Typing tool
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Typing tool
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Complete norovirus genomes
| MK753012 | GII.2 | |
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| GII.P2 |
ORF1: 4..5103
ORF2: 5084..6712
ORF3: 6712..7491
LOCUS MK753012 7505 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P2-GII.2/Douglas0940
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK753012
VERSION MK753012.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7505)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7505)
AUTHORS Barclay,L., Cannon,J.L., Tsaknaridis,L.J., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7505
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Douglas0940"
/isolate="Hu/US/2016/GII.P2-GII.2/Douglas0940"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="09-Mar-2016"
/note="genotype: GII.P2-GII.2"
gene 4..5103
/gene="ORF1"
CDS 4..5103
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS47696.1"
/translation="MKMASNDASAAAAVNSNNDNTKSSSDGMLNNMAVTLKRALGARP
KQPAPREKPPRPPRPPTPELVKRIPPPPPNDGDEPTVMFSTVGGVSGLPELTTVGQPP
EANTAFSVPPLSQRENRDAKEPLTGTILEMWDGEIYHYGLYVEKGLVLGVHKPPAAIS
VAKVELTPLSLYWRPVYTPQYLIPPDTLRKLHGELFPYTAFENNCYAFCCWVLDLNDS
WLSRRMISRTTGFFRPYQEWNRKPLPTMDDSKLKKVANIVLCALSSLFTRPIKDIIGK
LKPLNILNILASCDWTFAGIVESLILLAELFDVFWTPPDVSAMIAPLLGDYELQGPED
IAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKDEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKNSLAAYMKTLDMEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGKPGIGKTHLAREL
AKKIASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLVNPAPLDYVNFEACSRRIDFLVYADAPEVEK
AKRDFPGQPDMWKDAYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTASSLVARA
SGLLHERLDEYELQGPPLSTFNFDRNKIAAFRQLAAENKYGLVDTMRVGNQLRNVTTM
DELKKAIRNIIIRKCQIVYGGNTYTLESDGKGKVVVERVQSTSVQINNEIAGAVHHLR
CARIRYYVKCVQEAIYSLLQIAGTVFVTSRIVSRMNIQNLWSRPLTEEVDEATMKEGC
PKPREEEEFIVSSDDIKPEGKKGKNKSGRGKKHTAFSSKGLSDEEYEEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERANLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNERISFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGITEAFGVPIRQVQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEG
TVATILIKRTTGELMPLAARMGTHATMRIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGNAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPQKWTYAQACASLDKTTSSGFPHHVRKNEHW
NGESFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKVYGKIKKRLLWGSDL
ATMVRCARSFGGLMDELKAHCVTLPIRVGMNMNEDGPIVFEKHSRYRYHYDADYSRWD
STQQRAVLAAAMEIMVKFSAEPQLAQIVAEDLLSPSVVDVGDFKISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIVQANSLFSFYGDDEIVSTDIKLDPEKLTGKLR
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTKGP
NHEDPFESMIPHSQRPIQLMSLLGEAALHEPSFYSKISKLVISELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSLVNEDGVE"
mat_peptide 4..993
/gene="ORF1"
/product="p48"
mat_peptide 994..2091
/gene="ORF1"
/product="NTPase"
mat_peptide 2092..2628
/gene="ORF1"
/product="p22"
mat_peptide 2629..3027
/gene="ORF1"
/product="VPg"
mat_peptide 3028..3570
/gene="ORF1"
/product="Pro"
mat_peptide 3571..5100
/gene="ORF1"
/product="RdRp"
gene 5084..6712
/gene="ORF2"
CDS 5084..6712
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47697.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLSRMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNITITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6712..7491
/gene="ORF3"
CDS 6712..7491
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47698.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLAAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPGSMRTTAYSGRFTSTTPVRQTDLQHTQSRPTSGSSVSSFATQSSRPTLTTTT
GSSLGTASSNSTRSTNLSQSTVSRATSRTSEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 tgaatgaaga tggcgtctaa cgacgcttct gctgccgctg ctgttaacag caacaacgac
61 aacacaaaat cttcaagtga cggaatgctt aacaacatgg ccgtcaccct taaacgagcc
121 cttggggccc ggcccaaaca gccggccccg agggagaaac ccccaaggcc ccctaggcca
181 ccaacaccag aattggtcaa aagaatcccc cccccaccgc ccaatgatgg ggacgaacca
241 accgtgatgt ttagcactgt aggtggcgtg tctggcctac ctgagctcac aacagttggc
301 caaccacctg aagctaacac ggcctttagt gtgcctcccc tcagccaaag ggagaatagg
361 gacgctaagg aaccgttaac tggaaccatt ctggaaatgt gggatgggga gatttatcat
421 tatggactgt atgtggaaaa agggcttgtg ttaggcgtgc acaagccgcc ggctgccatc
481 agcgtagcca aagtggagtt aacacccctc tcactgtact ggagacctgt ttacacgcct
541 cagtacctta tacctcctga caccttgagg aaactccatg gtgaattgtt tccctacaca
601 gcctttgaaa acaactgtta tgccttctgc tgttgggttt tggatcttaa tgattcatgg
661 ttaagcagga ggatgattag taggactact ggctttttca ggccctacca ggagtggaac
721 aggaagcccc tcccgactat ggatgactca aaactgaaga aggtcgcaaa cattgtcctg
781 tgtgcattgt catcattgtt cactagaccc attaaggaca taattggcaa acttaaaccc
841 ctcaacatcc taaatatcct ggcctcatgc gactggacct tcgctggcat agtggagtca
901 ctaatcctct tggctgaact ctttgatgtg ttctggacac ccccagatgt gtctgcaatg
961 atcgcacccc tcctcggtga ctacgagctg caaggccccg aagacatcgc tgtggagctc
1021 gtgcccgttg ttatgggtgg gataggcttg gtgttgggat tcaccaaaga gaaaataggt
1081 aagatgctct cctctgcagc gtcaactctg agggcatgta aggatcttgg agcctacgga
1141 ttggagatct tgaaattagt catgaaatgg tttttcccaa agaaagatga ggccaacgag
1201 ctggctatgg ttagagccat tgaagacgct gtgttagacc tggaggccat tgagaacaac
1261 catatgacca ctctattgaa agacaagaac agtcttgcag cctacatgaa gaccctggac
1321 atggaagagg aaaaagctag gaaattatct accaaatcag catcccctga cattgtgggc
1381 accataaacg ccctactggc taggatcgct gccgcacgtt ccttagttca tagggccaag
1441 gaggagctct ccagtagacc aaggccagtt gttctgatga tctctggcaa accagggata
1501 ggaaagaccc atctggccag agaattggca aagaaaattg catcaacact cacgggagac
1561 caaagggtag gcctcatccc acggaatgga gttgaccatt gggacgccta caaaggtgag
1621 agagtggtgc tctgggatga ctacggtatg agcaacccca tccacgatgc actaaggttg
1681 caggaattgg cagacacatg tccactaact ctgaattgtg acaggattga gaacaagggg
1741 aaagtcttcg acagtgacgc aatcataatc accaccaatc tggtcaatcc cgcgccgctg
1801 gactatgtca actttgaggc ttgctccaga cgtatagact tccttgtgta tgctgatgcc
1861 ccagaagtcg agaaagcaaa gcgggacttc cccggtcaac cggacatgtg gaaggacgcc
1921 tatcgttctg atttctcaca tatcaaattg caacttgcac cacaaggtgg gtttgacaaa
1981 aatggcaaca ccccacatgg taagggagtg atgaagactc tcactgccag ttcactggtt
2041 gctcgtgctt ctggtctctt gcacgagaga ttagatgagt acgagttaca gggtccgccc
2101 ctttcaacct tcaactttga ccgcaacaaa attgcggcgt tcagacaact cgccgctgaa
2161 aataagtatg gtctggtgga cacgatgagg gtgggcaacc agctcaggaa tgtcacgacc
2221 atggatgaac tcaagaaggc tatcagaaac attataatca ggaagtgcca gatagtctat
2281 ggcggcaaca cttacacgct tgagtctgac ggcaagggta aggttgttgt tgagagggtg
2341 cagagcacca gcgtgcaaat caacaatgag atcgctggtg cagtgcatca ccttagatgt
2401 gccaggataa ggtattatgt caagtgtgta caagaggcca tatactcact cctccaaatt
2461 gccggcacgg tgtttgtcac ttcacgcatc gtgagccgca tgaacattca aaacttgtgg
2521 tccagaccat taactgaaga agtagatgag gcaaccatga aagaggggtg ccccaaacct
2581 agggaagaag aggagtttat cgtctcttca gatgacatca agccagaggg taagaaaggt
2641 aagaacaaga gtggccgggg caagaaacac acggcattct caagtaaagg tctcagtgat
2701 gaggagtatg aggagtacaa aagaatcaga gaggagagaa acggcaagta ctccatagag
2761 gaatacctac aggacagaga caaatactat gaagaggtgg ccattgccag ggcaactgaa
2821 gaagacttct gtgaagaaga agaggttaag attcgccaga gaatcttcag gccaacaaga
2881 aagcaacgca aggaagaaag agccaacctt ggcctcgtca ctggatctga gatcaggaag
2941 aggaacccag atgacttcaa accaaaagga aagctgtggg ccgacgatga taggagcgtc
3001 gactacaacg aaagaatcag ctttgaggcc ccaccgagca tttggtccag aattgttaac
3061 tttggttctg gatgggggtt ctgggtgtca cccagtctct tcataacatc aacacatgtc
3121 atacctcaag gcataactga ggcctttggt gtgcccataa ggcaggttca aatacacaag
3181 tcgggcgaat tctgtcgtct gagattccca aaacccatca ggacagatgt gtcaggtatg
3241 atactggagg agggagcgcc tgaaggcact gttgccacca tactcatcaa aagaaccact
3301 ggagagctga tgcctcttgc agcaagaatg ggcacccacg cgaccatgag aatacaagga
3361 cgcacggtgg gcggccagat ggggatgctg cttactgggt ctaacgcaaa aagcatggat
3421 cttggcacca cgcccggcga ctgtgggtgc ccctacattt acaaaagggg caacgactat
3481 atagtcattg gagtccacac agcagccgct cgtggcggaa acactgtcat ctgcgccaca
3541 caaggtagtg agggtgaggc aacactcgag ggtggtgata acaaaggaac atactgtggg
3601 gcaccaatcc taggccccgg gaatgcccca aaactgagca ccaaaactaa gttctggagg
3661 tcctcaacaa caccactccc acccggcacg tacgaaccgg catacctggg aggaaaagac
3721 ccccgagtca aaggtggacc atctctgcaa caagttatgc gagaccaact gaagccattt
3781 actgagcccc gtggtaagcc accaaaacca agtgtccttg aagctgctaa aaagacaatc
3841 atcaatgtgc tagaacaaac aatagatccc ccacaaaagt ggacgtacgc gcaagcgtgc
3901 gcgtctcttg acaaaaccac atctagtgga ttccctcacc acgtgcgcaa gaacgagcac
3961 tggaatgggg aatctttcac aggaaaattg gctgatcagg catcaaaagc aaacttaatg
4021 tttgaagagg ggaagcacat gaccccagtt tacacagctg cccttaagga cgagctggtc
4081 aaaactgaga aagtgtatgg gaaaataaag aagaggttgc tttggggctc tgacctggcc
4141 accatggtgc ggtgcgcgcg ctcctttggt ggtttgatgg acgagctcaa agcccactgt
4201 gtgacacttc caataagggt tggcatgaac atgaatgaag atggaccaat agtctttgag
4261 aaacactcca gatataggta ccactatgat gcagactatt ccaggtggga ctcaacacag
4321 caaagagccg ttctggccgc ggccatggag atcatggtta aattctcagc agaaccacaa
4381 ctagcccaaa tagttgcaga ggatctattg tcgcctagtg tagttgacgt gggcgacttc
4441 aaaatttcca tcaatgaagg gttgccatcg ggtgtccctt gcacctccca gtggaattcc
4501 atcgcacact ggctcctcac tttgtgtgcc ctctctgagg tcacagacct ctctcctgac
4561 attgtacagg ccaactccct cttctccttc tatggagatg atgaaattgt gagcacagat
4621 attaaattag acccagaaaa actaacgggg aagttgagag aatatggtct caaacctact
4681 cgtcctgaca aaactgaggg ccccctaatc atcagtgagg atctgaatgg cctgactttc
4741 ctgaggagaa ccgtcacccg tgaccctgca gggtggtttg gcaaactgga ccaaagctcc
4801 atacttagac aattgtattg gaccaagggc cccaatcatg aagacccctt tgagtcaatg
4861 atcccacact cccaaagacc catacaactc atgtcactct tgggtgaggc ggcactgcat
4921 gaaccatcat tctacagcaa gattagcaag cttgtgatat ctgaattgaa agaaggtgga
4981 atggattttt acgtgcccag gcaagaacct atgttcaggt ggatgagatt ctcggatttg
5041 agcacgtggg agggcgatcg caatcttgct cccagtcttg tgaatgaaga tggcgtcgaa
5101 tgacgccgct ccatctactg atggtgcagc cggcctcgtg ccagaaagta ataatgaggt
5161 catggctctt gaacccgtgg ctggtgccgc tttggcagcc ccagtcactg gtcaaacaaa
5221 tattatagac ccttggatta gagcaaattt tgtccaggcc cccaatggtg aattcacagt
5281 ctccccccgt aatgcccctg gtgaagtgct actaaatctg gagttgggtc cggaattaaa
5341 tccttatctg gcacacttat caagaatgta caacgggtat gccggtggaa tggaggtgca
5401 ggtcatgttg gctgggaacg cgttcacagc cggcaagttg gtcttcgccg ccgtgccacc
5461 ccacttcccg gttgaaaacc ttagcccaca acaaattacc atgttccctc atgtgattat
5521 agatgtaagg actttggaac ctgttttatt accactccct gatgttagaa ataatttctt
5581 ccattacaat cagaaagatg atcccaagat gagaattgtg gctatgcttt atacccccct
5641 tagatctaat ggctcaggtg acgatgtgtt cacagtctcc tgtagggtgt tgactagacc
5701 ctcccctgac tttgatttca cgtatctggt gccaccaaca gtggagtcta aaacaaaacc
5761 attcaccctc ccaatcctca cacttgggga actttccaat tctagattcc cagtgtctat
5821 agaccagatg tacaccagtc ctaatgaagt tatatcagtg cagtgtcaaa atggtaggtg
5881 cacattggac ggggagctcc aagggacaac acaactccag gtcagtggta tttgtgcttt
5941 caagggagaa gtgaccgccc acttgcatga caatgatcac ctatacaata tcaccatcac
6001 aaatctgaat ggatcccctt ttgacccctc tgaggacatc cctgcccctt tgggcgtgcc
6061 tgactttcag ggaagggtct ttggtatcat ctcccaaaga gacaaacaca atagccctgg
6121 acataatgaa ccagcaaaca ggggacacga tgctgtggtc cctacttaca cagcacagta
6181 tactccaaaa ctgggtcaaa ttcaaattgg cacatggcag actgacgatc ttactgtcaa
6241 ccaaccagta aaattcaccc cagttggact caatgatact gaacatttta accaatgggt
6301 ggttccccga tatgctggtg ccctaaatct caacacaaac cttgcccctt ctgttgcccc
6361 agtatttcca ggggagcgcc ttctcttttt cagatcatac atccccctca agggtggcta
6421 tggaaaccca gccattgatt gtctactacc acaagagtgg gtacaacatt tctatcagga
6481 agctgcccct tcaatgagtg aggtggccct tgtcaggtac atcaacccag acactggccg
6541 ggcactgttt gaggccaagc tccacagagc tggtttcatg acggtctcga gcaacaccag
6601 tgccccggtg gtcgtgcctg ccaatggata cttcagattt gactcttggg tgaaccagtt
6661 ttattctctc gcccccatgg gaactgggaa tgggcgtaga agggttcaat aatggctgga
6721 gcttttgtag ctggtcttgc aggggacgtg ctcagcaatg ggctcagttc actaatcaat
6781 gcaggcgcta atgcaataaa tcagagggca gaatttgatt ttaaccagaa attacagcaa
6841 aattctttta atcatgataa ggagatgcta caggctcaaa ttcaggcaac caagcagctg
6901 caagcagaca tgatggctat aaagcagggg gtcctggccg ctggcggctt ttcccctgct
6961 gatgcagcca gaggtgctgt gaatgcgccc atgacacagg cgctggattg gaatggcaca
7021 aggtattggg caccaggctc catgaggacc acagcctact ctgggagatt cacatcaacc
7081 accccagtga ggcagaccga ccttcagcac acccaaagcc ggcctacgag tggctcttct
7141 gtatcctcct ttgccactca gtcttcaagg ccgactttga ccacaaccac tgggtcctca
7201 cttggcacag cttcatcaaa ttcgactcgc agtactaacc tctcccaatc aacagtctcc
7261 agagctacat ctaggactag tgagtgggtt agagaccaaa atagaaattt ggaaccctac
7321 atgcatggtg ccttacagac agcctttgtc accccacctt ccagcagggc gtctgacggg
7381 acagtctcaa ccgtcccgaa aggtgttttg gactcctgga cacctgcgtt caacacccgc
7441 aggcagccgc tctttgcaca cctccgtaag aggggggagt cacaagctta gtgaaaaggt
7501 gaaaa
//