Typing tool
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Typing tool
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Complete norovirus genomes
| MK753015 | GII.2 | |
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| GII.P2 |
ORF1: 5..5104
ORF2: 5085..6713
ORF3: 6713..7492
LOCUS MK753015 7536 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P2-GII.2/Lane0946, complete
genome.
ACCESSION MK753015
VERSION MK753015.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7536)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7536)
AUTHORS Barclay,L., Cannon,J.L., Tsaknaridis,L.J., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7536
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Lane0946"
/isolate="Hu/US/2016/GII.P2-GII.2/Lane0946"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="08-May-2016"
/note="genotype: GII.P2-GII.2"
gene 5..5104
/gene="ORF1"
CDS 5..5104
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS47705.1"
/translation="MKMASNDASAAAAVNSNNDNTKSSSDGMLNNMAVTLKRALGARP
KQPAPREKPPRPPRPPTPELIKRIPPPPPNDGDEPTVMFSTAGGVSGLPELTTVGQPP
EANTAFSVPPLSQRENRDAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAIS
IAKVELTPLSLYWRPVYTPQYLISPDTLRKLHGELFPYTAFENNCYAFCCWVLDLNDS
WLSRRMISRTTGFFRPYQEWNRKPLPTMDDSKLKKVANIVLCALSSLFTRPIKDIIGK
LKPLNTLNILASCDWTFAGIVESLILLAELFDVFWTPPDVSAMIAPLLGDYELQGPED
IAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKDEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKNSLAAYMKTLDMEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGKPGIGKTHLAREL
AKKIASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLVNPAPLDYVNFEACSRRIDFLVYADAPEVEK
AKRDFPGQPDMWKDAYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTASSLVARA
SGLLHERLDEYELQGPPLSTFNFDRNKIAAFRQLAAENKYGLVDTMRVGNQLRNVTTM
DELKKAIKNIIIRKCQIVYGGNTYTLESDGKGKVVVERVQSASVQINNEIAGAVHHLR
CARIRYYVKCVQEAIYSLLQIAGTVFVTSRIVSRMNIQNLWSRPLSEDADEATIKEGC
PKPRDEEEFIVSSDDIKPEGKKGKNKSGRGKKHTAFSSKGLSDEEYEEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERANLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNERISFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGITEAFGVPIRQVQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEG
TVATILIKRTTGELMPLAARMGTHATMRIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGNAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPQKWTYAQACASLDKTTSSGYPHHVRKNEHW
NGESFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKVYGKIKKRLLWGSDL
ATMVRCARSFGGLMDELKAHCVTLPIRVGMNMNEDGPIVFEKHSRYRYHYDADYSRWD
STQQRAVLAAAMEIMVKFSAEPQLAQIVAEDLLSPSVVDVGDFKVSINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIVQANSLFSFYGDDEIVSTDIKLDPEKLTGKLR
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTKGP
NHEDPFESMIPHSQRPIQLMSLLGEAALHEPSFYSKISKLVISELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSLVNEDGVE"
mat_peptide 5..994
/gene="ORF1"
/product="p48"
mat_peptide 995..2092
/gene="ORF1"
/product="NTPase"
mat_peptide 2093..2629
/gene="ORF1"
/product="p22"
mat_peptide 2630..3028
/gene="ORF1"
/product="VPg"
mat_peptide 3029..3571
/gene="ORF1"
/product="Pro"
mat_peptide 3572..5101
/gene="ORF1"
/product="RdRp"
gene 5085..6713
/gene="ORF2"
CDS 5085..6713
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47706.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPSEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6713..7492
/gene="ORF3"
CDS 6713..7492
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47707.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPSSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTASSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMRGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc tgctgccgct gctgtcaaca gcaacaacga
61 caacacaaaa tcttcaagtg acggaatgct taataacatg gccgtcaccc ttaaacgagc
121 ccttggggcc cggcccaaac agccagcccc gagggaaaaa cccccaagac cccctagacc
181 accaacacca gaattaatca aaagaatccc ccccccacca cctaatgatg gggacgaacc
241 aaccgtgatg tttagcactg caggtggtgt gtctggccta cctgagctca caacagtcgg
301 tcaaccacct gaagctaaca ctgcctttag tgtgcccccc cttagccaaa gggaaaacag
361 ggacgctaag gaaccgttaa ctggggctat tctggaaatg tgggatgggg agatttatca
421 ttatggactg tatgtggaaa aagggcttgt gctaggcgtg cacaagccgc cggctgccat
481 cagcatagcc aaagtggaat taacacccct ctcactgtat tggaggcctg tgtacacgcc
541 tcagtacctc atatctcctg ataccttgag gaaactccac ggtgagttat ttccctatac
601 agcctttgaa aacaactgtt atgccttctg ttgttgggtt ttggacctca acgattcatg
661 gctaagcagg aggatgatta gtaggactac tggcttcttc aggccctacc aagagtggaa
721 caggaagcct ctcccaacta tggatgactc aaaattgaag aaggtcgcaa acatcgttct
781 gtgtgcattg tcatcattgt tcactaggcc cattaaggat ataatcggca aacttaaacc
841 ccttaacacc ctaaatattc tggcctcatg cgattggacc ttcgctggca tagtagaatc
901 actaatcctc ttggctgaac tctttgatgt gttctggaca cccccagatg tgtctgcaat
961 gatcgcaccc ctcctcggcg actatgagct acaaggtccc gaagacatcg ctgtggagct
1021 cgtgcccgtt gtgatgggtg ggataggtct ggtgttggga ttcaccaaag agaaaatagg
1081 caagatgctc tcctctgcag cgtcaaccct gagggcttgc aaagatcttg gagcctatgg
1141 attggagata ctgaaactag tcatgaaatg gtttttccca aagaaggatg aggccaacga
1201 actggctatg gttagagcca ttgaagacgc tgtgttagac ctggaggcta ttgagaacaa
1261 ccatatgacc actctattga aagacaagaa cagccttgca gcatacatga agaccctgga
1321 catggaagag gaaaaagcta ggaagctatc caccaaatca gcctcccctg acattgtggg
1381 cactataaac gccctgctgg ctaggatcgc tgccgcgcgt tccctagttc atagggccaa
1441 ggaggagctc tccagcaggc caagaccggt cgttttgatg atctctggca agccagggat
1501 aggaaagacc cacttggcca gagaactggc aaagaaaatt gcctcgacac tcacaggaga
1561 ccaaagggtt ggtcttatcc cacggaatgg agttgaccat tgggacgcct acaaaggtga
1621 gagagtggtg ctctgggatg actatggaat gagcaacccc atccacgatg cgctgaggct
1681 gcaggaattg gcagacacat gtccattaac tctaaattgt gacaggattg aaaacaaagg
1741 gaaagtcttc gacagcgacg cgatcataat caccaccaat ttggtcaacc ccgcgccgct
1801 ggattatgtc aactttgagg cctgctccag acgtatagac ttccttgtgt atgctgatgc
1861 cccagaagtc gagaaagcaa agcgggactt tcccggtcaa ccggacatgt ggaaagacgc
1921 ctatcgatct gacttctcac acattaaact acaacttgca ccacaaggtg ggtttgacaa
1981 aaatggtaac accccacatg gtaaaggagt gatgaagact ctcactgcca gctcgctggt
2041 cgcacgtgcc tctggtctct tgcacgagag attagatgag tacgagttgc aaggtccgcc
2101 cctctcaacc ttcaactttg accgtaacaa aatcgcagcg ttcagacaac tcgccgctga
2161 aaacaagtac ggtctggtag acacgatgag ggtgggcaac cagctcagaa atgtcacgac
2221 catggatgaa ctcaagaagg ctatcaagaa catcataatc agaaagtgcc agatagtcta
2281 tggtggcaac acttacacgc ttgagtctga cggcaagggc aaggttgtag ttgagagggt
2341 gcagagcgcc agcgtgcaaa tcaacaatga gatcgctggt gcagtacacc atcttagatg
2401 tgccagaata aggtattatg tcaagtgtgt ccaagaggcc atatactcac tcctccagat
2461 tgccggcacg gtgtttgtca cttcacgcat cgtaagccgc atgaacatcc aaaatctgtg
2521 gtctaggcca ctatctgaag atgcagatga agccaccata aaagaggggt gccctaaacc
2581 tagagatgaa gaagaattca tcgtctcctc agatgatatt aagccagagg gcaagaaagg
2641 caaaaacaag agtggccggg gcaagaaaca cacggcattc tcaagtaaag ggctcagtga
2701 tgaggagtac gaagagtata aaagaatcag agaggagaga aatggcaagt actccataga
2761 ggaatatcta caggacagag acaagtacta tgaagaggtg gccattgcca gggcaaccga
2821 agaagacttc tgtgaagaag aagaggttaa gattcgtcag aggatcttca ggccaacaag
2881 aaagcaacgc aaggaagaaa gagccaacct tggcctcgtt accgggtctg agatcaggaa
2941 gagaaaccca gatgacttca aaccaaaagg aaagctatgg gccgacgatg acaggagcgt
3001 cgactacaat gaaagaatca gctttgaggc tccaccaagc atttggtcta gaattgtcaa
3061 ctttggttct ggatgggggt tctgggtgtc acctagcctc ttcataacat caacacacgt
3121 catacctcaa ggcataactg aggcctttgg tgtacccata aggcaggtgc aaatacacaa
3181 atcgggcgag ttctgtcgct tgagattccc aaaacccatc agaacagatg tgtcaggcat
3241 gatactggag gagggagcgc ccgaaggtac tgttgccacc atactcatca aaagaaccac
3301 tggagagctg atgcctctag cagcaagaat gggaacccac gcgaccatga ggatacaagg
3361 gcgcacagtg ggcggccaga tgggaatgtt gctcactggg tccaatgcaa agagcatgga
3421 tcttggcacc acgcccggtg actgtgggtg tccctacatt tacaaaaggg gtaatgatta
3481 catagtcatt ggagttcaca cagcagccgc tcgtggcgga aacactgtca tctgcgccac
3541 acaaggtagt gagggtgagg ctactctcga gggtggtgac aataaaggaa catattgtgg
3601 ggcaccaatc ttgggccccg gaaatgcccc aaaactgagc actaaaacca agttctggag
3661 gtcctctaca acaccactcc cacccggcac gtacgagccg gcatatctgg gaggaaaaga
3721 cccccgagtc aaaggtgggc catctctgca acaagtcatg cgagaccaac tgaagccatt
3781 caccgaaccc cgtggcaagc caccaaaacc aagtgtcctt gaagctgcca aaaagacaat
3841 tatcaatgtg ttagagcaaa caatagatcc cccacagaag tggacgtacg cgcaagcgtg
3901 cgcgtctctt gacaaaacca catctagtgg gtacccccac cacgtgcgca aaaacgagca
3961 ctggaatggg gaatctttca caggaaaatt ggctgatcag gcatcgaagg caaacctaat
4021 gtttgaggag gggaaacaca tgaccccagt ttatacagct gcccttaagg atgagttggt
4081 taaaactgag aaagtgtatg ggaagataaa gaagaggtta ctttggggct ctgacttggc
4141 caccatggtg aggtgtgcgc gctcctttgg cggcttgatg gacgaactca aggcccactg
4201 tgtgacactc ccgataaggg ttggcatgaa tatgaatgaa gatggaccaa tagtctttga
4261 gaaacattcc agatacaggt atcactatga tgcagactac tccaggtggg attcaacaca
4321 gcagagagcc gttctggccg cggccatgga gattatggtc aaattctcag cagaaccaca
4381 attagcccaa atagttgcag aggatctgtt gtcgcccagt gttgttgacg tgggcgactt
4441 caaagtttcc atcaatgaag gattaccatc gggtgtccct tgcacctctc aatggaactc
4501 catcgcacac tggctcctca ccttgtgtgc cctttctgaa gttacagacc tctctcctga
4561 cattgtgcaa gccaactccc tcttctcctt ctatggtgat gatgaaattg tgagtacaga
4621 tatcaaatta gacccagaaa agttgacggg gaagttgaga gaatatggtc tcaaacccac
4681 ccgtcctgac aaaactgagg gccccttgat tattagcgag gatctgaatg gcctgacctt
4741 cctgaggaga actgtcaccc gcgaccctgc aggatggttt ggcaaactgg accaaagctc
4801 catacttagg caattgtatt ggaccaaagg ccctaatcat gaagacccct ttgagtcaat
4861 gattccacat tcccagaggc ccatacaact catgtcactc ttgggtgaag cagcactgca
4921 tgaaccatca ttttacagca agatcagcaa gcttgtgata tctgagttga aagaaggtgg
4981 aatggatttt tacgtgccca ggcaagaacc tatgtttagg tggatgagat tctcggattt
5041 gagcacgtgg gagggcgatc gaaatcttgc tcccagtctt gtgaatgaag atggcgtcga
5101 atgacgccgc tccatctact gatggtgcag ccggcctcgt gccagaaagt aacaatgagg
5161 tcatggctct tgaacccgtg gctggtgccg ccttggcagc cccggtcacc ggtcaaacaa
5221 atattataga cccttggatt agagcaaatt ttgtccaggc ccccaatggt gaatttacag
5281 tctctccccg aaatgcccct ggtgaagtgc tactgaatct agagttgggt ccagaattaa
5341 atccttatct ggcacattta gcaagaatgt acaatgggta tgccggtggg atggaggtgc
5401 aggtcatgtt ggctggtaac gcgttcacag ccggcaagtt ggtcttcgcc gccgtgccac
5461 ctcacttccc ggttgaaaac cttagcccac aacaaatcac catgttccct catgtgatca
5521 tagatgtgag aaccttggaa cctgttttat taccactccc tgatgttagg aataatttct
5581 tccattataa tcagaaagat gatcccaaga tgagaattgt ggctatgctt tatacccccc
5641 tcaggtctaa tggttcaggt gatgatgtgt ttacagtctc ctgcagagtg ttgactagac
5701 cttcccctga ttttgacttt acatacctgg tgccaccaac agtggagtct aaaacaaaac
5761 cattcaccct cccaatcctc acacttgggg aactttccaa ttctaggttc ccagtgtcca
5821 tagaccagat gtacaccagc cctagtgaag ttatatcagt gcagtgtcaa aatggtaggt
5881 gcacattgga cggggagctc caagggacaa cacaactcca agtcagtggc atttgtgctt
5941 tcaaaggtga agtgaccgcc cacttgcatg acaatgatca cctatataat gtcaccatca
6001 caaatttgaa tgggtcccct tttgatccct ccgaggatat ccccgccccc ctgggtgtgc
6061 ctgatttcca gggaagggtc tttggtatca tctcccaaag agacaaacac aatagtcccg
6121 ggcataatga gccagcaaac aggggacacg acgctgtggt ccctacttac acagcacagt
6181 acactccaaa actgggacaa attcaaattg gcacatggca gactgacgac cttacagtca
6241 atcaaccagt caaattcacc ccagttggac tcaatgacac tgaacatttt aaccaatggg
6301 tggtccctag gtatgctggt gccctaaatc tcaacacaaa ccttgcccct tctgttgctc
6361 cagtatttcc aggagagcgc ctgctcttct tcagatcata cattcccctc aagggtggtt
6421 atggaaaccc agccattgat tgcctactac cacaagagtg ggtgcaacac ttctatcagg
6481 aagcagcccc ttcaatgagt gaggtggccc ttgtcagata catcaacccg gatactggtc
6541 gggcactgtt tgaggccaag cttcacagag ctggtttcat gacagtctcg agcaacacca
6601 gtgccccggt ggttgtgcct gccaacggat acttcagatt tgattcttgg gtgaatcaat
6661 tctattctct cgcccccatg ggaactggga atgggcgtag aagggttcaa taatggctgg
6721 agcttttgta gctggtcttg caggggacgt gctcagtaat gggctcagtt cattaatcaa
6781 tgcaggtgct aatgcaataa atcagagggc agaatttgat tttaaccaga aattgcagca
6841 aaattctttt aatcatgaca aggagatgtt gcaggctcag attcaggcaa ctaagcagct
6901 gcaggcagac atgatggcta ttaaacaagg ggtcttgacc gctggcggtt tttcccctgc
6961 tgatgcagcc agaggtgctg tgaacgcgcc catgacacag gcgctggatt ggaatggcac
7021 aagatattgg gcaccaagct ccatgaggac cacatcttat tctggaaaat tcacatcaac
7081 cgccccagtg aggcaggctg actttcagca cacccaaagc cggccttcga gtggttcttc
7141 tgtgtcttcc tttgccactc agtcttcaag gccaactctg accacaacca ctggctcctc
7201 acatggtaca gcctcatcaa attcaactcg cagcacaagc ctctcccaat caacggtctc
7261 cagagctaca tctaggactg gtgagtgggt tagggatcaa aatagaaatt tggaacccta
7321 catgcgtggt gccttacaga cagcctttgt caccccacct tccagcaggg cgtctgacgg
7381 gacagtctca accgtcccga aaggtgtttt ggactcctgg acacctgcgt tcaacacccg
7441 caggcagccg ctttttgcac acctccgtaa gaggggggag tcacaagctt agtgaaaagg
7501 tgaaaatcta tttaggatga attgattcta cctttt
//