Typing tool
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Typing tool
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Complete norovirus genomes
| MK753020 | GII.13 | |
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| GII.P16 |
ORF1: 1..5066
ORF2: 5047..6675
ORF3: 6675..7409
LOCUS MK753020 7417 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2014/GII.P16-GII.13/HoodRiver0913
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK753020
VERSION MK753020.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7417)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7417)
AUTHORS Barclay,L., Cannon,J.L., Tsaknaridis,L.J., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7417
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="HoodRiver0913"
/isolate="Hu/US/2014/GII.P16-GII.13/HoodRiver0913"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="25-May-2014"
/note="genotype: GII.P16-GII.13"
gene <1..5066
/gene="ORF1"
CDS <1..5066
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QBS47719.1"
/translation="VACNNNNDKEKSSGEGLFTNMSSTLKKALGARPKQPAPRDNSQK
PPRPPTPELVKRMPPPPPNGEEEEPVIRYEVKSGISGLPELTTVPQPDVANTAFSVPP
LSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISMAKVELTPLS
LYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLSRRMVQRT
TGFFRPYQEWNRKPLPTVDDSKIKKVANIFLCSLSTLFTRPIKDLMGKIKPLNILNIL
ATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPVVM
GGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAM
VRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLSTKSASPDIVGT
INALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAREVARKVASTLTG
DQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADTCPLTLNCDRIE
NKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPD
MWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERMDE
FELQGLTVTTFNFDRNRIAAFRQLAAENKYGLVDTMRVGNQLKGVKTMEELKQAIKNV
TIKRCRIIYGGSTYDLESDGKGRVLVEKVKNTSVQTNNELAGALHHLKHARIRYYVKC
VQEAVYSIIQIAGAAFVTTRIVRRMNIQELWSKPPLDQNESEAKEEAPKSEDDEFIIS
SKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRD
RYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERVTLGLVTGSEIRKRNPDD
FKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSLFITSTHVIPA
GITEAFGVPIKQIQVHKSGEFCRFRFPKPIRSDVTGMILEEGAPEGTVATVLIKRPTG
ELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGND
YIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPGGAPKLSTKTK
FWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPPRPSVLEA
AKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFWNGETFTGKLADQ
ASKANLMFEEGKHMTPVYTAALKDELVKTDKVYGKIKKRLLWGSDLSTMIRCARSFGG
LMDEMKAHCITLPVRVGMNMNEDGPIVFEKHSRYKYHYDADYSRWDSTQQRAVLAAAL
EIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKISINEGLPSGVPCTSQWNSIAHWLLT
LCALSEVTKLSPDIVQANSMFSFYGDDEIVSTDIKLDPEKLTTKLKEYGLKPTRPDKT
EGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNHEDPNETMIPH
SQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLS
TWEGDRNLAPNFVNEDGVE"
mat_peptide <1..962
/gene="ORF1"
/product="p48"
mat_peptide 963..2060
/gene="ORF1"
/product="NTPase"
mat_peptide 2061..2591
/gene="ORF1"
/product="p22"
mat_peptide 2592..2990
/gene="ORF1"
/product="VPg"
mat_peptide 2991..3533
/gene="ORF1"
/product="Pro"
mat_peptide 3534..5063
/gene="ORF1"
/product="RdRp"
gene 5047..6675
/gene="ORF2"
CDS 5047..6675
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47720.1"
/translation="MKMASNDAAPSNDGAASLVPEAINETMPLEPVAGASIAAPVAGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAIPPNFPVDMISPAQITMLPHLIVDVRTLEPIMIPLPD
VRNVFYHFNNQPQPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFIYLVPP
SVESKTKPFTLPILTISELTNSRFPIPIEQLYTAPNENNVVQCQNGRCTLDGELQGTT
QLLSSAVCSYRGRTVANSGDNWDQNLLQLTYPSGASYDPTDEVPAPLGTQDFSGILYG
VLTQDNVSEGTGEAKNAKGVYISTTSGRFTPKIGTIGLHSITENVHPNQQSRFTPVGV
AQNENTPFQQWVLPHYAGALALNTNLAPAVAPTFPGEQLLFFRSRVPCVQGLRGQDAF
IDCLLPQEWVNHFYQEAAPSQADVALIRYVNPDTGRTLFEAKLHRSGFITVSHTGTYP
LVVPPNGHFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6675..7409
/gene="ORF3"
CDS 6675..7409
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47721.1"
/translation="MAGAFIAGLAGDMLTSAVGSLTSAGANAINQKLNFDYNKQLQNA
SFQHDKEMLQAQIDATKKLQSEMIAIKHGVLTAGGFSPADAARGAVNAPMTRVLDWSG
TRYYAPNSVQTTSYSGQFTPSPVHRAQVKSPSNSSQRAAAPSSIRSLSTQSTSLGSTS
SGGSSTISSSSRTANWVQQQRALSPYMQGALQTAYVTPPSSRTSSMSSVSTVPKGVLD
SWTPVFNTRRQPLFAHLRKRGESQVY"
ORIGIN
1 ccgttgcttg caacaacaac aacgacaagg aaaaatcttc aggtgaaggc ttattcacaa
61 acatgtcttc caccttaaag aaagccctcg gggcccggcc caaacagcct gccccgaggg
121 acaactcaca aaagccccca agaccaccaa ctcccgagtt ggttaagagg atgcctcctc
181 ccccacctaa cggagaagag gaagaaccag tcattaggta tgaggttaag agtggaatct
241 ctggcctgcc cgagctcaca acagtccctc aaccggatgt ggccaacacg gcattcagtg
301 tcccaccgct gagcttgaga gaaaacaggg aggccaagga accgctgaca ggggcaatat
361 tagagatgtg ggatggagag atataccact atggcctgta cgtggagaaa ggcttagtgt
421 tgggtgtgca caaaccacct gcagctataa gcatggcaaa agtggagctg acgccgttgt
481 cattgtactg gcgtgtggtc tacacccccc aatacctcat ctcccctgaa actctcagga
541 ggctcaacgg agaggcattc ccctacactg cctttgacaa caactgctat gccttttgct
601 gttgggtgtt agacctcaat gactcatggc ttagcaggag gatggtgcaa agaacaacag
661 gcttcttcag accttaccaa gagtggaaca gaaaacccct gcccactgtg gatgactcca
721 aaatcaagaa ggtggcaaac atattcctgt gctcactgtc cacgttgttc accagaccta
781 taaaagacct catgggaaaa attaagccat taaacatctt gaacatcctg gcaacgtgtg
841 actggacatt cgccggaata gtggagtctc ttatattgct tgctgaactc tttggagttt
901 tctggacacc cccagatgtg tctgctatga tcgctccttt acttggagac tacgagttgc
961 aagggccaga agaccttgcc gttgagctcg tacctgtagt aatgggaggg attggtttgg
1021 tgttgggatt caccaaagag aaaattggaa aaatgttgtc ctcagcagca tcaacgctca
1081 gggcttgtaa agatcttggt gcctatggct tagagatact caaactggtc atgaagtggt
1141 tcttcccaaa gaaagaagag gccaatgagc tagccatggt gagagctata gaggatgctg
1201 tactagatct tgaggcaata gaaaataatc acatgacaac tctgttgaaa gacaaagaca
1261 gcctggcaac ctacatgaaa acactagaca tggaggagga aaaggccaga agattgtcca
1321 caaaatctgc atcccctgac atagttggga cgatcaacgc cctgctggct cgaatagcag
1381 cggctaggtc actagtccac agggccaagg aggagttatc tagcaggata agaccagtgg
1441 ttgttatgat atctggcaaa ccagggatag gcaaaactca tttggccagg gaagtggcaa
1501 gaaaggtggc atccactctc acaggggatc aaagagtcgg gctcataccg agaaacggtg
1561 tggaccattg ggatgcatac aaaggtgaga gagtcgtgct atgggacgac tatggcatga
1621 gcaaccccat tcatgatgct ctgcgcatac aagaattggc tgacacgtgt ccccttacct
1681 taaattgtga cagaattgaa aataagggaa aggtttttga cagtgaagtc ataataatca
1741 caacaaacct tgccaatcca gctccacttg attatgtcaa ctttgaggcc tgttccagga
1801 gaattgactt cctggtgtac gccgaggcac cagaagtaga aaaggcaaaa cgagactttc
1861 ctggtcaacc agatatgtgg aaggacgcct tcaagtcgga cttttcacat atcaagctgc
1921 aacttgcacc tcagggcggc tttgacaaga atggcaacac cccacatggg aaaggagtga
1981 tgaagaccct caccaccggt tcactgatcg cccgtgcatc aggcttactg catgagagga
2041 tggatgaatt tgaactccaa ggcctcacag tcaccacctt taattttgac cggaacagaa
2101 tcgctgcatt cagacaattg gctgcagaaa acaagtatgg attggtggac accatgagag
2161 ttggcaatca attaaaaggg gtgaaaacca tggaagaact caaacaagca atcaagaatg
2221 tgaccatcaa gaggtgccgg atcatctacg gcggctccac gtatgacctt gaatctgatg
2281 gtaagggcag agttctggtg gaaaaggtca agaacacctc tgtgcagacc aacaacgagt
2341 tggccggagc cctgcatcac ctcaaacatg cccgaatcag gtactatgtc aaatgtgtgc
2401 aagaagcagt ctactctatt atacaaatcg ccggcgctgc gtttgtcacc acacgcatag
2461 tacgccgcat gaacatacaa gagctttggt cgaagccacc attagatcaa aatgaatcag
2521 aggctaagga agaggccccc aagtcagaag atgacgagtt catcatatct tctaaggaca
2581 tcaaggagga aggaaagaag ggcaaaaaca aaactggccg tggcaagaaa catactgcat
2641 tctctagcaa gggcttgagc gatgaggagt acgacgagta caagaggata agagaagaga
2701 gaaatgggaa gtactctata gaggagtatc ttcaagacag agacaggtac tatgaggaac
2761 tcgccatcgc caaggccacg gaagaagact tctgtgagga ggaggagatc aaaatccgtc
2821 agaggatctt ccgtcccacc aggaagcaaa ggaaggaaga gagggtcaca ctagggctag
2881 taactggttc agaaatcaga aaaagaaacc ctgatgactt caaacctaaa gggaaactgt
2941 gggctgatga caacagaagt gttgactaca atgagaaact ggactttgag gcccccccaa
3001 gcatatggtc taggattgtg agttttggtt ctggttgggg tttctgggtg tcaccaagcc
3061 tgttcataac atcaactcac gtaatccctg caggcataac agaggcattt ggtgtcccca
3121 tcaaacaaat ccaggtccac aaatcaggtg aattttgccg gttcagattc ccaaaaccaa
3181 ttagatcaga tgtgacagga atgatcttgg aagaaggtgc gcctgagggc accgtggcaa
3241 ccgtgctcat caaacgccct accggagagc tcatgcccct tgcagccaga atgggaacac
3301 acgcaaccat gaaaattcag ggccgcatgg ttggcggaca gatgggtatg ttgctcactg
3361 gttcaaatgc taaaggaatg gatttaggaa caactcctgg tgattgtggc tgtccctaca
3421 tctacaaaag gggcaatgac tatatagtca ttggggtgca cacagcagca gcccgtggtg
3481 gaaacaccgt catctgtgcc acacagggaa gtgagggtga ggcaaccctt gagggtggag
3541 atgacaaagg aacatactgt ggggcaccca ttctaggccc cgggggggca ccaaaattga
3601 gcaccaaaac caaattttgg aggtcatcga acacgcctct tccaccaggg acgtatgagc
3661 ctgcctacct cggtggccgt gacccgcgtg ttaagggtgg gccctccttg cagcaggtaa
3721 tgagagacca gttgaagcca ttcaccgagc ccaggggtaa acctccaaga ccaagtgtgt
3781 tggaagcagc caaacaaacc atcatcaacg tcctcgaaca aactctggac cctccacaaa
3841 aatggacata cgcacaggcg tgtgcttcac ttgacaaaac cacctccagc gggcaccccc
3901 accatgtccg aaagaatgaa ttctggaatg gtgagacctt cactggtaaa ttggcagacc
3961 aagcatcaaa agcaaatcta atgtttgagg aagggaaaca catgacacca gtgtatacag
4021 cagccctcaa ggatgagctg gtcaagactg acaaagtcta tggaaagatc aagaagagac
4081 tgctctgggg ctctgacttg tccaccatga tccggtgcgc caggtccttt ggtgggctca
4141 tggatgagat gaaagcacac tgcataacac tcccagtccg agttggcatg aacatgaatg
4201 aagatggtcc aatagtattt gagaagcact ccagatacaa gtatcactat gatgcagatt
4261 actcccgctg ggattcaaca caacagaggg cagtgctagc agcagccttg gagatcatgg
4321 tcaggttctc tgcggagcca caattggcac aaatagtcgc tgaggatctg ctggccccca
4381 gtgtggtaga tgtaggagac tttaaaattt caataaatga agggctcccc tctggtgtac
4441 catgcacttc tcaatggaat tccatcgcac actggctgct aaccctctgc gccttgtctg
4501 aagtcaccaa actgtcccct gacattgtac aggcaaactc catgttctca ttttacggtg
4561 atgacgagat tgtcagcacc gatataaaat tggaccctga aaagttaacc accaaattga
4621 aggagtacgg cctgaaacca actcgcccag acaaaaccga gggacccctg atcatcagtg
4681 aggatttgaa cggactcact ttcctccgga gaacggtgac tcgtgaccca gctggctggt
4741 ttggaaaatt ggaccaaagc tcaatattga ggcagatgta ctggactaga ggaccaaatc
4801 atgaagaccc caacgagaca atgatacccc actctcaaag acccatacag ctcatggcac
4861 tgcttggtga ggcctccctt cacggaccct ctttctacag caaaattagt aagttggtca
4921 taactgaact caaagaaggt gggatggatt tttacgtgcc aaggcaggaa cccatgttca
4981 ggtggatgag gttttctgac ttgagcacgt gggagggcga tcgcaatctg gctcccaatt
5041 ttgtgaatga agatggcgtc gaatgacgcc gctccatcga atgatggtgc agctagtctc
5101 gtaccagagg ccattaatga gactatgccg ttggaacccg ttgctggcgc atctattgct
5161 gccccagtgg cgggacaaac taacataatt gacccctgga taagaacaaa ttttgtgcaa
5221 gcccctaatg gagagttcac agtatcaccg agaaattccc ctggagagat tctattaaat
5281 ttagagttag gaccagattt gaatccttat ttggcccatc tgtcaaggat gtataatgga
5341 tatgctggag gtgttgaggt gcaagtgctt cttgctggga acgcgttcac agcaggaaag
5401 atattatttg cagcaatccc acccaacttt cctgtagata tgattagccc agctcaaatt
5461 actatgcttc cccatttgat tgtagatgtt aggacattgg agcctattat gataccctta
5521 ccagatgtta ggaatgtgtt ctatcatttt aacaatcaac cccaacctag gatgagatta
5581 gtggctatgc tctatacccc attgagatct aatggttcag gagatgatgt ctttactgtg
5641 tcttgtagag tgttgactag gccaacccct gactttgaat tcatttacct agtgcctccc
5701 tctgtagagt ccaaaactaa accattcaca cttccaatat tgaccatttc tgaactaacc
5761 aactcccggt ttcccatccc aattgagcaa ctgtacacgg ccccaaatga gaataatgtt
5821 gtgcagtgtc aaaatggaag gtgcaccttg gatggagagc ttcagggcac cacccagctg
5881 ctatcaagtg cagtttgctc ttacaggggt aggactgtgg ctaacagtgg ggacaattgg
5941 gaccagaatt tgctccagct gacctaccca agcggtgcaa gctatgaccc cactgatgaa
6001 gtaccagcac ccttgggcac ccaggatttc agtgggatat tgtatggggt gttaacccaa
6061 gacaatgtaa gtgagggtac aggggaggcc aaaaatgcta agggagtata catatccacc
6121 accagtggaa gattcacccc aaaaattgga acaattggat tgcattcaat aactgaaaat
6181 gtgcacccca atcagcaatc acggttcacc cccgttggag ttgctcagaa tgaaaatacc
6241 cccttccagc aatgggttct accacactac gcaggtgctc ttgctctaaa caccaatttg
6301 gcacccgctg ttgccccgac tttccctggc gagcaattac tgttcttcag gtcccgtgtt
6361 ccatgtgttc aaggtctgcg ggggcaggat gctttcatag attgtctcct acctcaagag
6421 tgggtgaacc atttttatca agaggctgct ccctcccaag cagatgttgc cctcatcagg
6481 tatgtcaacc ctgatactgg tcgcacgctg tttgaggcta aattgcacag gtcaggtttc
6541 atcactgtgt cacacactgg tacctacccc cttgtggtcc ccccaaatgg tcatttcagg
6601 tttgattctt gggttaacca attctactca ctcgccccca tgggaactgg caatgggcgt
6661 agaagagttc aataatggca ggagcattta tagctggtct agccggtgac atgctgactt
6721 ctgctgttgg ttcactgacc tctgcaggag ccaatgccat caatcagaaa ttgaattttg
6781 attacaataa acaactccaa aatgcatcct ttcaacatga taaggaaatg ttgcaggccc
6841 aaattgatgc tacgaagaag ctccaatcag aaatgattgc aattaagcat ggggtcttga
6901 ccgcgggcgg cttttcccca gctgatgcag ccagaggggc agtcaacgcc ccaatgactc
6961 gagtgttgga ttggtcaggg acacgctact acgctccaaa ttctgtgcaa accaccagtt
7021 attccgggca attcaccccc tcgccagtcc atcgggcgca ggtgaagtcc ccttccaatt
7081 catctcagcg ggctgcagct ccaagcagta tccgcagcct gtcaacccaa tcaacttctt
7141 taggctccac ctcctcaggg gggtcctcta caatctcctc tagttcgagg acagcaaact
7201 gggtgcaaca acaaagggct cttagcccgt acatgcaggg agccctgcag acggcatacg
7261 ttacaccgcc gtctagtagg acttccagta tgagctctgt ctcaacagtg cccaaagggg
7321 ttttggactc ctggacacct gtgtttaaca cacgcaggca gccgctgttt gcacacctca
7381 ggaagagggg ggagtcgcag gtttactgaa aaggata
//