Typing tool
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Typing tool
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Complete norovirus genomes
| MK752945 | GII.2 | |
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| GII.P2 |
ORF1: 1..5094
ORF2: 5075..6703
ORF3: 6703..7482
LOCUS MK752945 7487 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2015/GII.P2-GII.2/Dane0589
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK752945
VERSION MK752945.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7487)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7487)
AUTHORS Barclay,L., Cannon,J.L., Davis,T., Montmayeur,A.M., Tatusov,R.L.
and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7487
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Dane0589"
/isolate="Hu/US/2015/GII.P2-GII.2/Dane0589"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="29-Apr-2015"
/note="genotype: GII.P2-GII.2"
gene <1..5094
/gene="ORF1"
CDS <1..5094
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS47666.1"
/translation="MASNDASAAAAVNSNNDNTKSSSDGMLNNMAVTLKRALGARPKQ
PAPREKPPRPPRPPTPELTKRIPPPPPNDGDEPTVMFSTAGGVSGLPELTTVGQPPEA
NTAFSVPPLSQRENRDAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISIA
KVELTPLSLYWRPVYTPQYLISPDTLRKLHGELFPYTAFENNCYAFCCWVLDLNDSWL
SRRMISRTTGFFRPYQEWNRKPLPTMDDSKLKKVANIVLCALSSLFTRPIKDIIGKLK
PLNILNILASCDWTFAGIVESLILLAELFDVFWTPPDVSAMIAPLLGDYELQGPEDIA
VELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKK
DEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKNSLAAYMKTLDMEEEKARKLSTKS
ASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGKPGIGKTHLARELAK
KIASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPL
TLNCDRIENKGKVFDSDAIIITTNLVNPAPLDYVNFEACSRRIDFLVYADAPEVEKAK
RDFPGQPDMWKDAYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTASSLIARASG
LLHERLDEYELQGPPLSTFNFDRNKIAAFRQLAAENKYGLVDTMRVGNQLRNVTTMDE
LKKAIKNIIIRKCQIVYGGNTYTLESDGKGKVVVEKVQSASVQINNEIAGAVHHLRCA
RIRYYVKCVQEAIYSLLQIAGTVFVTSRIVSRMNIQNLWSRPLTEDADEATIKEGCPK
PRDEEEFIVSSDDIKPEGKKGKNKSGRGKKHTAFSSKGLSDEEYEEYKRIREERNGKY
SIEEYLQDRDKYYEEVAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERANLGLVTG
SEIRKRNPDDFKPKGKLWADDDRSVDYNERISFEAPPSIWSRIVNFGSGWGFWVSPSL
FITSTHVIPQGITEAFGVPIRQVQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEGTV
ATILIKRTTGELMPLAARMGTHATMRIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCG
CPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPG
NAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRG
KPPKPSVLEAAKKTIINVLEQTIDPPQKWTYAQACASLDKTTSSGYPHHVRKNEHWNG
ESFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKVYGRIKKRLLWGSDLAT
MVRCARSFGGLMDELKAHCVTLPIRVGMNMNEDGPIVFEKHSRYRYHYDADYSRWDST
QQRAVLAAAMEIMVKFSAEPQLAQIVAEDLLSPSVVDVGDFKVSINEGLPSGVPCTSQ
WNSIAHWLLTLCALSEVTDLSPDIVQANSLFSFYGDDEIVSTDIKLDPEKLTGKLREY
GLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTKGPNH
EDPFESMIPHSQRPIQLMSLLGEAALHEPSFYSKISKLVIAELKEGGMDFYVPRQEPM
FRWMRFSDLSTWEGDRNLAPSLVNEDGVE"
mat_peptide <1..984
/gene="ORF1"
/product="p48"
mat_peptide 985..2082
/gene="ORF1"
/product="NTPase"
mat_peptide 2083..2619
/gene="ORF1"
/product="p22"
mat_peptide 2620..3018
/gene="ORF1"
/product="VPg"
mat_peptide 3019..3561
/gene="ORF1"
/product="Pro"
mat_peptide 3562..5091
/gene="ORF1"
/product="RdRp"
gene 5075..6703
/gene="ORF2"
CDS 5075..6703
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47667.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6703..7482
/gene="ORF3"
CDS 6703..7482
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47668.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPSSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTASSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 atggcgtcta acgacgcttc tgctgccgct gctgtcaaca gcaacaacga caacacaaaa
61 tcttcaagtg acggaatgct taataacatg gccgtcaccc ttaaacgagc ccttggggcc
121 cggcccaaac agccagcccc gagggaaaaa cccccaagac cccctagacc accgacacca
181 gaactaacca agagaatccc ccccccacca cctaatgatg gggacgaacc aaccgtgatg
241 tttagcactg caggtggtgt gtctggccta cctgagctca caacagtcgg tcaaccacct
301 gaagctaaca ctgcctttag tgtgcccccc cttagccaaa gggaaaacag ggacgctaag
361 gaaccgctaa ctggggctat tctggaaatg tgggacgggg agatttatca ttatggactg
421 tatgtggaaa aagggcttgt gctaggcgtg cacaagccgc cggctgccat cagcatagcc
481 aaagtggaat tgacacccct ctcactgtat tggaggcctg tgtacacgcc tcagtacctc
541 atatctcctg acaccttgag gaaactccac ggtgagttat ttccctatac agcctttgaa
601 aacaactgtt atgccttctg ctgttgggtt ttggacctca acgattcatg gttaagcaga
661 aggatgatta gtaggactac tggcttcttc aggccctacc aagagtggaa caggaagcct
721 ctcccaacta tggatgactc aaaattgaag aaggtcgcaa acatcgttct gtgtgcattg
781 tcatcattgt tcactagacc cattaaggat ataattggca aacttaaacc ccttaacatc
841 ctaaatattc tggcctcatg cgattggacc ttcgctggca tagtagaatc actaatcctc
901 ttggctgaac tctttgatgt gttctggaca cccccagatg tgtctgcaat gatcgcaccc
961 ctcctcggcg actatgagct acaaggtccc gaagacatcg ctgtggagct cgtgcccgtt
1021 gtgatgggtg ggataggtct ggtgttggga ttcaccaaag agaaaatagg taagatgctc
1081 tcctctgcag cgtcaactct gagggcgtgc aaagatcttg gagcctatgg attggagata
1141 ctgaaactag tcatgaaatg gtttttccca aagaaggatg aggccaacga actggctatg
1201 gttagagcca ttgaagacgc tgtattagac ctggaggcta ttgagaacaa ccatatgacc
1261 actctattga aagacaagaa cagccttgca gcatacatga agaccctgga catggaagag
1321 gaaaaagcta ggaagctatc caccaaatca gcttcccctg acattgtggg cactataaac
1381 gccctgctgg ctaggatcgc tgccgcgcgt tccttagttc atagggccaa ggaggagctc
1441 tccagcaggc caagaccggt cgttttgatg atctctggca agccagggat aggaaagacc
1501 cacttggcca gagaactggc aaagaaaatt gcctcgacac tcacaggaga ccaaagggtt
1561 ggtcttatcc cacggaatgg agttgaccat tgggacgcct acaaaggtga gagagtggtg
1621 ctctgggatg actacgggat gagcaacccc atccacgatg cgctgaggct gcaggaattg
1681 gcagacacat gtccattaac tctgaattgt gacaggattg aaaacaaggg gaaagtcttc
1741 gacagcgacg cgatcataat caccaccaat ttggtcaacc ccgcgccgct ggattatgtc
1801 aactttgagg cctgctccag gcgtatagac ttccttgtgt atgctgatgc cccagaagtc
1861 gagaaagcaa agcgggactt tcccggtcaa ccggacatgt ggaaggacgc ctatcgctct
1921 gacttctcac acattaaact acaacttgca ccacaaggtg ggtttgacaa aaatggcaac
1981 accccacatg gtaaaggagt gatgaagaca ctcaccgcca gctcactgat cgcacgtgcc
2041 tctggtctct tgcacgagag attagatgag tacgagttac aaggtccacc cctctcaacc
2101 ttcaactttg accgtaacaa aattgcagcg tttagacaac tcgccgctga aaacaagtac
2161 ggtctggtag acacgatgag ggtgggcaac cagctcagaa atgtcacgac catggatgaa
2221 ctcaagaagg ctatcaagaa catcataatt agaaagtgcc agatagtcta tggtggcaac
2281 acttacacgc ttgagtctga cggcaagggc aaggttgtag ttgagaaagt gcagagcgcc
2341 agcgtgcaaa tcaacaatga gatcgctggt gcagtacacc atcttagatg tgccagaata
2401 aggtattatg tcaagtgtgt ccaagaggcc atatactcac tcctccagat tgccggcacg
2461 gtgtttgtca cttcacgcat cgtaagccgc atgaacatcc aaaatctgtg gtctaggcca
2521 ctaactgaag atgcggatga ggccaccata aaagaggggt gccctaaacc tagggatgaa
2581 gaagaattta tcgtctcctc agatgatatc aagccagagg gtaagaaagg taaaaacaag
2641 agtggccggg gcaagaaaca cacggcattc tcaagtaaag ggctcagtga tgaggagtac
2701 gaagagtaca aaagaatcag agaggagaga aatggcaagt actccataga ggaataccta
2761 caggacagag acaagtacta tgaagaggtg gccattgcca gggcaactga agaagacttc
2821 tgcgaagaag aagaggttaa gattcgtcag aggatcttca ggccaacaag aaagcaacgc
2881 aaggaagaga gagccaacct tggcctcgtt accgggtctg agatcaggaa gaggaaccca
2941 gatgacttta aaccaaaagg aaagctgtgg gccgacgatg acaggagcgt cgactacaat
3001 gaaagaatca gctttgaggc cccaccaagc atttggtcta gaattgtcaa ctttggttct
3061 ggatgggggt tctgggtgtc acctagcctc ttcataacat caacacacgt tatacctcaa
3121 ggcataactg aggcctttgg tgtgcccata aggcaggtgc aaatacacaa atcgggcgag
3181 ttctgtcgcc tgagattccc aaaacccatc agaacagatg tgtcaggcat gatactggag
3241 gagggagcgc ccgaaggtac tgttgccacc atactcatca aaagaaccac tggagagctg
3301 atgcctctag cagcaagaat gggcacccac gcgaccatga ggatacaagg gcgcacagtg
3361 ggcggccaga tgggaatgct gctcactggg tccaatgcaa agagcatgga tcttggcacc
3421 acgcccggtg actgtgggtg tccctacatt tacaaaaggg gtaatgatta catagtcatt
3481 ggggttcaca cagcagccgc tcgtggcgga aacactgtca tctgcgccac acaaggtagt
3541 gagggtgagg ctactctcga gggtggtgac aataaaggaa catactgtgg ggcaccaatc
3601 ttaggccccg ggaatgcccc aaaactgagc actaaaacca agttctggag gtcctccaca
3661 acaccactcc cacccggcac gtacgagccg gcatatctgg gaggaaaaga cccccgagtc
3721 aaaggtggac catctctgca acaagtcatg cgagaccaac tgaagccatt caccgaaccc
3781 cgtggcaagc caccaaaacc aagtgtcctt gaagctgcta aaaagacaat tatcaatgta
3841 ttagagcaaa caatagaccc cccacagaag tggacgtacg cgcaagcgtg cgcgtctctt
3901 gacaaaacca catctagtgg gtacccccac cacgtgcgca aaaacgagca ctggaatggg
3961 gaatctttca caggaaaact ggctgatcag gcatcgaagg caaacctaat gtttgaagag
4021 gggaaacaca tgaccccagt ttatacagct gcccttaagg atgagttggt caaaactgag
4081 aaagtgtatg ggaggataaa gaagaggttg ctttggggct ctgacttggc caccatggtg
4141 aggtgtgcgc gctcctttgg cggtttgatg gacgaactca aggcccactg tgtgacactc
4201 ccgataaggg ttggcatgaa tatgaatgaa gatggaccaa tagtctttga gaaacattcc
4261 agatacaggt atcactatga tgcagactac tccaggtggg actcaacaca gcagagagcc
4321 gttctggccg cggccatgga gattatggtt aaattctcag cagaaccaca attagcccaa
4381 atagttgcag aggatctgtt gtcgcccagt gttgttgacg tgggcgactt caaagtttcc
4441 atcaacgaag gattaccatc gggcgtccct tgcacctctc aatggaactc cattgcacac
4501 tggctcctca ccttgtgtgc cctttctgaa gtcacagatc tctctcctga cattgtgcaa
4561 gccaactctc tcttctcctt ctatggtgat gatgaaattg tgagtacaga tatcaaatta
4621 gacccagaaa agttgacggg gaagttgaga gaatatggtc tcaaacccac tcgtcctgac
4681 aaaactgagg gccccttgat tattagcgag gatctgaatg gcctgacctt cctgaggaga
4741 accgtcaccc gcgaccctgc aggatggttt ggcaaactgg accaaagctc tatacttagg
4801 caattgtatt ggaccaaagg ccctaatcat gaagacccct ttgagtcaat gattccacat
4861 tcccagagac ccatacaact catgtcactc ttgggtgaag cagcactgca tgaaccatca
4921 ttttacagca agatcagcaa gcttgtgata gctgagttga aagaaggtgg aatggatttt
4981 tacgtgccca ggcaagaacc tatgtttagg tggatgagat tctcggattt gagcacgtgg
5041 gagggcgatc gcaatcttgc tcccagtctt gtgaatgaag atggcgtcga atgacgccgc
5101 tccatctact gatggtgcag ccggcctcgt gccagaaagt aacaatgagg tcatggctct
5161 tgaacccgtg gctggtgccg ccttggcagc cccggtcacc ggtcaaacaa atattataga
5221 cccttggatt agagcaaatt ttgtccaggc ccccaatggt gaatttacag tctctccccg
5281 aaacgcccct ggtgaagtgc tactgaatct agagttgggt ccagaattaa atccttatct
5341 ggcacattta gcaagaatgt acaatgggta tgccggtgga atggaggtgc aggtcatgtt
5401 ggctgggaac gcgttcacag ccggcaagtt ggtcttcgcc gccgtgccac ctcacttccc
5461 ggttgaaaac cttagcccac agcaaatcac catgttccct catgtgatca tagatgtgag
5521 aaccttggaa cctgttttat taccactccc tgatgttagg aataatttct tccattataa
5581 tcagaaagat gatcccaaga tgagaattgt ggctatgctt tatacccccc tcaggtctaa
5641 tggttcaggt gatgacgtgt ttacagtctc ctgcagagtg ttgactagac cttcccctga
5701 ttttgacttt acatacctgg tgccaccaac agtggagtct aaaacaaaac cattcaccct
5761 cccaatcctc acacttgggg aactttccaa ttctaggttc ccagtgtcca tagaccagat
5821 gtacaccagc cctaatgaag ttatatcagt gcagtgtcaa aatggtaggt gcacattgga
5881 cggggagctc caagggacaa cacaactcca agtcagtggc atttgtgctt tcaaaggtga
5941 agtgaccgcc cacttgcatg acaatgatca cctatataat gttaccatca caaacttgaa
6001 tgggtcccct tttgatccct ccgaggatat ccctgcccct ctgggtgtgc ctgacttcca
6061 gggaagagtc tttggtatca tctcccaaag agacaaacac aatagtcctg ggcacaacga
6121 accagcaaac aggggacacg acgctgtggt ccctacttac acagcacagt acactccaaa
6181 actgggacaa attcaaattg gcacatggca aactgacgac cttacagtca accaaccagt
6241 caaattcacc ccagttggac tcaatgacac tgaacacttt aaccaatggg tggtccctag
6301 gtatgctggt gccctaaatc tcaatacaaa ccttgctcct tctgtcgctc cagtattccc
6361 aggagagcgc ctactcttct tcagatcata cattcccctc aagggtggtt atggaaaccc
6421 agccattgat tgcctactac cacaagagtg ggtgcaacac ttctatcaag aagcagcccc
6481 ttcaatgagt gaggtggccc ttgtcagata catcaacccg gatactggtc gggcactgtt
6541 tgaggccaag ctccacagag ctggtttcat gacagtctcg agtaacacca gtgccccggt
6601 ggttgtgcct gccaacggat acttcagatt tgattcttgg gtgaatcagt tctattctct
6661 cgcccccatg ggaactggga atgggcgtag aagggttcaa taatggctgg agcttttgta
6721 gctggtcttg caggggacgt gctcagcaat gggctcagtt cattaatcaa tgcaggtgct
6781 aatgcaataa atcagagggc agaatttgat tttaaccaga aattgcagca aaattctttt
6841 aatcatgata aggagatgtt gcaggctcag atccaggcaa ctaagcagct gcaggcagac
6901 atgatggcta taaaacaagg ggtcttgacc gctggcggct tttcccctgc tgatgcagcc
6961 agaggtgctg tgaacgcgcc catgacacag gcgctggatt ggaatggtac aagatattgg
7021 gcaccaagct ccatgaggac cacatcttat tctggaaaat tcacatcaac cgccccagtg
7081 agacaggccg acttccagca cacccaaagc cggccttcga gtggctcttc cgtgtcttcc
7141 tttgccactc agtcttcaag gccaactctg accacaacca ctggttcatc acacggcaca
7201 gcctcatcaa attcaactcg cagcacaagc ctctcccaat caacggtctc cagagctaca
7261 tctaggactg gcgagtgggt tagagaccaa aatagaaatt tggaacccta catgcatggt
7321 gccttacaga cagcctttgt caccccacct tccagcaggg cgtctgacgg gacagtctca
7381 accgtcccga aaggtgtttt ggactcctgg acacctgcgt ttaacacccg caggcagccg
7441 ctgtttgcac acctccgtaa gaggggggag tcacaagctt agtgaaa
//