Typing tool
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Typing tool
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Complete norovirus genomes
| MH413069 | GII.4 New Orleans | |
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| GII.P4 New Orleans |
ORF1: 1..5099
ORF2: 5080..6702
ORF3: 6702..7508
LOCUS MH413069 7554 bp RNA linear VRL 10-JUN-2018
DEFINITION Norovirus GII isolate 10149, partial genome.
ACCESSION MH413069
VERSION MH413069.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7554)
AUTHORS Chen,H. and Hu,Y.
TITLE Whole-genome sequences of two human norovirus GII.4 variants
isolated in the United States
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7554)
AUTHORS Chen,H. and Hu,Y.
TITLE Direct Submission
JOURNAL Submitted (30-MAY-2018) Center for Food Safety and Applied
Nutrition, Food and Drug Administration, 8301 Muirkirk Rd, Laurel,
MD 20708, USA
FEATURES Location/Qualifiers
source 1..7554
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="10149"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="03-Jan-2010"
/note="genotype: GII.4"
gene <1..5099
/gene="ORF1"
CDS <1..5099
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="AWQ36947.1"
/translation="KMASNDASAAAVANSNNDIAKSSSDGVLSSMAVTFKRALGARPK
QPPPREKPQRPPRPPTPELVKNIPPPPPNGEDEIVVSYSVKDGVSGLPDLSTVRQPEE
SNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAISL
AKVELAPLSLYWRPVYTPQYLISPDTLKKLSGETFPYTAFDNNCYAFCCWVLDLNDSW
LSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKIKKVANIFLCALSSLFTRPIKDIIGKI
RPLNILNILASCDWTFAGIVETLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDL
AVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPK
KEEANELAIVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTK
SASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREVA
KRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCP
LTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKA
KRDFPGQPDMWKNAFSSDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARAS
GLLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGKQLKDVRTMP
ELKQALKNVSIKKCQIVYSGCTYILESDGKGNVKVDRIQSAAVQINNELAGALHHLRS
ARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVENTEETTSKDGCP
KPKDDEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGK
YSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLVT
GSEIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSPS
LFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGT
VATLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDC
GCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGS
GSAPTLSTKTKFWRSSTVSLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPFTEPR
GKPPRPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHVRKNDCWN
GESFTGKLADQASKANLMFEEGKNMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDLA
TMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFERHSRYTYHYDADYSRWDS
TQQRAVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTNLSPDTIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLRE
YGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPN
HGDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..989
/gene="ORF1"
/product="p48"
mat_peptide 990..2087
/gene="ORF1"
/product="NTPase"
mat_peptide 2088..2624
/gene="ORF1"
/product="p22"
mat_peptide 2625..3023
/gene="ORF1"
/product="VPg"
mat_peptide 3024..3566
/gene="ORF1"
/product="Pro"
mat_peptide 3567..5096
/gene="ORF1"
/product="RdRp"
gene 5080..6702
/gene="ORF2"
CDS 5080..6702
/gene="ORF2"
/codon_start=1
/product="VP1"
/protein_id="AWQ36945.1"
/translation="MKMASNDANPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHIPGSRNYTMNLASQNWNSYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRTNGSTRGHKATVYTGSADFSPKLGRVQFATDTDNDFETNQNTKFTPVGVIQDG
STTPRNEPQQWVLPSYSGRNIHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
gene 6702..7508
/gene="ORF3"
CDS 6702..7508
/gene="ORF3"
/codon_start=1
/product="VP2"
/protein_id="AWQ36946.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMRVKQAMLLEGGFSETDAARGAIN
APMTKTLDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANLRATVPARGSPSMSS
NSSIATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 tgaagatggc gtctaacgac gcttccgctg ccgctgttgc taacagcaac aacgacatcg
61 caaaatcttc aagtgacgga gtgctttcta gcatggctgt cacttttaaa cgagccctcg
121 gggcgcggcc taaacagcct cccccgaggg aaaaaccaca aagaccccca cgaccaccta
181 ctccagaact ggtcaaaaat attccccctc ccccacccaa cggagaggat gaaatagtgg
241 tttcttatag tgtcaaagat ggtgtttccg gcttgcctga cctttccacc gtcaggcaac
301 cggaagaatc taacacggcc ttcagtgtcc ctccactcaa tcagagggag aatagagacg
361 ctaaggagcc acttactgga acaattctgg aaatgtggga cggggaaatc taccattatg
421 gtctgtatgt ggagcgaggt cttgtactag gtgtgcacaa accaccagct gccatcagcc
481 tcgctaaggt tgagctagca ccactctcct tgtactggag acctgtgtac actcctcagt
541 acctcatctc tccagacact ctcaagaaat tatccggaga aacgtttccc tacacagcct
601 ttgacaacaa ctgttatgcc ttttgttgct gggtcctgga cctaaatgac tcgtggctga
661 gcaggagaat gatccagaga acaactggtt tcttcaggcc ctaccaagac tggaatagga
721 aaccccttcc cactatggat gactccaaaa taaagaaggt agctaacata ttcctgtgtg
781 ctctgtcctc gctgttcact agacccataa aagatataat agggaagata aggcctctta
841 acatcctcaa catcttagcc tcatgtgatt ggacttttgc aggcatagtg gagaccctga
901 tactcttggc agaactcttt ggagttttct ggacaccccc agatgtgtct gcgatgattg
961 cccccttact tggtgactac gagctacaag gacctgagga ccttgcagtg gagctcgtcc
1021 ccgtggtgat ggggggaatt ggtttggtac taggattcac caaagagaag attgggaaaa
1081 tgttgtcatc tgctgcgtcc accctgagag cttgtaaaga ccttggtgca tatgggctag
1141 agatcctaaa gttggttatg aagtggttct tcccgaagaa ggaggaggca aatgagctgg
1201 ctatagtgag gtctatcgag gatgcagtcc tagacctcga ggcaattgaa aacaaccata
1261 tgaccacctt gctcaaagac aaagacagtc tggcaaccta tatgagaaca cttgaccttg
1321 aggaggagaa agccaggaaa ctctcaacca agtctgcctc acccgacatc gtgggcacaa
1381 tcaacgccct cctggcgaga atcgctgccg cacgttctct ggtgcatcga gcgaaggagg
1441 agctttccag cagaccaaga cctgtggtgt tgatgatatc aggcaggcca ggaataggga
1501 agacccacct cgctagggaa gtggctaaga gaatcgcagc ctcccttaca ggagaccagc
1561 gtgtgggcct catcccacgc aatggcgtcg accattggga tgcgtacaag ggggagaggg
1621 tcgtcctatg ggacgattat ggaatgagca accctattca cgatgccctc aggctgcaag
1681 aactcgctga cacttgcccc ctcactctaa actgtgacag gattgaaaat aaaggaaagg
1741 tctttgacag cgatgtcatc attatcacca ctaatctggc caacccagca ccactggact
1801 atgtcaactt tgaagcatgc tcgaggcgca tcgacttcct cgtgtatgca gaagcccctg
1861 aagtcgaaaa ggcgaagcgt gacttcccag gccaacctga catgtggaag aacgctttca
1921 gttctgattt ctcacacata aaactagcac tggccccaca gggtggtttc gacaagaacg
1981 ggaacacccc acacggaaag ggcgtcatga agactctcac cactggctcc cttattgccc
2041 gggcatcagg gctactccat gagaggttag atgaatttga actacagggc ccagctctca
2101 ccaccttcaa ttttgatcgc aataaagtgc ttgcctttag acagcttgct gctgaaaata
2161 aatatggatt gatggacaca atgagggtcg ggaaacagct caaggatgtc agaaccatgc
2221 cagaactcaa acaagcactc aagaatgttt caatcaagaa gtgccaaata gtgtatagtg
2281 gttgtaccta catacttgag tctgatggca agggcaatgt gaaagttgac agaatccaaa
2341 gcgccgccgt gcagatcaac aatgagctgg ctggtgccct gcaccatttg aggagcgcca
2401 gaatcagata ctatgtcaag tgtgtccagg aggccctgta ttccatcatt caaattgccg
2461 gggctgcatt tgtcaccacg cgcattgcca agcgcatgaa catacaaaac ctatggtcca
2521 agccacaagt ggaaaacaca gaggagacta ccagcaagga cgggtgccca aaacctaagg
2581 atgatgagga gtttgtcatt tcatccgacg atatcaaaac tgagggcaag aaggggaaga
2641 acaagactgg ccgcggcaag aagcacacag cattttcaag caaaggcctc agtgatgaag
2701 agtacgatga gtacaagagg attagagaag aaaggaatgg caagtactcc atagaagagt
2761 accttcagga cagggacaaa tactatgagg aggtggccat tgccagggcg actgaggaag
2821 acttctgtga agaggaggag gccaagatcc ggcaaaggat ctttagacca acaaggaaac
2881 aacgcaagga ggaaagagcc tctctcggtc tggtcacagg ctctgaaatt aggaaaagaa
2941 acccagatga cttcaaaccc aaggggaaat tgtgggctga cgatgatagg agtgtggact
3001 acaatgagaa actcagcttt gaggccccac caagcatctg gtcgagaata gtcaactttg
3061 gttcaggctg gggattctgg gtctccccca gtctgttcat aacatcaacc catgtcatac
3121 cccagggcgc aaaggagttc tttggagtcc ccatcaaaca aatacaggta cacaagtcag
3181 gcgagttctg tcgcttgaga ttcccaaaac caatcaggac tgatgtgacg ggcatgatct
3241 tagaagaagg cgcacctgag ggcaccgtgg ccacactact catcaaaagg tccactgggg
3301 aactcatgcc cctagcagct aggatgggga cccatgcgac catgaagatc caagggcgca
3361 ctgttggagg ccagatgggc atgcttctga caggatccaa cgccaagagc atggacctgg
3421 gtactacacc aggtgattgt ggctgcccct atatctacaa gagaggtaat gactatgtgg
3481 tcattggagt ccacacggct gccgcacgtg ggggaaacac tgtcatatgt gccacccagg
3541 ggagtgaggg agaggctaca cttgaaggtg gtgacaacaa ggggacatac tgtggtgcac
3601 caatcctagg ctcagggagt gccccaacac ttagcaccaa aaccaaattc tggagatcgt
3661 ccacagtatc actcccacct ggcacctatg aaccagccta tcttggtggc aaggacccta
3721 gagtcaaggg tggcccttca ctgcagcaag tcatgaggga acagttgaag ccattcacag
3781 agccaagggg caagccacca agaccaagtg tattagaagc tgccaagaag accatcatca
3841 atgtccttga gcaaacaatt gatccacctg agaaatggtc gttcgcacaa gcttgcgcgt
3901 cccttgacaa gaccacttcc agtggtcatc cgcaccacgt gcggaaaaac gactgctgga
3961 acggggagtc cttcacaggc aagctagcag accaggcttc caaggccaac ctgatgtttg
4021 aagaagggaa gaacatgacc ccagtctaca cagctgcgct caaggatgag ttagttaaaa
4081 ctgacaaaat ttatggtaag atcaagaaga gacttctctg gggctcggac ttggcgacca
4141 tgatccggtg tgctcgagca ttcggaggtc tgatggatga gctcaaagca cactgtgtca
4201 cgcttcccat tagagttggc atgaatatga atgaggatgg ccccatcatc ttcgagaggc
4261 attccaggta cacatatcac tatgatgctg attactctcg atgggattca acacaacaga
4321 gggccgtgtt ggcagcagct ctagaaatca tggttaaatt ctccccagaa ccacatttgg
4381 ctcaggtagt cgcggaagac cttctttctc ctagcgtggt ggacgtgggc gacttcacaa
4441 tatcaatcaa cgagggtctt ccctctgggg tgccctgcac ctcccaatgg aactccatcg
4501 cccactggct tctcactctc tgtgcgctct ctgaagtcac aaacctgtcc cctgatacca
4561 tacaggctaa ctccctcttc tctttttatg gtgatgatga aattgttagc acagacataa
4621 aattggaccc agagaaattg acagcaaagc tcagagagta tgggttaaaa ccaacccgcc
4681 ctgacaaaac tgaaggaccc cttgtcatct ctgaagatct gaatggccta actttcctgc
4741 ggagaactgt gacccgcgac ccagctggtt ggtttggaaa actggagcag agttcaatac
4801 tcaggcaaat gtactggact aggggtccca accatggaga cccatctgaa acaatgattc
4861 cgcactccca aagacccata caattgatgt ccctactggg ggaggccgct ctccacggcc
4921 cagcctttta cagcaaaatc agcaaattgg tcattgcaga gctaaaagaa ggtggcatgg
4981 atttttacgt gcccagacaa gagccaatgt tcagatggat gagattctca gatctgagca
5041 cgtgggaggg cgatcgcaat ctggctccca gttttgtgaa tgaagatggc gtcgaatgac
5101 gccaacccat ctgatgggtc cacagccaac ctcgtcccag aggtcaacaa tgaggttatg
5161 gctttggagc ccgtagttgg tgccgccatt gcggcacctg tagcgggcca acaaaatgta
5221 attgacccct ggattagaaa caactttgta caagcccctg gtggagagtt tacagtatcc
5281 cctagaaacg ctccaggtga aatactatgg agcgcgccat taggccctga tctgaatccc
5341 tacctttccc atttggccag aatgtacaat ggttatgcag gtggttttga agtgcaggta
5401 atcctcgcgg ggaacgcgtt caccgccggg aagatcatat ttgcagcagt cccaccaaat
5461 ttcccaactg aaggtttgag ccccagccag gtcactatgt tcccccacat aatagtagat
5521 gttaggcaat tggaacctgt gttgatcccc ttacccgatg ttaggaataa tttctaccat
5581 tataatcaat caaatgaccc cactatcaaa ttgatagcaa tgttgtatac accacttagg
5641 gctaataatg ccggggacga tgtcttcaca gtttcttgtc gagttctcac gagaccatcc
5701 cccgattttg atttcatatt tttggtgcca cccacagttg aatcaagaac taaaccattc
5761 tctgtcccag ttttaactgt tgaggagatg accaattcaa ggttccccat tcctttggaa
5821 aagttgttca cgggccccag tagtgccttt gttgttcaac cacaaaatgg caggtgcacg
5881 actgatggcg tgctcctagg tactacccaa ctgtcccctg tcaacatctg caccttcaga
5941 ggtgatgtca cccatattcc aggcagtcgt aactacacaa tgaatttggc ctcccaaaat
6001 tggaacagtt acgatccaac agaagaaatc ccagcccctc taggaactcc agatttcgtg
6061 gggaagattc aaggtgtgct cacccaaacc acaaggacaa atggctcgac ccgcggccac
6121 aaagctacag tgtacactgg gagcgccgac ttctctccaa aactgggtag agttcaattt
6181 gccactgaca cagacaatga ttttgaaact aaccaaaaca caaagttcac cccagtcggt
6241 gttatccagg atggtagcac caccccccga aatgaacccc aacaatgggt gctcccaagt
6301 tactcaggca gaaatattca taatgtgcac ctggcccccg ctgtagcccc cactttcccg
6361 ggcgagcagc tcctcttctt cagatctact atgcccgggt gcagcgggta ccccaacatg
6421 gatttggact gtctgctccc ccaggaatgg gtgcagtatt tctaccaaga ggcagcccca
6481 gcacaatctg atgtggctct tttaagattt gtgaatccag acacaggtag ggttttgttt
6541 gagtgtaagc ttcataaatc aggctatgtt acagtggctc acactggcca acatgatttg
6601 gttatccccc ccaatggtta ttttagattt gattcctggg tcaaccagtt ctacacactt
6661 gcccccatgg gaaatgggac ggggcgtaga cgtgcattat aatggctgga gctttctttg
6721 ctgggttggc atctgacgtc cttggctctg gacttggttc cctaatcaat gctggggctg
6781 gggccatcaa ccaaaaagtt gaatttgaaa ataacagaaa attgcaacaa gcttccttcc
6841 aatttagtag caatctacaa caggcttcct ttcaacatga caaagagatg ctccaagcac
6901 aaattgaggc caccaaaaag ttgcaacagg aaatgatgag agttaaacaa gcaatgctcc
6961 tagagggtgg attctctgag acagatgcag cccgtggggc aatcaacgcc cccatgacaa
7021 aaactttgga ctggagcggg acaaggtact gggctcccga tgctaggact acaacatata
7081 atgcaggccg cttttccacc ccccaaccct cgggggcatt accaggaaga gctaatctta
7141 gggctaccgt ccccgcccgg ggttccccca gtatgtcttc taactcttct attgctactt
7201 ctgtgtattc aaatcaaacc acctcaacga gacttggttc tacagctggt tctggtacca
7261 gtgtctcgag cctcccgtca actgcaagga ctaggagttg ggttgaggat caaaatagga
7321 atttgtcacc tttcatgagg ggggcccaca acatctcgtt tgtcacccca ccatctagca
7381 gatcctctag ccaaggcaca gtctcaaccg tgcccaaaga agttttggac tcctggactg
7441 gcgctttcaa cacgcgcagg cagcctctct tcgctcacat tcgcaagcga ggggagtcac
7501 gggtgtaatg tgaaaagaca aaattgatta tctttctttt ctttagtgtc tttt
//