Typing tool
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Typing tool
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Complete norovirus genomes
| MK753017 | GII.4 Sydney | |
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| GII.P16 |
ORF1: 1..5054
ORF2: 5035..6657
ORF3: 6657..7463
LOCUS MK753017 7474 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P16-GII.4 Sydney/Lane0371
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK753017
VERSION MK753017.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7474)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7474)
AUTHORS Barclay,L., Cannon,J.L., Tsaknaridis,L.J., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7474
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Lane0371"
/isolate="Hu/US/2017/GII.P16-GII.4 Sydney/Lane0371"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="27-Jun-2017"
/note="genotype: GII.P16-GII.4 Sydney"
gene <1..5054
/gene="ORF1"
CDS <1..5054
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QBS47711.1"
/translation="NNDKEKSSGEGLFTNMSSTLKKALGARPKQPAPRDEPQKPPRPP
TPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQPDVANTAFSVPPLSLR
ENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISMARVELTPLSLYWR
VVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLSRRMVQRTTGFF
RPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIGKIKPLNILNILATCD
WTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPVVMGGIG
LVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAMVRAI
EDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLSTKSASPDIVGTINAL
LARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAREVARKVASTLTGDQRV
GLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADTCPLTLNCDRIENKGK
VFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPDMWKD
AFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERMDEFELQ
GPTITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVKTMEELKQAIRNVTIKR
CRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHHLKHARIRYYVKCVQEA
VYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEEAPKSEDDEFIISSKDI
KEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYE
ELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLITGSEIRKRNPDDFKPK
GKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSLFITSTHVIPAGITE
AFGVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEGTVATVLIKRPTGELMP
LAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGNDYIVI
GVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPGGAPKLSTKTKFWRS
SNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPPRPSVLEAAKQT
IINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFWNGETFTGKLADQASKA
NLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDLSTMVRCARSFGGLMDE
MKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQQRAVLAAALEIMV
RFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCTSQWNSIAHWLLTLCAL
SEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLKEYGLKPTRPDKTEGPL
IISKDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNHEDPNETMIPHSQRP
IQLMALLGEASLHGPSFYSRISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLSTWEG
DRNLAPSFVNEDGVE"
mat_peptide <1..950
/gene="ORF1"
/product="p48"
mat_peptide 951..2048
/gene="ORF1"
/product="NTPase"
mat_peptide 2049..2579
/gene="ORF1"
/product="p22"
mat_peptide 2580..2978
/gene="ORF1"
/product="VPg"
mat_peptide 2979..3521
/gene="ORF1"
/product="Pro"
mat_peptide 3522..5051
/gene="ORF1"
/product="RdRp"
gene 5035..6657
/gene="ORF2"
CDS 5035..6657
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47712.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFETNQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRVV"
gene 6657..7463
/gene="ORF3"
CDS 6657..7463
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47713.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARITTYNAGHFSTPQPSRALPGRTNLRDAVPARGPSNKSS
NSSTATSVYSSQTISTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 acaacaacga caaggaaaaa tcttcaggtg aaggcttatt cacaaatatg tcttccacct
61 taaagaaagc cctcggggct aggcccaaac agcctgcccc gagagacgaa ccacaaaagc
121 ccccaaggcc accaaccccc gagttggtca agaggatacc ccctcctcca cctaatggcg
181 aagaagaaga agaaccagtc attaggtatg aggttaagag tgggatctct ggcctgcccg
241 agctcacaac agtcccccaa ccggacgtgg ccaacacggc attcagtgtt ccaccactga
301 gtttgagaga aaacagggag gccaaggaac cgctaacagg ggcaatatta gagatgtggg
361 acggagagat ataccactat ggcctgtacg tggagaaagg cttagtgttg ggtgtgcaca
421 aaccacctgc agccataagc atggcaagag tggagctgac gccgctgtca ttgtactggc
481 gtgtggtgta cactccccaa tacctcatct cccctgaaac tctcaggagg ctcaacggag
541 aggcgttccc ttacaccgct ttcgacaaca actgctacgc cttttgctgc tgggtgttag
601 acctcaacga ctcatggctt agcaggagga tggtgcaaag aacaacgggc ttcttcagac
661 cttatcaaga gtggaacaga aaacccctgc ctaccatgga tgactccaaa ataaagaagg
721 tagcaaatat attcctatgt tcattgtcca cattattcac cagacccata aaagacctca
781 taggaaaaat taaaccatta aacatattga acatcctggc aacgtgtgac tggacgtttg
841 ccggaatagt ggagtctctg atattacttg ctgaactctt cggagttttc tggacacccc
901 cagatgtgtc tgctatgatc gctcccttac tcggggacta cgagttgcaa gggccagaag
961 acctcgccgt tgaactcgtg cctgtggtaa tgggagggat tggcttggtg ttgggattca
1021 ccaaagagaa aattggcaaa atgttgtcct cagcagcatc aacactcagg gcttgcaaag
1081 atcttggtgc ttatggctta gagatactca aattggtcat gaagtggttc ttcccaaaga
1141 aagaagaggc caatgagcta gccatggtga gggccataga ggatgccgta ctagatcttg
1201 aggcaataga aaataaccac atgacaaccc tgttgaaaga caaagacagc ttagcaacat
1261 acatgaaaac actggacatg gaggaggaga aagccagaag gttgtccaca aaatctgcat
1321 cccctgacat agttgggaca atcaacgccc tgctggctcg aatagcagcg gccaggtcat
1381 tagtccacag ggccaaggaa gagctatcta gcaggataag accagtagtt gttatgatat
1441 ctggcaaacc aggaataggc aaaactcatc tggccaggga ggtagcaaga aaggtggcat
1501 ccactctcac aggggatcag agagtcggac tcataccaag aaacggtgtg gaccattggg
1561 atgcgtacaa aggtgagaga gtcgtgctgt gggacgacta tggcatgagt aaccccatcc
1621 atgatgctct tcgcatacaa gaattggctg atacgtgtcc ccttacctta aattgtgaca
1681 gaattgaaaa taagggaaaa gtttttgaca gtgaagtcat aataattaca acaaaccttg
1741 ccaacccagc cccacttgat tatgtcaact ttgaggcctg ttccaggaga atcgatttcc
1801 tggtgtacgc tgaggcacca gaagtagaaa aggcaaaacg ggactttcct ggtcagccag
1861 atatgtggaa agacgccttc aagccggact tttcacacat caagctacag cttgcacctc
1921 agggcggttt tgacaagaat ggtaacaccc cacatgggaa aggagtgatg aagaccctca
1981 ctaccggttc tctgattgcc cgtgcatcag gcctactgca tgagaggatg gatgaatttg
2041 aactccaagg tcccacaatc accaccttca atttcgaccg gaacagaatc acagcattca
2101 gacaattggc tgcagaaaac aagtatggat tggtggacac catgaaagtt ggcaatcaat
2161 taaaaggagt gaaaaccatg gaagaactca aacaagcaat caggaatgta accatcaaga
2221 ggtgccggat catctacggt ggctccacgt atgaccttga atctgatggc aagggtaaag
2281 ttttggtgga aaaggtcaag aacacctctg tgcagaccaa caacgagttg gccggggccc
2341 tgcaccatct caaacatgct cgaatcaggt actatgtcaa atgtgtgcaa gaagcagtct
2401 attccatcat acaaattgcc ggcgctgcgt ttgtcaccac gcgcattgca cgccgcatga
2461 acatacaaga actctggtcg aagccacaat tagatcaaaa cgaatcagag actaaggaag
2521 aggcccccaa gtcagaagat gacgagttca tcatatcttc taaggacatc aaggaggaag
2581 gaaagaaggg caaaaacaaa actggccgtg gcaagaaaca cactgcattc tccagcaagg
2641 gcttgagcga tgaggagtat gacgagtaca agaggataag agaagagaga aatgggaagt
2701 actctataga ggagtatctt caagacagag acaggtacta tgaggagctc gccattgcca
2761 aggccacgga agaagatttc tgtgaagagg aggagatcaa aatccgtcag agaattttcc
2821 gtcccaccag gaaacaaaga aaggaagaga gggccacatt agggctgata acaggttcag
2881 aaatcagaaa aagaaaccct gatgacttca aacccaaagg gaagctgtgg gccgatgaca
2941 acagaagtgt tgactacaat gagaaactgg actttgaggc ccccccaagc atatggtcta
3001 ggattgtgag ctttggttct ggctggggct tctgggtatc accaagcctg ttcataacat
3061 caactcatgt aatccccgca ggcataacag aagcatttgg agtccccatc aaacaaattc
3121 agatccacaa atcaggtgaa ttttgccgat tcagattccc aaaaccaatt agaccagatg
3181 tgacaggaat gatcttggaa gaaggtgcgc ctgaaggcac cgtggcaact gtgctcatca
3241 aacgccccac cggagagctc atgcctcttg cagccagaat gggaacacac gcaaccatga
3301 aaattcaagg ccgcatggtt ggcggacaga tgggtatgtt gctcactgga tcaaatgcta
3361 aaggaatgga tttgggaaca actcctggtg actgtggctg tccttacatc tataaaaggg
3421 gcaatgacta catagtcatt ggggtgcaca ctgcagcagc ccgtggtgga aacaccgtca
3481 tctgtgccac acagggaagt gagggtgagg caactcttga gggtggagat gacaaaggaa
3541 catactgtgg ggcacccatt ctaggccctg ggggtgcacc aaaattgagc accaaaacca
3601 aattttggag gtcatcgaac acgccccttc caccagggac atatgagcct gcctacctcg
3661 gtggccgtga tccgcgtgtt aagggtgggc cctccttgca acaggtaatg agagaccagt
3721 tgaagccatt cactgaaccc aggggcaaac ctccaagacc aagtgtattg gaagcagcca
3781 aacaaaccat tatcaatgtt ctcgaacaaa ccctggaccc tccacaaaaa tggacatacg
3841 cacaggcgtg tgcctcactt gacaaaacca cctccagtgg gcatccccat cacgtccgaa
3901 agaatgagtt ctggaatggt gagaccttca ctggtaaatt ggcagaccaa gcatcaaaag
3961 caaacctaat gtttgaggaa gggaaacaca tgacaccagt gtatacagca gcgctcaagg
4021 acgagttagt caagactgag aaaatctatg gaaagatcaa gaagagactg ctctggggct
4081 ctgacttgtc caccatggtc cggtgtgcta ggtcatttgg tgggctcatg gacgagatga
4141 aggcacactg catatcactc ccagtacgag ttggcatgaa tatgaatgaa gatggcccaa
4201 taatatttga gaaacattcc agatacaaat accactatga tgcagactac tctcgttggg
4261 attcaacaca acagagggca gtactagcag cagccttgga aatcatggtc agattctctg
4321 cagaaccaca attggcacaa atagtcgctg aggatctact ggcccctagt gtagtagatg
4381 taggagactt taaaatcaca ataaatgaag ggctcccgtc tggtgtgcca tgcacttctc
4441 aatggaactc cattgcacac tggctgctaa ctctctgtgc cttgtctgag gtcaccaagc
4501 tgtcccctga cattatacaa gcaaattcca tgttctcatt ttatggtgat gacgagattg
4561 tcagcaccga cataaaattg gaccctgaac agttaaccgc caagttgaag gagtacggcc
4621 tgaaaccaac ccgcccagac aagaccgagg gacccctgat catcagtaaa gatttgaacg
4681 gactcacttt cctccgaagg acggtgactc gtgacccagc tggctggttt ggaaagctgg
4741 accaaagttc aattttgagg cagatgtact ggactagagg accaaatcat gaagacccca
4801 atgagacaat gataccccat tctcaaagac ccatacagct catggcactg cttggtgaag
4861 cctctcttca tggaccctct ttctacagta gaatcagtaa attggtcata actgaactca
4921 aagaaggtgg gatggacttt tacgtgccaa ggcaggaacc catgttcagg tggatgaggt
4981 tttctgactt gagcacgtgg gagggcgatc gcaatctggc tcccagtttt gtgaatgaag
5041 atggcgtcga gtgacgccaa cccatctgat gggtccgcag ccaacctcgt accagaggtc
5101 aacaatgagg ttatggcttt ggagcccgtt gttggtgccg ctattgcggc acctgtagcg
5161 ggccaacaaa atgtgattga cccctggatt agaaataatt ttgtacaagc ccctggtggg
5221 gagtttacag tatcccctag aaacgctcca ggtgaaatac tatggagcgc gcccctaggc
5281 cctgacctaa atccctacct atcccatttg gccagaatgt acaatggtta tgcaggtggt
5341 tttgaagtgc aggtaattct cgcggggaac gcgttcaccg ccgggaagat tatatttgca
5401 gcagtcccac caaactttcc aactgaaggc ttaagtccta gccaggtcac tatgttcccc
5461 catataatag tagatgttag acaattagaa cctgtgctga ttcccttacc cgatgttagg
5521 aataacttct atcattacaa tcagtcaaat gactccacta ttaagttgat agcaatgttg
5581 tatacaccac ttagggctaa taatgctggg gacgatgttt tcacagtttc gtgccgagtt
5641 ctcacgagac catcccccga ttttgatttc atatttttag tgccacccac agttgagtca
5701 agaactaaac cattctctgt cccagtttta actgttgagg agatgaccaa ttcaagattc
5761 cccatccctt tggaaaagtt gttcacaggc cccagcagtg cctttgttgt tcaaccacaa
5821 aacggcaggt gcacaactga tggcgtgctc ctaggcacca cccaactttc tcctgtcaac
5881 atctgcacct tcagagggga tgtcacccat atcacaggta gtcgcaacta cacaatgaat
5941 ttggcttctc aaaattggaa caactatgac ccaacagaag aaatcccagc ccctctagga
6001 actccagatt ttgtggggaa gattcaaggc atgctcaccc aaaccacaag gacagacggt
6061 tcaacacgcg gccacaaagc tacagtgtac actgggagcg ccgactttgc tccaaagctg
6121 ggtagagttc aatttgaaac tgacacagac catgattttg aaactaatca aaacacaaag
6181 ttcaccccag tcggtgtcat ccaagatggt agcaccaccc accgaaacga accccaacag
6241 tgggtgctcc caagttactc aggcagaaat actcacaatg tacatttggc ccccgctgta
6301 gcccccacct ttccgggtga acaacttctc ttcttcagat ccaccatgcc cggatgcagc
6361 gggtacccca acatggattt ggactgtctg ctcccccagg aatgggtgca gtacttctac
6421 caagaggcag ccccagcaca atctgatgtg gctctgctaa ggtttgtgaa tccagacaca
6481 ggtagggttt tgtttgaatg caagcttcac aaatcaggct atgttacagt ggctcacact
6541 ggccaacatg atttggttat cccccccaat ggttacttta ggtttgattc ctgggtcaac
6601 cagttctaca cgcttgcccc catgggaaat ggaacggggc gtagacgtgt agtataatgg
6661 ctggagcttt ctttgctgga ttggcatctg atgtccttgg ctctggactt ggttccctta
6721 tcaatgctgg agctggggcc atcaaccaaa aagttgagtt tgaaaataac agaaaattgc
6781 aacaagcatc cttccaattt agcagcaatc tgcaacaggc ttcctttcaa catgataaag
6841 agatgctcca agcacaaatt gaggccacca aaaagctaca acaggaaatg atgaaagtta
6901 agcaggcaat gctcctagag ggtgggttct ctgagacaga tgcagctcgc ggggcaatta
6961 acgcccctat gacaaaagct ttggactgga gcgggacaag gtactgggct ccagatgcta
7021 ggattacaac atacaatgca ggccactttt ccacccctca accatcgagg gcactgccag
7081 gaagaactaa tcttagggat gctgtccctg ctcggggacc ctccaacaaa tcttctaact
7141 cttctactgc cacctctgtg tactcaagtc aaactatttc aacgagactt ggttctacag
7201 ctggttctgg aaccagtgtc tcgagcctcc cgtcaactgc aaggactagg agctgggttg
7261 aggaccagaa taggaatttg tcacctttca tgaggggggc ccacaacata tcatttgtca
7321 ccccaccatc tagcagatcc tctagccaag gcacagtctc aaccgtgcct aaagagattt
7381 tggactcctg gactggcgct ttcaacacgc gcaggcagcc tctcttcgct cacattcgta
7441 agcgagggga gtcacgggtg taatgtgaaa agac
//