Typing tool
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Typing tool
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Complete norovirus genomes
| MK355712 | GII.12 | |
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| GII.P16 |
ORF1: 1..5094
ORF2: 5075..6682
ORF3: 6682..7406
LOCUS MK355712 7406 bp RNA linear VRL 31-JUL-2019
DEFINITION Norovirus GII isolate HU/GII.P16_GII.12/AlbertaEI464/CA/2018
nonstructural polyprotein (ORF1) gene, partial cds; VP1 (ORF2)
gene, complete cds; and VP2 (ORF3) gene, partial cds.
ACCESSION MK355712
VERSION MK355712.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7406)
AUTHORS Pabbaraju,K., Wong,A.A., Tipples,G.A. and Pang,X.L.
TITLE Emergence of a Novel Recombinant Norovirus GII.P16-GII.12 Strain
Causing Gastroenteritis, Alberta, Canada
JOURNAL Emerging Infect. Dis. 25 (8), 1556-1559 (2019)
PUBMED 31310222
REFERENCE 2 (bases 1 to 7406)
AUTHORS Pang,X.L., Pabbaraju,K., Wong,A.A. and Tipples,G.A.
TITLE Direct Submission
JOURNAL Submitted (02-JAN-2019) Molecular Diagnostics, Provincial
Laboratory For Public Health, 3030 Hospital Dr. NW, Calgary, AB T2N
4W4, Canada
FEATURES Location/Qualifiers
source 1..7406
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="HU/GII.P16_GII.12/AlbertaEI464/CA/2018"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Canada:Alberta"
/collection_date="Oct-2018"
/note="genotype: GII.P16_GII.12"
gene <1..5094
/gene="ORF1"
CDS <1..5094
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QAT98447.1"
/translation="MASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARPKQ
PAPRDKPQNPPRPLTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQPD
VANTAFSVPPLSLRESREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAIS
MAKVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIGK
IKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRMRPVVVMISGKPGIGKTHLAREV
ARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADTC
PLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPDVEK
AKRDFPGQPDMWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVKTM
EELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVKNASVQTNNELAGALHHLK
HARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEEAP
KPEDDEFVISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKY
SIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTG
SEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSL
FITSTHVIPTGITEAFGVPIKQVQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEGTV
ATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCG
CPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPG
GAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRG
KPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPYHVRKNEFWNG
ETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGRIKKRLLWGSDLST
MIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYQYHYDADYSRWDST
QQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCTSQ
WNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTTKLKEY
GLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNH
EDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEPM
FRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide <1..990
/gene="ORF1"
/product="p48"
mat_peptide 991..2088
/gene="ORF1"
/product="NTPase"
mat_peptide 2089..2619
/gene="ORF1"
/product="p22"
mat_peptide 2620..3018
/gene="ORF1"
/product="VPg"
mat_peptide 3019..3561
/gene="ORF1"
/product="Pro"
mat_peptide 3562..5091
/gene="ORF1"
/product="RdRp"
gene 5075..6682
/gene="ORF2"
CDS 5075..6682
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QAT98448.1"
/translation="MKMASNDAAPSNDGAAGLVPEVNNETMALEPVAGASIAAPLTGQ
NNVIDPWIRLNFVQAPNGEFTVSPRNSPGEVLLNLELGPELNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKLVFAAVPPHFPLENISPGQITMFPHVIIDVRTLEPVLLPLPD
VRNSFFHYNQQNEPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFNYLVPP
TVESKTKPFTLPVLTIGELTNSRFPVPIDELYTSPNESLVVQPQNGRCALDGELQGTT
QLLPTAICSFRGRINQKVSGENHVWNMQVTNINGTPFDPTEDVPAPLGTPDFSGKLFG
VLSQRDHDNACRSHDAVIATDSTKFTPKLGAVQIGTWEQDDVHINQPTKFTPVGLFEN
EGFNQWTLPNYSGALTLNMGLAPPVAPTFPGEQILFFRSHIPLKGGVADPVIDCLLPQ
EWIQHLYQESAPSQTDVALIRFTNPDTGRVLFEAKLHRSGYITVANTGSRPIVVPANG
YFRFDSWVNQFYSLAPMGTGNGRRRMQ"
gene 6682..>7406
/gene="ORF3"
CDS 6682..>7406
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QAT98449.1"
/translation="MAGAFIAGLAGDIVTNSIGSLVNAGANAINQKVDFENNKQLQQA
SFNHDKEMLQAQIQATKQLQADMITIRQGVLTAGGFSPTDAARGAVNAPMTQVLDWNG
TRHWAPGATKTTAFSGGFTSASHARTVDLTKKTSATPAPMPVSRPSSIASTVSTRSTL
ISGSSNPPSSVRSSSSVSSQPTSSSSRISEWVRSQNRALEPYMNGALRTAYVTPPSSR
ASSNGTVSTVPKEVLDSWTPAFNT"
ORIGIN
1 atggcgtcta acgacgctac cgttgccgtt gcttgcaaca acaacaacga caaggaaaaa
61 tcttcaggtg aaggcttatt cacaaatatg tcttccacct taaagaaagc cctcggggct
121 aggcccaaac agcctgcccc gagagacaaa ccacaaaatc ccccaagacc actaactccc
181 gagttggtca agaggatacc ccctcctcca cctaatggcg aagaagaaga agaaccagtc
241 attaggtatg aggttaagag tgggatctct ggcctgcccg agctcacaac agtccctcaa
301 ccggacgtgg ccaacacagc attcagtgtt ccaccactga gcttgagaga aagcagggaa
361 gccaaggaac cgctgacagg ggcaatatta gagatgtggg atggagagat ataccactac
421 ggcctgtacg tggagaaagg cttagtgttg ggtgtacaca aaccacctgc agccataagc
481 atggcaaaag tggagctgac gccgctgtca ttgtattggc gtgtggtgta cactccccaa
541 tacctcatct ctcctgaaac tctcaggagg ctcaacggag aggcattccc ttacaccgcc
601 tttgacaaca actgctatgc cttttgctgc tgggtattag acctcaatga ctcatggctt
661 agcaggagaa tggtgcaaag aacaacgggc ttcttcagac cttaccaaga gtggaacaga
721 aaacccctgc ctaccatgga cgactccaaa attaagaagg tagcaaatat attcctatgt
781 tcattgtcca cattgttcac tagacccata aaagacctca taggaaaaat taaaccatta
841 aacatattga atatcctggc aacgtgtgac tggacgtttg ccggaatagt ggagtctcta
901 atactacttg ctgaactctt cggagttttc tggacacccc cagatgtgtc tgctatgatc
961 gctcccttac ttggggatta cgagttgcaa gggccagaag acctcgccgt tgaactcgta
1021 cctgtggtga tgggtgggat tggtttggtg ttgggattca ccaaagagaa aattggcaaa
1081 atgttgtcct cggcagcatc aacactcagg gcttgcaaag accttggtgc ctatggctta
1141 gagatactca aattggtcat gaagtggttc ttcccaaaga aagaggaggc caatgagcta
1201 gccatggtga gggccataga ggacgctgta ctagatcttg aggcgataga aaataaccac
1261 atgacaaccc tgttgaaaga caaagacagc ttagcaacat acatgaaaac actggacatg
1321 gaggaggaga aagccagaag gttgtccaca aaatctgcat cccctgacat agttgggaca
1381 atcaacgccc tgctggctcg aatagcagcg gccaggtcat tggtccacag ggccaaggaa
1441 gagctatcta gcaggatgag accagtagtt gttatgatat ctggcaaacc aggaataggc
1501 aaaactcatc tggccagaga agtggcaaga aaggtggcat ccactctcac aggggatcaa
1561 agagtcgggc tcataccaag aaacggtgtg gaccattggg atgcatacaa aggtgagaga
1621 gtcgtgctgt gggacgacta tggcatgagt aaccccattc atgatgctct tcgcatacaa
1681 gaattggctg atacgtgtcc cctcacctta aattgtgaca gaattgaaaa taaaggaaaa
1741 gtttttgaca gtgaagtcat aataatcaca acaaaccttg ccaatccagc cccgcttgat
1801 tatgtcaact ttgaggcctg ttccaggaga attgatttcc tggtgtacgc tgaggcacca
1861 gatgtggaaa aggcaaaacg ggactttcct ggtcagccag atatgtggaa ggacgccttc
1921 aaatcggact tttcacacat caagctacag cttgcacctc agggcggctt tgacaaaaac
1981 ggcaacaccc cacatgggaa aggggtgatg aagaccctca ctaccggttc cctgattgcc
2041 cgtgcatcag gcctactgca tgagaggatg gatgaatttg aactccaagg tcctacaatc
2101 accaccttca atttcgaccg gaacagaatc acagcattca gacaattggc tgcagaaaac
2161 aagtatggac tggtggacac catgaaagtc ggcaatcaat taaaaggagt gaaaaccatg
2221 gaagagctca aacaagcaat caggaatgtg accatcaaga ggtgccggat catctacggt
2281 ggctccacat atgaccttga atctgatggt aagggcaaag ttttggtgga aaaggtcaag
2341 aacgcctctg tacagaccaa caacgagttg gccggggccc tgcaccatct caaacacgcc
2401 cgaatcaggt actatgtcaa gtgtgtgcaa gaagcagtct attctatcat acaaattgcc
2461 ggcgctgcgt ttgtcaccac gcgcattgca cgccgcatga acatacaaga actctggtcg
2521 aagccacaat tggatcaaaa tgaatcagag actaaggaag aggcccccaa gccagaagat
2581 gacgagttcg tcatatcttc taaggacatc aaggaggaag gaaagaaggg caagaataaa
2641 actggccgtg gcaagaaaca cactgcattc tccagcaagg gcttgagcga tgaggagtat
2701 gacgagtaca agaggataag agaagagaga aatgggaagt actctataga ggaatatctt
2761 caagacagag acaggtacta tgaagaactc gccattgcca aggccacgga agaagacttc
2821 tgtgaagagg aggagataaa aatccgtcag agaattttcc gtcctaccag gaaacaaagg
2881 aaggaagaga gggccacatt agggctagta acaggttcag aaatcagaaa aaggaatcct
2941 gatgacttca aacccaaagg gaagctgtgg gccgatgaca acagaagtgt tgactacaat
3001 gagaaactgg attttgaggc ccccccaagc atatggtcta ggattgtgag ctttggttct
3061 ggctggggct tctgggtatc accaagcctg ttcataacat caactcatgt aatccccaca
3121 ggcataacag aagcatttgg agtccccatc aaacaagttc aaatccacaa atcaggtgaa
3181 ttttgccgat tcagattccc aaagccaatt agaccagatg tgacaggaat gatcttggaa
3241 gaaggtgcgc ctgagggcac cgtggcaact gtgctcatca aacgccccac cggagagctc
3301 atgcctcttg cagccagaat gggaacacac gcaaccatga aaattcaagg ccgcatggtt
3361 ggcggacaga tgggcatgtt gctcactggg tcaaatgcta aaggaatgga tttgggaaca
3421 actcctggag actgtggctg tccttacatc tataaaaggg gcaatgacta catagtcatt
3481 ggggtgcaca ctgcagcagc ccgtggtgga aacaccgtca tctgtgccac acagggaagt
3541 gagggtgagg caactcttga gggtggagat gacaagggaa catattgtgg ggcacccatc
3601 ctaggccctg ggggtgcacc aaaattgagc accaaaacca aattttggag gtcatcgaac
3661 acgccccttc caccagggac atatgagcct gcctacctcg gcggccgtga cccgcgtgtt
3721 aagggtgggc cctccttgca gcaggtaatg agagaccagt tgaagccatt cactgaaccc
3781 aggggcaaac ctccaagacc aagtgtattg gaagcagcca aacaaaccat catcaatgtc
3841 ctcgagcaaa ccctggaccc tccacaaaaa tggacatacg cacaggcgtg tgcctcgctt
3901 gacaaaacaa cctctagcgg tcacccctat cacgttcgaa agaatgaatt ctggaatggt
3961 gagaccttca ctggtaaatt ggcagaccaa gcatcaaaag caaacctaat gtttgaggaa
4021 gggaaacaca tgacaccagt gtatacagca gcactcaagg acgagctagt caagactgag
4081 aaaatctatg gaaggatcaa gaagagactg ctctggggct ctgatttgtc caccatgatc
4141 cggtgcgcta ggtcgtttgg tgggctcatg gacgagatga aggcacactg catatcactc
4201 ccagtccgag ttggcatgaa tatgaatgaa gatggcccaa taatatttga gaaacattct
4261 agataccaat atcactatga tgcagactac tctcgttggg attcaacaca acagagggca
4321 gtactggcag cagccttgga aatcatggtc agattctctg cagaaccaca attggcacaa
4381 atagtcgctg aggacctact ggcccctagt gtagtagatg taggagactt taaaatcaca
4441 ataaatgagg ggctcccctc tggtgtgcca tgcacttctc aatggaactc catcgcacac
4501 tggttgctaa ctctctgtgc cttgtctgaa gtcactaagc tgtcacctga cattatacag
4561 gcaaattcca tgttctcatt ttacggtgat gacgagattg tcagcaccga cataaagttg
4621 gaccccgaac agttaaccac caaattgaag gagtacggcc taaaaccaac ccgcccagat
4681 aaaaccgagg gacccctgat catcagtgaa gatttgaacg gactcacttt cctccgaagg
4741 acggtgactc gtgacccagc tggctggttt ggaaaactgg accaaagctc aattttgagg
4801 cagatgtact ggactagagg accaaatcat gaagacccca atgagacaat gataccccat
4861 tctcaaaggc ccatacagct catggcactg cttggtgaag cctctcttca cggaccctct
4921 ttctacagta aaatcagcaa attggtcata actgaactca aagaaggtgg gatggacttt
4981 tacgtgccaa ggcaggaacc catgttcagg tggatgaggt tttctgactt gagcacgtgg
5041 gagggcgatc gcaatctggc tcccaatttt gtgaatgaag atggcgtcga atgacgccgc
5101 tccatctaat gatggtgcag ccggtctcgt accagaggtc aacaatgaga ccatggcact
5161 tgaaccggtg gctggggctt cgatagccgc cccactcacc ggccaaaata atgttataga
5221 cccctggatt agattaaatt ttgtgcaggc ccctaatgga gagtttacag tctcaccccg
5281 caactcgcct ggggaagtcc tactcaattt ggaattaggc cccgaattga atccatattt
5341 ggcacacctt tctagaatgt ataatggtta tgcaggtgga gttgaggtgc aagtgctact
5401 ggctgggaac gcgttcacgg ctggaaaatt ggtatttgct gcagttcccc ctcattttcc
5461 attagagaat ataagccctg gccaaataac catgttccct catgtaatta ttgatgttag
5521 gactttggaa ccagtcttat tgcctctacc agatgtcaga aatagcttct tccattacaa
5581 tcagcaaaat gagccgagga tgaggcttgt tgcaatgctt tatacccctc ttagatctaa
5641 tggttctggt gatgatgtgt tcaccgtctc ctgtagggtg ctcactcgac cctctcctga
5701 ttttgatttt aattatttgg tgcccccaac agttgaatct aaaacaaaac cattcacact
5761 ccctgtcttg accattgggg agttaaccaa ttccaggttc cctgtgccta tagatgaact
5821 ctacactagc cccaatgaga gtttggtggt tcaaccccag aatgggaggt gcgcgctgga
5881 tggggagttg cagggcacca cccagctcct tcccacggcg atttgctcgt tcaggggtcg
5941 gatcaatcag aaagtgagtg gagagaatca tgtttggaac atgcaagtca ccaacattaa
6001 cggaacccct tttgacccaa cagaggatgt tccagcccct ctgggcacgc cagacttttc
6061 tggcaagctc tttggtgtcc taagccagag ggaccatgat aatgcctgca ggagtcatga
6121 tgcagtgatt gcaactgatt ctaccaaatt taccccaaaa ttgggtgctg tacaaattgg
6181 cacatgggaa caagatgatg tacacatcaa ccaacccacc aagtttactc cagttggatt
6241 gtttgagaat gaaggtttta atcaatggac acttcctaat tattctggag ctttaacact
6301 caatatgggg ttggcccccc ctgtggcccc cacattccct ggtgagcaaa ttctcttctt
6361 caggtcccac attcccctta aaggaggtgt tgcagaccca gttattgatt gtcttctacc
6421 ccaagagtgg atccaacacc tttatcagga gtcagcccct tcacaaacag atgtggcact
6481 gattagattc acaaatccag acacagggcg tgtcctattt gaagcaaaat tacacaggag
6541 tggttacatc acagtggcca acactggtag cagaccaatt gtggtgccag ctaatggtta
6601 tttcaggttt gactcttggg ttaatcagtt ttactctctt gcccccatgg gaactgggaa
6661 tgggcgcaga aggatgcagt aatggctgga gctttcatag cagggcttgc cggtgacata
6721 gtcaccaaca gcattggctc actcgtgaac gctggggcca atgcaataaa ccagaaagta
6781 gactttgaaa acaacaagca actacaacag gcatctttca accatgacaa agagatgttg
6841 caagctcaaa ttcaggccac caaacagcta caggctgata tgattacaat cagacaaggg
6901 gtgttgaccg caggcggctt ctcccctact gatgcagcaa gaggtgcagt caacgcgccc
6961 atgactcaag tcttggattg gaatgggacc agacattggg cccccggagc cacgaaaaca
7021 actgctttct ccggtgggtt taccagtgcc tctcatgcca ggaccgttga cctgaccaag
7081 aagacatcag ccacaccagc ccctatgcct gtttctaggc ccagttctat tgcttccact
7141 gtttctactc gctctacttt gattagtggg tcctctaatc ctccttcttc agttaggagc
7201 tcttctagtg tttcttccca acccacttcc tcgtcctccc gaattagtga gtgggtacgt
7261 agtcaaaata gggcgctgga gccttatatg aatggggcgc tgcgtacagc ctacgtgacg
7321 cctccatcca gtagggcttc tagcaatggc acagtctcaa ccgtgccaaa agaggttttg
7381 gactcctgga cacctgcgtt taacac
//