Typing tool
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Typing tool
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Complete norovirus genomes
| MH218734 | GII.2 | |
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| GII.P2 |
ORF1: 5..5104
ORF2: 5085..6713
ORF3: 6713..7492
LOCUS MH218734 7536 bp RNA linear VRL 11-JUN-2018
DEFINITION Norovirus GII isolate NORO_95_25_01_2015, complete genome.
ACCESSION MH218734
VERSION MH218734.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7536)
AUTHORS Brown,J.R., Roy,S., Shah,D., Williams,C.A., Williams,R., Dunn,H.,
Hartley,J., Harris,K. and Breuer,J.
TITLE Norovirus transmission dynamics in a paediatric hospital using full
genome sequences
JOURNAL Clin. Infect. Dis. (2018) In press
PUBMED 29800111
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7536)
AUTHORS Brown,J.R., Roy,S., Shah,D., Williams,C.A., Williams,R., Dunn,H.,
Hartley,J., Harris,K. and Breuer,J.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2018) Division of Infection and Immunity,
University College London, 90 Gower St, London, London WC1E 6BT,
United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 10.1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7536
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="NORO_95_25_01_2015"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="United Kingdom"
/collection_date="25-Jan-2015"
/note="genotype: GII.P2_GII.2"
gene 5..5104
/gene="ORF1"
CDS 5..5104
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="AWR17860.1"
/translation="MKMASNDASAAAAVNSNNDNTKSSSDGMLNNMAVTLKRALGARP
KQPAPREKPPRPPRPPTPELIKRIPPPPPNDGDEPTVMFSTAGGVSGLPELTTVGQPP
EANTAFSVPPLSQRENRDAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAIS
IAKVELTPLSLYWRPVYTPQYLISPDTLRKLHGELFPYTAFENNCYAFCCWVLDLNDS
WLSRRMISRTTGFFRPYQEWNRKPLPTMDDSKLKKVANIVLCALSSLFTRPIKDIIGK
LKPLNILNILASCDWTFAGIVESLILLAELFDVFWTPPDVSAMIAPLLGDYELQGPED
IAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKDEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKNSLAAYMKTLDMEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGKPGIGKTHLAREL
AKKIASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLVNPAPLDYVNFEACSRRIDFLVYADAPEVEK
AKRDFPGQPDMWKDAYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTASSLVARA
SGLLHERLDEYELQGPPLSTFNFDRNKIAAFRQLAAENKYGLVDTMRVGNQLRNVTTM
DELKKAIKNIMIRKCQIVYGGNTYTLESDGKGKVVVERVQSASVQINNEIAGAVHHLR
CARIRYYVKCVQEAIYSLLQIAGTVFVTSRIVSRMNIQNLWSRPLSEDADEATIKEGC
PKPRDEEEFIVSSDDIKPEGKKGKNKSGRGKKHTAFSSKGLSDEEYEEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERANLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNERISFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGITEAFGVPIRQVQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEG
TVATILIKRTTGELMPLAARMGTHATMRIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGNAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPQKWTYAQACASLDKTTSSGYPHHVRKNEHW
NGESFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKVYGRIKKRLLWGSDL
ATMVRCARSFGGLMDELKAHCVTLPIRVGMNMNEDGPIVFEKHSRYRYHYDADYSRWD
STQQRAVLAAAMEIMVKFSAEPQLAQIVAEDLLSPSVVDVGDFKVSINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIVQANSLFSFYGDDEVVSTDIKLDPEKLTGKLR
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTKGP
NHEDPFESMIPHSQRPIQLMSLLGEAALHEPSFYSKISKLVISELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSLVNEDGVE"
mat_peptide 5..994
/gene="ORF1"
/product="p48"
mat_peptide 995..2092
/gene="ORF1"
/product="NTPase"
mat_peptide 2093..2629
/gene="ORF1"
/product="p22"
mat_peptide 2630..3028
/gene="ORF1"
/product="VPg"
mat_peptide 3029..3571
/gene="ORF1"
/product="Pro"
mat_peptide 3572..5101
/gene="ORF1"
/product="RdRp"
gene 5085..6713
/gene="ORF2"
CDS 5085..6713
/gene="ORF2"
/codon_start=1
/product="VP1"
/protein_id="AWR17861.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6713..7492
/gene="ORF3"
CDS 6713..7492
/gene="ORF3"
/codon_start=1
/product="VP2"
/protein_id="AWR17862.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGILTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPSSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLITTT
GSSHGTASSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc tgctgccgct gctgtcaaca gcaacaacga
61 caacacaaaa tcttcaagtg acggaatgct taataacatg gccgtcaccc ttaaacgagc
121 ccttggggcc cggcccaaac agccagcccc gagggaaaaa cccccaagac cccctagacc
181 accaacacca gaactaatca aaagaatccc ccccccacca cctaatgatg gggacgaacc
241 aaccgtgatg tttagcactg caggtggtgt gtctggccta cctgagctca caacagtcgg
301 tcaaccacct gaagctaaca ctgcctttag tgtgcccccc cttagccaaa gggaaaacag
361 ggacgctaag gaaccgttaa ctggggctat tctggaaatg tgggatgggg agatttatca
421 ttatggactg tatgtggaaa aagggcttgt gctaggcgtg cacaagccgc cggctgccat
481 cagcatagcc aaagtggaat tgacacctct ctcactgtat tggaggcctg tgtacacgcc
541 tcagtacctc atatctcctg acaccttgag gaaactccac ggtgagttat ttccctatac
601 agcctttgaa aacaactgtt atgccttctg ctgttgggtt ttggacctca acgattcatg
661 gctaagcaga aggatgatta gtaggactac tggcttcttc aggccctacc aagagtggaa
721 caggaaacct ctcccaacta tggatgactc aaaattgaag aaggtcgcaa acatcgttct
781 gtgtgcatta tcatcattgt tcactaggcc cattaaggat ataattggca aacttaaacc
841 ccttaacatc ctaaacattc tggcctcatg cgattggacc ttcgctggca tagtagaatc
901 actaatcctc ttggctgaac tctttgatgt gttctggaca cccccagatg tgtctgcaat
961 gatcgcaccc ctcctcggcg actatgagct acaaggtccc gaagacatcg ctgtggagct
1021 cgtgcccgtt gtgatgggtg ggataggtct ggtgttggga ttcaccaaag agaaaatagg
1081 caagatgctc tcctctgcag cgtcaactct gagggcgtgc aaagatcttg gagcctatgg
1141 attggagata ctgaaactag tcatgaaatg gtttttccca aagaaggatg aggccaacga
1201 actggctatg gttagagcca ttgaagacgc tgtgttagac ctggaggcta ttgaaaacaa
1261 ccatatgacc actctattga aggacaagaa cagccttgca gcatacatga agaccctgga
1321 catggaagag gaaaaagcta ggaagctatc caccaaatca gcctcccctg acattgtggg
1381 cactataaac gccctgctgg ctaggatcgc tgccgcgcgt tccctagttc atagggccaa
1441 ggaggagctc tccagcaggc caagaccggt cgttttgatg atctctggca agccagggat
1501 aggaaagacc cacttggcca gagaactggc aaagaaaatt gcctcaacac tcacaggaga
1561 ccaaagggtt ggtcttatcc cacggaatgg agttgaccat tgggacgcct acaaaggtga
1621 gagagtggtg ctctgggatg actatgggat gagcaacccc atccacgatg cgctgaggct
1681 gcaggaattg gcagacacat gtccattaac tctaaattgt gacaggattg aaaacaaggg
1741 gaaagtcttc gacagtgacg cgatcataat caccaccaat ttggtcaacc ccgcgccgct
1801 ggattatgtc aactttgagg cctgctccag acgtatagac ttccttgtgt atgctgatgc
1861 cccagaagtc gagaaagcaa agcgggactt tcccggtcaa ccggacatgt ggaaggacgc
1921 ctatcgctct gacttctcac acattaaact acaacttgca ccacaaggtg ggtttgacaa
1981 aaatggcaac accccacatg gtaaaggagt gatgaagact ctcactgcca gctcactggt
2041 cgcacgtgcc tctggtctct tacacgagag attagatgag tacgagttgc aaggtccgcc
2101 cctctcaact ttcaactttg accgtaacaa aattgcagca ttcagacaac tcgccgctga
2161 aaacaagtac ggtctggtag acacgatgag ggtgggcaac cagctcagaa atgtcacgac
2221 catggatgaa ctcaagaagg ctatcaagaa catcatgatc agaaagtgcc agatagtcta
2281 tggtggcaac acttacacgc ttgagtctga cggtaagggc aaggttgtag ttgagagggt
2341 gcagagcgcc agcgtgcaaa tcaacaatga gatcgctggt gcagtacacc atcttagatg
2401 tgccagaata aggtattatg tcaagtgtgt ccaagaggcc atatactcac tcctccagat
2461 tgccggcacg gtgtttgtca cttcacgcat cgtaagccgc atgaacatcc aaaatctgtg
2521 gtctaggcca ctatctgaag atgcagatga ggccaccata aaagaggggt gccctaaacc
2581 tagggatgaa gaagaattta tcgtctcctc agatgatatc aagccagagg gtaagaaagg
2641 taaaaacaag agtggccggg gcaagaaaca cacggcattc tcaagtaagg ggctcagtga
2701 tgaggagtac gaagagtaca aaagaatcag agaggagaga aatggcaagt actccataga
2761 ggaataccta caggacagag acaagtacta tgaagaggtg gccattgcca gggcaactga
2821 agaagacttc tgtgaagaag aagaggttaa gattcgtcag aggatcttca ggccaacaag
2881 aaagcaacgc aaggaagaaa gagccaacct tggcctcgtt accgggtctg agatcaggaa
2941 gagaaaccca gatgacttca aaccaaaagg aaagctgtgg gccgacgacg acaggagcgt
3001 cgactacaat gaaagaatca gctttgaggc cccaccaagc atttggtcta gaattgtcaa
3061 ctttggttct ggatgggggt tctgggtgtc acctagcctc ttcataacat caacacacgt
3121 catacctcaa ggcataactg aggcctttgg tgtacccata aggcaggtgc aaatacacaa
3181 gtcgggcgag ttctgtcgcc tgagattccc aaaacccatc agaacagatg tgtcaggcat
3241 gatactggag gagggagcgc ctgaaggtac tgttgccacc atactcatca aaagaaccac
3301 tggagagctg atgcctctag cagcaaggat gggcacccac gcgaccatga ggatacaagg
3361 gcgcacagtg ggcggccaga tgggaatgtt gctcactggg tccaatgcaa agagcatgga
3421 tcttggcacc acgcccggtg actgtgggtg tccctacatt tacaaaaggg gcaatgatta
3481 catagtcatt ggagttcaca cagcagccgc tcgtggcgga aacactgtta tctgcgccac
3541 acaaggtagt gagggtgagg ctactctcga gggtggtgac aataaaggaa catattgtgg
3601 ggcaccaatc ttaggccccg gaaatgcccc aaaactgagc actaaaacca agttctggag
3661 gtcctctaca acaccactcc cacccggcac gtacgagccg gcatatctgg gaggaaaaga
3721 cccccgagtc aaaggtgggc catctctgca acaagtcatg cgagaccaac tgaagccatt
3781 caccgaaccc cgtggcaagc caccaaaacc aagtgtcctt gaagctgcta aaaagacaat
3841 tatcaatgtg ttagagcaaa caatagaccc tccacagaag tggacgtacg cgcaagcgtg
3901 cgcgtctctt gacaaaacca catctagtgg gtacccccac cacgtgcgca aaaacgagca
3961 ctggaatggg gaatctttca caggaaaatt ggctgatcag gcttcgaagg caaacctaat
4021 gtttgaagag gggaaacaca tgaccccagt ttatacagct gcccttaagg acgagttggt
4081 caaaactgag aaagtgtatg ggaggataaa gaagaggttg ctctggggtt ctgacttggc
4141 caccatggtg aggtgtgcgc gctcctttgg cggtttgatg gacgaactca aggcccactg
4201 tgtgacactc ccgataaggg ttggcatgaa tatgaatgaa gatggaccaa tagtctttga
4261 gaaacattcc agatataggt atcactatga tgcagactac tccaggtggg attcaacaca
4321 gcagagagcc gttctggccg cggccatgga gattatggtt aaattctcag cagaaccaca
4381 attagcccaa atagttgcag aggatctgtt gtcgcccagt gttgttgacg tgggcgactt
4441 caaagtttcc atcaacgaag gattaccatc gggtgtccct tgcacctctc aatggaactc
4501 catcgcacac tggctcctca ccttgtgtgc cctttctgaa gttacagacc tctctcctga
4561 cattgtgcaa gccaactccc tcttctcctt ctatggtgat gatgaagttg tgagcacaga
4621 tatcaaatta gacccagaaa agttgacggg gaagttgagg gaatatggtc tcaaacccac
4681 ccgtcctgac aaaactgagg gccccttgat tattagtgag gatctgaatg gcctgacctt
4741 cctgaggaga accgttaccc gcgaccctgc aggatggttt ggcaaactgg accaaagctc
4801 catacttagg caattgtact ggaccaaagg ccctaaccat gaagacccct ttgagtcaat
4861 gattccacat tcccagagac ccatacaact catgtcactc ttgggtgaag cagcactgca
4921 tgaaccatca ttttacagca agatcagcaa gcttgtgata tccgagttga aagaaggtgg
4981 aatggatttt tacgtgccca ggcaagaacc tatgtttagg tggatgagat tctcggattt
5041 gagcacgtgg gagggcgatc gcaatcttgc tcccagtctc gtgaatgaag atggcgtcga
5101 atgacgccgc tccatctact gatggtgcag ccggcctcgt gccagaaagt aacaatgagg
5161 tcatggctct tgaacccgtg gctggtgccg ccttggcagc cccggtcacc ggtcaaacaa
5221 atattataga cccttggatt agagcaaatt ttgtccaggc ccccaatggt gaatttacag
5281 tctctccccg aaatgcccct ggtgaagtgc tactgaatct agagttgggt ccagaattaa
5341 atccttatct ggcacattta gcaagaatgt acaatgggta tgccggtggg atggaggtgc
5401 aggtcatgtt ggctgggaac gcgttcacag ccggcaagtt ggtcttcgct gccgtgccac
5461 ctcacttccc ggttgaaaat cttagcccac agcaaatcac catgttccct catgtgatca
5521 tagatgtgag aaccttggaa cctgttttat taccactccc tgatgttagg aataatttct
5581 tccattataa ccagaaagat gatcccaaga tgagaattgt ggctatgctt tatacccccc
5641 ttaggtctaa tggttcaggt gatgatgtgt ttacagtctc ctgcagagtg ttgactagac
5701 cttcccctga ttttgatttt acatacctgg tgccaccaac agtggagtct aaaacaaaac
5761 cattcaccct cccaatcctc acacttgggg aactttccaa ttctaggttc ccagtgtcca
5821 tagaccagat gtacaccagc cctaatgaag ttatatcagt gcagtgtcaa aatggtaggt
5881 gtacattgga cggggagctc caagggacaa cacaactcca agtcagtggc atttgtgctt
5941 tcaaaggaga agtgaccgcc cacttgcatg acaatgatca cctatataat gtcaccatca
6001 caaacttgaa tgggtcccct tttgatccct ccgaggatat ccctgcccct ctgggtgtgc
6061 ctgatttcca gggaagggtc tttggtatca tctcccaaag agacaaacac aatagtcccg
6121 ggcataatga accagcaaac aggggacacg acgctgtggt ccctacttac acagcacagt
6181 acactccaaa actgggacaa attcaaattg gcacatggca gactgacgac cttacagtca
6241 accaaccagt caaattcacc ccggttggac tcaatgacac tgaacatttt aaccaatggg
6301 tggtccctag gtatgctggt gccctaaatc tcaatacaaa ccttgcccct tctgttgctc
6361 cagtatttcc aggagagcgc ctgctcttct tcagatcata cattcccctc aagggtggtt
6421 atggaaaccc agccatcgat tgcctactac cacaagagtg ggtgcaacac ttctatcagg
6481 aagcagcccc ttcaatgagt gaggtggccc ttgtcagata catcaacccg gatactggtc
6541 gggcactgtt tgaggccaag cttcacagag ctggtttcat gacagtctcg agcaacacca
6601 gtgccccggt ggttgtgcct gccaacggat acttcaggtt tgattcttgg gtgaatcaat
6661 tctattctct cgcccccatg ggaactggga atgggcgtag aagggttcaa taatggctgg
6721 agcttttgta gctggtcttg caggggacgt gctcagcaat gggctcagtt cattaatcaa
6781 tgcaggtgct aatgcaataa atcagagggc agaatttgat tttaatcaga aattgcagca
6841 aaattctttt aatcatgaca aggagatgtt gcaggctcag attcaggcaa ctaagcagct
6901 gcaggcagac atgatggcta ttaaacaagg gatcttgacc gctggcggct tttcccctgc
6961 tgatgcagcc agaggtgctg tgaacgcgcc catgacacag gcgctggatt ggaatggcac
7021 aagatattgg gcaccaagct ccatgaggac cacatcttat tctggaaaat tcacatcaac
7081 cgccccagtg aggcaggccg acttccagca cacccaaagc cggccttcga gtggctcttc
7141 tgtgtcttcc tttgccactc agtcttcaag accaactctg atcacaacca ctggttcctc
7201 acatggcaca gcctcatcaa attcaactcg cagcacaagc ctctcccaat caacggtctc
7261 cagagctaca tctaggactg gtgagtgggt tagagatcaa aatagaaatt tggaacctta
7321 catgcatggt gccttacaga cagcctttgt caccccgcct tccagcaggg cgtctgacgg
7381 gacagtctca accgtcccga aaggtgtttt ggactcctgg acacctgcgt ttaacacccg
7441 caggcagccg ctttttgcac acctccgtaa gaggggggag tcacaagctt agtgaaaagg
7501 tgaaaatata tttaggatga attgatttta cctttt
//