tacactccaa aactgggaca aattcaaatt ggcacatggc agactgacga
6001 ccttacagtc aatcaaccag tcaaattcac cccagttgga ctcaatgaca ctgaacattt
6061 taaccaatgg gtggtcccta ggtatgctgg tgccctaaat ctcaacacaa accttgcccc
6121 ttctgttgct ccagtatttc caggagagcg cctgctcttc ttcagatcat acattcccct
6181 caagggtggt tatggaaacc cagccattga ttgcctacta ccacaagagt gggtgcaaca
6241 cttctatcag gaagcagccc cttcaatgag tgaggtggcc cttgtcagat acatcaaccc
6301 ggatactggt cgggcactgt ttgaggccaa gcttcacaga gctggtttca tgacagtctc
6361 gagcaacacc agtgccccgg tggtcgtgcc tgccaacgga tacttcagat ttgattcttg
6421 ggtgaatcaa ttctattctc tcgcccccat gggaactggg aatgggcgta gaagggttca
6481 ataatggctg gagcttttgt agctggtctt gcaggggacg tgctaagtaa tgggctcagt
6541 tcattaatca atgcaggtgc taatgcaata aaccagaggg cagaatttga ttttaatcag
6601 aaattgcagc aaaattcttt taatcatgat aaggagatgt tgcaggctca gattcaggca
6661 actaagcagc tgcaggcaga catgatggct attaaacaag gggtcttgac cgctggcggt
6721 ttttcccctg ctgatgcagc cagaggtgct gtgaacgcgc ccatgacaca ggcgctggat
6781 tggaatggca caagatattg ggcaccaagc tccatgagga ccacatctta ttctggaaaa
6841 ttcacatcaa ccgccccagt gaggcaggcc gactttcagc acacccaaag ccggccttcg
6901 agtggttctt ctgtgtcttc ctttgccact cagtcttcaa ggccaactct gaccacaacc
6961 actggctcct cacatggcac agcctcatca aattcaactc gcagcacaag cctctcccag
7021 tcaacggtct ccagagctac atctaggact ggtgagtggg ttagggatca aaatagaaat
7081 ttggaaccct acatgcgtgg tgccttacag acagcctttg tcaccccacc ttccagcagg
7141 gcgtctgacg ggacagtctc aaccgtcccg aaaggtgttt tggactcctg gacacctgcg
7201 ttcaacaccc gtaggcagcc gctttttgca cacccccca
//