Typing tool
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Typing tool
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Complete norovirus genomes
| MK729086 | GII.2 | |
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| GII.P2 |
ORF1: 5..5104
ORF2: 5085..6713
ORF3: 6713..7492
LOCUS MK729086 7496 bp RNA linear VRL 08-APR-2019
DEFINITION Norovirus GII isolate Hu/Guangzhou/GZ2015-L335/CHN/2015
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MK729086
VERSION MK729086.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7496)
AUTHORS Xue,L., Gao,J., Cai,W., Zhang,L., Zuo,Y., Zhang,J. and Wu,Q.
TITLE Comparative molecular evolution of the major and minor capsid
proteins VP1/VP2 in human norovirus genotype GII.2
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7496)
AUTHORS Xue,L., Gao,J., Cai,W., Zhang,L., Zuo,Y., Zhang,J. and Wu,Q.
TITLE Direct Submission
JOURNAL Submitted (02-APR-2019) State Key Laboratory of Applied
Microbiology Southern China, Guangdong Institute of Microbiology,
Xianlie Zhong Road, Guangzhou, Guangdong 510070, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7496
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/Guangzhou/GZ2015-L335/CHN/2015"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="China"
/collection_date="20-Jan-2015"
/note="genotype: GII.P2|GII.2"
gene 5..5104
/gene="ORF1"
CDS 5..5104
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBR54579.1"
/translation="MKMASNDASAAAAVNSNNDNTKSSNDGMLNNMAVTLKRALGARP
KQPVPREKPPRPPRPPTPELIKRIPPPPPNDGDEPTVMFSTVGGVSGLPELTTVGQPP
EANTAFSVPPLSQRENRDAKEPLTGTILEMWDGEIYHYGLYVEKGLVLGVHKPPAAIS
IAKVELTPLSLYWRPVYTPQYLISPDTLRKLHGELFPYTAFENNCYAFCCWVLDLNDS
WLSRRMISRTTGFFRPYQEWNRKPLPTMDDSKLKKVANIVLCALSSLFTRPIKDIIGK
LKPLNILNILASCDWTFAGIVESLILFAELFDVFWTPPDVSAMIAPLLGDYELQGPED
IAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKDEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKNSLAAYMKTLDMEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGKPGIGKTHLAREL
AKKIASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLVNPAPLDYVNFEACSRRIDFLVYADAPEVEK
AKRDFPGQPDMWKDAYRPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTASSLVARA
SGLLHERLDEYELQGPSLSTFNFDRNKIAAFRQLAAENKYGLVDTMKVGNQLRNVTTM
DELKKAIKNIMIRKCQIVYGGNTYTLESDGKGKVVVERVQNASVQINNEIAGAVHHLR
CARIRYYVKCVQEAIYSLLQIAGTVFVTSRIVSRMNIQNFWSRPLTEDVDEATTKEGC
PKPREEEEFIVSSDDIKPEGKKGKNKSGRGKKHTAFSSKGLSDEEYEEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERANLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNERISFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGITEAFGVPIRQVQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEG
TVATILIKRTTGELMPLAARMGTHATMRIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGNAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPQKWTYAQACASLDKTTSSGFPHHVRKNEHW
NGESFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKVYGKIKKRLLWGSDL
ATMVRCARSFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLAAAMEIMVKFSAEPQLAQIVAEDLLSPSVVDVGDFKISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIVQANSLFSFYGDDEIVSTDIKLDPEKLTGKLR
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTKGP
NHEDPFESMIPHSQRPIQLMSLLGEAALHEPSFYSKISKLVISELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSLVNEDGVE"
mat_peptide 5..994
/gene="ORF1"
/product="p48"
mat_peptide 995..2092
/gene="ORF1"
/product="NTPase"
mat_peptide 2093..2629
/gene="ORF1"
/product="p22"
mat_peptide 2630..3028
/gene="ORF1"
/product="VPg"
mat_peptide 3029..3571
/gene="ORF1"
/product="Pro"
mat_peptide 3572..5101
/gene="ORF1"
/product="RdRp"
gene 5085..6713
/gene="ORF2"
CDS 5085..6713
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBR54580.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHSEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6713..7492
/gene="ORF3"
CDS 6713..7492
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBR54581.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQRLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPGSMRTTSYSGRFTSTAPARQADFQHTQSRPSSGSSVSSFATQSSRPTLATTT
GSSHGTASSNSTRSTNLSQSTVSRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc tgctgccgct gctgttaaca gcaacaacga
61 caacacaaaa tcttcgaatg acggaatgct taacaacatg gccgtcaccc ttaaacgagc
121 ccttggggcc cggcccaaac agccggtccc gagggagaaa cccccaagac cccctagacc
181 accaacacca gaattgatca aaagaatccc ccccccacca cccaatgatg gggacgaacc
241 aaccgtgatg ttcagcactg taggtggtgt gtctggccta cctgagctta caacagttgg
301 tcaaccacct gaagctaaca cggcctttag tgtgcctccc ctcagccaaa gggagaatag
361 ggacgctaag gaaccgttaa ctggaaccat tctggaaatg tgggatgggg agatctatca
421 ttatggtctg tatgtggaaa aagggcttgt gttaggcgtg cacaagccgc cggctgccat
481 cagcatagcc aaagtggagt taacgcccct ctcactgtac tggaggcctg tttacacgcc
541 tcagtacctt atatctcctg acaccttgag gaaactccat ggtgaattat ttccctacac
601 agcctttgaa aacaattgtt atgccttctg ctgttgggtt ttggacctta acgattcatg
661 gctaagcaga aggatgatta gtaggactac tggctttttc aggccctacc aagagtggaa
721 caggaagccc ctcccaacta tggatgactc aaaattgaag aaggttgcaa acatcgttct
781 gtgtgcattg tcatcactgt tcactagacc cattaaggac ataattggca aacttaaacc
841 cctcaacatc ctaaacatcc tggcttcatg cgactggacc tttgctggca tagtagagtc
901 actaatcctc tttgctgaac tctttgatgt gttctggaca cccccagatg tgtctgcaat
961 gatcgcacct ctcctcggtg actacgagct gcaaggcccc gaagacatcg ctgtggagct
1021 cgtgcccgtt gttatgggtg ggataggctt ggtgttggga ttcaccaaag agaaaatagg
1081 caagatgctc tcctctgcag cgtcaactct gagggcttgt aaagatcttg gagcctacgg
1141 attggagatc ctgaaactag tcatgaaatg gtttttccca aagaaggatg aggccaatga
1201 actggctatg gttagagcca ttgaagacgc tgtgttagac ttggaggcca ttgagaacaa
1261 ccacatgacc actctattga aagacaagaa cagccttgca gcctacatga agaccctgga
1321 catggaagag gaaaaagcta gaaagctatc caccaaatca gcctcccccg acattgtggg
1381 caccataaac gccctgctgg ctaggatcgc tgccgcacgt tccttggttc atagggccaa
1441 ggaagagctc tccagcagac caaggccagt cgtcctgatg atctccggca aaccagggat
1501 aggaaagacc catttggcca gagaactggc aaagaaaatt gcctcaacac tcacaggaga
1561 ccaaagggtg ggcctcatcc cacggaatgg agttgaccat tgggacgcct acaaaggaga
1621 gagagtggtg ctctgggatg actatgggat gagcaacccc attcacgatg cgctgaggtt
1681 gcaggaattg gcagacacat gtccactaac tctgaattgt gacaggattg aaaacaaggg
1741 gaaagtcttc gacagcgacg caatcataat caccaccaat ttggtcaatc ccgcgccgct
1801 ggattatgtc aactttgaag cctgctccag acgtatagac ttccttgtgt atgctgatgc
1861 cccagaagtc gagaaagcaa agcgggactt ccccggtcaa ccggacatgt ggaaggacgc
1921 ctatcgccct gacttctcac atattaaatt gcaacttgca ccacaaggtg ggttcgacaa
1981 gaatggcaac accccacatg gtaaaggagt aatgaagact ctcactgcca gttcactggt
2041 tgcgcgtgcc tctggtctct tgcatgagag attagatgag tacgagttac agggtccgtc
2101 cctttcaacc ttcaactttg accgcaacaa aattgcagcg ttcagacaac tcgccgccga
2161 aaacaagtat ggtctagtgg acacgatgaa ggtgggcaac cagctcagaa atgtcacgac
2221 catggatgag cttaagaagg ctatcaaaaa catcatgatc aggaagtgcc agatagtcta
2281 tggtggcaac acttacacgc ttgaatctga tggcaagggt aaggttgtag ttgagagggt
2341 gcagaacgcc agcgtgcaaa tcaacaatga gatcgctggt gcagtacatc accttagatg
2401 tgccaggata aggtattatg tcaagtgtgt ccaagaggcc atctactcac tcctccaaat
2461 cgccggcacg gtgtttgtca cttcacgcat cgtaagccgc atgaacatcc aaaatttttg
2521 gtccagacca ttaactgaag atgtagatga ggccaccacg aaagaggggt gccctaaacc
2581 tagggaagaa gaggagttta tcgtctcttc agatgatatc aagccagagg gcaagaaagg
2641 taaaaacaag agtggccggg gcaagaaaca cacggcattc tcaagtaaag gtctcagtga
2701 tgaggaatat gaagagtaca agaggatcag agaggagagg aatggcaagt actccataga
2761 ggaataccta caggacagag acaaatacta tgaagaggtg gccattgcca gggcaactga
2821 agaagatttc tgcgaagaag aagaggttaa gattcgtcag aggatcttca ggccaacaag
2881 aaaacaacgc aaggaagaaa gagccaacct tggcctcgtc accggatctg agatcaggaa
2941 aaggaaccca gatgacttca aaccaaaagg gaagttgtgg gccgacgatg acaggagcgt
3001 cgactacaat gaaagaatca gctttgaggc cccaccaagc atttggtcta gaattgtcaa
3061 ctttggttct ggatgggggt tttgggtgtc gcccagtctt ttcataacat caacacatgt
3121 cataccccaa ggcataactg aggcctttgg tgtacccata aggcaggtgc aaatacacaa
3181 atcgggcgaa ttctgtcgac tgagattccc aaaacccatc aggacagatg tatcaggtat
3241 gatactggag gagggagcgc ctgaaggcac tgttgccacc atactcatca aaagaaccac
3301 tggagagctg atgcctctcg cagcaagaat gggcacccac gcgactatga gaatacaagg
3361 gcgcacagtg ggcggccaga tggggatgct gcttactggg tccaacgcaa agagcatgga
3421 tcttggcacc acgcccggtg actgtgggtg cccctacatt tacaaaaggg gcaatgacta
3481 catagtcatt ggagttcaca cagcagccgc tcgtggcgga aacacagtca tctgcgccac
3541 gcaaggcagt gaaggtgagg ccacactcga gggtggtgac aataaaggaa catactgcgg
3601 ggcaccaatc ctaggccccg ggaatgcccc aaagctgagc actaaaacca agttctggag
3661 gtcctccaca acaccactcc cacccggcac gtatgagccg gcatatctgg gaggaaaaga
3721 cccccgagtc aaaggtggac catctctgca acaagttatg cgagaccaac tgaaaccatt
3781 cactgaaccc cgtggtaagc caccaaaacc aagtgtcctt gaagctgcta aaaagacaat
3841 tatcaatgtg ctagaacaaa caatagatcc cccacaaaaa tggacgtacg cacaagcgtg
3901 cgcgtctctc gacaaaacca catctagtgg gttcccccac cacgtgcgca aaaacgagca
3961 ctggaatggg gaatctttca caggaaaatt ggctgaccag gcgtcaaaag caaacctaat
4021 gtttgaagag gggaagcaca tgaccccagt ttacacagct gcccttaagg atgagctggt
4081 caaaactgag aaagtgtatg ggaaaataaa gaagaggttg ctttggggct ctgatctggc
4141 caccatggtg cggtgcgcac gctcctttgg cggtttgatg gacgagctca aggcccactg
4201 tgtgacactt ccgataaggg ttggcatgaa catgaatgaa gatggaccaa taatctttga
4261 gaaacactcc agatataggt accactatga tgcagactat tccaggtggg attcaacaca
4321 gcagagagcc gttctggccg cggccatgga gattatggtt aaattctcag cagaaccaca
4381 actagcccaa atagttgcag aggatctatt gtcgcctagt gtagttgacg tgggcgactt
4441 caaaatttcc atcaatgaag ggttgccatc gggtgtcccc tgcacctctc aatggaactc
4501 catcgcacat tggctcctta ctttgtgtgc cctttctgaa gttacagacc tctctcctga
4561 cattgtacag gccaactccc tcttctcctt ctatggagat gatgaaattg tgagcacaga
4621 tattaaatta gatccagaaa agctgacggg gaagttgaga gaatatggtc tcaaacctac
4681 tcgtcctgac aaaactgagg gccccctgat cattagtgag gatctgaatg gcctgacttt
4741 cctgaggaga accgtcaccc gcgaccctgc ggggtggttt ggcaaactgg accaaagctc
4801 catacttagg caattgtatt ggaccaaagg ccccaatcat gaagacccct ttgagtcaat
4861 gattccacac tcccagagac ccatacaact catgtcactt ttgggcgagg cagcactgca
4921 tgaaccatca ttttacagca agatcagcaa gcttgtaata tccgaattga aagaaggtgg
4981 aatggatttt tacgtgccca ggcaagaacc tatgtttagg tggatgaggt tctcggattt
5041 gagcacgtgg gagggcgatc gcaatcttgc tcccagtctt gtgaatgaag atggcgtcga
5101 atgacgccgc tccatctact gatggtgcag ccggcctcgt gccagaaagt aataatgagg
5161 tcatggctct tgaacccgtg gctggtgccg ctttggcagc ccctgtcact ggtcaaacaa
5221 atattataga cccttggatt agagcaaatt ttgtccaggc ccccaatggt gaatttacag
5281 tttctccccg taatgcccct ggtgaagtgc tactgaatct ggagttgggt ccagaattaa
5341 atccttatct ggcacactta gcaagaatgt acaacgggta cgccggtggg atggaggtgc
5401 aggtcatgct ggctgggaac gcgttcacag ccggcaagtt ggtcttcgcc gccgtgccac
5461 ctcacttccc ggttgaaaac cttagcccac aacaaattac catgttccct catgtgatta
5521 tagatgtaag gactttggaa cctgttttat taccactccc tgatgttaga aataatttct
5581 tccattacaa tcagaaagat gaccccaaga tgagaattgt ggctatgctt tatacccccc
5641 ttaggtctaa tggctcaggt gatgatgtgt ttacagtctc ctgtagggtg ttaactagac
5701 cctctcctga tttcgacttc acatatctgg tgccaccaac agtggagtct aaaacaaaac
5761 cattcaccct cccaatcctc acacttgggg aactttccaa ttctagattc ccagtgtcta
5821 tagaccagat gtacaccagc cctaatgaag ttatatcagt gcagtgtcaa aatggtaggt
5881 gcacattgga cggggagctc caaggaacaa cacaacttca agtcagtggc atttgtgctt
5941 tcaaggggga agtgaccgct cacttgcatg ataatgatca cctatacaat gtcaccatca
6001 caaatttgaa tggatcccct tttgatccct ctgaggacat ccctgctcct ctgggcgtac
6061 ctgacttcca gggaagggtt tttggtatta tctcccaaag agacaaacac aatagccctg
6121 gacatagtga accagcaaac aggggacacg atgctgtggt ccccacttac acagcacagt
6181 acactccaaa attgggtcag attcaaattg gcacatggca gaccgacgat ctcactgtca
6241 accaaccagt caaattcact ccagttggac tcaatgacac tgaacatttc aaccaatggg
6301 tggtccccag atatgctggt gccctaaacc tcaatacaaa tcttgcccct tctgttgctc
6361 cagtgtttcc aggggagcgc ctactctttt tcagatcata catccctctc aagggtggtt
6421 atggaaaccc agccattgat tgcctactac cacaggagtg ggtgcaacac ttctatcagg
6481 aagcagcccc ttcaatgagt gaggtggccc ttgtcagata catcaacccg gacactggtc
6541 gggcactgtt tgaggccaag ctccacagag ctggtttcat gacagtctca agtaacacca
6601 gtgccccggt ggttgtgcct gccaatgggt acttcagatt tgattcttgg gtgaaccaat
6661 tctattctct cgcccccatg ggaactggaa atgggcgtag aagggttcaa taatggctgg
6721 agcttttgta gctggtcttg caggggacgt gctcagcaat gggctcagtt cattaattaa
6781 tgcaggtgct aatgcaataa atcagagggc agaatttgat tttaatcaga gattacagca
6841 aaattctttc aatcatgata aggagatgtt gcaggctcag attcaggcaa ctaagcagct
6901 acaagcagac atgatggcta taaagcaggg ggtcctgacc gctggcggct tttcccctgc
6961 tgatgcagcc agaggtgctg tgaatgcgcc catgacacag gcgctggatt ggaacggcac
7021 aaggtattgg gcaccaggct ccatgaggac cacatcttac tctgggagat tcacatcaac
7081 cgctccagcg aggcaggccg acttccagca cacccaaagc cggccttcga gtggctcttc
7141 tgtgtcctcc tttgccactc agtcttcaag gccaactttg gccacaacca ctgggtcctc
7201 acatggcaca gcttcatcaa attcgactcg cagtactaac ctctcccagt caacagtttc
7261 tagagccaca tctagaactg gtgaatgggt tagagaccaa aatagaaatt tggaacccta
7321 tatgcatggt gccttacaga cagcctttgt caccccacct tccagtaggg cgtctgacgg
7381 gacagtctca accgtcccaa aaggtgtttt ggactcctgg acacctgcgt ttaacacccg
7441 caggcagccg ctttttgcac acctccgtaa gaggggggag tcacaagctt agtgaa
//