Typing tool
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Typing tool
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Complete norovirus genomes
| MK236609 | GI.6 | |
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| GI.P11 |
ORF1: 1..5359
ORF2: 5343..6965
ORF3: 6965..7594
LOCUS MK236609 7674 bp RNA linear VRL 30-JAN-2019
DEFINITION Norovirus GI isolate NVRL17W01252 nonstructrual polyprotein (ORF1)
gene, partial cds; and VP2 (ORF2) and VP3 (ORF3) genes, complete
cds.
ACCESSION MK236609
VERSION MK236609.1
DBLINK BioProject: PRJNA490520
KEYWORDS .
SOURCE Norovirus GI
ORGANISM Norovirus GI
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7674)
AUTHORS Yang,Z. and Coughlan,S.
CONSRTM Oarsa, Cfsan, Fda
TITLE Direct Submission
JOURNAL Submitted (21-NOV-2018) OARSA, FDA, CFSAN, 8301 Muirkirk Rd.,
Laurel, MD 20708, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.1
Coverage :: 98
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7674
/organism="Norovirus GI"
/mol_type="genomic RNA"
/isolate="NVRL17W01252"
/isolation_source="feces"
/host="Homo sapiens; female"
/db_xref="taxon:122928"
/country="Ireland"
/collection_date="13-Dec-2016"
/note="genotype: GI"
gene <1..5359
/gene="ORF1"
CDS <1..5359
/gene="ORF1"
/codon_start=2
/product="nonstructrual polyprotein"
/protein_id="QAT98924.1"
/translation="ASKDVVATNVASNNNANNTSVTSRFLSRFKGLGGGASPPNPIKI
KSTEMALGLIGKTAQEAVGASDLPPKQQRDRPPRTQEEVQYGMGWTERPVDQNVKSWE
ELDTSTKEEILDSHKEWFDAGGLGPCTMPSTCEQAKDDSPPGEQVRWSVRDGVNLGVN
RLTTVNGPEWNLCPLPPIDLRNMEPASEPTIGDMIEFYEGHIYHYSIYIGQGKTVGVH
SPQAAFSVARVTIQPIAAWWRVCYIPQPKHRLSYDQLRELENEPWPYAAITNNCFEFC
CQVMNLEDTWLQRRLITSGRFHHPSQSWSQQTPEFQQDSKLELVRDAILAAVNGLVSQ
PFKNFLGKLKPLNVLNILSNCDWTFMGVVEMVILLLELFGVFWNPPDVSNFIASLLPD
FHLQGPEDLARDLVPVILGGIGLAIGFTRDKVTKVMKSAVDGLRAATQLGQYGLEIFS
LLKKYFFGGDQTERTLKGIETAVIDMEVLSSTSVTQLVRDKQAAKAYMNILDNEEEKA
RKLSAKNADPHVISSTNALISRIAMARSALAKAQAEMTSRMRPVVIMMCGPPGIGKTK
AAEHLAKRLANEIRPGGKVGLVPREAVDHWDGYHGEEVMLWDDYGMTKIQDDCNKLQA
IADSAPLTLNCDRIENKGMQFVSDAIVITTNAPGPAPVDFVNLGPVCRRVDFLVYCSA
PEVEQIRRVSPGDTSALKDCFKSDFSHLKMELAPQGGFDNQGNTPFGKGVMKPTTINR
LLIQAVALTMERQDEFRLQGKMYDFDDDRVSAFTTMARDNGLGILSMASLGKKLRGVT
SMDGLKNALKGYKIGACTIKWQAKVYSLESDGNSVNIREEKNVLTQQQQSVCAASIAL
TRLRAARAVAYASCIQSAITSILQIAASALVVNRAVKRMFGTRTAALSLEGPPKEHKC
RVHQAKAAGKGPIGHDDMVDKYGLCETEEDEEVVHTEIPSATMEGKNKGKNKKGRGRK
NNYNAFSRRGLNDEEYEEYKKIREEKGGNYSIQEYLEDRQRYEEELAEVQAGGDGGIG
ETEMEIRHRVFYKSKSKKHHQEERRQLGLVTGSDIRKRKPIDWTPPKSAWADDEREVD
YNERINFEAPPTLWSRVTKFGSGWGFWVSPTVFITTTHVIPTSAKEFFGEPLASIAIH
RAGEFTLFRFSKKIRPDLTGMILEEGCPEGTVCSVLIKRDSGELLPLAVRMGAIASMR
IQGRLVHGQSGMLLTGANAKGMDLGTIPGDCGAPYVYKRANDWVVCGVHAAATKSGNT
VVCAVQASEGETTLEGGDKGHYAGHEIIKHGCGPALSTKTKFWKSSPEPLPPGVYEPA
YLGGRDPRVSGGPSLQQVLRDQLKPFAEPRGRMPEPGLLEAAVETVTSSLEQVMDTPV
PWSYSDACQSLDKTTSSGFPHHKKKNDDWNGTAFIRELGEQAAHANNMYEQAKSMKPM
YTAALKDELVKPEKVYQKVKKRLLWGADLGTVIRAARAFGPFCDAIKSHTIKLPIKVG
MNSIEDGPLIYAEHSKYKYHFDADYTAWDSTQNRQIMTESFSIMCRLTASPELASVVA
QDLLAPSEMDVGDYVIRVKEGLPSGFPCTSQVNSINHWLITLCALSEVTGLSPDVIQS
MSYFSFYGDDEIVSTDIEFDPAKLTQVLKEYGLKPTRPDKSEGPIIVRKSVDGLVFLR
RTISRDAAGFQGRLDRASIERQIYWTRGPNHSDPFETLVPHQQRKIQLISLLGEASLH
GEKFYRKISSKVIQEIKTGGLEMYVPGWQAMFRWMRFHDLGLWTGDRNLLPEFVNDDG
V"
gene 5343..6965
/gene="ORF2"
CDS 5343..6965
/gene="ORF2"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QAT98925.1"
/translation="MMMASKDAPTSPDGASGAGQLVPEANTAEQISMDPVAGASTAVA
TAGQVNMIDPWIFNNFVQAPQGEFTISPNNTPGDILFDLQLGPHLNPFLAHLSQMYNG
WVGNMRVRILLAGNAFTAGKIIICCVPPGFDARILTIAQATLFPHLIADVRTLEPVEL
PLEDVRNVLFHNSSQPQPTMRLVAMLYTPLRTGGGSGGTDAFVVAGRVLTCPAPDFSF
LFLVPPSVEQKTRVFSVPNIPLKDLSNSRVPVPVQGMFMSPDVNQSVQFQNGRCQIDG
QLQGTTPVSLSQLCKIRGKTSSNARVLNLSEVDGTPFIPLESPAPVGFPDLGGCDWHV
NFTFQAQNQDPSQSVTFATNDASFVPYLGSISPHNGGDFHAGDIIGSLGWISAPSDNS
QLNVWTIPKYGSSLPDVTHLAPAVFPPGFGEVILYFYSTFPGSGQSSQLQVPCLLPQE
FITHFCNEQAPIAGEAALLHYVDPDTGRNLGEFKLYPDGFMTCVPNSVSSGPQTLPIN
GVFVFVSWVSRFYQLKPVGTASAARRLGLRRI"
gene 6965..7594
/gene="ORF3"
CDS 6965..7594
/gene="ORF3"
/codon_start=1
/product="VP3"
/protein_id="QAT98926.1"
/translation="MAQAVIGAIAASAAGSILGAGIQAGAEAGLQAQRYQQDLQLQQN
SFKHDKEMLGYQVQASNALLAKNLNTRYALLQAGGLSSADAARAVAGAPVTRIVDWNG
TRIAAPTSSTTTLRSGGFMAVPIPLSSKTKQPVMSGQDNPNYAASSISRTASWVQSQN
SMRSVSPFHSDALRTVWVTPPGSSSTSSVQSSFYGVFNTDRLPLFANRR"
ORIGIN
1 ggcgtcgaaa gacgtcgttg cgactaatgt tgcaagcaat aacaacgcta acaacactag
61 tgttacatct cgatttctgt cgagatttaa gggtttaggt ggtggcgcga gcccccctaa
121 ccccataaag atcaaaagca cagaaatggc cttgggtttg attggcaaga cagcccaaga
181 ggcagtaggt gccagtgacc taccgcccaa acagcaaaga gatcggcccc ccagaaccca
241 ggaggaagtt cagtacggca tggggtggac tgaaaggccc gtggaccaga atgttaagtc
301 atgggaggaa cttgacacct ccaccaagga agaaattttg gacagccaca aagaatggtt
361 cgacgccggc ggtttgggcc cgtgcaccat gccctcaact tgtgaacagg ctaaagatga
421 cagcccacct ggtgagcaag tcagatggtc agtgcgtgat ggagtcaacc ttggagtgaa
481 ccgtctcacg acagtgaatg gccccgagtg gaacctctgc cctttacccc ccattgacct
541 aaggaatatg gaaccagcca gtgaacccac cattggagac atgatagagt tttatgaagg
601 ccacatctac cactactcca tatacattgg gcaagggaag acagttggtg ttcattcccc
661 acaggcagca ttctcagtgg ctagagtaac catccaacct atagctgctt ggtggagggt
721 ttgttatata ccccagccca aacatagact gagttatgac caacttaggg aattggaaaa
781 tgaaccctgg ccatatgcag ctatcaccaa caattgtttt gagttttgtt gtcaagtcat
841 gaatcttgag gacacatggt tgcagaggcg gctaataaca tcaggtagat tccaccatcc
901 ttcccagtct tggtcacaac agacccctga atttcagcag gacagtaaac tggagctggt
961 tagggatgcc atactggccg cagtgaatgg ccttgtctca caacccttca agaatttctt
1021 gggcaagctc aagcctctta atgtattaaa catcctatct aactgtgact ggacttttat
1081 gggggtggta gagatggtta tactacttct tgagctcttt ggcgtgttct ggaacccgcc
1141 cgatgtgtct aattttatag catctctcct ccctgacttc cacctccagg gaccagaaga
1201 cctggcccgg gatttggtgc cagtcattct tggtggcata ggactagcca ttggatttac
1261 cagagataaa gtcaccaagg tcatgaagag tgctgtggat ggactccggg ccgctacaca
1321 gctggggcaa tacgggttgg aaatattctc actcctcaaa aagtatttct ttggtgggga
1381 tcagaccgaa cggaccctca aaggcattga aacagcagtc atagacatgg aggttttgtc
1441 ctccacatca gtgacacaac tggtgagaga caagcaggca gctaaagctt acatgaacat
1501 cctggataat gaagaggaaa aggctagaaa actctctgct aagaatgctg acccccatgt
1561 aatatcctca acaaatgccc taatatcacg tatagccatg gcgcgatccg ctctggctaa
1621 ggctcaggct gagatgacca gccgaatgag gccagttgtc atcatgatgt gtggaccccc
1681 tggaattggt aaaactaaag cagcggagca cttggcaaaa cgcctagcta atgagatcag
1741 gcctggtggc aaagtgggac tggtaccacg tgaggctgtt gaccactggg atggctacca
1801 tggtgaggaa gtgatgctat gggatgacta tggtatgaca aagatacaag atgactgcaa
1861 caagctccag gctattgctg actctgcccc actcactctc aattgtgata ggattgaaaa
1921 taaagggatg cagtttgtgt cagatgcaat agtcatcacc accaacgctc cagggcctgc
1981 ccctgtggac tttgtcaacc ttggccctgt gtgtagacgg gttgacttcc tggtctactg
2041 ttccgcccca gaggtagagc agataaggag agtcagccct ggagacacgt cggcacttaa
2101 agactgcttc aagtcagatt tctcccacct gaagatggag ttagctcctc aaggggggtt
2161 tgacaaccag gggaacacac cattcggcaa gggtgtcatg aaaccaacaa ccatcaacag
2221 gctcctcata caagctgtgg ctctcaccat ggagagacag gatgagttcc gtctccaagg
2281 gaagatgtat gattttgatg atgatagggt gtcagccttt accaccatgg cacgcgataa
2341 cggattgggc atcctgagta tggcgagcct aggtaagaag ctgcgcggtg tcacatcgat
2401 ggatggcctg aagaatgctt tgaaagggta taaaattggt gcgtgcacaa tcaagtggca
2461 ggccaaggtg tattcactag agtcagatgg caacagcgtt aacatcaggg aggagaagaa
2521 tgtcttgact caacaacagc agtcggtgtg cgctgcctct attgcactca cccgtctgcg
2581 ggccgcacgc gcggtggcgt atgcgtcatg cattcaatca gccataacct ccatactaca
2641 aattgctgcc tctgccctag tggtcaacag ggccgtgaaa agaatgtttg gcacacgcac
2701 tgctgctttg tctctagagg gcccccccaa agaacacaaa tgcagagtcc accaggctaa
2761 agccgcagga aaagggccca ttggccatga tgacatggtt gataaatatg gcctatgcga
2821 gactgaggag gatgaagaag tagtccacac tgagatacca tctgccacca tggaaggtaa
2881 gaacaaagga aagaacaaga aagggcgcgg ccgaaagaac aactacaacg ccttttcccg
2941 tagggggctc aatgacgaag agtacgagga gtacaagaaa atacgggaag agaagggtgg
3001 aaattacagc attcaggagt acctagagga tagacaaaga tatgaagagg agcttgctga
3061 ggttcaagca ggtggagatg gaggaatcgg tgaaactgaa atggaaatcc gccacagagt
3121 gttctacaag tctaagagta agaagcacca ccaggaagaa cgacgccaac tggggttagt
3181 cacaggttct gacatccgga aaagaaaacc aattgactgg acccccccta agtcagcatg
3241 ggcagatgat gagcgtgaag tggactacaa tgagaggatc aactttgagg cgccccccac
3301 cttgtggagc cgggtcacaa agtttggatc tgggtggggc ttctgggtca gtcccacagt
3361 cttcataacc acaacgcacg ttataccaac cagtgcaaaa gagttctttg gtgaacccct
3421 tgccagcata gccatccata gagccggaga attcaccctc ttcaggttct ctaagaaaat
3481 caggcccgat ctcacgggta tgattcttga ggaaggttgc ccagagggta cggtgtgctc
3541 agtattaata aaaagggact ccggtgagct actaccactg gctgtaagaa tgggcgcaat
3601 agcatcaatg cgcatacagg gtcgccttgt ccatggccag tctggtatgt tgctcactgg
3661 ggcgaatgct aaaggcatgg acctcggaac tattccaggg gattgtggag ctccctatgt
3721 ctataagaga gcaaatgact gggtggtttg tggtgtgcac gctgctgcca ctaaatcagg
3781 caacacggta gtgtgtgccg tccaggctag tgaaggggaa accacacttg aggggggtga
3841 caaaggtcac tacgccggac atgagataat caagcatgga tgtgggccag ccctgtcaac
3901 caaaacaaag ttctggaaat cgtcccctga accactgccc cctggagtct atgaacctgc
3961 atacctcggt ggtcgggatc caagagtgag tggtggcccc tcgctccaac aggtattacg
4021 ggatcagtta aaaccatttg ctgagccacg tgggcgtatg ccggaaccag gtctcctgga
4081 ggccgcagtt gagactgtga cctcatcact ggagcaggtt atggataccc cagtgccatg
4141 gagttacagc gatgcatgtc aatccctaga taaaactact agctctggtt ttccccatca
4201 caagaagaag aatgatgatt ggaacggcac cgccttcatt agggagttgg gagagcaggc
4261 agcgcacgcc aataatatgt acgaacaagc taagagcatg aagcccatgt acacggcggc
4321 gcttaaggat gaattagtga aaccagaaaa agtgtaccaa aaagtgaaga agcgcttgct
4381 ttggggagca gatctaggaa cagtgatccg ggccgcacgg gcctttggcc cattctgtga
4441 tgccataaaa tcccacacaa ttaaattacc tatcaaagtt ggaatgaatt caattgagga
4501 tgggccatta atttatgcag agcattcaaa atataaatat cactttgatg cagactatac
4561 ggcttgggac tcaacacaaa ataggcaaat tatgactgaa tcattctcaa tcatgtgtcg
4621 gctaactgct tctccagaat tggcatcagt ggtggcacaa gatcttcttg caccctcaga
4681 aatggacgtt ggcgactacg tcataagagt gaaggaaggc ctcccatctg gcttcccatg
4741 cacatcacaa gtcaatagca taaaccattg gttgataaca ttgtgcgccc tctctgaggt
4801 gactggcctg tcaccagatg ttatccagtc catgtcatac ttttcttttt atggtgatga
4861 tgaaatagtt tccactgaca tagaatttga cccagcaaag ctgacacaag tccttaaaga
4921 gtatggcctc aaacccaccc gccctgacaa gagtgaaggt ccaataattg tgaggaagag
4981 tgtggatggc ctggtcttct tacgtcgcac catttcccgc gacgccgcgg ggttccaggg
5041 gcgactggat cgtgcatcca ttgaaaggca gatctactgg accagagggc ccaatcactc
5101 agaccccttt gaaaccttgg tgccccacca gcaaagaaaa atccagctga tatcactgtt
5161 aggtgaggcc tcattgcatg gtgaaaaatt ctacaggaag atctcaagta aagtcatcca
5221 agagattaag acagggggtc ttgaaatgta tgtgccaggg tggcaagcca tgttccgctg
5281 gatgcggttc cacgaccttg gcctgtggac aggagatcgc aatctcctgc ccgaattcgt
5341 aaatgatgat ggcgtctaag gacgccccaa catcccctga tggcgccagt ggcgccggcc
5401 agctggtacc ggaggctaat acagctgagc aaatttcaat ggaccctgtt gcgggtgctt
5461 caacagcagt cgcgacagct gggcaagtta acatgattga cccatggatt ttcaataact
5521 tcgtccaggc acctcaagga gaattcacta tttcccctaa taataccccc ggtgatattt
5581 tgtttgattt acaactagga ccccacctta acccatttct agcccatctc tcacagatgt
5641 acaatggttg ggtcggcaat atgcgtgtgc gcatactgtt ggccgggaat gccttcacag
5701 ctggaaagat aatcatttgc tgtgtccccc ctggttttga tgccagaata ctcacaatag
5761 ctcaagcaac tctcttccca cacttaattg ctgatgtaag gacccttgag cctgtggagc
5821 ttcctttgga ggatgtgcgc aatgttctct tccacaacag tagccaaccg cagccaacaa
5881 tgcggttggt tgctatgttg tacactcccc tccgcactgg tggtggttcc ggaggcactg
5941 atgcctttgt ggtcgcgggt agggtgctta cgtgccccgc ccccgacttt agttttctgt
6001 ttctagtccc cccttccgtt gaacaaaaga ccagagtttt cagtgtcccc aacatacccc
6061 tgaaggatct ctcaaattcc cgtgtccctg tgccagtgca gggcatgttt atgtccccag
6121 atgttaatca gtcagtccag tttcagaatg gacgctgcca aattgatggt caactccaag
6181 gcaccactcc agtctcgctc agccaactct gcaagattag gggtaaaact tctagcaatg
6241 ctagggtgct taacttaagt gaggtggatg gcacaccctt catcccactt gaatcaccag
6301 cgccagttgg ttttcccgac ttgggaggtt gtgattggca tgtaaatttc actttccagg
6361 ctcaaaatca ggacccatct caaagtgtaa cctttgcaac taatgatgct agctttgtcc
6421 cctatctagg tagtatctct cctcacaatg ggggagattt tcatgcaggt gacatcatag
6481 gtagccttgg ttggatttca gccccgtctg ataattcaca acttaatgtt tggacaatac
6541 caaagtatgg atctagtctc ccagatgtca ctcatcttgc ccctgctgtg ttccccccag
6601 gctttgggga ggtgatcttg tacttctatt ctaccttccc aggttctgga caatccagcc
6661 aacttcaagt cccatgcttg ttgcctcagg agtttatcac ccacttctgt aacgaacagg
6721 ctcccatcgc tggggaggct gccctcctcc actacgtgga ccctgatacg gggcgaaatt
6781 tgggagaatt caaactttac cctgatgggt ttatgacctg tgtccccaat agtgttagta
6841 gtggccctca aacccttcct atcaatggag tctttgtctt tgtttcatgg gtatctagat
6901 tctatcaact caagcctgtg ggaacggcct cagcggctag aaggcttgga ttgcggcgca
6961 tataatggcc caagctgtca tcggtgccat agccgcatct gccgctggta gcatactagg
7021 ggcaggcata caggctggtg ctgaggctgg tctccaggct caacggtatc agcaggatct
7081 gcagttgcaa caaaattctt tcaagcatga taaggaaatg ttaggttacc aagttcaggc
7141 tagtaatgct ctcttagcta agaatcttaa cactagatat gctcttctgc aggcaggggg
7201 cctatctagc gctgatgctg ctcgggcagt ggctggtgct cctgtcaccc gtatagtgga
7261 ctggaatggc acgcgcattg cggcgcccac ttcaagcacc actacactca gatctggtgg
7321 ttttatggct gtccctatac cattgtcttc aaagaccaag caaccagtga tgtctgggca
7381 ggataatcca aattatgctg cttcttctat ctctagaact gcttcatggg tgcaatctca
7441 aaattctatg aggtctgttt ctccttttca cagtgacgct ttgagaaccg tttgggttac
7501 accacccggt tcatcatcaa cttcatctgt gcaatctagt ttctatggtg tttttaatac
7561 agatagattg cctctgttcg caaacagaag gtaataaaat ttttgtaata ggatgccagt
7621 gggcaccata ttcagatttg gttttaatta gattgttttt aattaaaatt tggc
//