Typing tool
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Typing tool
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Complete norovirus genomes
| MK753007 | GII.2 | |
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| GII.P2 |
ORF1: 2..5101
ORF2: 5082..6710
ORF3: 6710..7489
LOCUS MK753007 7533 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P2-GII.2/Washington0526
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK753007
VERSION MK753007.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7533)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7533)
AUTHORS Barclay,L., Cannon,J.L., Tsaknaridis,L.J., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7533
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Washington0526"
/isolate="Hu/US/2016/GII.P2-GII.2/Washington0526"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="08-Jun-2016"
/note="genotype: GII.P2-GII.2"
gene 2..5101
/gene="ORF1"
CDS 2..5101
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS47681.1"
/translation="MKMASNDASAAAAANSNNDNTKSSSDGMLNNMAVTLKRALGARP
KQPAPREKPPRPPRPPTPELIKRIPPPPPNDGDEPTVMFSTVGGVSGLPELTTVDQPP
EANTAFSVPPLSQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
IAKVELTPLSLYWRPVYTPQYLISPDSLRKLHGELFPYTAFENNCYAFCCWVLDLNDS
WLSRRMISRTTGFFRPYQEWNRKPLPTMDDSKLKKVANIVLCALSSLFTRPIKDIIGK
LKPLNILNILASCDWTFAGIVESLILLAELFDVFWTPPDVSAMIAPLLGDYELQGPED
IAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKDEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKNSLAAYMKTLDMEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGKPGIGKTHLAREL
AKKIASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLVNPAPLDYVNFEACSRRIDFLVYADAPEVEK
AKRDFPGQPDMWKDAYRPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTASSLVARA
SGLLHERLDEYELQGPPLSTFNFDRNKIAAFRQLAAENKYGLVDTMRVGNQLRNVTTM
DELKKAIKNIIIRKCQIVYGGNTYTLESDGKGKVVVERVQSTSVQINNEIAGAVHHLR
CARIRYYVRCVQEAIYSLLQIAGTVFVTSRIVSRMNIQNLWSRPLTEEADEATMKEGC
PKPREEEEFIVSSDDIKPEGKKGKNKSGRGKKHTAFSSKGLSDEEYEEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERANLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNERISFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGITEAFGVPIRQVQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEG
TVATILIKRTTGELMPLAARMGTHATMRIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGNAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPQKWTYAQACASLDKTTSSGFPHHVRKNEHW
NGESFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKVYGKIKKRLLWGSDL
ATMVRCARSFGGLMDELKAHCVTLPIRVGMNMNEDGPIVFEKHSRYRYHYDADYSRWD
STQQRAVLAAAMEIMVKFSAEPQLAQIVAEDLLSPSVVDVGDFKISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIVQANSLFSFYGDDEIVSTDIKLDPEKLTGKLR
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTKGP
NHEDPFESMIPHSQRPIQLMSLLGEAALHEPSFYSKISKLVISELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSLVNEDGVE"
mat_peptide 2..991
/gene="ORF1"
/product="p48"
mat_peptide 992..2089
/gene="ORF1"
/product="NTPase"
mat_peptide 2090..2626
/gene="ORF1"
/product="p22"
mat_peptide 2627..3025
/gene="ORF1"
/product="VPg"
mat_peptide 3026..3568
/gene="ORF1"
/product="Pro"
mat_peptide 3569..5098
/gene="ORF1"
/product="RdRp"
gene 5082..6710
/gene="ORF2"
CDS 5082..6710
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47682.1"
/translation="MKMASNDAAPSTDGAAGLVPESNTEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNITITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6710..7489
/gene="ORF3"
CDS 6710..7489
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47683.1"
/translation="MAGAFMAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQVQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPGSMRTTAYSGRFTSTAPVRQADFQHTQSRPTSGSSVSSFATQSSRPTLTTTT
GSSLGTASSNSTRSTNLSQSTVSRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 aatgaagatg gcgtctaacg acgcttctgc tgccgctgct gctaacagca acaacgacaa
61 tacaaaatct tcaagtgacg gaatgcttaa caacatggcc gtcaccctta aacgagccct
121 tggggcccgg cccaaacagc cggccccgag ggagaaaccc ccaagacccc ctagaccacc
181 aacaccagaa ttgatcaaaa gaatcccccc cccaccaccc aatgatgggg acgaaccaac
241 cgtgatgttt agcactgtag gtggcgtgtc tggtctacct gagctcacaa cagttgacca
301 accacctgaa gctaacacgg cctttagtgt gcctcccctc agccaaaggg agaataggga
361 cgctaaggaa ccgttaactg gaaccattct ggaaatgtgg gatggggaga tttatcatta
421 tggactgtat gtggaaagag ggcttgtgtt aggcgtgcac aagccgccgg ctgccatcag
481 catagccaaa gtggagttaa cgcccctctc actgtactgg agacctgttt acacgcctca
541 gtaccttata tctcccgact ccttgaggaa actccatggt gaattgtttc cctacacagc
601 ctttgaaaac aactgttatg ctttctgctg ttgggttttg gatcttaacg attcatggct
661 aagcaggagg atgattagta ggactactgg ctttttcagg ccctaccagg agtggaacag
721 gaagcccctc ccaactatgg atgactcaaa attgaagaag gtcgcgaaca tcgttctgtg
781 tgcattgtca tcactgttca ctagacccat taaggacata attggcaaac tcaaacccct
841 caacatccta aatatcctgg cctcatgcga ctggaccttt gctggcatag tggagtcact
901 aatcctcttg gctgaactct ttgatgtgtt ctggacaccc ccagatgtgt ctgcaatgat
961 cgcacccctc ctcggtgact acgagctgca aggccccgaa gacatcgctg tggagctcgt
1021 gcccgttgtt atgggtggga taggcttggt gttgggattc accaaagaga aaataggtaa
1081 gatgctctcc tctgcagcgt caactctgag ggcatgtaaa gatcttggag cctacgggtt
1141 ggagatccta aaactagtca tgaaatggtt tttcccaaag aaggatgagg ccaacgaact
1201 ggctatggtt agagccattg aagacgctgt actagacctg gaagcaatcg agaacaacca
1261 tatgaccact ctattgaaag acaagaacag ccttgcagcc tacatgaaga ccttggatat
1321 ggaagaggaa aaagctagga aactatccac caaatcagcc tcccctgaca ttgtgggcac
1381 cataaacgcc ctactggcta ggatcgctgc cgcacgttcc ttagttcata gggccaagga
1441 ggagctctcc agtagaccaa gaccagtcgt tctgatgatc tctggcaaac cagggatagg
1501 aaagacccat ctggccagag aattggcaaa gaaaattgca tcaacactca caggagacca
1561 aagggtgggt ctcatcccac ggaatggagt tgaccattgg gacgcctaca aaggtgagag
1621 agtggtgctc tgggatgact acggtatgag caatcccatc cacgatgcac tgaggttgca
1681 ggaattggca gacacatgtc cactaactct gaattgtgac aggattgaaa acaaggggaa
1741 agtcttcgac agcgacgcga tcataatcac caccaatttg gtcaatcccg cgccgctgga
1801 ctatgtcaac tttgaggctt gctccagacg tatagacttc cttgtgtatg ctgatgcccc
1861 agaagtcgag aaagcaaagc gggacttccc cggtcaaccg gacatgtgga aggacgccta
1921 tcgccctgat ttctcacata ttaaattgca acttgcacca caaggtgggt ttgacaaaaa
1981 tggcaacacc ccacatggta aaggagtgat gaagactctc actgccagtt cgctggttgc
2041 gcgtgcctct ggtctcttgc acgagagatt agatgagtac gagttacagg gtccgcccct
2101 ttcaaccttc aactttgacc gcaacaaaat tgcagcgttc agacaactcg ccgctgaaaa
2161 taagtatggt ctggtggaca cgatgagggt gggcaaccag ctcaggaatg ttacgaccat
2221 ggatgaactc aagaaggcta tcaaaaacat tataatcagg aagtgccaga tagtctatgg
2281 cggcaacact tacacgcttg agtctgacgg caagggcaag gttgttgttg agagggtgca
2341 gagcaccagc gtgcaaatta acaatgagat cgctggtgca gtgcatcacc ttaggtgtgc
2401 caggataagg tactatgtca gatgtgtcca agaggccatc tactcactcc tccaaatcgc
2461 cggcacggtg tttgtcactt cacgcatcgt aagccgcatg aatattcaaa atttatggtc
2521 cagaccatta actgaagaag cagatgaggc aaccatgaaa gaggggtgcc ctaaacctag
2581 ggaagaagag gagtttatcg tctcttcgga tgacatcaag ccagagggca agaaaggtaa
2641 gaacaagagt ggccggggca agaaacacac ggcattttca agtaaaggtc tcagtgatga
2701 ggagtatgaa gagtacaaaa ggatcagaga ggagagaaac ggcaaatact ccatagagga
2761 atacctacag gacagagaca aatactacga agaggtggcc attgccaggg caactgaaga
2821 agacttctgt gaagaagaag aggttaagat tcgccagagg atcttcaggc caacaagaaa
2881 gcaacgcaag gaagaaagag ccaaccttgg cctcgtcacc ggatctgaga tcaggaagag
2941 gaatccagat gacttcaaac caaaaggaaa gctgtgggcc gacgatgaca ggagcgtcga
3001 ctacaacgaa agaatcagct ttgaggcccc accgagcatt tggtctagaa ttgttaactt
3061 tggttctgga tgggggtttt gggtgtcacc cagcctcttc ataacatcaa cacatgtcat
3121 acctcaaggc ataactgagg cctttggtgt acccataagg caggttcaaa tacacaaatc
3181 gggcgaattc tgtcgtctga gattcccaaa acccatcagg acggatgtgt caggtatgat
3241 actggaggag ggagcgcctg aaggcactgt tgccaccata ctcatcaaaa gaaccactgg
3301 agagctgatg cctcttgcag caagaatggg cacccacgcg accatgagaa tacaaggacg
3361 cacggtgggc ggccagatgg ggatgctgct tactgggtcc aacgcaaaga gcatggatct
3421 tggcaccacg cccggtgact gtgggtgtcc ctacatttac aaaaggggca acgattacat
3481 agtcattgga gtccacacag cagccgctcg tggcggaaac actgtcatct gcgccacaca
3541 aggtagtgaa ggtgaggcaa cactcgaggg tggtgataat aaaggaacat actgtggggc
3601 accaatccta ggccccggga acgccccaaa actgagcacc aaaactaagt tctggaggtc
3661 ctcaactaca ccactcccac ccggcacgta cgagccggca tatctgggag gaaaagaccc
3721 ccgagtcaaa ggtggaccat ctctgcaaca agttatgcga gaccaactga agccattcac
3781 tgaaccccgt ggtaagccac caaaaccaag tgtccttgaa gctgctaaaa agacaatcat
3841 caatgtgcta gaacaaacaa tagacccccc acaaaagtgg acgtacgcgc aagcgtgcgc
3901 gtcccttgac aaaaccacat ctagtgggtt cccccaccac gtgcgcaaga acgagcactg
3961 gaatggggaa tctttcacag gaaaattggc tgaccaggca tcaaaagcaa acttaatgtt
4021 tgaagagggg aagcacatga ctccagttta cacagctgcc cttaaggatg agctggtcaa
4081 aactgagaaa gtgtatggaa aaataaagaa gaggttgctt tggggctctg acctggccac
4141 catggtgcgg tgcgcgcgct cctttggcgg tctgatggac gaactcaaag cccactgtgt
4201 gacactcccg ataagggttg gcatgaacat gaatgaagat ggaccaatag tctttgaaaa
4261 acattccaga tataggtatc actatgatgc agactattcc aggtgggact caacacagca
4321 aagagccgtt ctggccgcgg ccatggagat catggttaaa ttctcagcag aaccacaact
4381 agcccaaata gttgcagagg acctattgtc gcctagtgta gttgacgtgg gcgacttcaa
4441 aatttccatc aatgaagggt tgccatcggg tgtcccttgc acctctcagt ggaattccat
4501 cgcacattgg ctcctcactt tgtgtgccct ctctgaggtc acagacctct ctcctgacat
4561 tgtacaggcc aactccctct tctccttcta tggagatgat gaaattgtga gcacagatat
4621 taaattggac ccagaaaaac tgacggggaa gttgagagaa tatggtctca aacctactcg
4681 tcctgacaaa actgagggcc ccctgattat cagtgaggat ctgaatggcc tgactttcct
4741 gagaagaacc gtcacccgtg accctgcagg gtggtttggc aaactggacc aaagctccat
4801 acttaggcaa ttgtattgga ccaagggccc caatcatgaa gacccctttg agtcaatgat
4861 tccacactcc cagagaccca tacaactcat gtcactcttg ggtgaggcgg cactgcatga
4921 accatcattt tacagcaaga tcagcaagct tgtgatatct gaattgaaag aaggtggaat
4981 ggatttttac gtgcccaggc aagaacctat gtttaggtgg atgagattct cggatttgag
5041 cacgtgggag ggcgatcgca atcttgctcc cagtcttgtg aatgaagatg gcgtcgaatg
5101 acgccgctcc atctactgat ggtgcagccg gcctcgtgcc agaaagtaat actgaggtca
5161 tggctcttga acccgtggct ggtgccgctt tggcagcccc agtcactggt caaacaaata
5221 ttatagaccc ttggattaga gcaaattttg tccaggcccc caatggtgaa tttacagtct
5281 ccccccgtaa tgcccctggt gaagtgctac taaatctgga gttgggtcca gaattaaatc
5341 cttatctggc acacttagca agaatgtaca acgggtatgc cggtgggatg gaggtgcagg
5401 tcatgttggc tgggaacgcg ttcacagccg gcaagttggt cttcgccgcc gtgccacctc
5461 acttcccggt tgaaaacctt agtccacaac aaattaccat gttccctcat gtgattatag
5521 atgtaaggac tttggaacct gttttattac cactccctga tgttagaaat aatttctttc
5581 attacaatca gaaagatgat cccaagatga gaattgtggc tatgctttat acccccctta
5641 gatcaaatgg ctcaggtgat gatgtgttca cagtctcctg tagggtgtta actaggccct
5701 cccctgactt tgacttcaca tatctggtgc caccaacagt ggagtctaaa acaaaaccat
5761 tcaccctccc aatcctcaca cttggggaac tttccaattc cagattccca gtgtctatag
5821 accagatgta caccagccct aatgaagtta tatcagtgca gtgtcaaaat ggtaggtgca
5881 cattggacgg ggagctccaa gggacaacac aactccaggt cagtggcatt tgtgctttca
5941 agggagaggt gaccgcccat ttgcatgata atgatcacct atacaatatc accatcacaa
6001 acttgaatgg atcccctttt gacccctctg aggacatccc tgcccctctg ggcgtacctg
6061 actttcaggg aagggtcttt ggtattatct cccaaaggga caaacacaat agccctggac
6121 ataatgaacc agcaaacagg gggcacgacg ctgtggtccc tacttacaca gcacagtata
6181 ctccaaaatt gggtcagatt caaattggca catggcagac tgacgatctc actgtcaacc
6241 aaccagtaaa attcacccca gttggactca atgacactga acattttaac caatgggtgg
6301 tccccagata tgctggtgcc ctaaacctca acacaaacct tgccccttct gttgccccag
6361 tatttccagg ggagcgcctg ctctttttca gatcatacat ccccctcaag ggtggctatg
6421 gaaatccagc cattgattgc ctactaccac aagagtgggt gcaacacttc taccaggaag
6481 cagccccttc aatgagtgag gtggcccttg tcaggtacat caacccggac actggtcggg
6541 cactgtttga ggccaagctc cacagagctg gtttcatgac ggtctcaagt aacaccagtg
6601 ccccggtggt tgtacctgcc aatggatact tcaggtttga ctcttgggtg aaccaatttt
6661 attctctcgc ccccatggga actggaaatg ggcgtagaag ggttcaataa tggctggagc
6721 ttttatggct ggtcttgcag gggacgtgct cagtaatggg ctcagttcac taattaatgc
6781 aggtgctaat gcaataaatc agagggcaga atttgatttt aatcagaaat tacagcaaaa
6841 ttcttttaat catgacaagg aaatgttgca ggctcaggtt caagcaacta agcagctgca
6901 agcagacatg atggctataa agcagggggt cctgaccgct ggcggctttt cccccgctga
6961 tgcagccaga ggtgctgtga atgcgcccat gacacaagcg ctggattgga acggcacaag
7021 gtattgggca ccaggctcca tgaggaccac agcttactct gggagattca catcaaccgc
7081 cccagtgagg caggccgact ttcagcacac ccaaagccgg cccacgagtg gctcttctgt
7141 gtcctccttt gccactcagt cttcaagacc aactttgacc acaaccactg ggtcctcact
7201 tggtacagct tcatcaaatt cgactcgcag taccaacctc tcccaatcaa cagtttccag
7261 agctacatct aggactggtg agtgggttag agaccaaaat agaaatttgg aaccctatat
7321 gcatggtgcc ttacagacag cctttgtcac cccaccttcc agcagggcgt ctgacgggac
7381 agtctcaacc gtcccaaaag gtgttttgga ctcctggaca cctgcgttca acacccgcag
7441 gcagccgctt tttgcacacc tccgtaagag gggggagtca caagcttagt gaaaaggtga
7501 aaatctattt agaattaatt gatcttacct ttt
//