Typing tool
|
|
|
|
|
|
Typing tool
|
Complete norovirus genomes
| MK752941 | GII.2 | |
|
|---|---|---|---|
| GII.P16 |
ORF1: 2..5101
ORF2: 5082..6710
ORF3: 6710..7489
LOCUS MK752941 7509 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P16-GII.2/BlackHawk0455
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK752941
VERSION MK752941.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7509)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7509)
AUTHORS Barclay,L., Cannon,J.L., Davis,T., Montmayeur,A.M., Tatusov,R.L.
and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7509
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="BlackHawk0455"
/isolate="Hu/US/2017/GII.P16-GII.2/BlackHawk0455"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="09-Nov-2017"
/note="genotype: GII.P16-GII.2"
gene 2..5101
/gene="ORF1"
CDS 2..5101
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS47654.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQ
PDVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVERGLVLGVHKPPAA
ISMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQDWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILFAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRMRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPDV
EKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGRGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRIMAFRQLAAENKYGLMDTMRVGNQLKGVK
TMEELKQAIRNVTIKRCQIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEE
APKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTKKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVVPAGITEAFGVPIKQIQIHKSGEFCRFRFPKSIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGSPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 2..997
/gene="ORF1"
/product="p48"
mat_peptide 998..2095
/gene="ORF1"
/product="NTPase"
mat_peptide 2096..2626
/gene="ORF1"
/product="p22"
mat_peptide 2627..3025
/gene="ORF1"
/product="VPg"
mat_peptide 3026..3568
/gene="ORF1"
/product="Pro"
mat_peptide 3569..5098
/gene="ORF1"
/product="RdRp"
gene 5082..6710
/gene="ORF2"
CDS 5082..6710
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47655.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPIENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6710..7489
/gene="ORF3"
CDS 6710..7489
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47656.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFTTQSSRPTLTTTT
GSSHGTASSNSTRSTSLSQSTVSRVTSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTASTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 aatgaagatg gcgtctaacg acgctaccgt tgccgttgct tgcaacaaca acaacgacaa
61 agagaaatct tcaggtgaag gcttattcac aaatatgtct tccaccttaa agaaagccct
121 cggggctagg cccaaacagc ctgccccgag agacaaacca caaaaacccc caagaccacc
181 aactcccgag ttggtcaaga ggataccccc tcctccacct aatggcgaag aagaagaaga
241 accagtcatt aggtatgagg ttaagagtgg gatctctggc ctgcccgagc tcacaacagt
301 cccccaaccg gacgtggcca acacagcatt cagtgttcca ccactgagct tgagagaaaa
361 cagggaggcc aaagaaccgc taacaggggc aatattagag atgtgggatg gagagatata
421 ccactatggc ctgtacgtgg agagaggctt agtgttgggt gtgcacaaac cacctgcagc
481 cataagcatg gcaagagtgg agctaacgcc gttgtcattg tactggcgtg tggtgtacac
541 tccccagtac ctcatctccc ctgaaactct caggaggctc aacggagagg cattccctta
601 caccgccttt gacaataact gctatgcctt ttgctgctgg gtgttagacc tcaatgactc
661 gtggcttagc aggaggatgg tacaaagaac aacgggcttc ttcagacctt accaagattg
721 gaacagaaaa cccctgccta ccatggatga ctccaaaatt aagaaggtgg caaatatatt
781 cctatgttca ttgtccacat tattcaccag acccataaaa gacctcatag gaaaaataaa
841 accattaaac atattgaata tcctggcaac gtgtgactgg acttttgccg gaatagtgga
901 gtctctgata ttatttgctg aactcttcgg agttttctgg acacccccag atgtgtctgc
961 tatgatcgcc cccttactcg gggactacga gttgcaaggg ccagaagacc tcgccgtcga
1021 actcgtacct gtggtaatgg gggggattgg tttggtgttg ggattcacca aagagaaaat
1081 tggcaaaatg ttgtcctcag cagcttcaac actcagggct tgcaaagatc ttggtgccta
1141 tggcttagag atactcaaat tggtcatgaa gtggttcttc ccaaagaaag aggaggccaa
1201 tgagctagcc atggtgaggg ccatagagga tgctgtacta gaccttgagg caatagaaaa
1261 taaccacatg acaaccctgt tgaaagacaa agacagcttg gcaacgtaca tgaaaacact
1321 ggacatggag gaggagaaag ccaggaggtt gtccacaaaa tctgcatccc ctgacatagt
1381 tgggacaatc aacgccctgc tggctcgaat agcagcagcc aggtcattag tccacagggc
1441 caaggaagag ctatctagca ggatgaggcc agtggttgtt atgatatctg gcaaaccagg
1501 aataggcaaa actcatctgg ccagggaggt ggcaagaaag gtggcatcca ctctcacagg
1561 ggatcaaaga gtcggactca taccacgaaa cggtgtggac cattgggatg catacaaagg
1621 tgagagagtc gtgctgtggg acgactatgg catgagcaac cccattcatg atgctcttcg
1681 catacaagaa ttggctgaca cgtgtcccct taccttaaat tgtgacagaa ttgaaaataa
1741 gggaaaagtt tttgacagtg aagtcataat aattacaaca aacctcgcca atccagcccc
1801 acttgattat gtcaactttg aggcctgttc caggagaatt gattttctgg tgtacgctga
1861 agcaccagac gtagaaaagg caaaacggga ctttcctggt cagccagata tgtggaagga
1921 cgccttcaag ccagactttt cacacatcaa gctacagctt gcaccccagg gcggctttga
1981 caagaatggc aacaccccac atgggagagg agtgatgaag accctcacta ctggttctct
2041 gattgcccgt gcatcaggcc tactgcatga gaggatggat gaatttgaac tccaaggtcc
2101 cacaatcacc accttcaatt tcgaccggaa cagaatcatg gcattcagac aattggctgc
2161 agaaaacaag tatggattga tggataccat gagagttggc aatcaattaa aaggagtgaa
2221 aaccatggaa gaactcaaac aagcaatcag gaatgtgacc atcaagaggt gccagatcat
2281 ctacggtggt tccacgtatg accttgaatc tgatggcaag ggcaaagttt tggtggaaaa
2341 ggtcaagaac acctctgtac agaccaacaa cgagttggct ggggccctgc accatctcaa
2401 acatgcccga atcaggtact atgtcaaatg tgtgcaagaa gcagtctatt ccatcataca
2461 aattgccggc gctgcgtttg tcaccacacg cattgcacgc cgcatgaaca tacaagaact
2521 ctggtcgaag ccacaactag atcaaaatga atcagagact aaggaagagg cccccaagtc
2581 agaagatgac gagttcatca tatcttctaa ggacatcaag gaggaaggaa agaagggcaa
2641 aaacaaaact ggccgtggca agaaacacac tgcattctcc agcaagggct tgagcgatga
2701 ggagtatgac gagtacaaga ggataagaga agagagaaat gggaagtact ctatagagga
2761 gtatcttcaa gacagagaca ggtactatga ggagctcgcc attgccaagg ccacggaaga
2821 agacttctgt gaagaggagg agatcaaaat ccgtcagaga attttccgtc ccaccaagaa
2881 acaaagaaag gaagagaggg ccacattagg gctagtaaca ggttcagaaa tccgaaaaag
2941 aaaccctgat gacttcaaac ccaaagggaa gctgtgggcc gatgacaaca ggagtgttga
3001 ctacaatgag aaactggact ttgaggcccc cccaagcata tggtctagga ttgtgagctt
3061 tggttctggc tggggcttct gggtgtcacc aagccttttc ataacatcaa ctcatgtagt
3121 ccccgcaggc ataacagaag catttggagt ccccatcaaa caaattcaga tccacaaatc
3181 aggcgaattt tgccgattca gattcccaaa atcaattaga ccagatgtga caggaatgat
3241 cttggaagaa ggtgcgcctg agggcaccgt ggcaactgtg ctcatcaaac gccccaccgg
3301 agagctcatg cctcttgcag ccagaatggg aacacacgca accatgaaaa ttcaaggccg
3361 catggttggc gggcagatgg gtatgttgct cactggatca aatgctaaag gaatggactt
3421 gggaacaact cctggtgact gtggctgtcc ttatatctat aaaaggggca atgactatat
3481 agtcattggg gtgcacactg cagcagcccg tggtggaaac accgtcatct gtgccacaca
3541 gggaagtgag ggtgaggcaa ctcttgaggg tggagatgac aaaggaacat actgtggggc
3601 acccattcta ggccctgggg gttcaccaaa attgagcacc aaaaccaaat tttggaggtc
3661 atcgaacacg ccccttccac cagggacata tgagcctgcc tacctcggtg gccgtgatcc
3721 gcgtgttaag ggtgggcctt ccctgcagca ggtaatgaga gaccaattga agccattcac
3781 tgaacccagg ggcaaacctc caagaccaag tgtattggaa gcagccaagc aaaccatcat
3841 caatgtcctc gaacaaaccc tggaccctcc acaaaaatgg acatacgcac aggcgtgcgc
3901 ctcacttgac aaaaccacct ccagcgggca cccccatcac gtccgaaaga atgaattctg
3961 gaatggtgag accttcactg gtaaactggc agaccaagca tcaaaagcaa acctaatgtt
4021 tgaggaaggg aagcacatga caccagtata cacagcagca ctcaaggacg agctagtcaa
4081 gaccgagaaa atctatggaa agattaagaa gagactgctc tggggctctg acttgtccac
4141 catgatccgg tgcgctaggt catttggtgg gctcatggac gagatgaagg cacactgcat
4201 atcactccca gtccgagttg gcatgaatat gaatgaagat ggcccaataa tatttgaaaa
4261 gcattccaga tacaaatatc actatgatgc agactactct cgttgggatt caacacaaca
4321 gagggcagta ctagcagcag ccttggaaat catggtcaga ttctctgcag aaccacaatt
4381 ggcacaaata gtcgctgagg atctgctggc tcctagtgta gtagatgtag gagactttaa
4441 aattacaata aatgaagggc tcccttctgg tgtgccatgc acttctcaat ggaactccat
4501 cgcacactgg ctgctaactc tctgtgcctt gtctgaagtc accaaactgt cccctgacat
4561 tatacaggca aattccatgt tctcatttta cggtgatgac gagattgtca gcaccgatat
4621 aaaattggac cctgaacagt taaccgccaa attgaaggag tacggcctga aaccaacccg
4681 cccggacaaa accgagggac ccctgattat cagtgaagat ttgaacggtc ttactttcct
4741 ccgaagaacg gtgactcgtg acccagctgg ctggtttgga aaactggacc aaagctcaat
4801 tttgaggcag atgtactgga ctagaggacc aaatcatgaa gaccccaatg agacaatgat
4861 accccattcc caaagaccca tacaactcat ggcactgctt ggtgaagcct ctcttcacgg
4921 accctctttc tacagtaaaa tcagtaaatt ggtcataact gaactcaaag aaggtgggat
4981 ggacttttac gtgccaaggc aggaacccat gttcaggtgg atgaggtttt ctgacttgag
5041 cacgtgggag ggcgatcgca atctggctcc caattttgtg aatgaagatg gcgtcgaatg
5101 acgccgctcc atctactgat ggtgcagccg gcctcgtgcc agaaagtaac aatgaggtca
5161 tggctcttga acccgtggct ggtgccgctt tggcagcccc ggtcaccggt caaacaaata
5221 ttatagaccc ttggattaga gcaaattttg tccaggcccc taatggtgaa tttacagtct
5281 ctccccgaaa tgcccctggt gaagtgctac tgaatctaga gttgggtcca gaattaaatc
5341 cttatctggc acatttagca agaatgtaca atgggtatgc cggtgggatg gaggtgcagg
5401 tcatgttggc tgggaacgcg ttcacagccg gcaagttggt cttcgccgcc gtgccacccc
5461 acttcccgat tgaaaacctt agcccacagc aaatcaccat gttccctcat gtgatcatag
5521 atgtgagaac cttggaacct gttttattac cactccctga tgttaggaat aacttcttcc
5581 attataatca gaaagatgat cccaagatga gaattgtggc tatgctttat acccccctca
5641 ggtccaatgg ttcaggtgat gatgtgttta cagtttcctg tagagtgttg actagacctt
5701 cccctgactt tgatttcaca tacctggtgc caccaacagt ggagtctaaa acaaagccat
5761 tcaccctccc aatcctcaca cttggggaac tttccaattc taggttccca gtgtccatag
5821 accagatgta caccagccct aatgaagtta tatcagtgca gtgtcaaaat ggtaggtgca
5881 cactagacgg ggagctccaa gggacaacac aactccaagt cagtggcatt tgtgctttca
5941 aaggtgaagt gaccgctcac ttgcatgaca atgatcatct atataatgtt accatcacaa
6001 acttgaatgg gtcccctttt gatccctccg aggatatccc tgcccctctg ggtgtgcctg
6061 acttccaggg aagggttttt ggtatcatct cccaaagaga caaacacaac agtcctgggc
6121 ataatgaacc agcaaacagg ggacacgacg ctgtggtccc tacttacaca gcacagtata
6181 ctccaaaact gggacaaatt caaattggca cgtggcaaac tgacgacctt acagtcaacc
6241 aaccagtcaa attcacccca gttggactca atgatactga acattttaac caatgggtgg
6301 tccctaggta tgctggtgcc ctaaacctca atacaaacct tgccccttct gttgctccag
6361 tatttccagg agagcgcctg ctcttcttca gatcatacat tcccctcaag ggcggttatg
6421 gaaacccagc cattgattgc ctactaccac aagagtgggt gcaacacttc tatcaggaag
6481 cagccccttc aatgagtgag gtggccctcg tcagatacat caacccggac actggtcggg
6541 cactgtttga ggccaagctc cacagagctg gtttcatgac agtctcgagc aacaccagtg
6601 ccccggtggt tgtgcctgcc aacggatact tcagatttga ttcttgggta aaccaatttt
6661 attctctcgc ccccatggga actgggaatg ggcgtagaag ggttcaataa tggctggagc
6721 ttttgtagct ggtcttgcag gggacgtgct cagcaatggg cttagttcat taatcaatgc
6781 aggtgctaat gcaataaatc agagggcaga atttgatttt aatcagaaat tgcaacaaaa
6841 ttcttttaat catgataagg agatgttgca ggctcagatt caggcaacta agcagctgca
6901 ggcagacatg atggccataa aacaaggggt cttgaccgct ggcggctttt cccctgctga
6961 tgcagccaga ggtgctgtga acgcgcccat gacacaggcg ctggattgga atggcacaag
7021 gtattgggca ccaaactcca tgaggaccac atcttattct ggaaaattca catcaaccgc
7081 cccagtgagg caggctgact tccaacacac ccaaagccgg ccttcgagtg gctcctctgt
7141 gtcttccttt accactcagt cttcaaggcc aactctgacc acaaccactg gttcctcaca
7201 tggcacagcc tcatcaaatt caactcgcag cacaagcctc tcccaatcaa cggtctccag
7261 agttacgtct aggactggtg agtgggttag agatcaaaat agaaatttgg aaccctacat
7321 gcatggtgcc ttacagacag cctttgtcac cccaccttcc agcagggcat ctgacgggac
7381 agcctcaacc gtcccgaaag gtgttttgga ctcctggaca cctgcgttta acacccgcag
7441 gcagccgctt tttgcacacc tccgtaagag gggggagtca caagcttagt gaaaaggtga
7501 aaatttatt
//