Typing tool
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Typing tool
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Complete norovirus genomes
| MK752939 | GII.2 | |
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| GII.P16 |
ORF1: 4..5103
ORF2: 5084..6712
ORF3: 6712..7491
LOCUS MK752939 7498 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2017/GII.P16-GII.2/Pierce0448
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK752939
VERSION MK752939.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7498)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7498)
AUTHORS Barclay,L., Cannon,J.L., Davis,T., Montmayeur,A.M., Tatusov,R.L.
and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (04-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7498
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Pierce0448"
/isolate="Hu/US/2017/GII.P16-GII.2/Pierce0448"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="23-Aug-2017"
/note="genotype: GII.P16-GII.2"
gene 4..5103
/gene="ORF1"
CDS 4..5103
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBS47648.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQ
PDVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
ISMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEV
EKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRIAAFRQLAAENKYGLVDTMKVGNQLKGVK
TMEELKQAIRNVTIKRCQIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEE
APKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPAGITEAFGVSIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 4..999
/gene="ORF1"
/product="p48"
mat_peptide 1000..2097
/gene="ORF1"
/product="NTPase"
mat_peptide 2098..2628
/gene="ORF1"
/product="p22"
mat_peptide 2629..3027
/gene="ORF1"
/product="VPg"
mat_peptide 3028..3570
/gene="ORF1"
/product="Pro"
mat_peptide 3571..5100
/gene="ORF1"
/product="RdRp"
gene 5084..6712
/gene="ORF2"
CDS 5084..6712
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBS47649.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEAMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEIISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6712..7491
/gene="ORF3"
CDS 6712..7491
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBS47650.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTASSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 tgaatgaaga tggcgtctaa cgacgctacc gttgccgttg cttgcaacaa caacaacgac
61 aaagaaaaat cttcaggtga aggcttattc acaaatatgt cttccacctt aaagaaagcc
121 ctcggggcta ggcccaaaca gcctgccccg agagacaaac cacaaaagcc cccaagacca
181 ccaactcccg agttggtcaa gaggataccc cctcctccac ctaacggcga agaagaagaa
241 gagccagtca ttaggtatga ggtcaagagt gggatctctg gcctgcccga gctcacaaca
301 gtcccccaac cggacgtggc caacacagca ttcagtgttc caccactgag cttgagagaa
361 aacagggagg ccaaggagcc gctaacaggg gcaatattag agatgtggga tggagagata
421 taccactatg gcctgtacgt ggagaaaggc ttagtgttgg gtgtgcacaa accacctgca
481 gccataagca tggcaagagt ggagctgacg ccgttgtcat tgtactggcg tgtggtgtac
541 actccccaat acctcatctc ccctgaaacc ctcaggaggc tcaacggaga ggcattccct
601 tacaccgcct ttgacaacaa ctgctatgcc ttttgctgct gggtgttaga tctcaatgac
661 tcatggctta gcaggaggat ggtacaaaga acaacgggct tcttcagacc ttaccaagag
721 tggaacagaa aacccctgcc taccatggat gactccaaaa ttaagaaggt agcaaatata
781 ttcctatgtt cattgtccac attattcacc agacccataa aagacctcat aggaaaaatt
841 aaaccattga acatattgaa tatcctggca acgtgtgact ggacttttgc cggaatagtg
901 gagtctctga tattacttgc tgaactcttc ggagttttct ggacaccccc agatgtgtct
961 gctatgatcg ctcccttact cggggactac gagttgcaag ggccagaaga cctcgccgtt
1021 gaactcgtac ctgtggtaat gggggggatt ggtttggtgt tgggattcac caaagagaaa
1081 attggcaaaa tgttgtcctc agcagcatca acactcaggg cttgcaaaga tcttggtgcc
1141 tatggcttag agatactcaa attggtcatg aagtggttct tcccaaagaa agaggaggcc
1201 aatgagctag ctatggtgag ggccatagag gatgctgtac tagaccttga ggcaatagaa
1261 aataaccaca tgacaaccct gttgaaagac aaagacagct tagcaacata catgaaaaca
1321 ctggacatgg aggaggagaa agccaggagg ttgtccacaa aatctgcatc ccctgacata
1381 gttgggacaa tcaacgccct gctggctcga atagcagcgg ccaggtcatt agtccacagg
1441 gccaaggaag agctatctag taggataagg ccagtagttg ttatgatatc tggcaagcca
1501 ggaataggca aaactcatct ggccagggag gtggcaagaa aggtggcatc cactctcaca
1561 ggggatcaaa gagtcggact cataccacga aacggtgtgg accattggga tgcatacaaa
1621 ggtgagagag tcgtgctgtg ggacgactat ggcatgagta accctattca tgatgctctt
1681 cgcatacaag aattggctga tacgtgtccc cttaccttaa attgtgacag aattgaaaat
1741 aagggaaaag tttttgacag tgaagtcata ataattacaa caaaccttgc caatccagcc
1801 ccacttgatt atgtcaactt tgaggcctgt tccaggagaa ttgacttcct ggtgtacgct
1861 gaggcaccag aagtagaaaa ggcaaaacgg gactttcctg gtcagccaga tatgtggaag
1921 gacgccttca agccggactt ttcacacatc aagctacagc ttgcacccca gggcggcttt
1981 gacaagaatg gcaacacccc acatgggaaa ggagtaatga agaccctcac taccggttct
2041 ctgattgccc gtgcatcagg cctactgcat gagaggatgg atgaatttga actccaaggc
2101 cccacaatca ccaccttcaa tttcgaccga aacagaatcg cggcattcag acaattagct
2161 gcagaaaaca agtatggatt ggtggatacc atgaaagttg gcaatcagtt aaaaggagtg
2221 aaaaccatgg aagaactcaa acaagcaatc aggaatgtga ccatcaagag gtgccagatc
2281 atctacggtg gttccacgta tgaccttgaa tctgatggca agggcaaagt tttggtggaa
2341 aaagtcaaga acacctctgt acagaccaat aacgagttgg ctggggccct gcaccatctc
2401 aaacatgccc gaatcaggta ctatgtcaaa tgtgtgcaag aagcagtcta ttccatcata
2461 caaattgccg gcgctgcgtt tgtcaccacg cgcattgcac gccgcatgaa catacaagaa
2521 ctctggtcga agccacaact agatcaaaat gaatcagaga ctaaggaaga ggcccccaag
2581 tcagaagatg acgagttcat catatcttct aaggacatca aggaggaagg aaagaagggc
2641 aaaaacaaaa ctggccgtgg caagaaacac actgcattct ccagcaaggg cttgagcgat
2701 gaggagtatg acgagtacaa gaggataaga gaagagagaa atgggaagta ctctatagag
2761 gagtatcttc aagacagaga caggtactat gaggagctcg ccattgccaa ggccacggaa
2821 gaagacttct gtgaagagga ggagatcaaa atccgtcaga gaattttccg tcccaccagg
2881 aaacaaagaa aggaagagag ggccacatta gggctagtaa caggttcaga aatcagaaaa
2941 agaaaccctg atgacttcaa acccaaaggg aagctatggg ccgatgacaa caggagtgtt
3001 gactacaatg agaaactgga ctttgaggcc cccccaagca tatggtctag gattgtgagc
3061 tttggctctg gctggggctt ctgggtgtca ccaagccttt tcataacatc aactcatgta
3121 atccccgcag gcataacaga agcatttgga gtctccatca aacaaattca gatccacaaa
3181 tcgggcgaat tttgccgatt cagattccca aaaccaatta gaccagatgt gacaggaatg
3241 atcttggaag aaggtgcgcc tgagggcacc gtggcaactg tgctcatcaa acgccccacc
3301 ggagagctca tgcctcttgc agccagaatg ggaacacacg caaccatgaa aattcaaggc
3361 cgcatggttg gcggacagat gggtatgttg ctcactggat caaatgctaa aggaatggac
3421 ttgggaacaa ctcctggtga ctgtggctgt ccttacatct ataaaagggg caatgactat
3481 atagtcattg gggtgcacac tgcagcagcc cgtggtggaa acactgtcat ctgtgccaca
3541 cagggaagtg agggtgaggc aactcttgag ggtggagatg acaaaggaac atactgtggg
3601 gcacccattc taggccctgg gggtgcacca aaattgagca ccaaaaccaa attttggagg
3661 tcatcgaaca cgcccctccc accagggaca tatgagcctg cctacctcgg tggccgtgat
3721 ccgcgtgtta agggtgggcc ttccctgcag caggtgatga gagaccagtt gaagccattc
3781 actgaaccca ggggcaaacc tccaagacca agtgtattgg aagcagccaa acaaaccatc
3841 atcaatgtcc tcgaacaaac cctggaccct ccacaaaaat ggacatacgc acaggcttgt
3901 gcctcacttg acaaaaccac ctccagcggg cacccccatc acgtccgaaa gaatgaattc
3961 tggaatggtg agaccttcac tggtaaactg gcagaccaag catcaaaagc aaacctaatg
4021 tttgaggaag ggaaacacat gacaccagtg tacacagcag cactcaagga cgagctagtc
4081 aagactgaga aaatctatgg aaagatcaag aagagactgc tctggggctc tgacttgtcc
4141 accatgatcc ggtgcgctag gtcatttggt gggcttatgg acgagatgaa ggcacactgc
4201 atatcactcc cagtccgagt tggcatgaat atgaatgaag atggcccaat aatatttgag
4261 aaacattcca gatacaaata tcactatgat gcagactact ctcgttggga ttcaacacaa
4321 cagagggcag ttctagcagc agccttggaa atcatggtca gattctctgc agaaccacaa
4381 ttggcacaaa tagtcgctga ggatctgctg gcccctagtg tagtagatgt aggagacttt
4441 aaaattacaa taaatgaagg gctcccttct ggtgtgccat gcacttctca atggaactcc
4501 atcgcacact ggctgctaac tctctgtgcc ttgtctgaag tcaccaaact gtcccctgac
4561 attatacagg caaattccat gttctcattt tacggtgatg acgagattgt cagtaccgac
4621 ataaaattgg accctgaaca gttaaccgcc aaattgaagg agtacggcct gaaaccaacc
4681 cgcccagaca aaaccgaggg acccctgatt atcagtgaag atttgaacgg tctcactttc
4741 ctccgaagga cggtgactcg tgacccagct ggctggtttg gaaaactgga ccaaagctca
4801 attttgaggc agatgtactg gactagagga ccaaatcatg aagaccccaa tgagacaatg
4861 ataccccatt cccaaagacc catacagctc atggcactgc ttggtgaagc ctctcttcac
4921 ggaccctctt tctacagtaa aatcagtaaa ttggtcataa ctgaactcaa agaaggtggg
4981 atggactttt acgtgccaag gcaggaaccc atgttcaggt ggatgaggtt ttctgacttg
5041 agcacgtggg agggcgatcg caatctggct cccaattttg tgaatgaaga tggcgtcgaa
5101 tgacgccgct ccatctactg atggtgcagc cggcctcgtg ccagaaagta acaatgaggc
5161 catggctctt gaacccgtgg ctggtgccgc cttggcagcc ccggtcaccg gtcaaacaaa
5221 tattatagac ccttggatta gagcaaattt tgtccaggcc cccaatggtg aatttacagt
5281 ctctccccga aatgcccctg gtgaagtgct actgaatcta gaattgggtc cagaattaaa
5341 tccttatctg gcacatttag caagaatgta caatgggtat gccggtggga tggaggtgca
5401 ggtcatgttg gctgggaacg cgttcacagc cggcaagttg gtcttcgccg ccgtgccacc
5461 ccacttcccg gttgaaaacc ttagcccaca gcaaatcacc atgttccctc atgtgatcat
5521 agatgtgaga accttggaac ctgttttatt accactccct gatgttagga ataacttctt
5581 ccattataac cagaaagatg atcccaagat gagaattgtg gctatgcttt atacccccct
5641 caggtctaat ggttcaggtg atgatgtgtt tacagtctcc tgtagagtgt tgactagacc
5701 ttcccctgac tttgacttca catacctggt gccaccaaca gtggagtcta aaacaaagcc
5761 attcaccctc ccaatcctca cacttgggga actttccaat tctaggttcc cagtgtccat
5821 agaccagatg tacaccagcc ccaatgaaat tatatcagtg cagtgtcaaa atggtaggtg
5881 cacactggac ggggagctcc aagggacaac acaactccaa gtcagtggca tttgtgcttt
5941 caaaggtgag gtgaccgccc acttgcatga caatgatcac ctatataatg tcaccatcac
6001 aaacttgaat gggtcccctt ttgatccctc cgaggatatc cctgcccctt tgggtgtgcc
6061 tgacttccag ggaagggttt ttggtatcat ctcccaaaga gataaacaca atagtcctgg
6121 gcataatgaa ccagcaaaca ggggacacga cgctgtggtc cctacttaca cagcacagta
6181 cactccaaaa cttggacaaa ttcaaattgg cacatggcaa actgacgacc ttacagtcaa
6241 ccaaccagtc aaattcaccc cagttggact caatgacact gaacacttta accaatgggt
6301 ggtccctagg tatgctggtg ccctaaacct caatacaaac cttgcccctt ctgttgctcc
6361 agtatttcca ggagagcgcc tgctcttctt cagatcatac attcccctca agggcggtta
6421 tggaaaccca gccattgatt gcttactacc acaagagtgg gtgcaacact tctatcagga
6481 agcagcccct tcaatgagtg aggtggccct cgtcagatac atcaacccgg acactggtcg
6541 ggcactgttt gaggccaagc tccacagagc tggtttcatg acagtctcga gcaacaccag
6601 tgccccggtg gttgtgcctg ccaacgggta cttcagattt gattcttggg tgaaccagtt
6661 ttattctctc gcccccatgg gaactgggaa tgggcgtaga agggttcaat aatggctgga
6721 gcttttgtag ctggtcttgc aggggacgtg ctcagcaatg ggcttagttc attaatcaat
6781 gcaggtgcta atgcaataaa tcagagggca gaattcgatt ttaaccaaaa attgcagcaa
6841 aattctttta atcatgataa ggagatgttg caggctcaga ttcaggcaac taagcagctg
6901 caggcagaca tgatggctat aaaacaaggg gtcttgaccg ctggcggctt ttcccctgct
6961 gatgcagcca gaggtgctgt aaacgcgccc atgacacagg cgctggattg gaatggtaca
7021 aggtattggg caccaaactc catgaggacc acatcttatt ctggaaaatt cacatcaacc
7081 gccccagtga ggcaggctga cttccagcac acccaaagcc ggccttcgag tggctcctct
7141 gtgtcttcct ttgccactca gtcttcaagg ccaactttga ccacaaccac tggttcctca
7201 catggcacag cctcatcaaa ttcaactcgc agcacaagcc tctcccaatc aacggtctcc
7261 agagctacat ctaggactgg tgagtgggtt agagatcaaa atagaaattt ggaaccctac
7321 atgcatggtg ccttacagac agcctttgtc accccacctt ccagcagggc atctgacggg
7381 acagtctcaa ccgtccctaa aggtgttttg gactcctgga cacctgcgtt taacacccgc
7441 aggcagccgc tttttgcaca cctccgtaag aggggggagt cacaagctta gtgaaaag
//