Typing tool
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Typing tool
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Complete norovirus genomes
| MH413070 | GII.4 Hunter | |
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| GII.P4 Hunter |
ORF1: 3..5102
ORF2: 5083..6705
ORF3: 6705..7511
LOCUS MH413070 7558 bp RNA linear VRL 10-JUN-2018
DEFINITION Norovirus GII isolate 0859, complete genome.
ACCESSION MH413070
VERSION MH413070.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7558)
AUTHORS Chen,H. and Hu,Y.
TITLE Whole-genome sequences of two human norovirus GII.4 variants
isolated in the United States
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7558)
AUTHORS Chen,H. and Hu,Y.
TITLE Direct Submission
JOURNAL Submitted (30-MAY-2018) Center for Food Safety and Applied
Nutrition, Food and Drug Administration, 8301 Muirkirk Rd, Laurel,
MD 20708, USA
FEATURES Location/Qualifiers
source 1..7558
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="0859"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="08-May-2008"
/note="genotype: GII.4"
gene 3..5102
/gene="ORF1"
CDS 3..5102
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="AWQ36948.1"
/translation="MKMASNDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARP
KQPPPREIPQRPPRPPTPELVKNIPPPPPNGEDEIVISYSVKDGVSGLPDLSTVRQPE
ESNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LARVELTPLSLFWRPVYTPQYLISPDALKKLHGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCALSSLFTRPIKDIIGK
LRPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAIVRSIEDAVLDLEAIENNHMTILLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREV
AKRIAASLTGDQRVGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSSDFSHIKLTLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEFELQGPTLTTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVRTM
PELKQALKNISIKKCQIVHNGCTYTLESDGKGNVKVDRVQSASVQTNNELTGALHHLR
CARIRYYVRCVQEALYSIIQIAGAAFVTTRIVKRMNIQDLWSKPQVENTEETTGKDGC
PRPKDDEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVVTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGSAPKLSTKTKFWRSSTASLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFERHSRYTYHYDADYSRWD
STQQRAVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTNLSPDTIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLR
EYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGS
NHEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 3..992
/gene="ORF1"
/product="p48"
mat_peptide 993..2090
/gene="ORF1"
/product="NTPase"
mat_peptide 2091..2627
/gene="ORF1"
/product="p22"
mat_peptide 2628..3026
/gene="ORF1"
/product="VPg"
mat_peptide 3027..3569
/gene="ORF1"
/product="Pro"
mat_peptide 3570..5099
/gene="ORF1"
/product="RdRp"
gene 5083..6705
/gene="ORF2"
CDS 5083..6705
/gene="ORF2"
/codon_start=1
/product="VP1"
/protein_id="AWQ36949.1"
/translation="MKMASNDATPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHIAGTQNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGRIQGVL
TQTTRRDGSTRGHKATVSTGSVHFTPKLGSVQFSTDTSNDFETGQNTRFTPVGVVQDG
STTHQNEPQQWVLPDYSGRDSHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMNLD
CLLPQEWVQHFYQESAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGAGRRRAL"
gene 6705..7511
/gene="ORF3"
CDS 6705..7511
/gene="ORF3"
/codon_start=1
/product="VP2"
/protein_id="AWQ36950.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAVN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGASSGRTNLRATVPARGSSSTPS
NASTATSVYSNQTASTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 gaatgaagat ggcgtctaac gacgcttccg ctgccgctgt tgctaacagc aacaacgaca
61 ccgcaaaatc ttcaagtgac ggagtgcttt ctagcatggc tgtcactttt aaacgagccc
121 tcggggcgcg gcctaagcag cctcccccga gggaaatacc acaaagaccc ccacgaccac
181 ctactccaga actggtcaaa aatatccccc ctcccccgcc caacggagag gatgaaatag
241 tgatttctta tagtgtcaaa gatggtgttt ccggtttgcc tgatctttcc accgtcaggc
301 aaccggaaga atctaacacg gccttcagtg tccctccact caatcagagg gagaatagag
361 atgctaagga gccactgact ggaacaattc tggaaatgtg ggatggagaa atctaccatt
421 atggcctgta tgtggagcga ggtcttgtac taggtgtgca caaaccacca gctgccatta
481 gcctcgctag ggtcgaactg acaccactct ccttgttctg gagacctgtg tatactcccc
541 agtacctcat ctctccagac gctctcaaga aattacacgg agagacgttc ccctacacag
601 cctttgacaa caattgctat gccttttgtt gctgggtcct ggacctaaac gactcgtggc
661 tgagtaggag aatgatccag agaacaactg gcttcttcag gccctaccaa gattggaata
721 ggaaacccct ccccactatg gatgactcca agttaaagaa ggtagctaac atattcctgt
781 gtgctctgtc ttcgctattc accaggccca taaaagatat aatagggaag ctaaggcctc
841 ttaacatcct caacatcttg gcctcatgtg attggacttt tgcaggcata gtggagtcct
901 tgatactctt ggcagaactc tttggagttt tctggacacc cccagacgtg tctgcgatga
961 ttgccccttt actcggtgat tacgagctac aaggacctga ggaccttgca gtggagctcg
1021 tccctgtagt gatgggggga attggtttgg tgctaggatt caccaaagag aagattggaa
1081 aaatgttgtc atctgctgca tccaccttga gagcttgtaa agatcttggt gcatatgggc
1141 tagagatcct aaagttggtc atgaagtggt tcttcccgaa gaaagaggaa gcaaatgaac
1201 tggctatagt gagatccatc gaggatgcag tcctggatct cgaggcaatt gaaaacaacc
1261 atatgaccat cttgctcaaa gacaaagaca gtctggcaac ctacatgaga acccttgacc
1321 ttgaggagga gaaagccagg aaactctcaa ccaagtctgc ttcacctgac atcgtgggca
1381 caatcaacgc ccttctagcg agaatcgctg ctgcacgttc tctggtgcat cgagcgaagg
1441 aggaactttc cagcagacca agacctgtag tgttgatgat atcaggcaga ccaggaatag
1501 gaaagaccca ccttgctagg gaagtggcta agagaatcgc agcctccctt acaggagacc
1561 agcgtgtagg cctcgtccca cgcaatggcg tcgaccattg ggatgcgtac aagggggaga
1621 gggtcgtcct atgggacgac tatggaatga gcaaccccat ccacgatgcc ctcaggttgc
1681 aagaactcgc tgacacttgc cccctcaccc taaactgtga caggattgag aataaaggaa
1741 aggtctttga cagcgatgtc atcattatca ccactaatct ggctaaccca gcaccactgg
1801 actatgtcaa ctttgaagca tgctcgaggc gcatcgactt cctcgtgtat gcagaagctc
1861 ctgaggtcga aaaggcgaaa cgtgacttcc caggccaacc cgacatgtgg aagaacgcct
1921 tcagttctga tttctcacac ataaaactaa cattggctcc acagggtggc ttcgacaaga
1981 acgggaacac cccacacgga aagggcgtca tgaagactct caccactggc tcccttattg
2041 cccgggcatc agggctactc catgagaggc tagatgaatt tgaactacag ggcccaactc
2101 tcaccacctt caactttgat cgcaacaaag tgcttgcctt tagacaactt gctgctgaaa
2161 acaaatatgg gttgatggac acaatgaaag ttgggaggca gctcaaggat gtcagaacaa
2221 tgccagagct taaacaagca ctcaagaaca tctcaatcaa gaagtgccag atagtgcata
2281 atggttgcac ctacacactt gagtctgatg gcaagggcaa tgtgaaagtt gacagagttc
2341 aaagcgcctc cgtgcagacc aacaatgagc tgactggcgc cctgcaccat ctaaggtgcg
2401 ccagaataag atactatgtc aggtgtgtcc aggaggccct gtattccatc attcagattg
2461 ctggggctgc atttgtcacc acgcgcatcg tcaagcgcat gaacatacaa gacctatggt
2521 ccaagccaca agtggaaaac acagaggaga ctaccggcaa ggacgggtgt ccaagaccca
2581 aagatgatga ggagttcgtc atttcatccg acgacatcaa aactgagggt aagaaaggga
2641 agaacaagac tggccgcggc aagaagcaca cagccttctc aagcaaaggt ctcagtgatg
2701 aagagtacga tgagtacaag aggattagag aggaaaggaa tggcaagtac tccatagaag
2761 agtaccttca ggacagggac aaatactatg aggaggtggc cattgccagg gcgactgagg
2821 aggacttctg tgaggaggag gaggccaaga tccggcagag gatcttcagg ccaacaagga
2881 aacaacgcaa ggaggaaaga gcttctctcg gtttagttac aggttctgaa attaggaaaa
2941 gaaatccaga tgatttcaaa cccaaaggga aactgtgggc tgacgatgac agaagtgtgg
3001 actacaatga gaaactcagt tttgaagccc caccaagcat ctggtcgagg atagtcaact
3061 ttggttcagg ttggggattc tgggtctccc ccagtctgtt cataacatca acccacgtca
3121 taccccaggg cgcaaaggag ttctttggag tccccatcaa acaaattcag gtacataagt
3181 caggcgaatt ctgtcgcttg agattcccaa aaccaatcag gactgatgtg acgggcatga
3241 tcttagaaga aggtgcaccc gagggcaccg tggtcacact actcatcaaa aggtccactg
3301 gagaactcat gcccctagca gctaggatgg ggacccatgc aaccatgaaa atccaaggac
3361 gcactgttgg aggtcaaatg ggcatgcttc tgacaggatc caacgccaaa agcatggacc
3421 tgggtaccac accaggtgat tgtggctgtc cctacatcta caagagagga aatgactatg
3481 tggtcattgg agtccacacg gctgccgctc gtgggggaaa cactgtcata tgtgccaccc
3541 aggggagtga gggagaggct acacttgaag gtggtgacaa taaagggaca tactgtggtg
3601 caccaatcct aggcccaggg agtgccccaa aacttagcac caagaccaag ttttggagat
3661 cgtccacagc atcactccca cctggcacct atgaaccagc ctatcttggt ggcaaggacc
3721 ccagagtcaa gggtggccct tcactgcagc aagtcatgag ggatcagttg aagccattta
3781 cagagcccag gggcaagcca ccaaagccaa gtgtgttgga agctgccaag aaaaccatca
3841 tcaatgtcct tgagcaaaca attgatccac ctgagaaatg gtcattcgca caagcttgcg
3901 cgtcccttga caagaccact tccagtggcc atccgcatca catgcggaaa aacgactgct
3961 ggaacgggga gtccttcaca ggcaagctgg cagaccaggc ttccaaggcc aacctgatgt
4021 ttgaagaagg gaagaacatg accccagtct acacagctgc gcttaaggat gaattagtta
4081 aaactgacaa aatttatggt aagatcaaga agaggcttct ctggggctcg gatttggcga
4141 ccatgattcg gtgtgctcga gcattcggag gcctaatgga tgaactcaaa gcgcactgtg
4201 tcacacttcc cattagagtt ggtatgaata tgaatgagga tggccccatt atcttcgaga
4261 ggcattccag gtacacatac cactatgatg ctgattactc tcgatgggat tcaacacaac
4321 agagagccgt gttggcagca gctttagaaa tcatggttaa attttcccca gaaccacatt
4381 tggctcaggt agtcgcagaa gaccttcttt ctcctagcgt ggtggacgtg ggtgacttca
4441 caatatcaat caacgagggt cttccctctg gggtgccctg cacctcccaa tggaactcca
4501 tcgctcactg gcttctcact ctctgtgcgc tctctgaagt tacaaacttg tctcctgaca
4561 ccatacaggc taattccctc ttctcttttt atggtgatga tgaaattgtt agcacagaca
4621 taaaattgga cccagagaag ttgacagcaa agctcaggga atatgggtta aagccaaccc
4681 gccctgacaa aactgaagga ccccttgtca tctctgaaga cttgaatggc ctgactttcc
4741 tgcggagaac tgtgacccgc gacccagctg gttggtttgg aaaattggag cagagttcaa
4801 tactcaggca aatgtactgg actaggggtt ccaaccatga agacccatct gaaacaatga
4861 tcccacactc ccaaagaccc atacaattga tgtccctact gggggaggcc gcactccacg
4921 gcccagcatt ctacagcaaa atcagcaagt tagtcattgc agagctaaaa gaaggtggca
4981 tggattttta cgtgcccaga caagagccaa tgttcagatg gatgagattc tcagatctga
5041 gcacgtggga gggcgatcgc aatctggctc ccagttttgt gaatgaagat ggcgtcgaat
5101 gacgccaccc catctgatgg gtccacagcc aacctcgtcc cagaggtcaa caatgaggtt
5161 atggctttgg agcccgttgt tggtgccgcg attgcggcac ctgtagcggg ccaacaaaat
5221 gtaattgacc cctggattag aaataatttt gtacaagccc ctggtggaga gtttacagta
5281 tcccctagaa acgctccagg tgaaatatta tggagcgcgc ccttgggccc tgatttgaac
5341 ccctaccttt cccatttggc cagaatgtac aatggttatg caggtggttt tgaagtgcaa
5401 gtaatcctcg cggggaacgc gttcaccgcc gggaaaatca tatttgcagc agtcccacca
5461 aatttcccaa ctgaaggctt gagccccagc caggtcacta tgttccccca tataatagta
5521 gatgttaggc aactggaacc tgtgttgatc cccctgcctg atgttaggaa taatttctat
5581 cattacaatc aatcaaatga ccccaccatc aaattgatag caatgctgta tacaccactt
5641 agggctaaca atgctgggga cgatgtcttc acagtctctt gtcgagttct cacgagacca
5701 tcccccgatt ttgatttcat atttttggtg ccacccacag ttgagtcaag aactaaacca
5761 ttctctgtcc caatcttaac tgttgaggag atgaccaatt caaggttccc tattcctttg
5821 gaaaagttgt tcacgggtcc cagcagtgcc tttgttgttc aaccacaaaa tggcagatgc
5881 acgactgatg gcgtgctttt aggtactacc caactgtctc ctgtcaacat ctgcaccttc
5941 agaggggatg tcacccacat tgcaggtact caaaattaca caatgaatct ggcctcccaa
6001 aattggaaca attatgaccc aacagaagaa atcccagctc ctctgggaac cccagatttt
6061 gtaggaagga tccaaggcgt gctcacccaa accacaagga gggacggctc gacccgcggt
6121 cacaaagcca cagtaagcac tggaagtgtc cacttcaccc caaagctggg cagtgttcaa
6181 ttctctactg atacaagcaa tgactttgaa actggccaaa acacgagatt caccccagtc
6241 ggtgtcgtcc aggatggtag taccacccac caaaatgaac cccaacaatg ggtgctccca
6301 gactattcag gtagagatag ccacaatgta cacctagccc ctgccgtggc ccccactttt
6361 ccgggtgagc aacttctttt ctttaggtcc actatgcccg gatgcagcgg gtatcccaac
6421 atgaatttgg attgcctact cccccaggag tgggtgcagc acttctacca agagtcagcc
6481 ccagcacaat ctgatgtggc actgctgaga tttgtgaatc cagacacagg tagggttttg
6541 tttgagtgca agcttcataa atcaggctat gtaacagtgg ctcacactgg ccaacatgat
6601 ttggttatcc cccccaatgg ctattttaga tttgattcct gggtcaacca attctacaca
6661 cttgccccca tgggaaatgg agcggggcgt agacgtgcat tataatggct ggagctttct
6721 ttgctggatt ggcatctgat gtccttggct ctggacttgg ctctctaatc aatgctgggg
6781 ctggggccat caaccaaaaa gttgagtttg aaaataacag aaaattgcaa caagcttcct
6841 tccaatttag cagcaaccta caacaggctt cctttcaaca tgataaagag atgctccaag
6901 cacaaattga ggccaccaaa aagttgcaac aggaaatgat gaaagttaaa caggcaatgc
6961 tcctagaggg tgggttctct gagacagatg cagcccgtgg ggcagtcaac gcccccatga
7021 caaaggcttt ggactggagc ggaacaaggt actgggctcc cgatgctagg actacaacat
7081 acaatgcagg ccgcttttcc acccctcaac cctcgggggc atcgtcagga agaactaatc
7141 ttagggctac tgtccccgct cggggctcct ccagcacacc ctctaatgct tctactgcta
7201 cttctgtgta ctcaaatcaa actgcttcaa cgagacttgg ttctacagct ggttctggta
7261 ccagtgtctc gagcctcccg tcaactgcaa ggactaggag ctgggttgag gatcaaaaca
7321 ggaatttgtc acctttcatg aggggggccc acaacatatc gtttgtcacc ccaccatcta
7381 gtagatcctc tagccaaggc acagtctcaa ccgtgcctaa agaagttttg gactcctgga
7441 ctggcgcttt caacacgcgc aggcagcctc tcttcgctca cattcgtaag cgaggggagt
7501 cacgggtgta atgtgaaaag acagaaattg attatcattc ttttcttcag tgtctttt
//