Typing tool
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Typing tool
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Complete norovirus genomes
| MK236610 | GI.6 | |
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| GI.P11 |
ORF1: 1..5351
ORF2: 5335..6957
ORF3: 6957..7586
LOCUS MK236610 7674 bp RNA linear VRL 30-JAN-2019
DEFINITION Norovirus GI isolate NVRL17W01257 nonstructrual polyprotein (ORF1)
gene, partial cds; and VP2 (ORF2) and VP3 (ORF3) genes, complete
cds.
ACCESSION MK236610
VERSION MK236610.1
DBLINK BioProject: PRJNA490520
KEYWORDS .
SOURCE Norovirus GI
ORGANISM Norovirus GI
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7674)
AUTHORS Yang,Z. and Coughlan,S.
CONSRTM Oarsa, Cfsan, Fda
TITLE Direct Submission
JOURNAL Submitted (21-NOV-2018) OARSA, FDA, CFSAN, 8301 Muirkirk Rd.,
Laurel, MD 20708, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.1
Coverage :: 54
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7674
/organism="Norovirus GI"
/mol_type="genomic RNA"
/isolate="NVRL17W01257"
/isolation_source="feces"
/host="Homo sapiens; female"
/db_xref="taxon:122928"
/country="Ireland"
/collection_date="14-Dec-2016"
/note="genotype: GI"
gene <1..5351
/gene="ORF1"
CDS <1..5351
/gene="ORF1"
/codon_start=3
/product="nonstructrual polyprotein"
/protein_id="QAT98927.1"
/translation="DVVATNVASNNNANNTSVTSRFLSRFKGLGGGASPPNPIKIKST
EMALGLIGKTAQEAVGASDLPPKQQRDRPPRTQEEVQYGMGWTERPVDQNVKSWEELD
TSTKEEILDSHKEWFDAGGLGPCTMPSTCEQAKDDSPPGEQVRWSVRDGVNLGVNRLT
TVNGPEWNLCPLPPIDLRNMEPASEPTIGDMIEFYEGHIYHYSIYIGQGKTVGVHSPQ
AAFSVARVTIQPIAAWWRVCYIPQPKHRLSYDQLRELENEPWPYAAITNNCFEFCCQV
MNLEDTWLQRRLITSGRFHHPSQSWSQQTPEFQQDSKLELVRDAILAAVNGLVSQPFK
NFLGKLKPLNVLNILSNCDWTFMGVVEMVILLLELFGVFWNPPDVSNFIASLLPDFHL
QGPEDLARDLVPVILGGIGLAIGFTRDKVTKVMKSAVDGLRAATQLGQYGLEIFSLLK
KYFFGGDQTERTLKGIETAVIDMEVLSSTSVTQLVRDKQAAKAYMNILDNEEEKARKL
SAKNADPHVISSTNALISRIAMARSALAKAQAEMTSRMRPVVIMMCGPPGIGKTKAAE
HLAKRLANEIRPGGKVGLVPREAVDHWDGYHGEEVMLWDDYGMTKIQDDCNKLQAIAD
SAPLTLNCDRIENKGMQFVSDAIVITTNAPGPAPVDFVNLGPVCRRVDFLVYCSAPEV
EQIRRVSPGDTSALKDCFKSDFSHLKMELAPQGGFDNQGNTPFGKGVMKPTTINRLLI
QAVALTMERQDEFRLQGKMYDFDDDRVSAFTTMARDNGLGILSMASLGKKLRGVTSMD
GLKNALKGYKIGACTIKWQAKVYSLESDGNSVNIREEKNVLTQQQQSVCAASIALTRL
RAARAVAYASCIQSAITSILQIAASALVVNRAVKRMFGTRTAALSLEGPPKEHKCRVH
QAKAAGKGPIGHDDMVDKYGLCETEEDEEVVHTEIPSATMEGKNKGKNKKGRGRKNNY
NAFSRRGLNDEEYEEYKKIREEKGGNYSIQEYLEDRQRYEEELAEVQAGGDGGIGETE
MEIRHRVFYKSKSKKHHQEERRQLGLVTGSDIRKRKPIDWTPPKSAWADDEREVDYNE
RINFEAPPTLWSRVTKFGSGWGFWVSPTVFITTTHVIPTSAKEFFGEPLASIAIHRAG
EFTLFRFSKKIRPDLTGMILEEGCPEGTVCSVLIKRDSGELLPLAVRMGAIASMRIQG
RLVHGQSGMLLTGANAKGMDLGTIPGDCGAPYVYKRANDWVVCGVHAAATKSGNTVVC
AVQASEGETTLEGGDKGHYAGHEIIKHGCGPALSTKTKFWKSSPEPLPPGVYEPAYLG
GRDPRVSGGPSLQQVLRDQLKPFAEPRGRMPEPGLLEAAVETVTSSLEQVMDTPVPWS
YSDACQSLDKTTSSGFPHHKKKNDDWNGTAFIRELGEQAAHANNMYEQAKSMKPMYTA
ALKDELVKPEKVYQKVKKRLLWGADLGTVIRAARAFGPFCDAIKSHTIKLPIKVGMNS
IEDGPLIYAEHSKYKYHFDADYTAWDSTQNRQIMTESFSIMCRLTASPELASVVAQDL
LAPSEMDVGDYVIRVKEGLPSGFPCTSQVNSINHWLITLCALSEVTGLSPDVIQSMSY
FSFYGDDEIVSTDIEFDPAKLTQVLKEYGLKPTRPDKSEGPIIVRKSVDGLVFLRRTI
SRDAAGFQGRLDRASIERQIYWTRGPNHSDPFETLVPHQQRKIQLISLLGEASLHGEK
FYRKISSKVIQEIKTGGLEMYVPGWQAMFRWMRFHDLGLWTGDRNLLPEFVNDDGV"
gene 5335..6957
/gene="ORF2"
CDS 5335..6957
/gene="ORF2"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QAT98928.1"
/translation="MMMASKDAPTSPDGASGAGQLVPEANTAEQISMDPVAGASTAVA
TAGQVNMIDPWIFNNFVQAPQGEFTISPNNTPGDILFDLQLGPHLNPFLAHLSQMYNG
WVGNMRVRILLAGNAFTAGKIIICCVPPGFDARILTIAQATLFPHLIADVRTLEPVEL
PLEDVRNVLFHNSSQPQPTMRLVAMLYTPLRTGGGSGGTDAFVVAGRVLTCPAPDFSF
LFLVPPSVEQKTRVFSVPNIPLKDLSNSRVPVPVQGMFMSPDVNQSVQFQNGRCQIDG
QLQGTTPVSLSQLCKIRGKTSSNARVLNLSEVDGTPFIPLESPAPVGFPDLGGCDWHV
NFTFQAQNQDPSQSVTFATNDASFVPYLGSISPHNGGDFHAGDIIGSLGWISAPSDNS
QLNVWTIPKYGSSLPDVTHLAPAVFPPGFGEVILYFYSTFPGSGQSSQLQVPCLLPQE
FITHFCNEQAPIAGEAALLHYVDPDTGRNLGEFKLYPDGFMTCVPNSVSSGPQTLPIN
GVFVFVSWVSRFYQLKPVGTASAARRLGLRRI"
gene 6957..7586
/gene="ORF3"
CDS 6957..7586
/gene="ORF3"
/codon_start=1
/product="VP3"
/protein_id="QAT98929.1"
/translation="MAQAVIGAIAASAAGSILGAGIQAGAEAGLQAQRYQQDLQLQQN
SFKHDKEMLGYQVQASNALLAKNLNTRYALLQAGGLSSADAARAVAGAPVTRIVDWNG
TRIAAPTSSTTTLRSGGFMAVPIPLSSKTKQPVMSGQDNPNYAASSISRTASWVQSQN
SMRSVSPFHSDALRTVWVTPPGSSSTSSVQSSFYGVFNTDRLPLFANRR"
ORIGIN
1 aagacgtcgt tgcgactaat gttgcaagca ataacaacgc taacaacact agtgttacat
61 ctcgatttct gtcgagattt aagggtttag gtggtggcgc gagcccccct aaccccataa
121 agatcaaaag cacagaaatg gccttgggtt tgattggcaa gacagcccaa gaggcagtag
181 gtgccagtga cctaccgccc aaacagcaaa gagatcggcc ccccagaacc caggaggaag
241 ttcagtacgg catggggtgg actgaaaggc ccgtggacca gaatgttaag tcatgggagg
301 aacttgacac ctccaccaag gaagaaattt tggacagcca caaagaatgg ttcgacgccg
361 gcggtttggg cccgtgcacc atgccctcaa cttgtgaaca ggctaaagat gacagcccac
421 ctggtgagca agtcagatgg tcagtgcgtg atggagtcaa ccttggagtg aaccgtctca
481 cgacagtgaa tggccccgag tggaacctct gccctttacc ccccattgac ctaaggaata
541 tggaaccagc cagtgaaccc accattggag acatgataga gttttatgaa ggccacatct
601 accactactc catatacatt gggcaaggga agacagttgg tgttcattcc ccacaggcag
661 cattctcagt ggctagagta accatccaac ctatagctgc ttggtggagg gtttgttata
721 taccccagcc caaacataga ctgagttatg accaacttag ggaattggaa aatgaaccct
781 ggccatatgc agctatcacc aacaattgtt ttgagttttg ttgtcaagtc atgaatcttg
841 aggacacatg gttgcagagg cggctaataa catcaggtag attccaccat ccttcccagt
901 cttggtcaca acagacccct gaatttcagc aggacagtaa actggagctg gttagggatg
961 ccatactggc cgcagtgaat ggccttgtct cacaaccctt caagaatttc ttgggcaagc
1021 tcaagcctct taatgtatta aacatcctat ctaactgtga ctggactttt atgggggtgg
1081 tagagatggt tatactactt cttgagctct ttggcgtgtt ctggaacccg cccgatgtgt
1141 ctaattttat agcatctctc ctccctgact tccacctcca gggaccagaa gacctggccc
1201 gggatttggt gccagtcatt cttggtggca taggactagc cattggattt accagagata
1261 aagtcaccaa ggtcatgaag agtgctgtgg atggactccg ggccgctaca cagctggggc
1321 aatacgggtt ggaaatattc tcactcctca aaaagtattt ctttggtggg gatcagaccg
1381 aacggaccct caaaggcatt gaaacagcag tcatagacat ggaggttttg tcctccacat
1441 cagtgacaca actggtgaga gacaagcagg cagctaaagc ttacatgaac atcctggata
1501 atgaagagga aaaggctaga aaactctctg ctaagaatgc tgacccccat gtaatatcct
1561 caacaaatgc cctaatatca cgtatagcca tggcgcgatc cgctctggct aaggctcagg
1621 ctgagatgac cagccgaatg aggccagttg tcatcatgat gtgtggaccc cctggaattg
1681 gtaaaactaa agcagcggag cacttggcaa aacgcctagc taatgagatc aggcctggtg
1741 gcaaagtggg actggtacca cgtgaggctg ttgaccactg ggatggctac catggtgagg
1801 aagtgatgct atgggatgac tatggtatga caaagataca agatgactgc aacaagctcc
1861 aggctattgc tgactctgcc ccactcactc tcaattgtga taggattgaa aataaaggga
1921 tgcagtttgt gtcagatgca atagtcatca ccaccaacgc tccagggcct gcccctgtgg
1981 actttgtcaa ccttggccct gtgtgtagac gggttgactt cctggtctac tgttccgccc
2041 cagaggtaga gcagataagg agagtcagcc ctggagacac gtcggcactt aaagactgct
2101 tcaagtcaga tttctcccac ctgaagatgg agttagctcc tcaagggggg tttgacaacc
2161 aggggaacac accattcggc aagggtgtca tgaaaccaac aaccatcaac aggctcctca
2221 tacaagctgt ggctctcacc atggagagac aggatgagtt ccgtctccaa gggaagatgt
2281 atgattttga tgatgatagg gtgtcagcct ttaccaccat ggcacgcgat aacggattgg
2341 gcatcctgag tatggcgagc ctaggtaaga agctgcgcgg tgtcacatcg atggatggcc
2401 tgaagaatgc tttgaaaggg tataaaattg gtgcgtgcac aatcaagtgg caggccaagg
2461 tgtattcact agagtcagat ggcaacagcg ttaacatcag ggaggagaag aatgtcttga
2521 ctcaacaaca gcagtcggtg tgcgctgcct ctattgcact cacccgtctg cgggccgcac
2581 gcgcggtggc gtatgcgtca tgcattcaat cagccataac ctccatacta caaattgctg
2641 cctctgccct agtggtcaac agggccgtga aaagaatgtt tggcacacgc actgctgctt
2701 tgtctctaga gggccccccc aaagaacaca aatgcagagt ccaccaggct aaagccgcag
2761 gaaaagggcc cattggccat gatgacatgg ttgataaata tggcctatgc gagactgagg
2821 aggatgaaga agtagtccac actgagatac catctgccac catggaaggt aagaacaaag
2881 gaaagaacaa gaaagggcgc ggccgaaaga acaactacaa cgccttttcc cgtagggggc
2941 tcaatgacga agagtacgag gagtacaaga aaatacggga agagaagggt ggaaattaca
3001 gcattcagga gtacctagag gatagacaaa gatatgaaga ggagcttgct gaggttcaag
3061 caggtggaga tggaggaatc ggtgaaactg aaatggaaat ccgccacaga gtgttctaca
3121 agtctaagag taagaagcac caccaggaag aacgacgcca actggggtta gtcacaggtt
3181 ctgacatccg gaaaagaaaa ccaattgact ggaccccccc taagtcagca tgggcagatg
3241 atgagcgtga agtggactac aatgagagga tcaactttga ggcgcccccc accttgtgga
3301 gccgggtcac aaagtttgga tctgggtggg gcttctgggt cagtcccaca gtcttcataa
3361 ccacaacgca cgttatacca accagtgcaa aagagttctt tggtgaaccc cttgccagca
3421 tagccatcca tagagccgga gaattcaccc tcttcaggtt ctctaagaaa atcaggcccg
3481 atctcacggg tatgattctt gaggaaggtt gcccagaggg cacggtgtgc tcagtattaa
3541 taaaaaggga ctccggtgag ctactaccac tggctgtaag aatgggcgca atagcatcaa
3601 tgcgcataca gggtcgcctt gtccatggcc agtctggtat gttgctcact ggggcgaatg
3661 ctaaaggcat ggacctcgga actattccag gggattgtgg agctccctat gtctataaga
3721 gagcaaatga ctgggtggtt tgtggtgtgc acgctgctgc cactaaatca ggcaacacgg
3781 tagtgtgtgc cgtccaggct agtgaagggg aaaccacact tgaggggggt gacaaaggtc
3841 actacgccgg acatgagata atcaagcatg gatgtgggcc agccctgtca accaaaacaa
3901 agttctggaa atcgtcccct gaaccactgc cccctggagt ctatgaacct gcatacctcg
3961 gtggtcggga tccaagagtg agtggtggcc cctcgctcca acaggtatta cgggatcagt
4021 taaaaccatt tgctgagcca cgtgggcgta tgccggaacc aggtctcctg gaggccgcag
4081 ttgagactgt gacctcatca ctggagcagg ttatggatac cccagtgcca tggagttaca
4141 gcgatgcatg tcaatcccta gataaaacta ctagctctgg ttttccccat cacaagaaga
4201 agaatgatga ttggaacggc accgccttca ttagggagtt gggagagcag gcagcgcacg
4261 ccaataatat gtacgaacaa gctaagagca tgaagcccat gtacacggcg gcgcttaagg
4321 atgaattagt gaaaccagaa aaagtgtacc aaaaagtgaa gaagcgcttg ctttggggag
4381 cagatctagg aacagtgatc cgggccgcac gggcctttgg cccattctgt gatgccataa
4441 aatcccacac aattaaatta cctatcaaag ttggaatgaa ttcaattgag gatgggccat
4501 taatttatgc agagcattca aaatataaat atcactttga tgcagactat acggcttggg
4561 actcaacaca aaataggcaa attatgactg aatcattctc aatcatgtgt cggctaactg
4621 cttctccaga attggcatca gtggtggcac aagatcttct tgcaccctca gaaatggacg
4681 ttggcgacta cgtcataaga gtgaaggaag gcctcccatc tggcttccca tgcacatcac
4741 aagtcaatag cataaaccat tggttgataa cattgtgcgc cctctctgag gtgactggcc
4801 tgtcaccaga tgttatccag tccatgtcat acttttcttt ttatggtgat gatgaaatag
4861 tttccactga catagaattt gacccagcaa agctgacaca agtccttaaa gagtatggcc
4921 tcaaacccac ccgccctgac aagagtgaag gtccaataat tgtgaggaag agtgtggatg
4981 gcctggtctt cttacgtcgc accatttccc gcgacgccgc ggggttccag gggcgactgg
5041 atcgtgcatc cattgaaagg cagatctact ggaccagagg gcccaatcac tcagacccct
5101 ttgaaacctt ggtgccccac cagcaaagaa aaatccagct gatatcactg ttaggtgagg
5161 cctcattgca tggtgaaaaa ttctacagga agatctcaag taaagtcatc caagagatta
5221 agacaggggg tcttgaaatg tatgtgccag ggtggcaagc catgttccgc tggatgcggt
5281 tccacgacct tggcctgtgg acaggagatc gcaatctcct gcccgaattc gtaaatgatg
5341 atggcgtcta aggacgcccc aacatcccct gatggcgcca gtggcgccgg ccagctggta
5401 ccggaggcta atacagctga gcaaatttca atggaccctg ttgcgggtgc ttcaacagca
5461 gtcgcgacag ctgggcaagt taacatgatt gacccatgga ttttcaataa cttcgtccag
5521 gcacctcaag gagaattcac tatttcccct aataataccc ccggtgatat tttgtttgat
5581 ttacaactag gaccccacct taacccattt ctagcccatc tctcacagat gtacaatggt
5641 tgggtcggca atatgcgtgt gcgcatactg ttggccggga atgccttcac agctggaaag
5701 ataatcattt gctgtgtccc ccctggtttt gatgccagaa tactcacaat agctcaagca
5761 actctcttcc cacacttaat tgctgatgta aggacccttg agcctgtgga gcttcctttg
5821 gaggatgtgc gcaatgttct cttccacaac agtagccaac cgcagccaac aatgcggttg
5881 gttgctatgt tgtacactcc cctccgcact ggtggtggtt ccggaggcac tgatgccttt
5941 gtggtcgcgg gtagggtgct tacgtgcccc gcccccgact ttagttttct gtttctagtc
6001 cccccttccg ttgaacaaaa gaccagagtt ttcagtgtcc ccaacatacc cctgaaggat
6061 ctctcaaatt cccgtgtccc tgtgccagtg cagggcatgt ttatgtcccc agatgttaat
6121 cagtcagtcc agtttcagaa tggacgctgc caaattgatg gtcaactcca aggcaccact
6181 ccagtctcgc tcagccaact ctgcaagatt aggggtaaaa cttctagcaa tgctagggtg
6241 cttaacttaa gtgaggtgga tggcacaccc ttcatcccac ttgaatcacc agcgccagtt
6301 ggttttcccg acttgggagg ttgtgattgg catgtaaatt tcactttcca ggctcaaaat
6361 caggacccat ctcaaagtgt aacctttgca actaatgatg ctagctttgt cccctatcta
6421 ggtagtatct ctcctcacaa tgggggagat tttcatgcag gtgacatcat aggtagcctt
6481 ggttggattt cagccccgtc tgataattca caacttaatg tttggacaat accaaagtat
6541 ggatctagtc tcccagatgt cactcatctt gcccctgctg tgttcccccc aggctttggg
6601 gaggtgatct tgtacttcta ttctaccttc ccaggttctg gacaatccag ccaacttcaa
6661 gtcccatgct tgttgcctca ggagtttatc acccacttct gtaacgaaca ggctcccatc
6721 gctggggagg ctgccctcct ccactacgtg gaccctgata cggggcgaaa tttgggagaa
6781 ttcaaacttt accctgatgg gtttatgacc tgtgtcccca atagtgttag tagtggccct
6841 caaacccttc ctatcaatgg agtctttgtc tttgtttcat gggtatctag attctatcaa
6901 ctcaagcctg tgggaacggc ctcagcggct agaaggcttg gattgcggcg catataatgg
6961 cccaagctgt catcggtgcc atagccgcat ctgccgctgg tagcatacta ggggcaggca
7021 tacaggctgg tgctgaggct ggtctccagg ctcaacggta tcagcaggat ctgcagttgc
7081 aacaaaattc tttcaagcat gataaggaaa tgttaggtta ccaagttcag gctagtaatg
7141 ctctcttagc taagaatctt aacactagat atgctcttct gcaggcaggg ggcctatcta
7201 gcgctgatgc tgctcgggca gtggctggtg ctcctgtcac ccgtatagtg gactggaatg
7261 gcacgcgcat tgcggcgccc acttcaagca ccactacact cagatctggt ggttttatgg
7321 ctgtccctat accattgtct tcaaagacca agcaaccagt gatgtctggg caggataatc
7381 caaattatgc tgcttcttct atctctagaa ctgcttcatg ggtgcaatct caaaattcta
7441 tgaggtctgt ttctcctttt cacagtgacg ctttgagaac cgtttgggtt acaccacccg
7501 gttcatcatc aacttcatct gtgcaatcta gtttctatgg tgtttttaat acagatagat
7561 tgcctctgtt cgcaaacaga aggtaataaa atttttgtaa taggatgcca gtgggcacca
7621 tattcagatt tggttaatta gattgttttt aattaaaatt tggcttaatt ggtg
//