Typing tool
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Typing tool
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Complete norovirus genomes
| MH218651 | GII.13 | |
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| GII.P21 |
ORF1: 5..5104
ORF2: 5085..6713
ORF3: 6713..7444
LOCUS MH218651 7484 bp RNA linear VRL 11-JUN-2018
DEFINITION Norovirus GII isolate NORO_183_23_09_2015, complete genome.
ACCESSION MH218651
VERSION MH218651.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7484)
AUTHORS Brown,J.R., Roy,S., Shah,D., Williams,C.A., Williams,R., Dunn,H.,
Hartley,J., Harris,K. and Breuer,J.
TITLE Norovirus transmission dynamics in a paediatric hospital using full
genome sequences
JOURNAL Clin. Infect. Dis. (2018) In press
PUBMED 29800111
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7484)
AUTHORS Brown,J.R., Roy,S., Shah,D., Williams,C.A., Williams,R., Dunn,H.,
Hartley,J., Harris,K. and Breuer,J.
TITLE Direct Submission
JOURNAL Submitted (17-APR-2018) Division of Infection and Immunity,
University College London, 90 Gower St, London, London WC1E 6BT,
United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 10.1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7484
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="NORO_183_23_09_2015"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="United Kingdom"
/collection_date="23-Sep-2015"
/note="genotype: GII.P21_GII.13"
gene 5..5104
/gene="ORF1"
CDS 5..5104
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="AWR17611.1"
/translation="MKMASNDASAAAAANSNNDNAKSSSDGVLSNMAVTFKRALGARS
KQPPPRDTPPRPPRPPTPELVKQIPPPPPNGEDEPTISYSVKEGVSGLPELSTVTQPE
ESSTAFSVPPLSQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LAKVELSPLSLYWRPVYTPQYLISPDTLRKLHGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMVQRTTGFFRPYQDWNRKPLPTMDDSKVKKVANVLLCALSSLFTRPIKDIIGK
LKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKDETNELAMVRSIEDAVLDLEAIENNHMTALLKDKDSLAAYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRLRPVVVMISGRPGIGKTHLAREL
AKKIASSLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPEVEK
AKRDFPGQPDMWKDTFKPDFSHIKLTLAPQGGFDKNGNTPHGKGVMKTLTASSLVARA
SGLLHERLDEYELQGPTPTTFNFDRNKVLAFRQLAAENKYGLVDTMRVGSQLKNVKTT
TELKQVLKNITVRKCQLVYGGSTYTLESDGKGNVCVERVKNTSVQTNNELSGVLHHLR
CARIRYYVKCVQEALYSILQIAGAAFITTRIAKRMNIQNLWSKPQVEDLEETSNKEGC
SKPKDDEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNEKLDFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPKGAQEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRAVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEAMLEGGDDKGTYCGAPILG
PGNAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPQRWTYAQACASLDKTTSSGHPHHMRKNECW
NGEAFTGRLADQASKANLMYEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
STMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVMDVGDFKISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTVKLK
EYGLKPTRPDKTEGPLIISEDLDGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPSETMIPHSQRPIQLMSLLGEAALHGPSFYSKISKLVISELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 5..994
/gene="ORF1"
/product="p48"
mat_peptide 995..2092
/gene="ORF1"
/product="NTPase"
mat_peptide 2093..2629
/gene="ORF1"
/product="p22"
mat_peptide 2630..3028
/gene="ORF1"
/product="VPg"
mat_peptide 3029..3571
/gene="ORF1"
/product="Pro"
mat_peptide 3572..5101
/gene="ORF1"
/product="RdRp"
gene 5085..6713
/gene="ORF2"
CDS 5085..6713
/gene="ORF2"
/codon_start=1
/product="VP1"
/protein_id="AWR17612.1"
/translation="MKMASNDAAPSNDGAASLVPEAINETMPLEPVAGASIAAPVAGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAIPPNFPVDMISPAQITMLPHLIVDVRTLEPIMIPLPD
VRNVFYHFNNQPQPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFIYLVPP
SVESKTKPFTLPILTISELTNSRFPIPIEQLYTAPNENNVVQCQNGRCTLDGELQGTT
QLLSSAVCSYRGRTVANSGDNWDQNLLQLTYPSGATYDPTDEVPAPLGTQDFSGILYG
VLTQDNVSESTGEAKNAKGVYISTTSGRFTPKIGTIGLHSITENVHPNQQSRFTPVGV
AQNENTPFQQWVLPHYAGALALNTNLAPAVAPTFPGEQLLFFRSRVPCVQGLRGQDAF
IDCLLPQEWVNHFYQEAAPSQADVALIRYVNPDTGRTLFEAKLHRSGFITVSHTGTYP
LVVPPNGHFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6713..7444
/gene="ORF3"
CDS 6713..7444
/gene="ORF3"
/codon_start=1
/product="VP2"
/protein_id="AWR17613.1"
/translation="MAGAFIAGLAGDMLTSAVGSLTSAGANAINQKLNFDYNKQLQNA
SFQHDKEMLQAQIDATKKLQSEMIAIKHGVLTAGGFSPADAARGAVNAPMTRVLDWSG
TRYYAPNSVQTTSYSGQFTPSPVHRAQVKSPSNSSQRTAAPSSIRSLSTQSTSLGSTS
SGGSSTASSSSRTADWVQQQRALSPYMQGALQTAYVTPPSSRASSMSSVSTVPKGVLD
SWTPVFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc tgctgccgct gctgccaaca gcaacaacga
61 caacgcaaaa tcttcaagtg acggtgtatt atccaatatg gctgtcactt ttaaacgagc
121 cctcggggcg cggtccaaac aaccgccccc gagggacaca ccaccaagac ccccgagacc
181 acccacacca gagttggtta aacaaatccc ccctccccca cccaacgggg aggacgaacc
241 aaccatttct tacagtgtca aagagggtgt ttctggtttg cctgaactct caacggtcac
301 ccaaccggaa gagagctcta cggcattcag cgttccccct cttagtcaaa gggagaacag
361 agatgcaaag gaacccctaa ctggaaccat cctggagatg tgggacgggg agatctacca
421 ttatggctta tatgtggaac gaggactagt gctcggtgta cacaaaccac cagcagccat
481 cagccttgcc aaggttgaac tgtccccctt gtctttgtac tggagacctg tgtacacccc
541 acagtacctc atttcccctg acactctaag aaaattacat ggggagacgt tcccttacac
601 agcctttgac aacaactgtt atgccttctg ctgttgggtt cttgacttga acgattcatg
661 gctgagcaga aggatggtac agaggacaac gggcttcttt cggccctacc aggactggaa
721 cagaaaaccc ctccccacaa tggacgactc caaagtgaag aaggtggcca atgttctcct
781 ctgtgctctc tcatcattgt tcactagacc aattaaggac attattggaa agttgaaacc
841 cctaaatatc ctcaacatcc tagccacatg tgattggact tttgcaggca tagtagagtc
901 cctgatcctc ttggctgaac tgtttggagt tttctggaca cccccagatg tgtctgcaat
961 gatcgctccc ttactgggtg attacgagct acaggggcct gaggacctcg ctgtggaact
1021 cgttcctgta gtaatgggag ggataggttt ggtgctggga ttcaccaaag agaaaattgg
1081 caaaatgctt tcatctgctg cttcaaccct gagggcatgc aaagatctcg gagcttatgg
1141 gctggagata ctcaaattgg tcatgaagtg gtttttccca aagaaagacg agacaaacga
1201 gttggcaatg gtgagatcca tcgaggacgc agtgttggac ctcgaggcca ttgagaacaa
1261 ccatatgaca gctctactca aggataagga cagccttgct gcctacatga ggactcttga
1321 cttggaggag gagaaggcga ggaagttgtc caccaagtct gcatcaccgg acatcgtggg
1381 cacgatcaat gccctactgg caaggattgc agctgcccgg tctctagtac acagggctaa
1441 ggaagaactg tctagcagac ttcgaccggt cgttgtgatg atttcaggga gaccaggtat
1501 agggaagacc catctagcta gagagttggc aaagaagatc gcctcctcac tcacaggtga
1561 ccagagggtg ggcctcatcc cacgcaacgg ggtcgaccac tgggatgcat acaaaggtga
1621 aagagtcgtt ctctgggacg actacggaat gagcaaccct atccacgacg ccctcagact
1681 ccaggagctt gctgacacct gccccctaac acttaactgt gacaggattg aaaacaaagg
1741 taaagtcttt gacagtgacg ccataataat aaccaccaat ttggccaacc cagcgccact
1801 ggattatgtc aactttgaag cttgctcaag acgcatagac ttcctcgtct atgctgatgc
1861 ccctgaagtt gagaaggcca aacgagactt cccaggccag ccagacatgt ggaaggacac
1921 cttcaaacct gacttctcac acataaaact gacattagcc ccgcaaggag gttttgacaa
1981 gaacggcaat acccctcatg ggaagggtgt tatgaagacc ctcactgcta gttccctcgt
2041 tgcccgagca tcagggctcc ttcacgagag actagacgag tatgagctac aaggcccaac
2101 tcccacaaca ttcaacttcg accgcaacaa ggtgcttgct tttaggcaac tcgctgctga
2161 gaacaagtac ggtctcgttg acacaatgag ggtcggatca caactcaaga acgtcaaaac
2221 cacgacagaa cttaaacagg ttctcaagaa catcacagtc aggaaatgcc agcttgtgta
2281 tggcgggagc acatacacac tcgaatctga tggcaaaggc aatgtgtgtg ttgaaagggt
2341 gaagaacaca agtgtgcaga ctaacaacga gctctccggc gttctgcacc atctcaggtg
2401 tgccaggatt aggtactatg ttaagtgtgt tcaggaagct ctctactcca tcttgcaaat
2461 tgccggggct gcattcatca ccacgcgcat tgcaaagcgc atgaacatac agaacctatg
2521 gtcaaagcca caagtggaag atttggagga gactagcaac aaggagggct gttcaaaacc
2581 taaagatgac gaggagtttg ttatctcctc tgatgacatc aaaactgagg gcaagaaagg
2641 aaagaacaag actggccgtg gtaagaagca cacagccttt tccagcaaag gtctcagtga
2701 tgaggagtac gatgagtaca agagaatcag agaagagaga aatggcaagt actccataga
2761 ggaataccta caggacagag acaagtacta tgaggaggta gccatagcca gagcaactga
2821 ggaggatttc tgtgaggaag aggaggccaa aatccggcaa aggatattta gaccaacaag
2881 aaagcaacgc aaagaggaga gggcctccct tggtttggtc acaggttctg agattaggaa
2941 gagaaatcca gatgacttca aacctaaagg gaagctatgg gctgatgatg acaggagtgt
3001 tgactacaat gagaaacttg actttgaggc tccaccaagc atttggtcac gaatagtcaa
3061 ctttggctca gggtggggct tttgggtctc gcctagcctc ttcataacat caacccacgt
3121 cattcccaaa ggcgcacagg agttctttgg agtgcctatt aagcaaatac aaattcataa
3181 atcaggagag ttctgccggc ttagatttcc aaaaccaatc aggaccgatg tcacgggcat
3241 gatattagag gaaggtgctc cagaaggaac tgttgccaca cttctcatca agagaccaac
3301 tggggaactc atgcccttgg cagccagaat gggtacccac gcgaccatga aaatccaggg
3361 tcgcgctgtt ggtgggcaga tgggcatgct actcacgggg tctaatgcca agagcatgga
3421 tttgggcaca actcctggtg actgtggctg tccctacatc tacaagaggg ggaacgacta
3481 cgtggtcatt ggagtccaca ccgccgctgc ccgtggagga aacactgtca tctgtgcaac
3541 ccaaggaagt gagggtgaag ccatgctaga gggtggcgac gataagggaa cctactgtgg
3601 agcaccaata ttaggccctg gaaatgcccc caaactcagt accaaaacca aattctggag
3661 gtcttctacc acccccctgc cacccggaac ttatgaacca gcttatctgg gtggcaagga
3721 ccccagagtg aagggtggtc cctcactgca acaggttatg agggagcaat taaaaccatt
3781 cactgagccc agaggcaaac cacccaaacc tagtgtgcta gaagctgcca agaagactat
3841 aatcaatgtg cttgaacaga caatagaccc acctcaaaga tggacatacg cacaggcgtg
3901 tgcatcacta gataaaacta cttccagcgg ccaccctcac cacatgcgga agaacgagtg
3961 ctggaacgga gaggctttca caggaagatt ggcagaccaa gcatcaaaag ctaacctaat
4021 gtatgaggaa ggaaagaaca tgaccccagt atacacagga gccctgaagg acgaactagt
4081 caagactgat aagatctatg ggaagatcaa aaagagactc ctgtggggtt cggacctatc
4141 aaccatgata cggtgtgcac gagctttcgg tgggctgatg gacgaactca aggcccattg
4201 cgtcacacta ccagttaggg ttggcatgaa catgaatgaa gatggaccca taatatttga
4261 gaaacattcc agatacagat accattatga tgcagattac tctcgctggg actcgacaca
4321 gcaaagagca gtgctggctg cagccctaga aataatggtc aaattttcac cagaacccca
4381 tctggcccaa gtagttgcag aagacctctt gtcccccagt gtgatggatg tgggtgattt
4441 caagatttca atcaatgagg ggctaccctc tggtgtgcct tgcacttcac aatggaactc
4501 cattgcccac tggctcctca cactatgtgc attatctgag gttacagacc tgtcccctga
4561 catcatccag gcaaactccc tgttctcctt ttatggtgat gatgaaatag tgagcacaga
4621 catcaaattg gacccagaga aactgacagt aaagttgaag gaatacgggt taaaaccaac
4681 ccgtcctgat aaaacagaag gacccttaat tatctctgaa gatttggatg gcttgacctt
4741 cttacggaga acggtgaccc gtgatccggc tgggtggttt ggcaaactgg accaaagttc
4801 aatactcagg caaatgtact ggaccagggg accaaaccat gaggacccct ctgaaacaat
4861 gataccacac tcccaaagac ccatacaact gatgtcacta ctaggtgaag ctgcactaca
4921 tggcccatca ttctacagta aaatcagcaa gttggtcatc tcagaattga aagagggtgg
4981 gatggacttt tacgtgccca gacaagaacc aatgtttagg tggatgagat tctcagactt
5041 gagcacgtgg gagggcgatc gcaatctggc tcccagtttt gtgaatgaag atggcgtcga
5101 atgacgccgc tccatcgaat gatggtgcag ctagtctcgt accagaggcc attaatgaga
5161 ctatgccatt ggaacccgtt gctggtgcat ctattgctgc cccagtggcg ggacaaacta
5221 acataattga cccctggata agaacaaatt ttgtgcaagc ccctaatgga gaatttacag
5281 tgtcacccag aaattcccct ggagagattc tgctaaattt agagttggga ccagatttga
5341 atccttattt ggcccatcta tcaagaatgt acaatggata tgctggaggt gttgaggtgc
5401 aagtgcttct tgctgggaac gcgttcacag caggaaagat attatttgca gcaatcccac
5461 ccaactttcc tgtagatatg attagcccag ctcaaattac tatgcttccc catttgattg
5521 tagatgttag gacattggaa cctattatga tacccttacc tgatgttagg aatgtgttct
5581 accattttaa taatcaaccc caacctagga tgagattagt ggctatgctc tataccccat
5641 tgagatctaa tggttcagga gatgatgttt ttactgtgtc ttgtagagtg ttgactaggc
5701 caacccctga ttttgaattc atttacctag tgcctccctc tgtagagtcc aaaactaaac
5761 cattcacact cccaatattg accatttctg aactaaccaa ctcccggttt cccatcccaa
5821 ttgagcaact gtacacggcc ccaaatgaga ataatgttgt acagtgtcaa aatggaaggt
5881 gcaccttgga tggagaactt cagggcacca cccagctgct atcaagtgca gtttgctctt
5941 acaggggcag gactgtggct aacagtgggg acaattggga ccaaaatttg ctccagctga
6001 cctacccaag tggtgcaacc tatgacccca ctgatgaagt accagcaccc ttgggcaccc
6061 aagatttcag tgggatattg tatggggtgt taacccaaga caatgtaagt gagagtacag
6121 gggaggccaa aaatgctaag ggggtataca tatccaccac cagtggaaga ttcaccccaa
6181 aaattgggac aattggattg cattcaataa ctgaaaatgt gcaccccaat cagcaatcac
6241 ggttcacccc cgttggggtc gctcagaatg aaaacacccc cttccagcaa tgggttctac
6301 cacactacgc aggtgctctc gctctaaaca ccaatttggc acccgctgtt gccccgactt
6361 tccctggcga gcaattgctg ttcttcaggt cccgtgttcc atgtgttcaa ggtctgcggg
6421 ggcaggatgc tttcatagac tgtctcctac ctcaagagtg ggtgaaccat ttttatcaag
6481 aggctgcccc ctcccaagca gacgtcgccc tcatcaggta tgtcaaccct gatactggtc
6541 gcacgctgtt tgaggccaaa ttgcacaggt caggtttcat tactgtatca cacactggta
6601 cctaccctct tgtggtcccc ccgaatggtc attttaggtt tgattcttgg gttaaccaat
6661 tctactcact cgcccccatg ggaactggca atgggcgcag aagagttcaa taatggcagg
6721 agcatttata gctggtctag ccggtgacat gctgacttct gctgttggtt cactgacctc
6781 tgcaggagcc aatgccatca atcagaaatt gaattttgat tataataaac aactccaaaa
6841 tgcatccttt caacatgata aggaaatgtt gcaggcccaa attgatgcta caaagaagct
6901 ccaatcagaa atgattgcaa tcaagcatgg ggttttgacc gcgggcggct tttccccagc
6961 tgatgcagcc agaggggcag tcaacgcccc aatgactcga gtgttggatt ggtcagggac
7021 acgctactac gctccaaatt ctgtgcaaac caccagttat tctgggcaat tcaccccctc
7081 gccagtccat cgggcgcagg tgaagtcccc ttccaattca tcccagcgga ctgcagctcc
7141 aagcagtatc cgcagcctgt caacccaatc aacttcttta ggctccacct cctcaggggg
7201 gtcctctaca gcctcctcta gttcgaggac ggcagattgg gtgcaacaac aaagggctct
7261 tagcccgtac atgcagggag ccctgcagac ggcatacgtc acaccgccgt ctagtagggc
7321 ttccagtatg agctctgtct caacagtgcc caaaggggtt ttggactcct ggacacctgt
7381 gtttaacaca cgcaggcagc cgctgtttgc acacctcagg aagagggggg agtcacaggc
7441 ttagtgaaaa ggataatcaa tttttaaaat gtgattttat tttc
//