Typing tool
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Typing tool
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Complete norovirus genomes
| MK753014 | GII.2 | |
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| GII.P2 |
ORF1: 1..4925
ORF2: 4906..6534
ORF3: 6534..7273
LOCUS MK753014 7273 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P2-GII.2/Marion0945
nonstructural polyprotein (ORF1) gene, partial cds; VP1 (ORF2)
gene, complete cds; and VP2 (ORF3) gene, partial cds.
ACCESSION MK753014
VERSION MK753014.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7273)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7273)
AUTHORS Barclay,L., Cannon,J.L., Tsaknaridis,L.J., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7273
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Marion0945"
/isolate="Hu/US/2016/GII.P2-GII.2/Marion0945"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="15-Apr-2016"
/note="genotype: GII.P2-GII.2"
gene <1..4925
/gene="ORF1"
CDS <1..4925
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QBS47704.1"
/translation="PTPELIKRIPPPPPNDGDEPTVMFSTAGGVSGLPELTTVGQPPE
ANTAFSVPPLSQRENRDAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISI
AKVELTPLSLYWRPVYTPQYLISPDTLRKLHGELFPYTAFENNCYAFCCWVLDLNDSW
LSRRMISRTTGFFRPYQEWNRKPLPTMDDSKLKKVANIVLCALSSLFTRPIKDIIGKL
KPLNILNILASCDWTFAGIVESLILLAELFDVFWTPPDVSAMIAPLLGDYELQGPEDI
AVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPK
KDEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKNSLAAYMKTLDMEEEKARKLSTK
SASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGKPGIGKTHLARELA
KKIASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCP
LTLNCDRIENKGKVFDSDAIIITTNLVNPAPLDYVNFEACSRRIDFLVYADAPEVEKA
KRDFPGQPDMWKDAYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTASSLVARAS
GLLHERLDEYELQGPPLSTFNFDRNKIAAFRQLAAENKYGLVDTMRVGNQLRNVTTMD
ELKKAIKNIIIRKCQIVYGGNTYTLESDGKGKVVVERVQSASVQINNEIAGAVHHLRC
ARIRYYVKCVQEAIYSLLQIAGTVFVTSRIVSRMNIQNLWSRPLSEDADEATIKEGCP
KPRDEEEFIVSSDDIKPEGKKGKNKSGRGKKHTAFSSKGLSDEEYEEYKRIREERNGK
YSIEEYLQDRDKYYEEVAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERANLGLVT
GSEIRKRNPDDFKPKGKLWADDDRSVDYNERISFEAPPSIWSRIVNFGSGWGFWVSPS
LFITSTHVIPQGITEAFGVPIRQVQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEGT
VATILIKRTTGELMPLAARMGTHATMRIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDC
GCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGP
GNAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPR
GKPPKPNVLEAAKKTIINVLEQTIDPPQKWTYAQACASLDKTTSSGYPHHVRKNEHWN
GESFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKVYGKIKKRLLWGSDLA
TMVRCARSFGGLMDELKAHCVTLPIRVGMNMNEDGPIVFEKHSRYRYHYDADYSRWDS
TQQRAVLAAAMEIMVKFSAEPQLAQIVAEDLLSPSVVDVGDFKVSINEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTDLSPDIVQANSLFSFYGDDEIVSTDIKLDPEKLTGKLRE
YGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTKGPN
HEDPFESMIPHSQRPIQLMSLLGEAALHEPSFYSKISKLVISELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPSLVNEDGVE"
mat_peptide <1..815
/gene="ORF1"
/product="p48"
mat_peptide 816..1913
/gene="ORF1"
/product="NTPase"
mat_peptide 1914..2450
/gene="ORF1"
/product="p22"
mat_peptide 2451..2849
/gene="ORF1"
/product="VPg"
mat_peptide 2850..3392
/gene="ORF1"
/product="Pro"
mat_peptide 3393..4922
/gene="ORF1"
/product="RdRp"
gene 4906..6534
/gene="ORF2"
CDS 4906..6534
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47702.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLSLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
LLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6534..>7273
/gene="ORF3"
CDS 6534..>7273
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47703.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPSSMRTTSYSGKFTSTAPVRQADFQHTQSRTSSGSSVSSFATQSSRPTLTTTT
GSSHGTASSNSTRSTNLSQSTVSRATSRTGEWVRDQNRNLEPYMRGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPL"
ORIGIN
1 caccaacacc agaattaatc aaaagaatcc cccccccacc acctaatgat ggggacgaac
61 caaccgtgat gtttagcact gcaggtggtg tgtctggcct acctgagctc acaacagtcg
121 gtcaaccacc tgaagctaac actgccttta gtgtgccccc ccttagccaa agggaaaaca
181 gggacgctaa ggaaccgtta actggggcta ttctggaaat gtgggatggg gagatttatc
241 attatggact gtatgtggaa aaagggcttg tgctaggcgt gcataagccg ccggctgcca
301 tcagcatagc caaagtggaa ttaacacccc tctcactgta ttggaggcct gtgtacacgc
361 ctcagtacct catatctcct gacaccttga ggaaactcca cggtgagtta tttccctata
421 cagcctttga aaacaactgt tatgccttct gttgttgggt tctggacctc aacgattcat
481 ggctaagcag gaggatgatt agtaggacta ctggcttctt caggccctac caagagtgga
541 acaggaagcc tctcccaact atggatgact caaaattgaa gaaggtcgca aacatcgttc
601 tgtgtgcatt gtcatcattg ttcactaggc ccattaagga tataattggc aaacttaaac
661 cccttaacat cctaaatatt ctggcctcat gcgattggac cttcgctggc atagtagaat
721 cactaatcct cttggctgaa ctctttgatg tgttctggac acccccagat gtgtctgcaa
781 tgatcgcacc cctcctcggc gactatgagc tacaaggtcc cgaagacatc gctgtggagc
841 tcgtgcccgt tgtgatgggt gggataggtt tggtgttggg attcaccaaa gagaaaatag
901 gcaagatgct ctcctctgca gcgtcaaccc tgagggcttg caaagatctt ggagcctatg
961 gattggagat actgaaacta gtcatgaaat ggtttttccc aaagaaggat gaggccaacg
1021 aactggctat ggttagagcc attgaagacg ctgtattaga cctggaggct attgagaaca
1081 accatatgac cactctattg aaagacaaga acagccttgc agcatacatg aagaccctgg
1141 acatggaaga ggaaaaagct aggaagctat ccaccaaatc agcctcccct gacattgtgg
1201 gcactataaa cgccctgctg gctaggatcg ctgccgcgcg ttccctagtt catagggcca
1261 aggaggagct ctccagcagg ccaagaccgg tcgttttgat gatctctggc aagccaggga
1321 taggaaagac ccacttggcc agagaactgg caaagaaaat tgcctcgaca ctcacaggag
1381 accaaagggt tggtcttatc ccacggaatg gagttgacca ttgggacgcc tacaaaggtg
1441 agagagtggt gctctgggat gactatggaa tgagcaaccc catccacgat gcgctgaggc
1501 tgcaggaatt ggcagacaca tgtccattaa ctctaaattg tgacaggatt gaaaacaaag
1561 ggaaagtctt cgacagcgac gcgatcataa tcaccaccaa tttggtcaac cccgcgccgc
1621 tggattatgt caactttgag gcctgctcca gacgtataga cttccttgtg tatgctgatg
1681 ccccagaagt cgagaaagca aagcgggact ttcccggtca accggacatg tggaaagacg
1741 cctatcgatc tgacttctca cacattaaac tacaacttgc accacaaggt gggtttgaca
1801 aaaatggtaa caccccacat ggtaaaggag tgatgaagac tctcactgcc agctcactgg
1861 tcgcacgtgc ctctggtctc ttgcacgaga gattagatga gtacgagttg caaggtccgc
1921 ccctctcaac cttcaacttt gaccgtaaca aaatcgcagc gttcagacaa ctcgccgctg
1981 aaaacaagta cggtctggta gacacgatga gggtgggcaa ccagctcaga aatgtcacga
2041 ccatggatga actcaagaag gctatcaaga acatcataat cagaaagtgc cagatagtct
2101 atggtggcaa cacttacacg cttgagtctg acggcaaggg caaggttgta gttgagaggg
2161 tgcagagcgc cagcgtgcaa atcaacaatg agatcgctgg tgcagtacac catcttagat
2221 gtgccagaat aaggtattat gtcaagtgtg tccaagaggc catatactca ctcctccaga
2281 ttgccggcac ggtgtttgtc acttcacgca tcgtaagccg catgaacatc caaaatctgt
2341 ggtctaggcc actatctgaa gatgcagatg aagccaccat aaaagagggg tgccctaaac
2401 ctagggatga agaagaattc atcgtctcct cagatgatat taagccagag ggcaagaaag
2461 gcaaaaacaa gagtggccgg ggcaagaaac acacggcatt ctcaagtaaa gggctcagtg
2521 atgaggagta cgaagagtac aaaagaatca gagaggagag aaatggcaag tactccatag
2581 aggaatacct acaggacaga gacaagtact atgaagaggt ggccattgcc agggcaactg
2641 aagaagactt ctgtgaagaa gaagaggtta agattcgtca gaggatcttc aggccaacaa
2701 gaaagcaacg caaggaagaa agagccaacc ttggcctcgt taccgggtct gagatcagga
2761 agagaaaccc agatgacttc aaaccaaaag gaaagctatg ggccgacgat gacaggagcg
2821 tcgactacaa tgaaagaatc agctttgagg ctccaccaag catttggtct agaattgtca
2881 actttggttc tggatggggg ttctgggtgt cacctagcct cttcataaca tcaacacacg
2941 tcatacctca aggcataact gaggcctttg gtgtacccat aaggcaggtg caaatacaca
3001 aatcgggcga gttctgtcgc ttgagattcc caaaacccat cagaacagat gtgtcaggca
3061 tgatactgga ggagggagcg cctgaaggta ctgttgccac catactcatc aaaagaacca
3121 ctggagagct gatgcctcta gcagcaagaa tgggaaccca cgcgaccatg aggatacaag
3181 ggcgcacagt gggcggccag atgggaatgt tgctcactgg gtccaatgca aagagcatgg
3241 atcttggcac cacgcccggt gactgtgggt gtccctacat ttacaaaagg ggtaatgatt
3301 acatagtcat tggagttcac acagcagccg ctcgtggcgg aaacactgtc atctgcgcca
3361 cacaaggtag tgagggtgag gccactctcg agggtggtga caataaagga acatattgtg
3421 gggcaccaat cttgggcccc ggaaatgccc caaaactgag cactaaaacc aagttctgga
3481 ggtcctctac aacaccactc ccacccggca cgtacgagcc ggcatatctg ggaggaaaag
3541 acccccgagt caagggtggg ccatctctgc aacaagtcat gcgagaccaa ctgaagccat
3601 tcaccgaacc ccgtggcaag ccaccaaaac caaatgtcct tgaagctgcc aaaaagacaa
3661 ttatcaatgt gttagagcaa acaatagacc ccccacagaa gtggacgtac gcgcaagcgt
3721 gcgcgtctct tgacaaaacc acatctagtg ggtaccccca ccacgtgcgc aaaaacgagc
3781 actggaatgg ggaatctttc acaggaaaat tggctgatca ggcatcgaag gcaaacctaa
3841 tgtttgagga ggggaaacac atgaccccag tttatacagc tgcccttaag gatgagttgg
3901 ttaaaactga gaaagtgtat gggaagataa agaagaggtt actttggggc tctgacttgg
3961 ccaccatggt gaggtgtgcg cgctcctttg gcggtttgat ggacgaactc aaggcccact
4021 gtgtgacact cccgataagg gttggcatga atatgaatga agatggacca atagtctttg
4081 agaaacattc cagatacagg tatcactatg atgcagacta ctccaggtgg gattcaacac
4141 agcagagagc cgttctggcc gcggccatgg agattatggt caaattctca gcagaaccac
4201 aattagccca aatagttgca gaggatctgt tgtcgcccag tgttgttgac gtgggcgact
4261 tcaaagtttc catcaatgaa ggattaccat cgggtgtccc ctgcacctct caatggaact
4321 ccatcgcaca ctggctcctc accttgtgtg ccctttctga agttacagac ctctctcctg
4381 acattgtgca agccaactcc ctcttctcct tctatggtga tgatgaaatt gtgagtacag
4441 atatcaaatt agatccagaa aagttgacgg ggaagttgag agaatatggt ctcaaaccca
4501 cccgtcctga caaaactgag ggccccttga ttattagcga ggatctgaat ggcctgacct
4561 tcctgaggag aactgtcacc cgcgaccctg caggatggtt tggcaaactg gaccaaagct
4621 ccatacttag gcaattgtat tggaccaaag gccctaatca tgaagacccc tttgagtcaa
4681 tgattccaca ttcccagagg cccatacaac tcatgtcact cttgggtgaa gcagcactgc
4741 atgaaccatc attttacagc aagatcagca agcttgtgat atctgagttg aaagaaggtg
4801 gaatggattt ttacgtgccc aggcaagaac ctatgtttag gtggatgaga ttctcggatt
4861 tgagcacgtg ggagggcgat cgcaatcttg ctcccagtct tgtgaatgaa gatggcgtcg
4921 aatgacgccg ctccatctac tgatggtgca gccggcctcg tgccagaaag taacaatgag
4981 gtcatggctc ttgaacccgt ggctggtgcc gccttggcag ccccggtcac cggtcaaaca
5041 aatattatag acccttggat tagagcaaat tttgtccagg cccccaatgg tgaatttaca
5101 gtctcccccc gaaatgcccc tggtgaagtg ctactgagtc tagagttggg tccagaatta
5161 aatccttatc tggcacattt agcaagaatg tacaacgggt atgccggtgg gatggaggtg
5221 caggtcatgt tggctgggaa cgcgttcaca gccggcaagt tggtcttcgc cgccgtgcca
5281 cctcacttcc cggttgaaaa ccttagccca caacaaatca ccatgttccc tcatgtgatc
5341 atagatgtga gaaccttgga acctgtttta ttaccactcc ctgatgttag gaataatttc
5401 ttccattata atcagaaaga tgatcccaag atgagaattg tggctatgct ttataccccc
5461 ctcaggtcta atggttcagg tgatgatgtg tttacagtct cctgcagagt gttgactaga
5521 ccttcccctg attttgactt tacatacctg gtgccaccaa cagtggagtc taaaacaaaa
5581 ccattcaccc tcccaatcct cacacttggg gaactttcca attctaggtt cccagtgtcc
5641 atagaccaga tgtacaccag ccctaatgaa gttatatcag tgcagtgtca aaatggtagg
5701 tgcacattgg acggggagct ccaagggaca acactactcc aagtcagtgg catttgtgct
5761 ttcaaaggtg aagtgaccgc ccacttgcat gacaatgatc acctatataa tgttaccatc
5821 acaaatttga atgggtcccc ttttgatccc tccgaggata tccccgcccc cctgggtgtg
5881 cctgatttcc agggaagggt ctttggtatc atctcccaaa gagacaaaca caatagtccc
5941 gggcataatg aaccagcaaa caggggacac gacgctgtgg tccctacata cacagcacag
6001 tacactccaa aactgggaca aattcaaatt ggcacatggc agactgacga ccttacagtc
6061 aatcaaccag tcaaattcac cccagttgga ctcaatgaca ctgaacattt taaccaatgg
6121 gtggtcccta ggtatgctgg tgccctaaat ctcaacacaa accttgcccc ttctgttgct
6181 ccagtatttc caggagagcg cctgctcttc ttcagatcat acattcccct caagggtggt
6241 tatggaaacc cagccattga ttgcctacta ccacaagagt gggtgcaaca cttctatcag
6301 gaagcagccc cttcaatgag tgaggtggcc cttgtcagat acatcaaccc ggatactggt
6361 cgggcactgt ttgaggccaa gcttcacaga gctggtttca tgacagtctc gagcaacacc
6421 agtgccccgg tggttgtgcc tgccaacgga tacttcagat ttgattcttg ggtgaatcaa
6481 ttctattctc tcgcccccat gggaactggg aatgggcgta gaagggttca ataatggctg
6541 gagcttttgt agctggtctt gcaggggacg tgctcagtaa tgggctcagt tcattaatca
6601 atgcaggtgc taatgcaata aatcagaggg cagaatttga ttttaaccag aaattgcagc
6661 aaaattcttt taatcatgac aaggagatgt tgcaggctca gattcaggca actaagcagc
6721 tgcaggcaga catgatggct attaaacaag gggtcttgac cgctggcggt ttttcccctg
6781 ctgatgcagc cagaggtgct gtgaacgcgc ccatgacaca ggcgctggat tggaatggca
6841 caagatattg ggcaccaagc tccatgagga ccacatctta ttctggaaaa ttcacatcaa
6901 ccgccccagt gaggcaggcc gactttcagc acacccaaag ccggacttcg agtggttctt
6961 ctgtgtcttc ctttgccact cagtcttcaa ggccaactct gaccacaacc actggctcct
7021 cacatggtac ggcctcatca aattcaactc gcagcacaaa cctctcccaa tcaacggtct
7081 ccagagctac atctaggact ggtgagtggg ttagggatca aaatagaaat ttggaaccct
7141 acatgcgtgg tgccttgcag acagcctttg tcaccccacc ttccagcaga gcgtctgacg
7201 ggacagtctc aaccgtcccg aaaggtgttt tggactcctg gacacctgcg ttcaacaccc
7261 gcaggcagcc gct
//