Typing tool
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Typing tool
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Complete norovirus genomes
| MK753011 | GII.2 | |
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| GII.P2 |
ORF1: 1..4932
ORF2: 4913..6541
ORF3: 6541..7292
LOCUS MK753011 7292 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2015/GII.P2-GII.2/Yamhill0931
nonstructural polyprotein (ORF1) gene, partial cds; VP1 (ORF2)
gene, complete cds; and VP2 (ORF3) gene, partial cds.
ACCESSION MK753011
VERSION MK753011.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7292)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7292)
AUTHORS Barclay,L., Cannon,J.L., Tsaknaridis,L.J., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7292
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Yamhill0931"
/isolate="Hu/US/2015/GII.P2-GII.2/Yamhill0931"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="30-Dec-2015"
/note="genotype: GII.P2-GII.2"
gene <1..4932
/gene="ORF1"
CDS <1..4932
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS47695.1"
/translation="PRPPTPELIKRIPPPPPNDGDEPTVMFSTADGVSGLPELTTVGQ
PPEANTAFSVPPLSQRENRDAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
ISIAKVELTPLSLYWRPVYTPQYLISPDTLRKLHGELFPYTAFENNCYAFCCWVLDLN
DSWLSRRMISRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIVLCALSSLFTRPIKDII
GKLKPLNILNILASCDWTFAGIVESLILLAELFDVFWTPPDVSAMIAPLLGDYELQGP
EDIAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKDEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKNSLAAYMKTLDMEEEKARKL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGKPGIGKTHLAR
ELAKKIASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELAD
TCPLTLNCDRIENKGKVFDSDAIIITTNLVNPAPLDYVNFEACSRRIDFLVYADAPEV
EKAKRDFPGQPDMWKDAYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTASSLVA
RASGLLHERLDEYELQGPPLSTFNFDRNKIAAFRQLAAENKYGLVDTMRVGNQLRNVT
TMDELKKAIKNIIIRKCQIVYGGNTYTLESDGKGKVVVERVQSASVQINNEIAGAVHH
LRCARIRYYVKCVQEAIYSLLQIAGTVFVTSRIVSRMNIQNLWSRPLSEDADEATIKE
GCPKPRDEEEFIVSSDDIKPEGKKGKNKSGRGKKHTAFSSKGLSDEEYEEYKRIREER
NGKYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERANLG
LVTGSEIRKRNPDDFKPKGKLWADDDRSVDYNERISFEAPPSIWSRIVNFGSGWGFWV
SPSLFITSTHVIPQGITEAFGVPIRQVQIHKSGEFCRLRFPKPIRTDVSGMILEEGAP
EGTVATILIKRTTGELMPLAARMGTHATMRIQGRTVGGQMGMLLTGSNAKSMDLGTTP
GDCGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPI
LGPGNAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFT
EPRGKPPKPSVLEAAKKTIINVLEQTIDPPQKWTYAQACASLDKTTSSGYPHHVRKNE
HWNGESFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKVYGKIKKRLLWGS
DLATMVRCARSFGGLMDELKAHCVTLPIRVGMNMNEDGPIVFEKHSRYRYHYDADYSR
WDSTQQRAVLAAAMEIMVKFSAEPQLAQIVAEDLLSPSVVDVGDFKVSINEGLPSGVP
CTSQWNSIAHWLLTLCALSEVTDLSPDIVQANSLFSFYGDDEIVSTDIKLDPEKLTGK
LREYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTK
GPNHEDPFESMIPHSQRPIQLMSLLGEAALHEPSFYSKISKLVISELKEGGMDFYVPR
QEPMFRWMRFSDLSTWEGDRNLAPSLVNEDGVE"
mat_peptide <1..822
/gene="ORF1"
/product="p48"
mat_peptide 823..1920
/gene="ORF1"
/product="NTPase"
mat_peptide 1921..2457
/gene="ORF1"
/product="p22"
mat_peptide 2458..2856
/gene="ORF1"
/product="VPg"
mat_peptide 2857..3399
/gene="ORF1"
/product="Pro"
mat_peptide 3400..4929
/gene="ORF1"
/product="RdRp"
gene 4913..6541
/gene="ORF2"
CDS 4913..6541
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47693.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHAIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAILYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6541..>7292
/gene="ORF3"
CDS 6541..>7292
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47694.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPSSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTASSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMRGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAQP"
ORIGIN
1 cctagaccac caacaccaga attaatcaaa agaatccccc ccccaccacc taatgatggg
61 gacgaaccaa ccgtgatgtt tagcactgca gatggtgtgt ctggcctacc tgagctcaca
121 acagtcggtc aaccacctga agctaacact gcctttagtg tgccccccct tagccaaagg
181 gaaaacaggg acgctaagga accgttaact ggggctattc tggaaatgtg ggatggggag
241 atttatcatt atggactgta tgtggaaaaa gggcttgtgc taggcgtgca caagccgccg
301 gctgccatca gcatagccaa agtggaatta acacccctct cactgtattg gaggcctgtg
361 tacacgcctc agtacctcat atctcctgac accttgagga aactccacgg tgagttattt
421 ccctatacag cctttgaaaa caactgttat gccttctgtt gttgggtttt ggacctcaac
481 gattcatggc taagcaggag gatgattagt aggactactg gcttctttag gccctaccaa
541 gattggaaca ggaagcctct cccaactatg gatgactcaa aattgaagaa ggtcgcaaac
601 attgttctgt gtgcattgtc atcattgttc actaggccca ttaaggatat aattggcaaa
661 cttaaacccc ttaacatcct aaatattctg gcctcatgcg attggacctt cgctggcata
721 gtagaatcac taatcctctt ggctgaactc tttgatgtgt tctggacacc cccagatgtg
781 tctgcaatga tcgcacccct cctcggcgac tatgagctac aaggtcccga agacatcgct
841 gtggagctcg tgcccgttgt gatgggtggg ataggtctgg tgttgggatt caccaaagag
901 aaaataggca agatgctctc ctctgcagcg tcaaccctga gggcttgcaa agatcttgga
961 gcctatggat tggagatact gaaactagtc atgaaatggt ttttcccaaa gaaggatgag
1021 gccaacgaac tggctatggt tagagccatt gaagacgctg tattagacct ggaggctatt
1081 gagaacaacc atatgaccac tctattgaaa gacaagaaca gccttgcagc atacatgaag
1141 accctggaca tggaagagga aaaagctagg aagctatcca ccaaatcagc ctcccctgac
1201 attgtgggca ctataaacgc cctgctggct aggatcgctg ccgcgcgttc cctagttcat
1261 agggccaagg aggagctctc cagcaggcca agaccggtcg ttttgatgat ctctggcaag
1321 ccagggatag gaaagaccca cttggccaga gaactggcaa agaaaattgc ctcgacactc
1381 acaggagacc aaagggttgg tcttatccca cggaatggag ttgaccattg ggacgcctac
1441 aaaggtgaga gagtggtgct ctgggatgac tatggaatga gcaaccccat ccacgatgcg
1501 ctgaggctgc aggaattggc agacacatgt ccattaactc taaattgtga caggattgaa
1561 aacaaaggga aagtcttcga cagcgacgcg atcataatca ccaccaattt ggtcaacccc
1621 gcgccgctgg attatgtcaa ctttgaggcc tgctccagac gtatagactt ccttgtgtat
1681 gctgatgccc cagaagtcga gaaagcaaag cgggactttc ccggtcaacc ggacatgtgg
1741 aaagacgcct atcgatctga cttctcacac attaaactac aacttgcacc acaaggtggg
1801 tttgacaaaa atggtaacac cccacatggt aaaggagtga tgaagactct cactgccagc
1861 tcactggtcg cacgtgcctc tggtctcttg cacgagagat tagatgagta cgagttgcaa
1921 ggtccgcccc tctcaacctt caactttgac cgtaacaaaa tcgcagcgtt cagacaactc
1981 gccgctgaaa acaagtacgg tctggtagac acgatgaggg tgggcaacca gctcagaaat
2041 gtcacgacca tggatgaact caagaaggct atcaagaaca tcataatcag aaagtgccag
2101 atagtctatg gtggcaacac ttacacgctt gagtctgacg gcaagggcaa ggttgtagtt
2161 gagagggtgc agagcgccag cgtgcaaatc aacaatgaga tcgctggtgc agtacaccat
2221 cttagatgtg ccagaataag gtattatgtc aagtgtgtcc aagaggccat atactcactc
2281 ctccagattg ccggcacggt gtttgtcact tcacgcatcg taagccgcat gaacatccaa
2341 aatctgtggt ctaggccact atctgaagat gcagatgaag ccaccataaa agaggggtgc
2401 cctaaaccta gggatgaaga agaattcatc gtctcctcag atgatattaa gccagagggc
2461 aagaaaggca aaaacaagag tggccggggc aagaaacaca cggcattctc aagtaaaggg
2521 ctcagtgatg aggagtacga agagtacaaa agaatcagag aggagagaaa tggcaagtac
2581 tccatagagg aatacctaca ggacagagac aagtactatg aagaggtggc cattgccagg
2641 gcaactgaag aagacttctg tgaagaagaa gaggttaaga ttcgtcagag gatcttcagg
2701 ccaacaagaa agcaacgcaa ggaagaaaga gccaaccttg gcctcgttac cgggtctgag
2761 atcaggaaga gaaacccaga tgacttcaaa ccaaaaggaa agctatgggc cgacgatgac
2821 aggagcgtcg actacaatga aagaatcagc tttgaggctc caccaagcat ttggtctaga
2881 attgtcaact ttggttctgg atgggggttc tgggtgtcac ctagcctctt cataacatca
2941 acacacgtca tacctcaagg cataactgag gcctttggtg tacccataag gcaggtgcaa
3001 atacacaaat cgggcgagtt ctgtcgcttg agattcccaa aacccatcag aacagatgtg
3061 tcaggcatga tactggagga gggagcgccc gaaggtactg ttgccaccat actcatcaaa
3121 agaaccactg gagagctgat gcctctagca gcaagaatgg gaacccacgc gaccatgagg
3181 atacaagggc gcacagtggg cggccagatg ggaatgttgc tcactgggtc caatgcaaag
3241 agcatggatc ttggcaccac gcccggtgac tgtgggtgtc cctacattta caaaaggggt
3301 aatgattaca tagtcattgg agttcacaca gcagccgctc gtggcggaaa cactgtcatc
3361 tgcgccacac aaggtagtga gggtgaggct actctcgagg gtggtgacaa taaaggaaca
3421 tattgtgggg caccaatctt gggccccgga aacgccccaa aactgagcac taaaaccaag
3481 ttctggaggt cctctacaac accactccca cccggcacgt acgagccggc atatctggga
3541 ggaaaagacc cccgagtcaa aggtgggcca tctctgcaac aagtcatgcg agaccaactg
3601 aagccattca ccgaaccccg tggcaagcca ccaaaaccaa gtgtccttga agctgccaaa
3661 aagacaatta tcaatgtgtt agagcaaaca atagaccccc cacagaagtg gacgtacgcg
3721 caagcgtgcg cgtctcttga caaaaccaca tctagtgggt acccccacca cgtgcgcaaa
3781 aacgagcact ggaatgggga atctttcaca ggaaaattgg ctgatcaggc atcgaaggca
3841 aacctaatgt ttgaggaggg gaaacacatg accccagttt atacagctgc ccttaaggat
3901 gagttggtta aaactgagaa agtgtatggg aagataaaga agaggttact ttggggctct
3961 gacttggcca ccatggtgag gtgtgcgcgc tcctttggcg gtttgatgga cgaactcaag
4021 gcccactgtg tgacactccc gataagggtt ggcatgaata tgaatgaaga tggaccaata
4081 gtctttgaga aacattccag atacaggtat cactatgatg cagactactc caggtgggat
4141 tcaacacagc agagagccgt tctggccgcg gccatggaga ttatggtcaa attctcagca
4201 gaaccacaat tagcccaaat agttgcagag gatctgttgt cgcccagtgt tgttgacgtg
4261 ggcgacttca aagtttccat caatgaagga ttaccatcgg gtgtcccttg cacctctcaa
4321 tggaactcca tcgcacactg gctcctcacc ttgtgtgccc tttctgaagt tacagatctc
4381 tctcctgaca ttgtgcaagc caactccctc ttctccttct atggtgatga tgaaattgtg
4441 agtacagata tcaaattaga cccagaaaag ttgacgggga agttgagaga atatggtctc
4501 aaacccaccc gtcctgacaa aactgagggc cccttgatta ttagcgagga tctgaatggc
4561 ctgaccttcc tgaggagaac tgtcacccgc gaccctgcag gatggtttgg caaactggac
4621 caaagctcca tacttaggca attgtattgg accaaaggcc ctaatcatga agaccccttt
4681 gagtcaatga ttccacattc ccagaggccc atacaactca tgtcactctt gggtgaagca
4741 gcactgcatg aaccatcatt ttacagcaag atcagcaagc ttgtgatatc tgagttgaaa
4801 gaaggtggaa tggattttta cgtgcccagg caagaaccta tgtttaggtg gatgagattc
4861 tcggatttga gcacgtggga gggcgatcgc aatcttgctc ccagtcttgt gaatgaagat
4921 ggcgtcgaat gacgccgctc catctactga tggtgcagcc ggcctcgtgc cagaaagtaa
4981 caatgaggtc atggctcttg aacccgtggc tggtgccgcc ttggcagccc cggtcaccgg
5041 tcaaacaaat attatagacc cttggattag agcaaatttt gtccaggccc ccaatggtga
5101 atttacagtc tctccccgaa atgcccctgg tgaagtgcta ctgaatctag agttgggtcc
5161 agaattaaat ccttatctgg cacatttagc aagaatgtac aatgggtatg ccggtgggat
5221 ggaggtgcag gtcatgttgg ctgggaacgc gttcacagcc ggcaagttgg tcttcgccgc
5281 cgtgccacct cacttcccgg ttgaaaacct tagcccacaa caaatcacca tgttccctca
5341 tgcgatcata gatgtgagaa ccttggaacc tgttttatta ccactccctg atgttaggaa
5401 taatttcttc cattataatc agaaagatga tcccaagatg agaattgtgg ctatacttta
5461 tacccccctc aggtctaatg gttcaggtga tgatgtgttt acagtctcct gcagagtgtt
5521 gactagacct tcccctgatt ttgactttac atacctggtg ccaccaacag tggagtctaa
5581 aacaaaacca ttcaccctcc caatcctcac acttggggaa ctttccaatt ctaggttccc
5641 agtgtccata gaccagatgt acaccagccc taatgaagtt atatcagtgc agtgtcaaaa
5701 tggtaggtgc acattggacg gggagctcca agggacaaca caactccaag tcagtggcat
5761 ttgtgctttc aaaggtgaag tgaccgccca cttgcatgac aatgatcacc tatataatgt
5821 taccatcaca aatttgaatg ggtccccttt tgatccctcc gaggatatcc ccgcccccct
5881 gggtgtgcct gatttccagg gaagggtctt tggtatcatc tcccaaagag acaaacacaa
5941 tagtcccggg cataatgaac cagcaaacag gggacacgac gctgtggtcc ctacttacac
6001 agcacagtac actccaaaac tgggacaaat tcaaattggc acatggcaga ctgacgacct
6061 tacagtcaat caaccagtca aattcacccc agttggactc aatgacactg aacattttaa
6121 ccaatgggtg gtccctaggt atgctggtgc cctaaatctc aacacaaacc ttgccccttc
6181 tgttgctcca gtgtttccag gagagcgcct gctcttcttc agatcataca ttcccctcaa
6241 gggtggttat ggaaacccag ccattgattg cctactacca caagagtggg tgcaacactt
6301 ctatcaggaa gcagcccctt caatgagtga ggtggccctt gtcagataca tcaacccgga
6361 tactggtcgg gcactgtttg aggccaagct tcacagagct ggtttcatga cagtctcgag
6421 caacaccagt gccccggtgg ttgtgcctgc caacggatac ttcagatttg attcttgggt
6481 gaatcaattc tattctctcg cccccatggg aactgggaat gggcgtagaa gggttcaata
6541 atggctggag cttttgtagc tggtcttgca ggggacgtgc tcagtaatgg gctcagttca
6601 ttaatcaatg caggtgctaa tgcaataaat cagagggcag aatttgattt taaccagaaa
6661 ttgcagcaaa attcttttaa tcatgataag gagatgttgc aggctcagat tcaggcaact
6721 aagcagctgc aggcagacat gatggctatt aaacaagggg tcttgaccgc tggcggtttt
6781 tcccctgctg atgcagccag aggtgctgtg aacgcgccca tgacacaggc gctggattgg
6841 aatggcacaa gatattgggc accaagctcc atgaggacca catcttattc tggaaaattc
6901 acatcaaccg ccccagtgag gcaggccgac tttcagcaca cccaaagccg gccttcgagt
6961 ggttcttctg tgtcttcctt tgccactcag tcttcaaggc caactctgac cacaaccact
7021 ggctcctcac atggtacagc ctcatcaaat tcaactcgca gcacaagcct ctcccagtca
7081 acggtctcca gagctacatc taggactggt gagtgggtta gggatcaaaa tagaaatttg
7141 gaaccctaca tgcgtggtgc cttacagaca gcctttgtca ccccaccttc cagcagggcg
7201 tctgacggga cagtctcaac cgtcccgaaa ggtgttttgg actcctggac acctgcgttc
7261 aacacccgca ggcagccgct ttttgcacag cc
//