Typing tool
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Typing tool
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Complete norovirus genomes
| MH218719 | GII.6 | |
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| GII.P7 |
ORF1: 5..5098
ORF2: 5079..6722
ORF3: 6722..7498
LOCUS MH218719 7550 bp RNA linear VRL 11-JUN-2018
DEFINITION Norovirus GII isolate NORO_68-7_18_03_2015, complete genome.
ACCESSION MH218719
VERSION MH218719.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7550)
AUTHORS Brown,J.R., Roy,S., Shah,D., Williams,C.A., Williams,R., Dunn,H.,
Hartley,J., Harris,K. and Breuer,J.
TITLE Norovirus transmission dynamics in a paediatric hospital using full
genome sequences
JOURNAL Clin. Infect. Dis. (2018) In press
PUBMED 29800111
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7550)
AUTHORS Brown,J.R., Roy,S., Shah,D., Williams,C.A., Williams,R., Dunn,H.,
Hartley,J., Harris,K. and Breuer,J.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2018) Division of Infection and Immunity,
University College London, 90 Gower St, London, London WC1E 6BT,
United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 10.1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7550
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="NORO_68-7_18_03_2015"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="United Kingdom"
/collection_date="18-Mar-2015"
/note="genotype: GII.P7_GII.6"
gene 5..5098
/gene="ORF1"
CDS 5..5098
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="AWR17817.1"
/translation="MKMASNDATTAFGSQNSVNDSINTAPSNKEEVGAFSNIKVGFKK
MLGAVPKGTKAPSSDQHCPSFKVGTKTLTVPPEPPNGEDTVQFDAKSETVRGLPDLTT
VQNEHENTPYTVPPLSEREHRPATEPLPGTILEMWDGEFYHYSVYVSGGKALGVHKPP
AAISLATIELTPISLYWRPVYTPNYLVCPDTLKGLAGEKFPYTAFSNNCYNFCCWVLE
LNDTWLSRRSISRTTGFFKPHQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKD
LLGKLKPLNLLHLLASCDWTFAGIVETVILMAELFGIFWTPPDVSSFIASLIGDFELQ
GPEDLAVELVPVVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMK
WFFPKKEEKAEMETLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKAR
KLSTKSSSPDIVGTINAILARIAAARSLLHKAKEEMFSRTRPVVVMISGRPGIGKTHM
ARHLAKSIANTMSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQEL
ADTCPVTLNCDRIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESP
EIEKVKRDFPGQPDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSL
TARVAGLVHERRDEFQLQGNNLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGTALKS
VKTLEDLKVALRDVKFNECEIIYRNSKYRVSSNGKGSVSVDKVEDQTSQTANEVGAAL
LRLRQARARYYVSCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTETQETSESEK
EVAQGRWEIEPRDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKY
SIEEYLQDRDRYYEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTG
SDIRKRRPDDFQPKGNPWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNL
LITTTHVLPKGINELFGVEIKQIQVHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTV
CSILVKRPTGEMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCG
CPYIYKRGNDIVVAGVHTAAARGGNTVICATQGQDGEAVLEGNENLGTYCGAPILGPG
KAPKLSTKTKFWRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRG
KPPRPAVLEEAKKTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHVRKNDHWNG
ESFTGPLADQASKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGT
MVRCARAFGGLMDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDST
QQRSILSAAMEVMVRFSAEPELAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQ
WNSIAHWILTLSAMAEVSGLSPDVIQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREY
GLVPTRPDKTEGPLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNH
ENPYESMVPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAM
FRWMRFSDLSTWEGDRNLAPEGVNEDGVE"
gene 5079..6722
/gene="ORF2"
CDS 5079..6722
/gene="ORF2"
/codon_start=1
/product="VP1"
/protein_id="AWR17815.1"
/translation="MKMASNDAAPSNDGAANLVPEATNEVMALEPVVGASIAAPVVGQ
QNIIDPWIRENFVQAPQGEFTVSPRNSPGEMLLNLELGPELNPYLSHLSRMYNGYAGG
MQVQVVLAGNAFTAGKIIFAAVPPHFPVENISAAQITMCPHVIVDVRQLEPVLLPLPD
IRNRFFHYNQENTPRMRLVAMLYTPLRANSGEDVFTVSCRVLTRPAPDFEFTFLVPPT
VESKTKPFTLPILTLGELSNSRFPAPIDMLYTDPNEAIVVQPQNGRCTLDGTLQGTTQ
LVPTQICSFRGTLISQTSRSADSTDSAPRVRNHPLHVQLKNLDGTPYDPTDEVPAVLG
AIDFKGTVFGVASQRNTTGNSIGATRAHEVHIDTTNPRYTPKLGSVLMYSESTDFDDG
QPTRFTPIGMGADDWHQWELPEYSGHLTLNMNLAPAVAPAFPGERILFFRSVVPSAGG
YGSGHIDCLIPQEWVQHFYQEAAPSQSAVALIRYVNPDTGRSIFEAKLHREGFITVAN
SGNNPIVVPPNGYFRFEAWVNQFYTLTPMGTGQGRRRVQ"
gene 6722..7498
/gene="ORF3"
CDS 6722..7498
/gene="ORF3"
/codon_start=1
/product="VP2"
/protein_id="AWR17816.1"
/translation="MAGAFLAGLAGDAITSGVGSLINAGANAINQKVEYDFNKQLQLA
SFKHDKEMLQSQVLATKQLQQEMINIRQGVLSAGGFSPTDAARGAVNAPMTKILDWNG
TRYFAPNSMKTTSYSGQFSSNPVHRQPTLPRSEPPKIKVNSDSASVYSSTSTAPSQST
HSTALTAGSSSSRTTSSSAVASTLSRTSDWVRGQNERLSPFMDGALQTTFVTPPSSKA
SSYGSVSTVPKAVLDSWTPMFNTHRQPLFAHVRRRGESQI"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgctac cactgccttt ggcagccaaa actctgtcaa
61 tgacagtatc aacaccgccc cttctaataa agaagaggtt ggtgcattct ccaacatcaa
121 agttggtttt aagaaaatgc tgggtgccgt tcctaagggg accaaagcac ccagtagtga
181 tcaacactgc ccctcattta aagtcgggac caagacatta acagttcccc ctgagccccc
241 aaatggtgaa gacaccgtgc agtttgatgc gaagtcggaa actgtgcgcg ggttaccaga
301 cttgacaacg gtgcagaatg aacacgaaaa cacaccatac actgtccccc cattgagtga
361 aagggagcac agaccagcta ctgaaccgct tcctggcaca atactggaga tgtgggatgg
421 tgaattctac cattactctg tgtacgtcag cggtggcaaa gccctagggg ttcacaagcc
481 ccctgcagcg ataagcctcg cgacgataga gctcacaccc atatctcttt attggaggcc
541 cgtttacacc cccaactatc tggtctgccc agacacgttg aagggccttg ctggtgagaa
601 gttcccttac acggccttca gcaacaactg ttacaacttc tgttgctggg tgcttgagct
661 caatgacaca tggcttagta ggagaagcat ctctaggacc accggcttct tcaaaccaca
721 ccagtcttgg aataggaaac cccttccaac cgttgatgat ggaaagatca aaaaggtggc
781 caacgcaatt ctctgtgcac ttgggtcact gttttcaaaa ccaatcaagg acctattggg
841 caagcttaaa ccattgaact tgctgcactt gctcgcatca tgtgactgga cgtttgcggg
901 tatagtagag acagtcatcc taatggcgga acttttcggc atcttttgga caccgccaga
961 tgtttccagt ttcatagcct ccctgatagg tgattttgaa ttgcaagggc ctgaggacct
1021 ggctgtggag cttgtacccg tggtcatggg tggcatagga atggttctcg gctttactgc
1081 tgagaagata ggccgcatgt tatcgtccgc tgcatcaaca ctacgggcgt gcaaagactt
1141 ggggaattat gctcttgaca tattgaaatt agttatgaag tggttcttcc caaagaaaga
1201 agagaaagcc gagatggaaa ccctaagggc gattgaggat gccgtcctgg acatggaagc
1261 tataggaaac aaccatctca caaccctcct caaggataag gatagcctca cggctttcat
1321 gaagactcta gatctagaag aagagaaggc aaggaagctg tccaccaaat catcctcgcc
1381 agacattgtt ggcaccatta atgccatact agctagaata gctgctgcca ggtccctctt
1441 gcacaaggct aaagaagaaa tgttcagcag gaccagaccc gtggttgtca tgatctcggg
1501 tagacctggc attggcaaaa cccacatggc aagacacttg gctaagagta tcgccaacac
1561 catgagcggc gaccagagag tggggctcgt tccacgcaac ggggttgatc attgggatgc
1621 ctacagggga gagagggtgg ttttatggga tgattacggc atgggaaacc ctgtcaaaga
1681 tgccctaaca ctgcaagagc tggccgacac ctgcccagta actctaaact gtgataggat
1741 tgagaacaag gggaagatgt ttgacagtga tgtcatcata atcacgacca atttagtcaa
1801 cccagcgccc ctcgattatg taaacttcga ggcgtgctcc agaagggtcg actttctggt
1861 ctatgcagag tcaccagaaa ttgagaaggt taagagagac ttccccggcc aacctgacat
1921 gtggaaggac cattttaagc cagacttttc ccacataaaa ctgactctag ccccacaagg
1981 tgggtttgac aagaatggca acaccccgca tggtaagggc accatgcgat ccctaaccca
2041 ggggtccctg actgcaaggg ttgcaggtct tgttcatgag aggagagacg agtttcagct
2101 ccaggggaac aaccttcaaa catataactt tgacaccaac agagtctctg cgtttaggaa
2161 gctggccgca gacaacaagt atgggatcat ggagactatg agagtgggca cagcgcttaa
2221 gagtgtcaag accttggaag atctgaaagt tgcactgagg gatgtgaagt tcaatgagtg
2281 tgagataatt tacagaaact ccaaataccg agtctcttcc aatggtaaag gttctgtctc
2341 tgttgacaaa gttgaggacc aaacatccca gaccgcaaac gaagtgggtg cagcactcct
2401 tagactcaga caggcaagag ctagatacta tgtcagctgc ttccaagacc tcgtctacac
2461 tctaatacag gttgccggag catcattcgt tgtcaacagg atctctaaaa ggttctgctg
2521 ggagagatgg gtcaaaccaa ccgagaccca ggaaacgagt gaatccgaaa aggaagtggc
2581 ccaaggcaga tgggagattg agcccaggga cacagaacca gaaggtaaga agggtaagaa
2641 caagaaagga agaggcaaga aacacacagc tttctccagt aaaggcctga gtgatgagga
2701 gtatgacgag ttcaagagaa tcagagaaga aaggaacgga aaatattcca ttgaggaata
2761 cctgcaagac cgggatcgct actatgagga agtggcggtt gcccgggcga cagaggagga
2821 cttctgtgaa gaggaggagg ccaagataag acaaagaatc tttcgcccca caaagaaaca
2881 gaggaaggaa gaaagggggg tgcttggttt ggttactggc tcagacatca ggaagagaag
2941 gccggacgac tttcaaccga agggcaaccc gtgggcagac gacaccagga gcgtggacta
3001 caacgagaga cttgatttcg aggctccccc gagtgtctgg tcaagaatag tcccattggg
3061 cactggctgg ggcttctggg tctcatcaaa cctcctgatc acaacaacgc acgtcctacc
3121 taaggggatt aatgaactct ttggagttga gatcaaacag attcaggttc ataagtctgg
3181 ggagttctgc aggttcagat tcccaagacc aattagacca gatgtcacag ggctcgtgtt
3241 ggaggaaggc gctccagaag gcactgtctg ctccatactc gtaaagagac ccacaggtga
3301 gatgatcccc ctggcagtga ggatgggcac gcatgcatcc atgaaaatac agggtaggac
3361 cgtcggtggc cagatgggaa tgctcctcac aggggcaaat gcgaagaaca tggatcttgg
3421 caccggtcct ggtgactgcg gttgccctta catctacaaa cgtggcaatg atatagttgt
3481 cgcgggtgtc cacaccgcag cagcccgggg aggcaacact gtcatatgtg ccactcaagg
3541 gcaagatggg gaagcagtcc ttgagggaaa tgagaacctt ggcacttact gcggtgctcc
3601 aatcttgggt ccaggcaagg cgcccaaact tagcacgaaa accaagttct ggcgttcatc
3661 accagacgct ttgccgccag gcacttatga gcctgcctac ttgggaggta aggaccctag
3721 agtggagaaa ggaccatccc tgcagcaagt catgagggac cagctaaaac ccttcacaga
3781 acccaggggt aagccaccta gacctgcagt cttagaagaa gccaaaaaga cagtgatgaa
3841 tgttctagag caaaccattg accctgctaa accgtggacc tattcccaag catgcgcctc
3901 actggacaag accacttcca gtggtagccc ccatcatgtc aggaaaaacg accattggaa
3961 tggggaatcc ttcactggcc ccctcgcaga ccaagcatcc aaagccaacc tcatgtacga
4021 gcaggccaaa catgtgcagc ccgtgtacac ggccgcactt aaagatgaac tagtcaaaac
4081 tgacaagatc tacaagaaga taaagaaaag gctcttatgg gggtcggacc ttggtacaat
4141 ggtcaggtgt gccagggcct ttggcggtct catggatagc atgaaggcaa gctgcatagc
4201 cctcccatgt agggtaggaa tgaacatgaa tgaagatggc cccatcatat ttgacaagca
4261 ttctaagtat aggtaccatt atgatgctga ctattccagg tgggactcaa cccagcaaag
4321 gagcattctc tcggccgcta tggaagtgat ggtgcggttc tctgctgaac cagagctggc
4381 acaagtggtt gcagaggacc tcctggcacc cagccaacta gatgttggcg attttgtcat
4441 ctcagtccag gagggtctgc catcaggggt tccatgcaca tcacaatgga attcaatagc
4501 gcactggatc ctaaccttga gtgcaatggc agaagtatcg ggtctctcac cagatgttat
4561 tcaagcccac tcctgtttct cattctacgg tgatgatgag atcgtcagca ctgacatcaa
4621 ccttgatccc atgaagttga cacagaagct tagagagtat ggcctggtcc ccacccgacc
4681 tgacaaaact gagggtcccc tcgtaataac tgaagatctc accggcctaa cgttcctgcg
4741 taggtcaatt gcacgggacc cagctgggtg gtttggaaaa ttggaccaag actcaatcct
4801 caggcagttg tactggacaa ggggccccaa ccatgagaac ccatatgaga gtatggtccc
4861 tcattcccag cgggccacac aacttatggc ccttctcggt gaggcctcac tgcatggtcc
4921 ccagttttac aagaaagtta gcaagatggt tattaatgag atcaaaagtg gtggtctgga
4981 attctatgtg cccagacaag aggccatgtt tagatggatg agattctctg acctcagcac
5041 atgggagggc gatcgcaatc ttgctcccga gggtgtgaat gaagatggcg tcgaatgacg
5101 ctgctccatc gaatgatggt gctgccaacc tcgtaccaga ggccaccaat gaggttatgg
5161 cacttgagcc ggtggtggga gcctcaattg ctgctcctgt cgtcggccaa caaaatataa
5221 ttgacccctg gattagagaa aattttgttc aggcaccaca gggtgagttt actgtttcac
5281 caaggaactc acctggtgag atgcttctaa atcttgaatt aggccctgag ctcaaccctt
5341 atctgagtca cttgtcccgc atgtacaacg gctatgctgg tggtatgcag gttcaggtgg
5401 tcctagctgg gaatgcgttc acagctggta aaatcatctt tgccgccgtc ccaccacatt
5461 tccctgttga gaacattagt gcagcccaaa tcacaatgtg cccccatgta attgttgatg
5521 taagacagct tgagccagtg cttttgcccc tccctgacat aaggaatagg ttctttcatt
5581 ataatcagga aaataccccc cggatgagac ttgtggctat gttgtataca ccccttagag
5641 caaattctgg tgaggatgtg tttacggtgt cttgcagagt tctgactcgc cctgcccccg
5701 actttgagtt cacgttcttg gtgccaccaa ctgtggagtc aaagactaag ccctttacac
5761 tccctattct gactcttgga gagctgtcca actccagatt ccccgctccg atagacatgc
5821 tgtacactga ccccaatgag gcaattgtgg tgcaaccaca aaatggcagg tgcactctag
5881 atggaacact tcaagggacc acccaactgg tacccaccca aatttgctcc ttcaggggca
5941 cgctaattag ccagacgtcg aggtctgcag attcaacaga ttcagcccca cgggtgagga
6001 accaccctct ccacgttcag ctgaagaacc tcgatgggac accatatgac ccaacagatg
6061 aggtgccagc agttttgggt gccatagatt tcaaaggaac tgtgtttggg gtcgctagcc
6121 aaagaaacac cacagggaac tctataggag caacccgcgc ccatgaagtg cacatagaca
6181 ccacaaaccc taggtatacc ccaaaacttg gctctgtgtt gatgtattct gaatctactg
6241 attttgatga tggacaaccc acccgcttta cccccattgg catgggagcc gatgattggc
6301 accaatggga actgcccgaa tattctggtc acctcactct taacatgaat ttggcccccg
6361 cagttgcccc tgctttccct ggtgagcgca ttctcttctt cagatcagtg gtgccgtctg
6421 ctggtggcta tggatcaggt cacatagatt gcctcatccc acaggagtgg gttcagcatt
6481 tctaccagga ggccgctcca tcacagtccg cggtggctct tatcagatat gttaaccctg
6541 acactggaag aagcatcttt gaggcaaaac tgcatagaga agggttcatc actgtggcaa
6601 attctggaaa caaccccata gttgtgcccc caaatggtta cttcaggttt gaggcctggg
6661 tcaatcaatt ctacacactc acccccatgg gaactggaca ggggcgcaga agagttcaat
6721 aatggcagga gctttcttag ctggattggc aggtgacgcc ataacaagtg gtgtcgggtc
6781 cctaatcaat gctggggcca atgcaattaa ccaaaaggta gaatatgact ttaataaaca
6841 gctccaattg gcatccttca aacatgacaa agagatgctg caatcacaag tactggccac
6901 taaacagctc cagcaggaga tgataaacat aaggcaaggg gttttgtccg ctggcggctt
6961 ttcccctaca gatgccgcga gaggtgctgt gaacgcgccg atgacaaaaa ttttggattg
7021 gaatggaaca aggtactttg ccccaaatag tatgaagaca accagttatt cgggccagtt
7081 ttccagcaac cctgtgcata ggcaacccac tttaccccgt tctgaacccc caaaaattaa
7141 ggttaatagt gattctgcta gtgtgtatag ttctacatct actgctcctt cacaatcaac
7201 tcactcaacg gctttgactg cggggtctag ctcatctagg acaacatcct cttctgcagt
7261 agcttccacc ctgtctagga ctagtgactg ggtgagagga caaaatgaaa ggcttagccc
7321 gtttatggat ggtgctctcc aaacaacttt tgtcacacca ccatcgagca aagcttcatc
7381 atatgggtcg gtctcaaccg ttcccaaagc tgttttggac tcctggactc ctatgttcaa
7441 tacccatagg cagcctctct tcgctcatgt gcgtaggcga ggggagtcac agatttagtg
7501 aaaagattga ttaggttttc tttctttctt cttttccttt tctttctttt
//