Typing tool
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Typing tool
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Complete norovirus genomes
| MK752947 | GII.13 | |
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| GII.P16 |
ORF1: 4..5100
ORF2: 5081..6709
ORF3: 6709..7440
LOCUS MK752947 7448 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2014/GII.P16-GII.13/Winnebago0598
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK752947
VERSION MK752947.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7448)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7448)
AUTHORS Barclay,L., Cannon,J.L., Davis,T., Montmayeur,A.M., Tatusov,R.L.
and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7448
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Winnebago0598"
/isolate="Hu/US/2014/GII.P16-GII.13/Winnebago0598"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="17-Feb-2014"
/note="genotype: GII.P16-GII.13"
gene 4..5100
/gene="ORF1"
CDS 4..5100
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS47672.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDNSQKPPRPPTPELVKRIPPPPPNGEEEEPVIRYEVKSGISGLPELTTVPQP
DVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAI
SMAKVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLND
SWLNRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIG
KIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPE
DLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFF
PKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLS
TKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLARE
VARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADT
CPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVE
KAKRDFPGQPDMWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIAR
ASGLLHERMDEFELQGPTVTTFNFDRNRIAAFRQLAAENKYGLVDTMRIGNQLKGVKT
MEELKQAIKNVIIKRCRIIYGGSTYDLESDGKGRVLVEKVKNTSVQTNNELAGALHHL
KHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIVRRMNIQELWSKPPLGQNESEAKEEA
PKSEDDEFIISSKDIREEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGK
YSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERVTLGLVT
GSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPS
LFITSTHVIPAGITEAFGVPIKQIQVHKSGEFCRFRFPKPIRSDVTGMILEEGAPEGT
VATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDC
GCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGP
GGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPR
GKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFWN
GETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTDKVYGKIKKRLLWGSDLS
TMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDS
TQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKISINEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTKLSPDIVQANSMFSFYGDDEIVSTDIKLDPEKLTTKLKE
YGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPN
HEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 4..996
/gene="ORF1"
/product="p48"
mat_peptide 997..2094
/gene="ORF1"
/product="NTPase"
mat_peptide 2095..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3024
/gene="ORF1"
/product="VPg"
mat_peptide 3025..3567
/gene="ORF1"
/product="Pro"
mat_peptide 3568..5097
/gene="ORF1"
/product="RdRp"
gene 5081..6709
/gene="ORF2"
CDS 5081..6709
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47673.1"
/translation="MKMASNDAAPSNDGAASLVPEAINETMPLEPVAGASIAAPVAGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAIPPNFPVDMISPAQITMLPHLIVDVRTLEPIMIPLPD
VRNVFYHFNNQPQPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFIYLVPP
SVESKTKPFTLPILTISELTNSRFPIPIEQLYTAPNENNVVQCQNGRCTLDGELQGTT
QLLSSAVCSYRGRTVANSGDNWDQNLLQLTYPSGASYDPTDEVPAPLGTQDFSGILYG
VLTQDNVSEGTGEAKNAKGVYISTTSGRFTPKIGTIGLHSITENVHPNQQSRFTPVGV
AQNENTPFQQWVLPHYAGALALNTNLAPAVAPTFPGEQLLFFRSRVPCVQGLRGQDAF
IDCLLPQEWVNHFYQEAAPSQADVALIRYVNPDTGRTLFEAKLHRSGFITVSHTGTYP
LVVPPNGHFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6709..7440
/gene="ORF3"
CDS 6709..7440
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47674.1"
/translation="MAGAFIAGLAGDMLTSAVGSLTSAGANAINQKLNFDYNKQLQNA
SFQHDKEMLQAQIEATKKLQSEMIAIKHGVLTAGGFSPADAARGAVNAPMTRVLDWSG
TRYYAPNSVQTTSYSGQFTPSPVHRAQVKSLSNSSQRTAAPSSIRSLSTQSTSLGSTS
SGGSSTTSSRSRTADWVQQQRALSPYMQGALQTAYVTPPSSRASSVSSVSTVPKGVLD
SWTPVFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 tgaatgaaga tggcgtctaa cgacgctacc gttgccgttg cttgcaacaa caacaacgac
61 aaggaaaaat cttcaggtga aggcttattc acaaatatgt cttccacctt aaagaaggcc
121 ctcggggccc ggcccaaaca gcctgccccg agggacaact cacaaaagcc cccaagacca
181 ccaactcccg agttggttaa gaggataccc cctcccccac ctaatggaga agaagaagaa
241 ccagtcatta ggtatgaggt taagagtgga atctctggcc tgcccgagct cacaacagtc
301 cctcaaccgg atgtggccaa cacggcattc agtgtcccac cgctgagctt gagagaaaac
361 agggaggcca aggaaccgct gacaggggca atattagaga tgtgggatgg agagatatac
421 cactatggcc tgtatgtgga gaaaggctta gtgttgggag tgcacaaacc acctgcagct
481 ataagcatgg caaaagtgga gctgacgccg ttgtcattgt actggcgtgt agtctacacc
541 ccccaatacc tcatctcccc tgaaactctc agaaggctca acggagaggc attcccttac
601 actgcctttg acaacaactg ctatgccttt tgctgctggg tgttagacct caatgactca
661 tggcttaaca ggaggatggt gcaaagaaca acaggcttct tcagacctta ccaagagtgg
721 aacagaaaac ccctgcccac tatggatgac tccaaaatca agaaagtggc aaacatattc
781 ctgtgttcat tgtccacgtt gttcaccaga cctataaaag acctcatagg aaaaattaag
841 ccattaaaca tcttgaacat cctggcaacg tgtgactgga cattcgccgg aatagtggag
901 tctctgatat tacttgctga actctttgga gttttctgga cacccccaga tgtgtctgct
961 atgatcgctc ctttacttgg agactacgag ttgcaagggc cagaagacct tgccgttgag
1021 ctcgtacctg tagtaatggg agggatcggt ttggtgttgg gattcaccaa agagaaaatt
1081 ggaaaaatgt tgtcctcagc agcatcaacg ctcagggctt gtaaagatct tggcgcctat
1141 ggcttagaga tactcaaatt ggtcatgaag tggttcttcc caaagaaaga agaggccaat
1201 gagctagcca tggtgagagc tatagaggat gctgtactgg atcttgaggc aatagaaaat
1261 aatcacatga caactctgtt gaaagacaaa gacagcctag caacctacat gaaaacacta
1321 gacatggagg aggaaaaagc cagaagattg tccacaaaat ctgcatcccc tgacatagtt
1381 gggacgatca acgccctgct ggctcgtata gcagcggcta ggtcactagt ccacagggcc
1441 aaggaggagt tatctagcag gataagacca gtggtcgtta tgatatccgg caaaccaggg
1501 ataggcaaaa ctcatttggc cagggaggtg gcaagaaagg tggcatccac tctcacaggg
1561 gatcaaagag tcgggctcat accgagaaac ggtgtggacc attgggatgc atacaaaggt
1621 gagagagtcg tgctgtggga cgactatggc atgagcaacc ccattcatga tgctctgcgc
1681 atacaagaat tggctgatac gtgtcccctc accttaaatt gtgacagaat tgaaaataag
1741 ggaaaagtct ttgacagtga agtcataata atcacaacaa accttgccaa tccagctcca
1801 cttgattatg tcaactttga ggcctgttcc aggagaattg acttcctggt gtacgccgag
1861 gcaccagaag tggaaaaggc aaaacgagac tttcctggtc aaccagatat gtggaaggac
1921 gccttcaagt cggacttttc acacatcaag ttgcaacttg cacctcaggg cggctttgac
1981 aagaatggca acaccccaca tgggaaagga gtgatgaaaa ccctcaccac cggttccctg
2041 atcgcccgtg catcaggttt actgcatgag aggatggatg aatttgaact ccaaggcccc
2101 acagtcacca ccttcaattt tgaccggaac agaatcgctg ctttcagaca attggctgca
2161 gaaaacaagt atggattggt ggacaccatg agaattggca atcaattaaa aggggtgaaa
2221 accatggaag aactcaaaca agcaatcaag aatgtgatca tcaagaggtg ccggatcatc
2281 tacggcggct ccacgtatga ccttgaatct gatggcaagg gtagagttct ggtggaaaag
2341 gtcaagaaca cctctgtaca gaccaacaac gagttggccg gagccctgca tcacctcaaa
2401 catgcccgaa tcaggtacta cgtcaaatgt gtgcaagaag cagtctactc tattatacaa
2461 atcgccggtg ctgcgtttgt caccacacgc atagtacgcc gcatgaacat acaagagctt
2521 tggtcgaagc caccattagg ccaaaatgaa tcagaggcta aggaagaggc ccccaagtca
2581 gaagatgacg agttcatcat atcttctaag gacatcaggg aggaaggaaa gaagggcaaa
2641 aacaaaactg gccgtggcaa gaaacatact gcattctcta gcaagggctt gagcgatgag
2701 gagtatgacg agtacaagag gataagagaa gagagaaatg ggaagtactc tatagaggag
2761 tatcttcaag acagagacag gtactatgag gaactcgcca tcgccaaggc cacggaagaa
2821 gacttctgtg aggaggagga gatcaaaatc cgtcagagga tcttccgtcc caccaggaag
2881 caaaggaagg aagagagggt cacactaggg ctggtaactg gttcagaaat cagaaaaaga
2941 aaccctgatg acttcaaacc taaagggaaa ctgtgggctg atgacaacag aagtgttgac
3001 tacaatgaga aactggactt tgaggccccc ccaagcatat ggtctaggat tgtgagtttt
3061 ggttctggtt ggggcttctg ggtgtcacca agcctgttca taacatcaac tcatgtaatc
3121 cctgcaggca taacagaggc atttggagtc cccatcaaac aaatccaggt ccacaaatca
3181 ggtgaatttt gccggttcag attcccaaaa ccaattagat cagatgtgac agggatgatc
3241 ctggaagaag gtgcgcctga gggcaccgtg gcaaccgtgc tcatcaaacg ccctaccgga
3301 gagctcatgc cccttgcagc cagaatggga acacacgcaa ccatgaaaat tcagggccgc
3361 atggttggcg gacagatggg tatgttgctc actggttcaa atgctaaagg aatggatttg
3421 ggaacaactc ctggtgattg tggctgtccc tacatctaca aaaggggcaa tgactacata
3481 gtcattgggg tgcatacagc agcagcccgt ggtggaaaca ccgtcatctg tgccacacag
3541 ggaagtgagg gtgaggcaac tcttgagggt ggagatgaca aagggacata ctgtggggca
3601 cccattctag gccctggggg ggcaccaaaa ttgagcacca aaaccaaatt ttggaggtca
3661 tcgaacacgc ctcttccacc agggacgtat gagcctgcct acctcggtgg ccgtgacccg
3721 cgtgttaagg gtgggccctc cttgcagcag gtaatgagag accagttgaa gccattcacc
3781 gagcccaggg gtaaacctcc aagaccaagt gtgttggaag cagccaaaca aaccatcatc
3841 aatgtcctcg aacaaaccct ggaccctcca caaaaatgga catacgcaca ggcgtgtgct
3901 tcacttgaca aaaccacctc cagcgggcat ccccaccacg tccgaaagaa tgaattctgg
3961 aatggtgaga ccttcactgg taaattggca gaccaagcat caaaagcaaa tctaatgttt
4021 gaggaaggga aacacatgac accagtgtat acagctgccc tcaaggatga gctagtcaag
4081 actgacaaag tctatggaaa gatcaagaag agactgctct ggggctctga cttgtccacc
4141 atgatccggt gcgccaggtc ctttggtggg ctcatggatg aaatgaaagc acactgcata
4201 tcactcccag tccgagttgg catgaacatg aatgaagatg gtccaataat ttttgagaag
4261 cactccagat acaagtatca ctatgatgca gattactccc gctgggattc aacacaacag
4321 agggcagtac tagcagcagc cttggagatc atggtcaggt tctctgcaga gccacaattg
4381 gcacaaatag tcgctgagga tctgctggcc cccagtgtgg tagatgtagg agactttaaa
4441 atttcaataa atgaagggct cccctctggt gtaccatgca cttctcaatg gaattccatc
4501 gcacactggc tgctaaccct ctgcgccttg tctgaagtca ccaaactgtc ccctgacatt
4561 gtacaggcaa attccatgtt ctcattttac ggtgatgacg agattgtcag caccgatata
4621 aaattggacc ctgaaaagtt aaccaccaaa ttgaaggagt acggcctgaa accaacccgc
4681 ccagacaaaa ccgagggacc cctgatcatc agtgaggatc tgaacggact cactttcctc
4741 cggaggacgg tgactcgtga cccagctggc tggtttggaa aattggacca aagttcaata
4801 ttgaggcaga tgtactggac tagagggcca aatcatgaag accccaatga gacaatgata
4861 ccccactctc agagacccat acagctcatg gcactgcttg gtgaggcctc ccttcacgga
4921 ccctcttttt acagcaaaat tagcaagttg gtcataactg aactcaaaga aggtgggatg
4981 gacttttacg tgccaaggca ggaacccatg ttcaggtgga tgaggttttc tgacttgagc
5041 acgtgggagg gcgatcgcaa tctggctccc aattttgtga atgaagatgg cgtcgaatga
5101 cgccgctcca tcgaatgatg gtgcagctag tctcgtacca gaggccatta atgagactat
5161 gccattggaa cccgttgctg gcgcatctat tgctgcccca gtggcgggac aaactaacat
5221 aattgacccc tggataagaa caaattttgt gcaagcccct aatggagagt ttacagtatc
5281 acccagaaat tcccctggag agatcctatt gaatttagag ttaggaccag atttgaatcc
5341 ttacttggcc catctatcaa ggatgtacaa tggatatgct ggaggtgttg aggtgcaagt
5401 gcttcttgct gggaacgcgt tcacagcagg aaagatatta tttgcagcaa tcccacccaa
5461 ctttcctgta gatatgatta gcccagctca aattactatg cttccccatt tgattgtaga
5521 tgttaggaca ttggaaccta ttatgatacc cttacctgat gttaggaatg tgttttatca
5581 ttttaataat caaccccaac ctaggatgag attagtggct atgctctata ccccattgag
5641 atctaatggt tcaggagatg atgtctttac tgtgtcttgt agagtgttga ctaggccaac
5701 tcctgacttt gaattcattt acctagtgcc tccctctgta gagtccaaaa ctaaaccatt
5761 cacacttcca atattgacca tttctgaact aaccaactcc cggtttccca tcccaattga
5821 gcaactgtac acggccccaa atgagaataa tgttgtacag tgtcaaaatg gaaggtgcac
5881 cttggatgga gagcttcagg gcaccaccca gctgctatca agtgcagttt gctcttacag
5941 gggcaggact gtggctaaca gtggggacaa ttgggaccag aatttgctcc agctgaccta
6001 cccaagcggt gcaagctatg accccactga tgaagtacca gcacccttgg gcacccaaga
6061 tttcagtggg atattgtatg gggtgttaac ccaagacaat gtaagtgagg gtacagggga
6121 ggctaaaaat gctaagggag tatacatatc caccaccagt ggaagattca ccccaaaaat
6181 tgggacaatt ggattgcatt caataactga aaatgtgcac cccaatcagc aatcacggtt
6241 cacccccgtt ggggtcgctc agaatgaaaa cacccccttc cagcaatggg ttctaccaca
6301 ctacgcaggt gctcttgctc taaacaccaa tttggcaccc gctgttgccc cgactttccc
6361 tggcgaacaa ttactgttct tcaggtcccg tgttccatgt gttcaaggtc tgcgggggca
6421 ggatgctttc atagattgtc tcctacctca agagtgggtg aaccattttt atcaagaggc
6481 tgctccctcc caagcagacg ttgccctcat caggtatgtc aaccctgata ctggtcgcac
6541 gctgtttgag gccaaattgc acaggtcagg tttcattact gtatcacaca ctggtaccta
6601 ccctcttgtg gtccccccga atggtcattt caggtttgat tcttgggtta accaattcta
6661 ctcactcgcc cccatgggaa ctggcaatgg gcgtagaaga gttcaataat ggcaggagca
6721 tttatagctg gtctagccgg tgacatgctg acttctgctg ttggttcact gacctctgca
6781 ggagccaatg ccatcaatca gaaattgaat tttgactaca ataaacaact ccaaaatgca
6841 tcctttcaac atgataagga aatgttgcag gcccaaattg aagctacaaa gaagctccaa
6901 tcagaaatga ttgcaattaa gcatggggtt ttgaccgcgg gcggcttttc cccagctgat
6961 gctgccagag gggcagtcaa cgccccaatg actcgagtgt tggattggtc agggacacgc
7021 tactacgctc caaattctgt gcaaaccacc agttactctg ggcaattcac cccctcgcca
7081 gtccatcggg cgcaggtgaa gtccctttcc aattcatctc agcggactgc agctccaagc
7141 agtatccgca gcctgtcaac ccaatcaact tctttgggct ccacctcctc aggggggtcc
7201 tctacaacct cctctagatc gaggacagca gactgggtgc aacaacaaag ggctcttagc
7261 ccgtacatgc agggagccct gcagacggca tacgttacac cgccgtctag tagggcttcc
7321 agtgtgagct ctgtctcaac agtgcccaaa ggggttttgg actcctggac acctgtgttt
7381 aacacacgca ggcagccgct gtttgcacac ctcaggaaga ggggggagtc acaggcttag
7441 tgaaaagg
//