Typing tool
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Typing tool
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Complete norovirus genomes
| MK301293 | GII.6 | |
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| GII.P7 |
ORF1: 1..5088
ORF2: 5069..6712
ORF3: 6712..7491
LOCUS MK301293 7534 bp RNA linear VRL 05-APR-2019
DEFINITION Norovirus GII isolate Hu/GII.P7-GII.6/Maryland/USA/2018
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK301293
VERSION MK301293.1
DBLINK BioProject: PRJNA490509
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7534)
AUTHORS Yang,Z. and Mammel,M.
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2018) OARSA, CFSAN, FDA, 8301 Muirkirk Rd.,
Laurel, MD 20708, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.1
Assembly Name :: E59S7r_trimmed_contig_129-RC
Coverage :: 195
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7534
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.P7-GII.6/Maryland/USA/2018"
/isolation_source="feces"
/host="Homo sapiens; female"
/db_xref="taxon:122929"
/country="USA"
/collection_date="18-Apr-2018"
/note="genotype: GII.P7-GII.6"
gene <1..5088
/gene="ORF1"
CDS <1..5088
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QBB90025.1"
/translation="MASNDATTAFGSQNSVNDSTNTAPSDKEEVGALSNIKVGFKKIL
GAVPKGTKAPSSGQHCPTVKIGAKTLTVPPEPPNGEDTVQFDAKSETVRGLPDLTTVQ
NEHENTPYTVPPLSEREHRPATEPLPGTILEMWDGEFYHYSVYVSGGKALGVHKPPAA
ISLATIELTPISLYWRPVYTPNYLVCPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELN
DTWLSRRCISRTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLL
GKLKPLNLLHLLASCDWTFAGVVETVILMAELFNIFWTPPDVSNFIASLIGDFELQGP
EDLAVELVPVVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWF
FPKKEEKAEMETLRAIEDAVLDMEAIGNNHLTTLLKDKDSLAAFMKTLDLEEEKARKL
STKSSSPDIVGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMAR
HLAKTIANTMSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQELAD
TCPVTLNCDRIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEI
EKVKKDFPGQPDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTA
RVAGLVHERRDEFQLQGNDLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGAALKSVK
TLEDLKIALRDVKFNECEIIYRNSRYRVSSNGKGSVSVDKVEDQTSQTANEVGAAILR
LRQARARYYVSCFQDLVYTLMQVAGASFVVSRISKRFCWEKWVKPTETQETIESEKEV
AQGKWEIEPKDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSI
EEYLQDRDRYYEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTGSD
IRKRRPDDFQPKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLI
TTTHVLPKGLKELFGVEIKQIQIHKSGEFCRFRFPRPIRQDVTGLVLEEGAPEGTVCS
ILVKRPTGEMIPLAVRMGTHATMRIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCP
YIYKRGNDIVVAGVHTAAARGGNTVICATQGQDGEAVLEGNENLGTYCGAPILGPGKA
PKLSTKTKFWRSSPDVLPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRGKP
PRPAVLEEAKKTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHVKKNDHWNGES
FTGPLADQASKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMI
RCARAFGGLMDSMKASCITLPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQ
RSVLAAAMEVMVRFSAEPDLAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWN
SIAHWILTLSAMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGL
VPTRPDKTEGSLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHEN
PYESMVPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFR
WMRFSDLSTWEGDRNLAPEGVNEDGVE"
mat_peptide <1..996
/gene="ORF1"
/product="p48"
mat_peptide 997..2094
/gene="ORF1"
/product="NTPase"
mat_peptide 2095..2613
/gene="ORF1"
/product="p22"
mat_peptide 2614..3012
/gene="ORF1"
/product="VPg"
mat_peptide 3013..3555
/gene="ORF1"
/product="Pro"
mat_peptide 3556..5085
/gene="ORF1"
/product="RdRp"
gene 5069..6712
/gene="ORF2"
CDS 5069..6712
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBB90027.1"
/translation="MKMASNDAAPSNDGAANLVPEANNEVMALEPVVGASIAAPVVGQ
QNIIDPWIRENFVQAPQGEFTVSPRNSPGEMLLNLELGPELNPYLSHLSRMYNGYAGG
MQVQVVLAGNAFTAGKIIFAAVPPHFPVENISAAQITMCPHVIVDVRQLEPVLLPLPD
IRNRFFHYNQENTPRMRLVAMLYTPLRANSGEDVFTVSCRVLTRPAPDFEFTFLVPPT
VESKTKPFTLPILTLGELSNSRFPAPIDMLYTDPNEGIVVQPQNGRCTLDGTLQGTTQ
LVPTQICAFRGTLISQTSRSSDSTDSAPRRRDHPLHVQLKNLDGTQYDPTDEVPAALG
AIDFKGTVFGVASQRDVSGQQVGATRAHEVHVNTTDPRYAPKLGTILMHSESDDFVTG
QPICFTPIGMGDNDWHQWELPDYSGHLTLNMNLAPAVAPAFPGERILFFRSVVPSAGG
YGSGQIDCLIPQEWVQHFYQEAAPSQSAVALIRYVNPDTGRNIFEAKLHREGFITVAN
SGNNPIVVPPNGYFRFEAWVNQFYTLTPMGTGQGRRRNQ"
gene 6712..7491
/gene="ORF3"
CDS 6712..7491
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBB90026.1"
/translation="MASAFLAGLAGDAITNGVGSLINAGANAINQKVEYDFNKQLQMA
SFKHDKEMLQSQVLATKQLQQEMMNIRQGVLTAGGFSPADAARGAVNAPMTKILDWSG
TRYWAPNSMKTTSYSGQFSSSPVHKSPAPSQHAVPSKSRLQSDSVSVYSSPSSVSSQS
TQSTVLSSGTRSSRSISTSTATPTLSRTSDWVRGQNERLSPFMDGALQTAFVTPPSSK
ASSNGTVSTVPKAVLDSWTPMFNTHRQPLFAHLRRRGESQI"
ORIGIN
1 atggcgtcta acgacgctac cactgccttt ggcagccaaa actctgtcaa tgacagtacc
61 aacaccgccc cttctgacaa agaagaggtt ggtgcactct ccaacatcaa agttggtttt
121 aagaaaatac tgggtgccgt tcccaagggg accaaagcac ccagtagtgg tcagcactgc
181 cccacggtca agatcggggc caaaacatta acggtccccc ctgagccccc aaatggtgaa
241 gataccgtgc agtttgacgc gaagtcggaa actgtgcgtg ggttgccaga cttgacaacg
301 gtgcagaacg aacacgaaaa cacaccatac actgttcccc cattgagtga aagagagcac
361 agaccagcca ctgaaccgct tcctggcaca atactggaga tgtgggacgg tgaattctac
421 cattactctg tgtacgtcag cggtggcaaa gccttggggg ttcataagcc ccctgcagcg
481 ataagcctcg cgacgataga gctcacaccc atatctcttt attggaggcc cgtttacacc
541 cccaactatc tggtctgtcc agacacgttg aagggccttg ctggtgaaaa gttcccctac
601 acggccttca gcaacaactg ttacaacttc tgttgctggg tgcttgagct caatgacaca
661 tggctcagca ggaggtgcat ctccaggacc accggcttct tcaagccgta tcagtcttgg
721 aataggaaac cccttcctac cgttgatgat ggaaagatca aaaaggtagc caacgcaatt
781 ctttgcgcac ttggatcact gttttcaaaa ccaattaagg acttattggg caaacttaaa
841 ccattgaact tgctgcacct gctcgcatca tgtgactgga cgtttgcggg tgtagtagag
901 acagttatcc taatggcgga acttttcaac atcttttgga caccgccaga tgtttccaac
961 ttcatagcct ccctgatagg tgactttgaa ttgcaagggc ctgaggacct ggctgtggag
1021 cttgtccccg tggtcatggg tggcatagga atggttctcg gctttactgc tgagaagata
1081 ggccgcatgc tgtcgtccgc tgcatcaaca ctgcgggcat gcaaagactt ggggaattat
1141 gcccttgaca ttttaaaact ggttatgaag tggttcttcc caaagaaaga agagaaagcc
1201 gagatggaaa ccctgagggc gattgaggat gccgtcctgg acatggaagc tataggaaac
1261 aaccatctta caacccttct caaggacaag gatagcctcg cagcttttat gaagactctg
1321 gacctagaag aggagaaggc aaggaagctg tccactaagt catcctcgcc agacatcgtc
1381 ggcactatca atgccatact ggccagaata gctgctgcca ggtccctcct acacaaggcc
1441 aaagaagaaa tgttcagtag gatcagaccc gtggttgtta tgatctcggg tagacctggc
1501 atcggcaaga cccacatggc aaggcacttg gccaagacta tcgccaacac catgagcggc
1561 gaccagagag tagggctcgt cccacgcaat ggagtcgatc actgggacgc ttacagggga
1621 gaaagggtgg tcttatggga tgattacggc atgggaaacc ctgtcaaaga tgccctaaca
1681 ttgcaagagc tggctgacac ctgcccagta actctaaact gtgacaggat tgagaacaag
1741 gggaagatgt tcgacagtga tgtcatcata atcacgacca acttggttaa cccggcgccc
1801 ctcgattatg tgaacttcga ggcgtgctcc agaagagttg actttctggt ctatgcagag
1861 tcaccagaaa ttgagaaggt taagaaagat ttccccggcc aacctgacat gtggaaggac
1921 cattttaagc cagacttttc ccacataaaa ctgactctag ccccacaggg tggatttgat
1981 aagaacggca atactccgca tggtaagggc accatgcgat ccctaaccca ggggtccctg
2041 actgcaaggg ttgcaggcct tgttcatgag aggagagacg agttccaact ccaagggaac
2101 gaccttcaaa catacaactt tgataccaac agggtctctg cgtttaggaa gctagccgca
2161 gacaacaagt atgggatcat ggagacaatg agagtgggcg cggcgttgaa gagcgtcaag
2221 accttggaag atctgaaaat tgccctgagg gatgtgaagt tcaatgagtg tgagataatc
2281 tacagaaact ccagataccg agtctcttcc aatggcaaag gttctgtctc tgtcgacaaa
2341 gttgaggacc agacatccca gactgcaaac gaagtgggtg cagcaatcct tagactcagg
2401 caggcaagag ccagatacta tgtcagctgc ttccaagacc tcgtctacac tctaatgcag
2461 gtcgccggag catcattcgt tgtcagtagg atctctaaga ggttctgctg ggagaaatgg
2521 gtcaaaccaa ccgagaccca ggaaacgatt gaatccgaaa aggaagtagc ccaaggcaaa
2581 tgggagattg aacccaagga tacagaacca gaaggtaaga agggtaagaa caagaaagga
2641 agaggcaaga aacacacagc cttctctagc aaaggcctta gtgatgagga gtatgatgag
2701 ttcaagagga tcagggaaga aaggaacgga aaatactcca ttgaggaata cctgcaagac
2761 cgggaccgct actatgagga agtggcagtt gcccgggcaa cagaggagga cttctgtgaa
2821 gaggaggagg ccaagataag acaaagaatc tttcgcccca caaagaaaca aaggaaggaa
2881 gaaaggggag tgcttggcct ggtcactggc tcagacatca ggaagaggag accagacgat
2941 ttccaaccga agggcaatct gtgggcagac gacaccagga gtgtggacta caacgagaga
3001 cttgatttcg aggccccccc gagtgtctgg tcaagaatag tcccattggg cactggctgg
3061 ggcttctggg tctcatccaa cctcctgatc acaacaacac acgtcctacc taaggggctc
3121 aaggaacttt ttggagttga aatcaaacag atccaaattc acaaatctgg agagttctgc
3181 aggttcagat tcccgagacc gatcagacaa gatgtcacag ggctcgtgtt ggaggaaggt
3241 gccccagaag gcactgtctg ctccatactc gtgaagagac ctacaggtga aatgatcccc
3301 ctagcagtga ggatgggcac acatgcaacc atgagaatac agggtaggac cgttggtggc
3361 cagatgggaa tgctccttac aggggcaaat gcgaagaaca tggatcttgg caccggtcct
3421 ggtgactgcg gttgtcctta catctacaaa cgcggcaatg atatagttgt cgcgggtgtc
3481 cacaccgcag cagcccgggg gggcaacact gtcatatgtg ccactcaggg gcaagatggg
3541 gaggcagtcc ttgagggaaa tgagaacctt ggcacttact gcggtgcccc aattttgggc
3601 ccaggcaagg ctcccaagct tagcacgaag accaaattct ggcgttcatc accagacgtt
3661 ctgccgccag gcacttatga gcctgcctac ttgggaggca aggaccccag agtggaaaaa
3721 ggaccatccc tgcaacaagt catgagggac cagttgaaac ctttcacaga acccagaggc
3781 aagccaccta ggcctgcagt tttagaagaa gccaaaaaga cagtgatgaa tgttctagaa
3841 caaaccattg accctgctaa gccatggacc tattcccaag catgtgcctc actggacaag
3901 accacttcca gtggtagccc ccatcatgtc aagaaaaatg accattggaa tggggaatcc
3961 ttcactggcc cccttgcaga ccaagcatcc aaagccaacc tcatgtatga gcaggccaaa
4021 catgtgcagc ccgtgtacac ggccgcactc aaagatgaat tagtcaaaac tgacaagatc
4081 tacaaaaaga taaagaaaag gctcttatgg ggatcggatc ttggtacaat gatcaggtgt
4141 gccagggcct ttggtggtct catggatagc atgaaggcaa gttgcataac cctcccatgt
4201 agggtaggaa tgaacatgaa tgaagacggc cccatcatat ttgacaaaca ctctaagtat
4261 aggtaccatt atgatgctga ctattccagg tgggactcaa ctcagcaaag gagtgttctt
4321 gcagccgcta tggaagtgat ggtgcggttc tctgccgagc cagatctggc acaagtggtt
4381 gcggaggacc tcctggcacc cagccaacta gatgttggcg actttgtcat ctcagtccag
4441 gagggtctgc cgtcaggggt cccatgcaca tcacaatgga attcaatagc acattggatc
4501 ttgaccttga gcgcaatggc agaagtgtcg ggtctctcac cagatgtcgt gcaagcccac
4561 tcctgtttct cattctacgg tgatgatgag atcgtcagca ctgacatcaa ccttgacccc
4621 atgaagttga cccagaaact cagagagtat ggtttggttc ccactcgacc tgacaagact
4681 gagggttccc ttgtgataac tgaagatctc accggcctga cgttcctgcg taggtcaatt
4741 gcacgggacc cagccgggtg gtttggcaaa ttggaccaag actcaatcct cagacaattg
4801 tactggacaa ggggccccaa tcatgagaat ccatatgaga gcatggtccc ccattcccag
4861 cgggccacac agctcatggc tcttctcggt gaggcttcac tgcatggccc ccagttttac
4921 aagaaggtca gcaagatggt catcaacgag atcaaaagtg gtggtctgga attctatgtg
4981 cccagacaag aggccatgtt cagatggatg agattctctg acctcagcac atgggagggc
5041 gatcgcaatc ttgctcccga aggtgtgaat gaagatggcg tcgaatgacg ctgctccatc
5101 gaatgatggt gctgccaacc tcgtaccaga ggccaacaat gaggttatgg cacttgaacc
5161 ggtggtggga gcctcaatcg cagctcctgt cgtcggccaa caaaacataa ttgacccctg
5221 gattagagaa aattttgtcc aagcaccaca gggcgagttc accgtctcac cgaggaactc
5281 acctggagag atgctgttaa atcttgaatt gggcccagaa cttaaccctt acctaagtca
5341 cctgtcccgt atgtataatg ggtatgctgg tggcatgcag gttcaggtgg tcctagctgg
5401 gaacgcgttc acagctggaa aaatcatctt tgccgccgtg ccaccacact ttcccgtaga
5461 aaacatcagt gcagcccaaa taactatgtg cccccatgtg attgttgatg tgagacaact
5521 tgaaccagta cttctgcccc ttcctgacat taggaacagg ttctttcatt acaaccagga
5581 gaacactccc cggatgagac ttgtggccat gctctacacc cccctgaggg ccaactctgg
5641 tgaagatgtg ttcaccgtct cttgtcgggt tctgacccgt cctgcccctg attttgaatt
5701 cactttcttg gtaccaccaa ctgttgaatc aaagactaaa ccttttacac tgcccatact
5761 aactcttggt gaactgtcta attccaggtt cccagcccca atagacatgt tgtacactga
5821 cccgaatgag ggaatcgtgg tccaaccaca aaatggcagg tgcactcttg atggcaccct
5881 gcaaggcacc acacagctgg tccccaccca aatttgtgct tttaggggca cactaattag
5941 ccaaacatca agatcttcag actcaaccga ctcagcccct cggagaaggg atcacccact
6001 ccatgtgcaa ttaaagaacc ttgatggcac gcagtacgac ccaactgatg aagtgccagc
6061 agcccttggt gccattgact tcaaggggac tgtctttggt gtggccagtc agagagacgt
6121 gtcagggcaa caagtgggag cgactcgagc ccatgaagtg catgtcaaca caactgatcc
6181 taggtatgca ccaaaactgg gaaccatcct catgcactca gagtcggacg actttgtgac
6241 tgggcagccg atctgcttca cacccatagg aatgggtgac aacgactggc accagtggga
6301 actgcctgac tactctggac atctaaccct gaacatgaac ctcgccccag cagtcgctcc
6361 tgcttttccg ggtgagagga ttcttttctt cagatcagta gtcccgtctg ccggcggcta
6421 tgggtctgga caaatagact gcctcatacc acaggagtgg gttcagcact tctatcagga
6481 ggctgcacca tcccaatctg ccgtggcact cattaggtat gtcaatcctg acacaggcag
6541 aaacatcttt gaggctaaat tgcacaggga gggcttcatc accgtggcaa attctggtaa
6601 caatcctatt gttgtccccc ctaatgggta ttttaggttt gaggcttggg tgaatcaatt
6661 ttacactttg acccccatgg gaactggtca ggggcgtagg aggaatcaat aatggctagt
6721 gcttttcttg caggtcttgc tggcgacgcc ataacaaatg gcgttggatc tctaataaat
6781 gctggagcta atgcaatcaa tcagaaagtt gaatatgatt ttaacaaaca gcttcaaatg
6841 gcatcattta aacatgataa agagatgttg caatcacaag tgttggcaac caagcagttg
6901 cagcaggaga tgatgaacat aaggcagggg gtgttgaccg ctggcggctt ctcccccgca
6961 gatgctgcta gaggggccgt taatgcccca atgacaaaga ttctggactg gagtggcacc
7021 aggtattggg caccaaacag catgaaaacc acaagttatt caggacagtt ttctagcagc
7081 cctgttcata agtctcctgc tccttcccag catgctgttc cgtcaaagag taggttgcaa
7141 agtgattctg ttagtgtata tagctcccct tcctctgttt cttcacaatc aacccaatca
7201 acagtgctgt catcaggaac taggtcttcc aggtccatct ccacatctac agcgaccccc
7261 accttgtcta gaaccagcga ctgggttagg ggacagaatg agaggctcag cccgtttatg
7321 gatggtgctc tccaaactgc ctttgtcaca cctccatcga gcaaagcctc ttcaaatggt
7381 acggtctcaa ccgttcccaa agctgttttg gactcctgga cccctatgtt taacacacat
7441 aggcagcctc tcttcgccca tctacgcagg cgaggggagt cacaaattta gtgaaaagat
7501 tgattagatt ttctctccct acttcttttc tctc
//