Typing tool
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Typing tool
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Complete norovirus genomes
| MK753008 | GII.13 | |
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| GII.P16 |
ORF1: 3..5099
ORF2: 5080..6708
ORF3: 6708..7439
LOCUS MK753008 7456 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2013/GII.P16-GII.13/Multnomah0890
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK753008
VERSION MK753008.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7456)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7456)
AUTHORS Barclay,L., Cannon,J.L., Tsaknaridis,L.J., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7456
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Multnomah0890"
/isolate="Hu/US/2013/GII.P16-GII.13/Multnomah0890"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="04-Dec-2013"
/note="genotype: GII.P16-GII.13"
gene 3..5099
/gene="ORF1"
CDS 3..5099
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS47684.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDNSQKPPRPPTPELIKRMPPPPPNGEEEEPVIRYEVKSGISGLPELTTVPQP
DVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAI
SMAKVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLND
SWLSRRMVQRTTGFFRPYQEWNRKPLPTVDDSKIKKVANIFLCSLSTLFTRPIKDLMG
KIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPE
DLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFF
PKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLS
TKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLARE
VARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADT
CPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVE
KAKRDFPGQPDMWKGAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIAR
ASGLLHERMDEFELQGPTVTTFNFDRNRIAAFRQLAAENKYGLVDTMRVGNQLKGVKT
MEELKQAIKNVTIKRCRIIYGGSTYDLESDGKGRVLVEKVKNTSVQTNNELAGALHHL
KHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIVRRMNIQELWSKPPLDQNESEAKEEA
PKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGK
YSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERVTLGLVT
GSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPS
LFITSTHVIPAGITEAFGVPIKQIQVHKSGEFCRFRFPKPIRSDVTGMILEEGAPEGT
VATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDC
GCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGP
GGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPR
GKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFWN
GETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTDKVYGKIKKRLLWGSDLS
TMIRCARSFGGLMDEMKAHCITLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDS
TQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKISINEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTKLSPDIVQANSMFSFYGDDEIVSTDIKLDPEKLTTKLKE
YGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPN
HEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 3..995
/gene="ORF1"
/product="p48"
mat_peptide 996..2093
/gene="ORF1"
/product="NTPase"
mat_peptide 2094..2624
/gene="ORF1"
/product="p22"
mat_peptide 2625..3023
/gene="ORF1"
/product="VPg"
mat_peptide 3024..3566
/gene="ORF1"
/product="Pro"
mat_peptide 3567..5096
/gene="ORF1"
/product="RdRp"
gene 5080..6708
/gene="ORF2"
CDS 5080..6708
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47685.1"
/translation="MKMASNDAAPSNDGAASLVPEAINETMPLEPVAGASIAAPVAGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAIPPNFPVDMISPAQITMLPHLIVDVRTLEPIMIPLPD
VRNVFYHFNNQPQPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFIYLVPP
SVESKTKPFTLPILTISELTNSRFPIPIEQLYTAPNENNVVQCQNGRCTLDGELQGTT
QLLSSAVCSYRGRTVANSGDNWDQNLLQLTYPSGASYDPTDEVPAPLGTQDFSGMLYG
VLTQDNVSEGTGEAKNAKGVYISTTSGRFTPKIGTIGLHSITENVHPNQQSRFTPVGV
AQNENTPFQQWVLPHYAGALALNTNLAPAVAPTFPGEQLLFFRSRVPCVQGLRGQDAF
IDCLLPQEWVNHFYQEAAPSQADVALIRYVNPDTGRTLFEAKLHRSGFITVSHTGTYP
LVVPPNGHFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6708..7439
/gene="ORF3"
CDS 6708..7439
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47686.1"
/translation="MAGAFIAGLAGDMLTSAVGSLTSAGANAINQKLNFDYNKQLQNA
SFQHDKEMLQAQIDATKKLQSEMIAIKHGVLTAGGFSPADAARGAVNAPMTRVLDWSG
TRYYAPNSVQTTSYSGQFTPSPVHRAQVKSPSNSSQRTAAPSSIRSLSTQSTSLGSTS
SGGSSTISSSSRTANWVQQQRALSPYMQGALQTAYVTPPSSRASSMSSVSTVPKGVLD
SWTPVFNTRRQPLFAHLRKRGESQV"
ORIGIN
1 gaatgaagat ggcgtctaac gacgctaccg ttgccgttgc ttgcaacaac aacaacgaca
61 aggaaaaatc ttcaggtgaa ggcttattca caaacatgtc ttccacctta aagaaagccc
121 tcggggcccg gcccaaacag cctgccccga gggacaactc acaaaagccc ccaagaccac
181 caactcccga gttgattaag aggatgcctc ctcccccacc taacggagaa gaggaagaac
241 cagtcattag gtatgaggtt aagagtggaa tctctggcct gcccgagctc acaacagtcc
301 ctcaaccgga tgtggccaac acggcattca gtgtcccacc gctgagcttg agagaaaaca
361 gggaggccaa ggaaccgctg acaggggcaa tattagagat gtgggatgga gagatatacc
421 actatggcct gtacgtggag aaaggcttag tgttgggtgt gcacaaacca cctgcagcta
481 taagcatggc aaaagtggag ctgacgccgt tgtcattgta ctggcgtgtg gtctacaccc
541 cccaatacct catctcccct gaaactctca ggaggctcaa cggagaggca ttcccctaca
601 ctgcctttga caacaactgc tatgcctttt gctgttgggt attagacctc aatgactcat
661 ggcttagcag gaggatggtg caaagaacaa caggcttctt cagaccttac caagagtgga
721 acagaaaacc cctgcccact gtggatgact ccaaaatcaa gaaggtggca aacatattcc
781 tgtgctcact gtccacgttg ttcaccagac ctataaaaga cctcatggga aaaattaagc
841 cattaaacat cttgaacatc ctggcaacgt gtgactggac attcgccgga atagtggagt
901 ctcttatatt acttgctgaa ctctttggag ttttctggac acccccagat gtgtctgcta
961 tgatcgctcc tttacttgga gactacgagt tgcaagggcc agaagacctt gccgttgagc
1021 tcgtacctgt agtaatggga gggattggtt tggtgttggg attcaccaaa gagaaaattg
1081 gaaaaatgtt gtcctcagca gcatcaacgc tcagggcttg taaagatctt ggtgcctatg
1141 gcttagagat actcaaactg gtcatgaagt ggttcttccc aaagaaagaa gaggccaatg
1201 agctagccat ggtgagagct atagaggatg ctgtactaga tcttgaggca atagaaaata
1261 atcacatgac aactctgttg aaagacaaag acagcctagc aacctacatg aaaacactag
1321 acatggagga ggaaaaggcc agaagattgt ccacaaaatc tgcatcccct gacatagttg
1381 ggacgatcaa cgccctgctg gctcgaatag cagcggctag gtcactagtc cacagggcca
1441 aggaggagtt atctagcagg ataagaccag tggttgttat gatatctggc aaaccaggga
1501 taggcaaaac tcatttggcc agggaagtgg caagaaaggt ggcatccact ctcacagggg
1561 atcaaagagt cgggctcata ccgagaaacg gtgtggacca ttgggatgca tacaaaggtg
1621 agagagtcgt gctgtgggac gactatggca tgagcaaccc cattcatgat gctctgcgca
1681 tacaagaatt ggctgacacg tgtcccctta ccttaaattg tgacagaatt gaaaataagg
1741 gaaaagtttt tgacagtgaa gtcataataa tcacaacaaa ccttgccaat ccagctccac
1801 ttgattatgt caactttgag gcctgttcca ggagaattga cttcctggtg tacgccgagg
1861 caccagaagt agaaaaggca aaacgagact ttcctggtca accagatatg tggaagggcg
1921 ccttcaagtc ggacttttca catatcaagc tgcaacttgc acctcagggc ggctttgaca
1981 agaatggcaa caccccacat gggaaaggag tgatgaagac cctcaccacc ggttcactga
2041 tcgcccgtgc atcaggctta ctgcatgaga ggatggatga atttgaactc caaggcccca
2101 cagtcaccac ctttaatttt gaccggaaca gaatcgctgc attcagacaa ttggctgcag
2161 aaaacaagta tggattggtg gacaccatga gagttggcaa tcaattaaaa ggggtgaaaa
2221 ccatggaaga actcaaacaa gcaatcaaga atgtgaccat caagaggtgc cggatcatct
2281 acggcggctc cacgtatgac cttgaatctg atggtaaggg cagagttctg gtggaaaagg
2341 tcaagaacac ctctgtacag accaacaacg agttggccgg agccctgcat cacctcaaac
2401 atgcccgaat caggtactat gtcaaatgtg tgcaagaagc agtctactct attatacaaa
2461 tcgccggcgc tgcgtttgtc accacacgca tagtacgccg catgaacata caagagcttt
2521 ggtcgaagcc accattagat caaaatgaat cagaggctaa ggaagaggcc cccaagtcag
2581 aagatgacga gttcatcata tcttctaagg acatcaagga ggaaggaaag aagggcaaaa
2641 acaaaactgg ccgtggcaag aaacatactg cattctctag caagggcttg agcgatgagg
2701 agtacgacga gtacaagagg ataagagaag agagaaatgg gaagtactct atagaggagt
2761 atcttcaaga cagagacagg tactatgagg aactcgccat cgccaaggcc acggaagaag
2821 acttctgtga ggaggaggag atcaaaatcc gtcagaggat cttccgtccc accaggaagc
2881 aaaggaagga agagagggtc acactagggc tagtaactgg ttcagaaatc agaaaaagaa
2941 accctgatga cttcaaacct aaagggaaac tgtgggctga tgacaacaga agtgttgact
3001 acaatgagaa actggacttt gaggcccccc caagcatatg gtctaggatt gtgagttttg
3061 gttctggttg gggtttctgg gtgtcaccaa gcctgttcat aacatcaact cacgtaatcc
3121 ctgcaggcat aacagaggca tttggtgtcc ccatcaaaca aatccaggtc cacaaatcag
3181 gtgaattttg ccggttcaga ttcccaaaac caattagatc agatgtgaca ggaatgatct
3241 tggaagaagg tgcgcctgag ggcaccgtgg caaccgtgct catcaaacgc cctaccggag
3301 agctcatgcc ccttgcagcc agaatgggaa cacacgcaac catgaaaatt cagggccgca
3361 tggttggcgg acagatgggt atgttgctca ctggttcaaa tgctaaagga atggatttag
3421 gaacaactcc tggtgattgt ggctgtccct acatctacaa aaggggcaat gactatatag
3481 tcattggggt gcacacagca gcagcccgtg gtggaaacac cgtcatctgt gccacacagg
3541 gaagtgaggg tgaggcaacc cttgagggtg gagatgacaa aggaacatac tgtggggcac
3601 ccattctagg ccccgggggg gcaccaaaat tgagcaccaa aaccaaattt tggaggtcat
3661 cgaacacgcc tcttccacca gggacgtatg agcctgccta cctcggtggc cgtgacccgc
3721 gtgttaaggg tgggccctcc ttgcagcagg taatgagaga ccagttgaag ccattcaccg
3781 agcccagggg taaacctcca agaccaagtg tgttggaagc agccaaacaa accatcatca
3841 acgtcctcga acaaactctg gaccctccac aaaaatggac atacgcacag gcgtgtgctt
3901 cacttgacaa aaccacctcc agcgggcacc cccaccatgt ccgaaagaat gaattctgga
3961 atggtgagac cttcactggt aaattggcag accaagcatc aaaagcaaat ctaatgtttg
4021 aggaagggaa acacatgaca ccagtgtata cagcagccct caaggatgag ctggtcaaga
4081 ctgacaaagt ctatggaaag atcaagaaga gactgctctg gggctctgac ttgtccacca
4141 tgatccggtg cgccaggtcc tttggtgggc tcatggatga gatgaaagca cactgcataa
4201 cactcccagt ccgagttggc atgaacatga atgaagatgg tccaataata tttgagaagc
4261 actccagata caagtatcac tatgatgcag attactcccg ctgggattca acacaacaga
4321 gggcagtgct agcagcagcc ttggagatca tggtcaggtt ctctgcagag ccacaattgg
4381 cacaaatagt cgctgaggat ctgctggccc ccagtgtggt agatgtagga gactttaaaa
4441 tttcaataaa tgaagggctc ccctctggtg taccatgcac ttctcaatgg aattccatcg
4501 cacactggct gctaaccctc tgcgccttgt ctgaagtcac caaactgtcc cctgacatcg
4561 tacaggcaaa ctccatgttc tcattttacg gtgatgacga gattgtcagc accgatataa
4621 aattggaccc tgaaaagtta accaccaaat tgaaggagta cggcctgaaa ccaactcgcc
4681 cagacaaaac cgagggaccc ctgatcatca gtgaggattt gaacggactc actttcctcc
4741 ggagaacggt gactcgtgac ccagctggct ggtttggaaa attggaccaa agctcaatat
4801 tgaggcagat gtactggact agaggaccaa atcatgaaga ccccaacgag acaatgatac
4861 cccactctca aagacccata cagctcatgg cactgcttgg tgaggcctcc cttcacggac
4921 cctctttcta cagcaaaatt agtaagttgg tcataactga actcaaagaa ggtgggatgg
4981 atttttacgt gccaaggcag gaacccatgt tcaggtggat gaggttttct gacttgagca
5041 cgtgggaggg cgatcgcaat ctggctccca attttgtgaa tgaagatggc gtcgaatgac
5101 gccgctccat cgaatgatgg tgcagctagt ctcgtaccag aggccattaa tgagactatg
5161 ccattggaac ccgttgctgg cgcatctatt gctgccccag tggcgggaca aactaacata
5221 attgacccct ggataagaac aaattttgtg caagccccta atggagagtt cacagtatca
5281 ccgagaaatt cccctggaga gattctatta aatttagagt taggaccaga tttgaatcct
5341 tatttggccc atctgtcaag gatgtacaat ggatatgctg gaggtgttga ggtgcaagtg
5401 cttcttgctg ggaacgcgtt cacagcagga aagatattat ttgcagcaat cccacccaac
5461 tttcctgtag atatgattag cccagctcaa attactatgc ttccccattt gattgtagat
5521 gttaggacat tggaacctat tatgataccc ttaccagatg ttaggaatgt gttctatcat
5581 tttaataatc aaccccaacc taggatgaga ttagtggcta tgctctatac cccattgaga
5641 tctaatggtt caggagatga tgtctttact gtgtcttgta gagtgttgac taggccaacc
5701 cctgactttg aattcattta cctagtgcct ccctctgtag agtccaaaac taaaccattc
5761 acacttccaa tattgaccat ttctgaacta accaactccc ggtttcccat cccaattgag
5821 caactgtaca cggccccaaa tgagaataat gttgtacagt gtcaaaatgg aaggtgcacc
5881 ttggatggag agcttcaggg caccacccag ctgctatcaa gtgcagtttg ctcttacagg
5941 ggtaggactg tggctaacag tggggacaat tgggaccaga atttgctcca gctgacctac
6001 ccaagcggtg caagctacga ccccactgat gaagtaccag cacccttggg cacccaggat
6061 ttcagtggga tgttgtatgg ggtgttaacc caagacaatg taagtgaggg tacaggggag
6121 gccaaaaatg ctaagggagt atacatatcc accaccagtg gaagattcac cccaaaaatt
6181 ggaacaattg gattgcattc aataactgaa aatgtgcacc ccaatcagca atcacggttc
6241 acccccgttg gagttgctca gaatgaaaat acccccttcc agcaatgggt tctaccacac
6301 tacgcaggtg ctctcgctct aaacaccaat ttggcacccg ctgttgcccc gactttccct
6361 ggcgagcaat tactgttctt caggtcccgt gttccatgtg ttcaaggtct gcgggggcag
6421 gatgctttca tagattgtct cctacctcaa gagtgggtga accattttta tcaagaggct
6481 gctccctccc aagcagacgt tgccctcatc aggtatgtca accctgatac tggtcgcacg
6541 ctgtttgagg ctaaattgca caggtcaggt ttcattactg tgtcacacac tggtacctac
6601 ccccttgtgg tccccccaaa tggtcatttc aggtttgatt cttgggttaa ccaattctac
6661 tcactcgccc ccatgggaac tggcaatggg cgtagaagag ttcaataatg gcaggagcat
6721 ttatagctgg tctagccggt gacatgctga cttctgctgt tggttcactg acctctgcag
6781 gagccaatgc catcaatcag aaattgaatt ttgattacaa taaacaactc caaaatgcat
6841 cctttcaaca tgataaggaa atgttgcagg cccaaattga tgctacgaag aagctccaat
6901 cagaaatgat tgcaattaag catggggttt tgaccgcggg cggcttttcc ccagctgatg
6961 cagccagagg ggcagtcaac gccccaatga ctcgagtgtt ggattggtca gggacacgct
7021 actacgctcc aaattctgtg caaaccacca gttattccgg gcaattcacc ccctcgccag
7081 tccatcgggc gcaggtgaag tccccttcca attcatctca gcggactgca gctccaagca
7141 gtatccgcag cctgtcaacc caatcaactt ctttaggctc cacctcctca ggggggtcct
7201 ctacaatctc ctctagttcg aggacagcaa actgggtgca acaacaaagg gctcttagcc
7261 cgtacatgca gggagccctg cagacggcat acgtcacacc gccgtctagt agggcttcca
7321 gtatgagctc tgtctcaaca gtgcccaaag gggttttgga ctcctggaca cctgtgttta
7381 acacacgcag gcagccgctg tttgcacacc tcaggaagag gggggagtca caggtttagt
7441 gaaaaggata atcaac
//