Typing tool
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Typing tool
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Complete norovirus genomes
| MK753016 | GII.2 | |
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| GII.P16 |
ORF1: 4..5103
ORF2: 5084..6712
ORF3: 6712..7491
LOCUS MK753016 7521 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P16-GII.2/Linn0365
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK753016
VERSION MK753016.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7521)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7521)
AUTHORS Barclay,L., Cannon,J.L., Tsaknaridis,L.J., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7521
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Linn0365"
/isolate="Hu/US/2017/GII.P16-GII.2/Linn0365"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="20-Apr-2017"
/note="genotype: GII.P16-GII.2"
gene 4..5103
/gene="ORF1"
CDS 4..5103
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS47708.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGVSGLPELTTVPQ
PDVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
VSMARVELTPLSLYWRVVYTPQYLISPDTLRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLV
GKIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEV
EKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVK
TMEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEE
APKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPAGITEAFGVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMRIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPYHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 4..999
/gene="ORF1"
/product="p48"
mat_peptide 1000..2097
/gene="ORF1"
/product="NTPase"
mat_peptide 2098..2628
/gene="ORF1"
/product="p22"
mat_peptide 2629..3027
/gene="ORF1"
/product="VPg"
mat_peptide 3028..3570
/gene="ORF1"
/product="Pro"
mat_peptide 3571..5100
/gene="ORF1"
/product="RdRp"
gene 5084..6712
/gene="ORF2"
CDS 5084..6712
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47709.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLSLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6712..7491
/gene="ORF3"
CDS 6712..7491
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47710.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFDHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTVSSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 tgaatgaaga tggcgtctaa cgacgctacc gttgccgttg cttgcaacaa caacaacgac
61 aaagaaaaat cttcaggtga aggcttattc acaaatatgt cttccacctt aaagaaagcc
121 ctcggggcta ggcccaaaca gcctgccccg agagacaaac cacaaaagcc cccaagacca
181 ccaactcccg agttggtcaa gaggataccc cctcctccac ctaatggcga agaagaagaa
241 gaaccagtca ttaggtatga ggttaagagt ggggtctctg gcctgcccga gctcacaaca
301 gtcccccaac cggacgtggc caacacagca ttcagtgttc caccactgag cttgagagaa
361 aacagggagg ccaaggaacc gctaacaggg gcaatattag agatgtggga tggagagata
421 taccactatg gcctgtatgt ggagaaaggc ttagtgttgg gtgtgcacaa accacctgca
481 gccgtaagca tggcaagagt ggagctgacg ccgctgtcat tgtactggcg tgtggtgtac
541 actccccaat acctcatctc ccctgacact ctcaggaggc tcaacgggga ggcattccct
601 tacaccgcct ttgacaacaa ctgctatgcc ttttgctgct gggtgttaga cctcaatgac
661 tcatggctta gcaggaggat ggtgcaaaga acaacgggct tctttagacc ttaccaagag
721 tggaacagaa aacccctgcc caccatggat gactccaaaa ttaagaaggt agcaaatata
781 ttcctatgct cattgtccac attattcacc agacccataa aagacctcgt aggaaaaatt
841 aaaccattaa acatattgaa tatcctggca acgtgtgact ggacttttgc cggaatagtg
901 gagtctctga tattacttgc tgaactcttc ggagttttct ggacaccccc agatgtgtct
961 gctatgatcg cccccttact cggggactac gagttgcagg ggccagaaga cctcgccgtt
1021 gaactcgtgc ccgtggtaat gggggggatt ggtttggtgt tgggattcac caaagagaaa
1081 attggcaaaa tgttatcctc agcagcatca acactcaggg cttgcaaaga tcttggtgcc
1141 tatggcttag agatactcaa attggtcatg aagtggttct tcccaaagaa agaggaggcc
1201 aatgagctag ccatggtgag ggccatagag gatgctgtac tagatcttga ggcaatagaa
1261 aataaccaca tgacaaccct gttaaaagac aaagacagct tagcaacata catgaaaaca
1321 ctggacatgg aggaggagaa agccaggagg ttgtccacaa aatctgcatc ccctgacata
1381 gttgggacaa tcaacgccct gctggctcga atagcagcgg ccaggtcatt agtccacagg
1441 gccaaggaag agctatctag caggataaga ccagtagttg ttatgatatc tggcaaacca
1501 ggaataggca aaactcatct ggccagggag gtggcaagaa aggtggcatc cactctcaca
1561 ggggatcaaa gagtcggact cataccaaga aacggtgtgg accattggga tgcatacaaa
1621 ggtgagagag tcgtgctgtg ggacgactat ggcatgagta accccattca tgatgctctt
1681 cgcatacaag aattggctga tacgtgtccc cttaccttaa attgtgacag aattgaaaat
1741 aagggaaaag tttttgacag cgaggtcata ataattacga caaaccttgc caatccagcc
1801 ccacttgatt atgttaactt tgaggcctgt tccaggagaa ttgatttcct ggtgtacgct
1861 gaggcaccag aagtagaaaa ggcaaaacgg gactttcctg gtcagccaga tatgtggaag
1921 gatgccttca agcccgactt ttcacacatc aagctacagc ttgcacccca gggcggcttt
1981 gacaagaatg gcaacacccc acatgggaaa ggagtgatga agaccctcac taccggttct
2041 ctgattgccc gtgcatcagg cctactgcat gagaggatgg atgaatttga actccaaggt
2101 cccacaatca ccaccttcaa tttcgaccgg aacagaatca cagcattcag acaattggct
2161 gcagaaaaca agtatgggtt ggtggatacc atgaaagttg gcaatcaact aaaaggagtg
2221 aaaaccatgg aggaacttaa acaagcaatc aggaatgtga ccatcaagag gtgccggatc
2281 atctacggtg gctccacgta tgaccttgaa tctgatggca agggcaaggt tttggtggaa
2341 aaggtcaaga acacctctgt acagaccaac aacgagttgg ctggggccct gcaccatctc
2401 aaacacgccc gaatcaggta ctatgtcaaa tgtgtgcaag aagcagtcta ttccatcata
2461 caaattgccg gcgctgcgtt tgtcaccacg cgcattgctc gccgcatgaa catacaagaa
2521 ctctggtcga agccacaatt agatcaaaat gaatcagaga ctaaggaaga ggcccccaag
2581 tcagaagatg acgagttcat catatcttct aaggacatca aggaggaagg aaagaagggc
2641 aaaaacaaaa ctggccgtgg caagaaacac actgcattct ccagcaaggg cttgagcgat
2701 gaggagtatg acgagtacaa gaggataaga gaagagagga atgggaagta ctccatagag
2761 gagtatcttc aagacagaga caggtactat gaggagctcg ccattgccaa ggccacggaa
2821 gaagacttct gtgaagaaga ggagatcaaa atccgtcaga gaattttccg tcccaccagg
2881 aaacaaagaa aggaagagag ggccacatta gggctagtaa caggttcaga aatcagaaaa
2941 agaaaccctg atgacttcaa acccaaaggg aagctgtggg ccgatgacaa caggagtgtt
3001 gactacaatg agaaactgga ctttgaggcc cccccaagca tatggtctag gattgtgagc
3061 tttggttctg gctggggctt ctgggtgtca ccaagccttt tcataacatc aactcatgta
3121 atccccgcag gcataacaga agcatttgga gtccccatca aacaaattca gatccacaaa
3181 tcaggtgaat tttgccgatt cagattccca aagccaatta gaccagatgt aacagggatg
3241 atcttggaag aaggtgcgcc tgagggcacc gtggcaactg tgctcatcaa acgccccacc
3301 ggggagctca tgcctcttgc agccagaatg ggaacacacg caaccatgag aattcaaggc
3361 cgcatggttg gcggacagat gggtatgttg ctcactggat caaatgctaa aggaatggat
3421 ttgggaacaa ctcctggtga ctgtggctgc ccttacatct ataaaagagg caatgactat
3481 atagtcattg gggtgcacac tgcagcagcc cgtggtggaa acaccgtcat ctgtgccaca
3541 cagggaagtg agggtgaggc aacccttgag ggtggagatg acaaaggaac atactgtggg
3601 gcacccattc taggccctgg gggtgcacca aaattgagca ccaaaaccaa attttggagg
3661 tcatcgaaca cgccccttcc accagggaca tatgagcctg cctacctcgg tggccgtgat
3721 ccgcgtgtta agggtgggcc ctccctgcag caggtaatga gagaccagtt gaagccattc
3781 actgaaccca ggggcaaacc tccaagacca agtgtattgg aagcagccaa acaaaccatc
3841 atcaatgtcc tcgaacaaac cctggaccct ccacaaaaat ggacatacgc acaggcgtgt
3901 gcctcacttg acaaaaccac ctccagcggg cacccctatc acgtccgaaa gaatgaattc
3961 tggaatggtg agaccttcac tggaaaattg gcagaccaag catcaaaagc aaacctaatg
4021 tttgaggaag ggaaacacat gacaccagtg tacacagcag cactcaagga cgagctagtc
4081 aagactgaga aaatctatgg aaagattaag aagagactgc tctggggctc tgacttgtcc
4141 actatgatac ggtgcgctag gtcatttggt gggctcatgg acgagatgaa ggcacactgc
4201 atatcactcc cagtccgagt tggcatgaat atgaatgaag atggcccaat aatatttgag
4261 aaacattcca gatacaaata ccactatgat gcagactact ctcgttggga ttcaacacaa
4321 cagagggcag tactagcagc agccttggaa attatggtca gattctctgc agaaccacaa
4381 ttggcacaaa tagtcgctga ggatctgctg gcccctagtg tagtagatgt aggagacttt
4441 aaaattacaa taaatgaagg gctcccctcc ggtgtgccat gcacttctca atggaactcc
4501 atcgcacact ggctgctaac tctctgtgcc ttgtctgaag tcaccaaact gtcccctgac
4561 attatacagg caaattccat gttctcattt tacggtgatg acgagattgt cagcaccgac
4621 ataaaattgg accctgaaca gttaaccgcc aaattgaaag agtacggcct gaaaccaacc
4681 cgcccagata aaaccgaggg acccctgatt atcagtgaag atttgaacgg tctcactttc
4741 ctccgaagga cggtgactcg tgacccagct ggctggtttg gaaaattgga ccaaagctca
4801 attttgaggc agatgtactg gactagagga ccaaatcatg aagaccccaa tgagacaatg
4861 ataccccatt ctcaaagacc catacagctc atggcactgc ttggtgaagc ctctcttcac
4921 ggaccctctt tctacagtaa aatcagtaaa ttggtcataa ctgaactcaa agaaggtggg
4981 atggactttt acgtgccaag gcaagaaccc atgttcaggt ggatgaggtt ttctgacttg
5041 agcacgtggg agggcgatcg caatctggct cccaattttg tgaatgaaga tggcgtcgaa
5101 tgacgccgct ccatctactg atggtgcagc cggcctcgtg ccagaaagta acaatgaggt
5161 catggctctt gaacccgtgg ctggtgccgc cttggcagcc ccggtcactg gtcaaacaaa
5221 tattatagac ccttggatta gagcaaattt tgtccaggcc cccaatggtg aatttacagt
5281 ctctccccgt aatgcccctg gtgaagtgct actgagtcta gagttgggtc cagaattaaa
5341 tccttatctg gcacatttag caagaatgta caatgggtat gccggtggga tggaggtgca
5401 ggtcatgttg gctgggaacg cgttcacagc cggcaagttg gtcttcgccg ccgtgccacc
5461 tcacttcccg gttgaaaacc ttagcccaca gcaaatcacc atgttccctc atgtgatcat
5521 agatgtgaga accttggaac ccgttttatt accactccct gatgttagaa ataatttctt
5581 ccattataat cagaaagatg atcccaagat gagaattgtg gctatgcttt acacccccct
5641 caggtctaat ggttcaggtg atgatgtgtt tacagtctcc tgcagagtgt tgactagacc
5701 ttcccctgac tttgacttca catacctggt gccaccaaca gtggagtcta aaacaaaacc
5761 attcaccctc ccaatcctca cacttgggga actttccaat tccaggttcc cagtgtccat
5821 agaccagatg tataccagcc ctaatgaagt tatatcagtg cagtgtcaaa atggtaggtg
5881 cacactggac ggggagctcc aggggacaac acaactccaa gtcagtggca tttgtgcttt
5941 caaaggtgaa gtgaccgccc acttgcatga caatgatcac ctatataatg ttaccatcac
6001 aaacttgaat gggtcccctt ttgatccctc cgaggatatc cctgcccctc tgggtgtgcc
6061 tgacttccag ggaagggttt ttggtatcat ctcccaaaga gacaaacaca atagtcctgg
6121 gcataatgaa ccagcaaaca ggggacacga cgctgtggtt cccacttaca cagcacagta
6181 cactccaaaa ctgggacaaa ttcaaattgg cacatggcag actgacgatc ttacagtcaa
6241 ccaaccagtc aaattcaccc cagttggact caatgacact gaacatttca accaatgggt
6301 ggtccctagg tatgctggtg ccctaaacct taatacaaac cttgcccctt ctgttgctcc
6361 agtatttcca ggagagcgtc tgctcttctt cagatcatac attcccctca agggcggtta
6421 tggaaaccca gccattgatt gcctactacc acaagagtgg gtgcaacact tctatcagga
6481 agcagcccct tcaatgagtg aggtggccct cgtcagatac atcaacccgg acactggtcg
6541 ggcactgttt gaggccaagc tccacagagc tggtttcatg acagtctcga gcaacaccag
6601 tgccccggtg gttgtgcctg ccaacggata cttcagattt gattcttggg tgaaccaatt
6661 ctattctctc gcccccatgg gaactgggaa tgggcgtaga agggttcaat aatggctgga
6721 gcttttgtag ctggtcttgc aggggatgtg ctcagcaatg ggcttagttc attaatcaat
6781 gcaggtgcta atgcaataaa tcagagggca gaatttgatt ttaatcagaa attgcagcaa
6841 aattcttttg atcatgataa ggagatgttg caggctcaga ttcaggcaac taagcagctg
6901 caggcagaca tgatggctat aaaacaaggg gtcttgaccg ctggcggctt ttcccctgct
6961 gatgcagcca gaggtgctgt gaacgcgccc atgacacaag cgctggattg gaatggtaca
7021 aggtattggg caccaaactc catgaggacc acatcttact ctggaaaatt cacatcaacc
7081 gccccagtga ggcaggccga cttccagcac acccaaagcc ggccttcgag tggctcctct
7141 gtgtcttcct ttgccactca gtcttcaagg ccaactctga ccacaaccac tggttcctca
7201 catggcacag tctcatcaaa ttcaactcgc agcacaagcc tctcccaatc aacggtctcc
7261 agagccacat ctaggactgg tgagtgggtt agagatcaaa atagaaattt ggaaccctac
7321 atgcatggtg ccttacagac agcctttgtc accccacctt ccagcagggc atctgacggg
7381 acagtctcaa ccgtcccgaa aggtgttttg gactcctgga cacctgcgtt taacacccgc
7441 aggcagccgc tttttgcaca cctccgtaag aggggggagt cacaagctta gtgaaaaggt
7501 gaaaatttat ttaggatgaa t
//