Typing tool
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Typing tool
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Complete norovirus genomes
| MK753010 | GII.13 | |
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| GII.P16 |
ORF1: 4..5100
ORF2: 5081..6709
ORF3: 6709..7440
LOCUS MK753010 7457 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2014/GII.P16-GII.13/Marion0901
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK753010
VERSION MK753010.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7457)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7457)
AUTHORS Barclay,L., Cannon,J.L., Tsaknaridis,L.J., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7457
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Marion0901"
/isolate="Hu/US/2014/GII.P16-GII.13/Marion0901"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="07-Jan-2014"
/note="genotype: GII.P16-GII.13"
gene 4..5100
/gene="ORF1"
CDS 4..5100
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS47690.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDNSQKPPRPPTPELVKRMPPPPPNGEEEEPVIRYEVKSGISGLPELTTVPQP
DVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAI
SMAKVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLND
SWLSRRMVQRTTGFFRPYQEWNRKPLPTVDDSKIKKVANIFLCSLSTLFTRPIKDLMG
KIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPE
DLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFF
PKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLS
TKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLARE
VARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADT
CPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVE
KAKRDFPGQPDMWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIAR
ASGLLHERMDEFELQGPTVTTFNFDRNRIAAFRQLAAENKYGLVDTMRVGNQLKGVKT
MEELKQAIKNVTIKRCRIIYGGSTYDLESDGKGRVLVEKVKNTSVQTNNELAGALHHL
KHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIVRRMNIQELWSKPPLDQNESEAKEEA
PKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGK
YSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERVTLGLVT
GSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPS
LFITSTHVIPAGITEAFGVPIKQIQVHKSGEFCRFRFPKPIRSDVTGMILEEGAPEGT
VATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDC
GCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGP
GGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPR
GKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFWN
GETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTDKVYGKIKKRLLWGSDLS
TMIRCARSFGGLMDEMKAHCITLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDS
TQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKISINEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTKLSPDIVQANSMFSFYGDDEIVSTDIKLDPEKLTTKLKE
YGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPN
HEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 4..996
/gene="ORF1"
/product="p48"
mat_peptide 997..2094
/gene="ORF1"
/product="NTPase"
mat_peptide 2095..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3024
/gene="ORF1"
/product="VPg"
mat_peptide 3025..3567
/gene="ORF1"
/product="Pro"
mat_peptide 3568..5097
/gene="ORF1"
/product="RdRp"
gene 5081..6709
/gene="ORF2"
CDS 5081..6709
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47691.1"
/translation="MKMASNDAAPSNDGAASLVPEAINETMPLEPVAGASIAAPVAGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAIPPNFPVDMISPAQITMLPHLIVDVRTLEPIMIPLPD
VRNVFYHFNNQPQPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFIYLVPP
SVESKTKPFTLPILTISELTNSRFPIPIEQLYTAPNENNVVQCQNGRCTLDGELQGTT
QLLSSAVCSYRGRTVANSGDNWDQNLLQLTYPSGASYDPTDEVPAPLGTQDFSGMLYG
VLTQDNVSEGTGEAKNAKGVYISTTSGRFTPKIGTIGLHSITENVHPNQQSRFTPVGV
AQNENTPFQQWVLPHYAGALALNTNLAPAVAPTFPGEQLLFFRSRVPCVQGLRGQDAF
IDCLLPQEWVNHFYQEAAPSQADVALIRYVNPDTGRTLFEAKLHRSGFITVSHTGTYP
LVVPPNGHFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6709..7440
/gene="ORF3"
CDS 6709..7440
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47692.1"
/translation="MAGAFIAGLAGDMLTSAVGSLTSAGANAINQKLNFDYNKQLQNA
SFQHDKEMLQAQIDATKKLQSEMIAIKHGVLTAGGFSPADAARGAVNAPMTRVLDWSG
TRYYAPNSVQTTSYSGQFTPSPVHRAQVKSPSNSSQRTAAPSSIRSLSTQSTSLGSTS
SGGSSTISSSSRTANWVQQQRALSPYMQGALQTAYVTPPSSRTSSMSSVSTVPKGVLD
SWTPVFNTRRQPLFAHLRKRGESQV"
ORIGIN
1 tgaatgaaga tggcgtctaa cgacgctacc gttgccgttg cttgcaacaa caacaacgac
61 aaggaaaaat cttcaggtga aggcttattc acaaacatgt cttccacctt aaagaaagcc
121 ctcggggccc ggcccaaaca gcctgccccg agggacaact cacaaaagcc cccaagacca
181 ccaactcccg agttggttaa gaggatgcct cctcccccac ctaacggaga agaggaagaa
241 ccagtcatta ggtatgaggt taagagtgga atctctggcc tgcccgagct cacaacagtc
301 cctcaaccgg atgtggccaa cacggcattc agtgtcccac cgctgagctt gagagaaaac
361 agggaggcca aggaaccgct gacaggggca atattagaga tgtgggatgg agagatatac
421 cactatggcc tgtacgtgga gaaaggctta gtgttgggtg tgcacaaacc acctgcagct
481 ataagcatgg caaaagtgga gctgacgccg ttgtcattgt actggcgtgt ggtctacacc
541 ccccaatacc tcatctcccc tgaaactctc aggaggctca acggagaggc attcccctac
601 actgcctttg acaacaactg ctatgccttt tgctgttggg tattagacct caatgactca
661 tggcttagca ggaggatggt gcaaagaaca acaggcttct tcagacctta ccaagagtgg
721 aacagaaaac ccctgcccac tgtggatgac tccaaaatca agaaggtggc aaacatattc
781 ctgtgctcac tgtccacgtt gttcaccaga cctataaaag acctcatggg aaaaattaag
841 ccattaaaca tcttgaacat cctggcaacg tgtgactgga cattcgccgg aatagtggag
901 tctcttatat tacttgctga actctttgga gttttctgga cacccccaga cgtgtctgct
961 atgatcgctc ctttacttgg agactacgag ttgcaagggc cagaagacct tgccgttgag
1021 ctcgtacctg tagtaatggg agggattggt ttggtgttgg gattcaccaa agagaaaatt
1081 ggaaaaatgt tgtcctcagc agcatcaacg ctcagggctt gtaaagatct tggtgcctat
1141 ggcttagaga tactcaaact ggtcatgaag tggttcttcc caaagaaaga agaggccaat
1201 gagctagcca tggtgagagc tatagaggat gctgtactag atcttgaggc aatagaaaat
1261 aatcacatga caactctgtt gaaagacaaa gacagcctag caacctacat gaaaacacta
1321 gacatggagg aggaaaaggc cagaagattg tccacaaaat ctgcatcccc tgacatagtt
1381 gggacgatca acgccctgct ggctcgaata gcagcggcta ggtcactagt ccacagggcc
1441 aaggaggagt tatctagcag gataagacca gtggttgtta tgatatctgg caaaccaggg
1501 ataggcaaaa ctcatttggc cagggaagtg gcaagaaagg tggcatccac tctcacaggg
1561 gatcaaagag tcgggctcat accgagaaac ggtgtggacc attgggatgc atacaaaggt
1621 gagagagtcg tgctgtggga cgactatggc atgagcaacc ccattcatga tgctctgcgc
1681 atacaagaat tggctgacac gtgtcccctc accttaaatt gtgacagaat tgaaaataag
1741 ggaaaagttt ttgacagtga agtcataata atcacaacaa accttgccaa tccagctcca
1801 cttgattatg tcaactttga ggcctgttcc aggagaattg acttcctggt gtacgccgag
1861 gcaccagaag tagaaaaggc aaaacgagac tttcctggtc aaccagatat gtggaaggac
1921 gccttcaagt cggacttttc acatatcaag ctgcaacttg cacctcaggg cggctttgac
1981 aagaatggca acaccccaca tgggaaagga gtgatgaaga ccctcaccac cggttcactg
2041 atcgcccgtg catcaggctt actgcatgag aggatggatg aatttgaact ccaaggcccc
2101 acagtcacca cctttaattt tgaccggaac agaatcgctg cattcagaca attggctgca
2161 gaaaacaagt atggattggt ggacaccatg agagttggca atcaattaaa aggggtgaaa
2221 accatggaag aactcaaaca agcaatcaag aatgtgacca tcaagaggtg ccggatcatc
2281 tacggcggct ccacgtatga ccttgaatct gatggtaagg gcagagttct ggtggaaaag
2341 gtcaagaaca cctctgtaca gaccaacaac gagttggccg gagccctgca tcacctcaaa
2401 catgcccgaa tcaggtacta tgtcaaatgt gtgcaagaag cagtctactc tattatacaa
2461 atcgccggcg ctgcgtttgt caccacacgc atagtacgcc gcatgaacat acaagagctt
2521 tggtcgaagc caccattaga tcaaaatgaa tcagaggcta aggaagaggc ccccaagtca
2581 gaagatgacg agttcatcat atcttctaag gacatcaagg aggaaggaaa gaagggcaaa
2641 aacaaaactg gccgtggcaa gaaacatact gcattctcta gcaagggctt gagcgatgag
2701 gagtacgacg agtacaagag gataagagaa gagagaaatg ggaagtactc tatagaggag
2761 tatcttcaag acagagacag gtactatgag gaactcgcca tcgccaaggc cacggaagaa
2821 gacttctgtg aggaggagga gatcaaaatc cgtcagagga tcttccgtcc caccaggaag
2881 caaaggaagg aagagagggt cacactaggg ctagtaactg gttcagaaat cagaaaaaga
2941 aaccctgatg acttcaaacc taaagggaaa ctgtgggctg atgacaacag aagtgttgac
3001 tacaatgaga aactggactt tgaggccccc ccaagcatat ggtctaggat tgtgagtttt
3061 ggttctggtt ggggtttctg ggtgtcacca agcctgttca taacatcaac tcacgtaatc
3121 cctgcaggca taacagaggc atttggtgtc cccatcaaac aaatccaggt ccacaaatca
3181 ggtgaatttt gccggttcag attcccaaaa ccaattagat cagatgtgac aggaatgatc
3241 ttggaagaag gtgcgcctga gggcaccgtg gcaaccgtgc tcatcaaacg ccctaccgga
3301 gagctcatgc cccttgcagc cagaatggga acacacgcaa ccatgaaaat tcagggccgc
3361 atggttggcg gacagatggg tatgttgctc actggttcaa atgctaaagg aatggattta
3421 ggaacaactc ctggtgattg tggctgtccc tacatctaca aaaggggcaa tgactatata
3481 gtcattgggg tgcacacagc agcagcccgt ggtggaaaca ccgtcatctg tgccacacag
3541 ggaagtgagg gtgaggcaac ccttgagggt ggagatgaca aaggaacata ctgtggggca
3601 cccattctag gccccggggg ggcaccaaaa ttgagcacca aaaccaaatt ttggaggtca
3661 tcgaacacgc ctcttccacc agggacgtat gagcctgcct acctcggtgg ccgtgacccg
3721 cgtgttaagg gtgggccctc cttgcagcag gtaatgagag accagttgaa gccattcacc
3781 gagcccaggg gtaaacctcc aagaccaagt gtgttggaag cagccaaaca aaccatcatc
3841 aacgtcctcg aacaaactct ggaccctcca caaaaatgga catacgcaca ggcgtgtgct
3901 tcacttgaca aaaccacctc cagcgggcac ccccaccatg tccgaaagaa tgaattctgg
3961 aatggtgaga ccttcactgg taaattggca gaccaagcat caaaagcaaa tctaatgttt
4021 gaggaaggga aacacatgac accagtgtat acagcagccc tcaaggatga gctggtcaag
4081 actgacaaag tctatggaaa gatcaagaag agactgctct ggggctctga cttgtccacc
4141 atgatccggt gcgccaggtc ctttggtggg ctcatggatg agatgaaagc acactgcata
4201 acactcccag tccgagttgg catgaacatg aatgaagatg gtccaataat atttgagaag
4261 cactccagat acaagtatca ctatgatgca gattactccc gctgggattc aacacaacag
4321 agggcagtgc tagcagcagc cttggagatc atggtcaggt tctctgcaga gccacaattg
4381 gcacaaatag tcgctgagga tctgctggcc cccagtgtgg tagatgtagg agactttaaa
4441 atttcaataa atgaagggct cccctctggt gtaccatgca cttctcaatg gaattccatc
4501 gcacactggc tgctaaccct ctgcgccttg tctgaagtca ccaaactgtc ccctgacatt
4561 gtacaggcaa actccatgtt ctcattttac ggtgatgacg agattgtcag caccgatata
4621 aaattggacc ctgaaaagtt aaccaccaaa ttgaaggagt acggcctgaa accaactcgc
4681 ccagacaaaa ccgagggacc cctgatcatc agtgaggatt tgaacggact cactttcctc
4741 cggagaacgg tgactcgtga cccagctggc tggtttggaa aattggacca aagctcaata
4801 ttgaggcaga tgtactggac tagaggacca aatcatgaag accccaacga gacaatgata
4861 ccccactctc aaagacccat acagctcatg gcactgcttg gtgaggcctc ccttcacgga
4921 ccctctttct acagcaaaat tagtaagttg gtcataactg aactcaaaga aggtgggatg
4981 gatttttacg tgccaaggca ggaacccatg ttcaggtgga tgaggttttc tgacttgagc
5041 acgtgggagg gcgatcgcaa tctggctccc aattttgtga atgaagatgg cgtcgaatga
5101 cgccgctcca tcgaatgatg gtgcagctag tctcgtacca gaggccatta atgagactat
5161 gccattggaa cccgttgctg gcgcatctat tgctgcccca gtggcgggac aaactaacat
5221 aattgacccc tggataagaa caaattttgt gcaagcccct aatggagagt tcacagtatc
5281 accgagaaat tcccctggag agattctatt aaatttagag ttaggaccag atttgaatcc
5341 ttatttggcc catctgtcaa ggatgtacaa tggatatgct ggaggtgttg aggtgcaagt
5401 gcttcttgct gggaacgcgt tcacagcagg aaagatatta tttgcagcaa tcccacccaa
5461 ctttcctgta gatatgatta gcccagctca aattactatg cttccccatt tgattgtaga
5521 tgttaggaca ttggaaccta ttatgatacc cttaccagat gttaggaatg tgttctatca
5581 ttttaacaat caaccccaac ctaggatgag attagtggct atgctctata ccccattgag
5641 atctaatggt tcaggagatg atgtctttac tgtgtcttgt agagtgttga ctaggccaac
5701 ccctgacttt gaattcattt acctagtgcc tccctctgta gagtccaaaa ctaaaccatt
5761 cacacttcca atattgacca tttctgaact aaccaactcc cggtttccca tcccaattga
5821 gcaactgtac acggccccaa atgagaataa tgttgtacag tgtcaaaatg gaaggtgcac
5881 cttggatgga gagcttcagg gcaccaccca gctgctatca agtgcagttt gctcttacag
5941 gggtaggact gtggctaaca gtggggacaa ttgggaccag aatttgctcc agctgaccta
6001 cccaagcggt gcaagctatg accccactga tgaagtacca gcacccttgg gcacccagga
6061 tttcagtggg atgttgtatg gggtgttaac ccaagacaat gtaagtgagg gtacagggga
6121 ggccaaaaat gctaagggag tatacatatc caccaccagt ggaagattca ccccaaaaat
6181 tggaacaatt ggattgcatt caataactga aaatgtgcac cccaatcagc aatcacggtt
6241 cacccccgtt ggagttgctc agaatgaaaa tacccccttc cagcaatggg ttctaccaca
6301 ctacgcaggt gctcttgctc taaacaccaa tttggcaccc gctgttgccc cgactttccc
6361 tggcgagcaa ttactgttct tcaggtcccg tgttccatgt gttcaaggtc tgcgggggca
6421 ggatgctttc atagattgtc tcctacctca agagtgggtg aaccattttt atcaagaggc
6481 tgctccctcc caagcagacg ttgccctcat caggtatgtc aaccctgata ctggtcgcac
6541 gctgtttgag gctaaattgc acaggtcagg tttcattact gtgtcacaca ctggtaccta
6601 cccccttgtg gtccccccaa atggtcattt caggtttgat tcttgggtta accaattcta
6661 ctcactcgcc cccatgggaa ctggcaatgg gcgtagaaga gttcaataat ggcaggagca
6721 tttatagctg gtctagccgg tgacatgctg acttctgctg ttggttcact gacctctgca
6781 ggagccaatg ccatcaatca gaaattgaat tttgattaca ataaacaact ccaaaatgca
6841 tcctttcaac atgataagga aatgttgcag gcccaaattg atgctacgaa gaagctccaa
6901 tcagaaatga ttgcaattaa gcatggggtt ttgaccgcgg gcggcttttc cccagctgat
6961 gcagccagag gggcagtcaa cgccccaatg actcgagtgt tggattggtc agggacacgc
7021 tactacgctc caaattctgt gcaaaccacc agttattccg ggcaattcac cccctcgcca
7081 gtccatcggg cgcaggtgaa gtccccttcc aattcatctc agcggactgc agctccaagc
7141 agtatccgca gcctgtcaac ccaatcaact tctttaggct ccacctcctc aggggggtcc
7201 tctacaatct cctctagttc gaggacagca aactgggtgc aacaacaaag ggctcttagc
7261 ccgtacatgc agggagccct gcagacggca tacgtcacac cgccgtctag taggacttcc
7321 agtatgagct ctgtctcaac agtgcccaaa ggggttttgg actcctggac acctgtgttt
7381 aacacacgca ggcagccgct gtttgcacac ctcaggaaga ggggggagtc acaggtttag
7441 tgaaaaggat aatcaac
//