Typing tool
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Typing tool
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Complete norovirus genomes
| MK483909 | GII.4 Sydney | |
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| GII.P16 |
ORF1: 3..5102
ORF2: 5083..6705
ORF3: 6705..7511
LOCUS MK483909 7584 bp RNA linear VRL 23-APR-2019
DEFINITION Norovirus GII isolate
Hu/GII.P16-GII.4/RUS/Novosibirsk/NS18-A1494/2018, complete genome.
ACCESSION MK483909
VERSION MK483909.2
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7584)
AUTHORS Zhirakovskaya,E., Tikunov,A., Kravchuk,B. and Tikunova,N.
TITLE Molecular epidemiology of human norovirus associated with sporadic
gastroenteritis in Russia
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7584)
AUTHORS Zhirakovskaya,E., Tikunov,A., Kravchuk,B. and Tikunova,N.
TITLE Direct Submission
JOURNAL Submitted (04-FEB-2019) Siberian Branch of the Russian Academy of
Sciences, Institute of Chemical Biology and Fundamental Medicine
(ICBFM SB RAS), 8 Lavrentiev Avenue, Novosibirsk 630090, Russia
COMMENT On Apr 23, 2019 this sequence version replaced MK483909.1.
##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7584
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.P16-GII.4/RUS/Novosibirsk/NS18-
A1494/2018"
/isolation_source="diarrheal feces"
/host="Homo sapiens; sex: F; age: 15 Y"
/db_xref="taxon:122929"
/country="Russia: Novosibirsk"
/collection_date="03-Mar-2018"
/note="genotype: GII.P16/GII.4_variant _Sydney_2012"
gene 3..5102
/gene="ORF1"
CDS 3..5102
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBF80274.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARS
KQPAPRDEPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQ
PDVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
ISMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRMRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEV
EKAKRDFPGQPDMWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVK
TMEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQIDQNESEAKEE
VPKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPAGITEAFGVPIKQIQIHKSGEFCRFRFPRPIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLESAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSRISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 3..998
/gene="ORF1"
/product="p48"
mat_peptide 999..2096
/gene="ORF1"
/product="NTPase"
mat_peptide 2097..2627
/gene="ORF1"
/product="p22"
mat_peptide 2628..3026
/gene="ORF1"
/product="VPg"
mat_peptide 3027..3569
/gene="ORF1"
/product="Pro"
mat_peptide 3570..5099
/gene="ORF1"
/product="RNA-dependent RNA polymerase"
gene 5083..6705
/gene="ORF2"
CDS 5083..6705
/gene="ORF2"
/codon_start=1
/product="major capsid protein VP1"
/protein_id="QBF80275.2"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRVV"
gene 6705..7511
/gene="ORF3"
CDS 6705..7511
/gene="ORF3"
/codon_start=1
/product="minor capsid proteinVP2"
/protein_id="QCE20584.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARITTYNTGHFSTPQPSRALPERANLRGAVPARGPSNKPS
NSSTATSVYSNQTISTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
3'UTR 7512..7563
ORIGIN
1 gaatgaagat ggcgtctaac gacgctaccg ttgccgttgc ttgcaacaac aacaacgaca
61 aggaaaaatc ttcaggtgaa ggcttattca caaatatgtc ttccacctta aagaaagccc
121 tcggggctag gtccaaacag cctgccccga gagacgaacc acaaaagccc ccaagaccac
181 caactcccga gttggtcaag aggatacccc ctcccccacc taatggcgaa gaagaagaag
241 aaccagtcat taggtatgag gttaagagtg ggatctctgg cctgcccgag ctcacaacag
301 tcccccaacc ggacgtggcc aacacagcat tcagtgttcc accactgagc ttgagagaaa
361 acagggaggc caaggaaccg ctaacagggg caatactaga gatgtgggac ggagagatat
421 accactatgg cctgtacgtg gagaaaggct tagtgctggg tgtgcacaaa ccacctgcag
481 ccataagcat ggcaagagtg gagctaacgc cgctgtcatt gtactggcgt gtggtgtaca
541 ctccccaata cctcatctcc cctgaaactc tcaggaggct caacggagag gcgttccctt
601 acaccgcctt cgacaacaac tgctatgcct tttgctgctg ggtgttagac ctcaatgact
661 catggcttag caggaggatg gtgcaaagaa caacgggctt cttcagacct taccaagagt
721 ggaacagaaa acccctgccc accatggatg actccaaaat aaagaaggta gcaaatatat
781 tcctatgttc actgtccaca ttgttcacca gacctataaa agacctcata ggaaaaatta
841 aaccattaaa catattgaac atcctggcaa cgtgtgactg gacgtttgcc ggaatagtgg
901 agtctctgat attacttgct gaactcttcg gagttttctg gacaccccca gatgtgtctg
961 ctatgatcgc ccccttactc ggggactacg agttgcaagg gccagaagac ctcgccgttg
1021 aactcgtacc tgtggtaatg ggagggattg gtttggtgtt gggattcacc aaagagaaaa
1081 ttggcaaaat gttgtcctca gcagcatcaa cacttagggc ttgcaaagat cttggtgcct
1141 atggcttaga gatactcaaa ttggtcatga agtggttctt cccaaagaaa gaggaggcca
1201 atgagctagc catggtgagg gccatagagg atgccgtact agatcttgag gcaatagaaa
1261 ataaccacat gacaaccctg ttgaaagaca aagacagctt agcaacatac atgaaaacac
1321 tggacatgga ggaggagaaa gccagaaggt tgtccacaaa atctgcatcc cctgacatag
1381 ttgggacaat caacgccctg ctggctcgaa tagcagcagc caggtcatta gtccacaggg
1441 ccaaggaaga gctatctagc aggatgagac cagtggttgt tatgatatct ggtaaaccag
1501 gaataggcaa aactcatctg gccagggagg tggcaagaaa ggtagcatcc actctcacag
1561 gggatcaaag agtcggactc ataccaagaa acggtgtgga ccattgggat gcatacaaag
1621 gtgagagagt cgtgctgtgg gacgactatg gcatgagtaa ccccattcat gatgctcttc
1681 gcatacaaga attggctgat acgtgccccc ttaccttaaa ttgtgacaga attgaaaata
1741 agggaaaagt ttttgacagt gaagtcataa taattacaac aaaccttgcc aacccagccc
1801 cacttgatta tgtcaacttt gaggcctgtt ccaggagaat tgatttcctg gtgtacgctg
1861 aggcaccaga agtggaaaag gcaaaacggg attttcctgg ccagccagat atgtggaagg
1921 acgccttcaa gtcggacttt tcacacatca agctacagct tgcacctcaa ggcggctttg
1981 acaagaatgg caacacccca catgggaaag gggtgatgaa gaccctcact accggttctc
2041 tgattgcccg tgcatcgggc ctactacatg agaggatgga tgaatttgaa ctccaaggtc
2101 ccacaatcac caccttcaat ttcgaccgga acagaatcac agcattcaga caattggctg
2161 cagaaaacaa gtatgggttg gtggatacca tgaaagttgg caatcaacta aaaggagtga
2221 aaaccatgga agaactcaaa caagcaatca ggaatgtgac catcaagagg tgccggatca
2281 tctacggtgg ctctacgtat gaccttgaat ctgatggcaa gggcaaagtt ttggtggaaa
2341 aggtcaagaa cacctctgta cagaccaaca acgagttggc cggggccctg caccatctca
2401 aacacgcccg aatcaggtac tatgtcaaat gtgtgcaaga agcagtctat tccatcatac
2461 aaattgccgg cgctgcgttt gtcaccacgc gcattgcacg ccgcatgaac atacaagaac
2521 tctggtcgaa gccacaaata gatcaaaatg aatcagaagc taaggaagag gtccccaagt
2581 cagaagacga cgagttcatc atatcttcta aggacatcaa ggaggaagga aagaagggca
2641 aaaacaaaac tggccgtggc aagaaacaca ctgcattctc cagcaagggc ttgagcgatg
2701 aggagtatga cgagtacaag agaataagag aagagagaaa tgggaagtac tctatagagg
2761 agtatcttca agacagagac aggtactatg aggagctcgc cattgccaag gccacggaag
2821 aagacttctg tgaagaggag gagatcaaaa tccgccagag aattttccgt cccaccagga
2881 agcaaagaaa ggaagagagg gccacattag ggctggtaac aggttcagaa atcagaaaaa
2941 gaaatcctga tgacttcaaa cccaaaggga agctgtgggc cgatgacaac agaagtgttg
3001 actacaatga gaaactggac tttgaggccc ccccaagcat atggtctagg attgtgaact
3061 ttggttctgg ctggggcttc tgggtgtcac caagcctgtt cataacatca actcatgtaa
3121 tccccgcagg cataacagaa gcatttggag tccccatcaa acaaattcag atccacaaat
3181 caggtgaatt ttgccgattc agattcccaa gaccaattag accagatgtg acaggaatga
3241 tcttggaaga aggtgcgcct gaaggcaccg tggcaactgt gctcatcaaa cgccccaccg
3301 gagagctcat gcctcttgca gccagaatgg gaacacacgc aaccatgaaa attcaaggcc
3361 gcatggttgg cggacagatg ggcatgttgc tcactggatc gaatgctaaa ggaatggatt
3421 tgggaacaac tcctggtgac tgtggctgtc cttacatcta taaaaggggc aatgactata
3481 tagtcatcgg ggtgcacact gcagcagccc gtggtggaaa caccgtcatc tgtgccacac
3541 agggaagtga gggtgaggca actcttgagg gtggagatga taaaggaaca tactgtgggg
3601 cacccatttt gggccctggg ggtgcaccaa aattgagcac caaaaccaaa ttttggaggt
3661 catcgaacac gccccttcca ccagggacat atgagcctgc ctacctcggt ggccgtgatc
3721 cgcgtgttaa gggtgggccc tccttgcagc aggtaatgag agaccagttg aagccattca
3781 ctgaacccag gggcaaacct ccaagaccaa gtgtattgga atcagccaaa caaaccatta
3841 tcaatgttct cgaacaaacc ctggaccctc cacaaaaatg gacatatgca caggcgtgtg
3901 cctcacttga caaaaccacc tccagcgggc atccccatca cgtccgaaag aatgaattct
3961 ggaatggtga gaccttcact ggtaaattgg cagaccaagc atcaaaagca aacctaatgt
4021 ttgaggaagg gaaacacatg acaccagtgt acacagcagc actcaaggac gagctagtta
4081 agactgagaa aatctatgga aagatcaaga agagactgct ctggggctct gacttgtcca
4141 ccatgatccg gtgcgctagg tcatttggtg ggctcatgga cgagatgaag gcacactgca
4201 tatcactccc agtacgagtt ggcatgaata tgaatgaaga tggcccaata atatttgaga
4261 aacattccag atataaatac cattatgatg cagactactc tcgttgggat tcaacacaac
4321 agagggcagt actagcagca gccttggaaa tcatggtcag attctctgca gaaccacaat
4381 tggcacaaat agtcgctgag gatctactgg cccctagtgt agtagatgta ggagacttta
4441 aaatcacaat aaatgagggg ctcccatctg gtgtgccatg tacttctcaa tggaactcca
4501 tcgcacactg gctgctaact ctctgtgcct tgtctgaagt cactaaattg tcccctgaca
4561 ttatacaagc aaattccatg ttctcatttt acggtgatga cgagattgtc agcaccgaca
4621 taaaattgga ccctgaacag ttaaccgcca agttgaagga gtacggcctg aaaccaaccc
4681 gcccagacaa gaccgaggga cccctgatca tcagtgaaga tttgaacgga ctcactttcc
4741 tacgaaggac ggtgactcgt gacccagctg gctggtttgg aaaactggac caaagttcaa
4801 ttttgaggca gatgtactgg actagaggac caaatcatga agatcccaat gagacaatga
4861 taccccattc tcaaagaccc atacagctca tggcactgct tggtgaagcc tctcttcacg
4921 gaccctcttt ctacagtaga atcagtaaat tggttataac tgaactcaaa gaaggtggga
4981 tggactttta cgtgccaagg caggaaccca tgttcaggtg gatgaggttt tctgacttga
5041 gcacgtggga gggcgatcgc aatctggctc ccaattttgt gaatgaagat ggcgtcgagt
5101 gacgccaacc catctgatgg gtccgcagcc aacctcgtac cagaggtcaa caatgaggtt
5161 atggctttgg agcccgttgt tggtgccgct atcgcggcac ctgtagcggg ccaacaaaat
5221 gtaattgacc cctggattag aaataatttt gtacaagccc ctggtgggga gtttacagtg
5281 tcccctagaa acgctccagg tgaaatacta tggagcgcgc ccctaggccc tgatttaaat
5341 ccctacctat cccatttggc cagaatgtat aatggttatg caggtggttt tgaagtgcag
5401 gtaattctcg cggggaacgc gttcaccgcc gggaagatta tatttgcagc agtcccacca
5461 aatttcccaa ctgaaggctt aagtcctagc caggtcacta tgttccccca tataatagta
5521 gatgttagac aactagaacc tgtgctgatt cccttacccg atgttaggaa taatttctat
5581 cattacaatc agtcaaatga ctccactatt aagttgatag caatgttgta tacaccactt
5641 agggctaata atgctggaga tgatgttttc acagtttcgt gccgagttct cacgagacca
5701 tcccccgatt ttgatttcat atttttagtg ccacccacag ttgagtcaag aactaaacca
5761 ttctctgtcc caattttaac tgttgaggag atgactaatt caagattccc catccctttg
5821 gaaaagttgt tcacaggccc cagcagtgcc tttgttgttc aaccacaaaa cggcaggtgt
5881 acaactgatg gcgtgctcct aggcaccacc caactctctc ctgtcaacat ctgcaccttc
5941 agaggggatg tcacccacat cacaggtagt cgcaactaca caatgaattt ggcttctcaa
6001 aattggaaca actatgaccc aacagaagaa atcccagccc ctctaggaac tccagatttt
6061 gtggggaaga ttcaaggcat gctcacccaa accacaagga cagatggttc aacacgcggc
6121 cacaaagcta cagtgtacac tggaagtgcc gactttgctc caaaactggg tagagttcaa
6181 tttgaaactg acacagacca tgattttgaa gctaatcaaa atacaaagtt caccccagtc
6241 ggtgtcatcc aagatggtag caccacccac cgaaacgaac cccaacagtg ggtgctccca
6301 agttactcag gcagaaacac tcacaatgta catttggccc ccgctgtagc ccccaccttt
6361 ccgggtgagc aacttctctt cttcagatcc accatgcccg gatgcagcgg gtaccccaac
6421 atggatttgg actgtctgct cccccaggaa tgggtgcagt acttctacca agaggcagcc
6481 ccagcacaat ctgatgtggc tttgctaaga tttgtgaatc cagacacagg tagggttttg
6541 tttgagtgca agcttcataa atcaggctat gttacagtgg ctcacactgg ccaacatgat
6601 ttggttatac cccccaacgg ttactttagg tttgattcct gggtcaacca gttctacaca
6661 cttgccccca tgggaaatgg aacggggcgt agacgtgtag tataatggct ggagctttct
6721 ttgctggatt ggcatctgat gtccttggct ctggacttgg ttcccttatc aatgctgggg
6781 ctggggccat caaccaaaaa gttgaatttg aaaataacag aaaattgcaa caagcatcct
6841 tccaatttag cagtaatctg caacaggctt ccttccaaca tgataaagag atgctccaag
6901 cacaaattga ggccaccaaa aagctacaac aggaaatgat gaaagttaag caggcaatgc
6961 tcctagaggg tgggttctct gagacagatg cagcccgcgg ggcaattaac gcccccatga
7021 caaaagcttt ggactggagc gggacaaggt attgggctcc agatgctagg attacaacat
7081 acaatacagg ccacttttcc acccctcaac catcgagggc actgccagaa agagctaatc
7141 ttaggggtgc tgtccctgct cgaggaccct ccaacaaacc ctctaactct tctactgcca
7201 cctctgtgta ctcaaatcaa actatttcaa cgagacttgg ttctacagct ggttctggaa
7261 ccagtgtctc gagcctcccg tcaactgcaa ggactaggag ctgggttgag gatcaaaata
7321 ggaatttgtc acctttcatg aggggggccc acaacatatc atttgtcacc ccaccatcta
7381 gcagatcctc tagccaaggc acagtctcaa ccgtgcctaa agagattttg gactcctgga
7441 ctggcgcttt caacacgcgc aggcagcctc tcttcgctca cattcgtaag cgaggggagt
7501 cacgggtgta atgtgaaaag acaaaactga ttatttttct ttttcttttc tttagtgtct
7561 tttaaaaaaa aaaaaaaaaa aaaa
//