Typing tool
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Typing tool
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Complete norovirus genomes
| MG746007 | GII.2 | |
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| GII.P16 |
ORF1: 5..5104
ORF2: 5085..6713
ORF3: 6713..7492
LOCUS MG746007 7536 bp ss-RNA linear VRL 06-APR-2018
DEFINITION Norovirus GII isolate CQ006, complete genome.
ACCESSION MG746007
VERSION MG746007.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7536)
AUTHORS Ao,Y., Cong,X., Jin,M., Sun,X., Wei,X., Wang,J., Zhang,Q., Song,J.,
Yu,J., Cui,J., Qi,J., Tan,M. and Duan,Z.
TITLE Genetic Analysis of Re-Emerging GII.P16-GII.2 Noroviruses in
2016-2017 in China
JOURNAL J. Infect. Dis. (2018) In press
PUBMED 29617875
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7536)
AUTHORS Ao,Y.
TITLE Direct Submission
JOURNAL Submitted (26-DEC-2017) Department of Viral Diarrhea, National
Institute for Viral Disease Control and Prevention, Chinese Center
for Disease Control and Prevention, 155 Changbai Road, Chang-ping
District, Beijing 102206, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7536
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="CQ006"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="China"
/collection_date="05-Jan-2017"
/collected_by="Yuanyun Ao"
/note="genotype: GII.P16-GII.2"
5'UTR 1..4
CDS 5..5104
/note="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="AUY62104.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGIFGLPELTTVPQ
PDVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
VSMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYRGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEV
EKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMRVGNQLKGVK
TMEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESEIKEE
APKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIRIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPAGITEAFGVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIAIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKQTIINVLEQTLDPPQNWTYAQACASLDKTTSSGHPHHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKVYGKIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLR
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 5..1000
/product="p48"
mat_peptide 1001..2098
/product="NTPase"
mat_peptide 2099..2629
/product="p22"
mat_peptide 2630..3028
/product="VPg"
mat_peptide 3029..3571
/product="Pro"
mat_peptide 3572..5101
/product="RdRp"
CDS 5085..6713
/note="ORF2; major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="AUY62105.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
CDS 6713..7492
/note="ORF3; minor structural protein; minor capsid
protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="AUY62106.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GPSHGTVSSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMYGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
3'UTR 7493..7536
ORIGIN
1 gttaatgaag atggcgtcta acgacgctac cgttgccgtt gcttgcaaca acaacaacga
61 caaagaaaaa tcttcaggtg aaggcttatt cacaaatatg tcttccacct taaagaaagc
121 cctcggggct aggcccaaac agcctgcccc gagagacaaa ccacaaaagc ccccaagacc
181 accaactccc gagttggtca agaggatacc ccctcctcca cctaatggcg aagaagaaga
241 agaaccagtc attaggtatg aggttaagag tgggatcttt ggcctgcccg agctcacaac
301 agtcccccaa ccggacgtgg ccaacacagc attcagtgtt ccaccactga gcttgagaga
361 aaacagggag gccaaggaac cgctaacagg ggcaatatta gagatgtggg atggagagat
421 ataccactat ggcctgtacg tggagaaagg cttagtgttg ggtgtgcaca aaccacccgc
481 agccgtaagc atggcaagag tggagctgac gccgctgtca ttgtactggc gtgtggtgta
541 cactccccaa tacctcatct cccctgaaac tctcaggaga ctcaatggag aggcattccc
601 ttacaccgcc tttgacaata actgctatgc cttttgctgc tgggtgttag acctcaatga
661 ctcatggctt agcaggagga tggtgcaaag aacaacgggc ttcttcagac cttaccaaga
721 gtggaacaga aaacccctgc ccaccatgga tgactccaaa attaagaagg tagcaaatat
781 attcctatgt tcattgtcca cattattcac cagacccata aaagacctca taggaaaaat
841 taaaccatta aacatattga atatcctggc aacgtgtgac tggacctttg ccggaatagt
901 ggagtctctg atattacttg ctgaactctt cggagttttc tggacacccc cagatgtgtc
961 tgctatgatc gctcccttac tcggggacta cgagttgcag gggccagaag acctcgccgt
1021 tgaactcgta cctgtggtaa tgggggggat tggtttggtg ttgggattca ccaaagagaa
1081 aatcggcaaa atgttgtcct cagcagcatc aacactcagg gcttgcaaag atcttggtgc
1141 ctatggctta gagatactta aattggtcat gaagtggttc ttcccaaaga aagaggaggc
1201 caatgagtta gccatggtga gggccataga ggatgctgta ctagatcttg aggcaataga
1261 aaacaaccac atgacaaccc tgttgaaaga caaagacagc ttagcaacat acatgaaaac
1321 actggacatg gaggaggaga aagccaggag gttgtccaca aaatctgcat cccctgacat
1381 agttgggaca attaacgccc tgctggctcg aatagcagcg gccaggtcat tagtccacag
1441 ggccaaggaa gagctatcta gcaggataag accagtagtt gttatgatat ctggcaaacc
1501 aggaataggc aaaactcatc tggccaggga ggtggcaaga aaggtggcat ccactctcac
1561 aggggatcaa agagtcggac tcataccaag aaacggtgtg gaccattggg atgcatacag
1621 aggtgagaga gtcgtgctgt gggacgacta tggcatgagt aaccccattc atgatgctct
1681 tcgcatacaa gaattggctg atacgtgtcc ccttacctta aattgtgaca gaattgaaaa
1741 taagggaaaa gtttttgaca gtgaggtcat aataataaca acaaaccttg ccaatccagc
1801 cccacttgat tatgttaact ttgaggcctg ttccaggaga attgatttcc tggtgtacgc
1861 tgaggcacca gaagtagaaa aggcaaaacg ggactttcct ggtcagccag atatgtggaa
1921 ggacgccttc aagccggact tttcacacat caagctacag cttgcacccc agggcggctt
1981 tgacaagaat ggcaacaccc cacatgggaa aggagtgatg aagaccctca ctaccggttc
2041 tctgattgcc cgtgcatcag gcctactgca tgagaggatg gatgaatttg aactccaagg
2101 tcccacaatc accaccttca atttcgaccg gaacagaatc acagcattca gacaattggc
2161 tgcagaaaac aagtatggat tggtggatac catgagagtt ggcaatcaac taaaaggagt
2221 gaaaaccatg gaggaactta aacaagcaat caggaatgtg accatcaaga ggtgccggat
2281 catctacggt ggctccacgt atgaccttga atctgatggc aagggcaaag ttttggtgga
2341 aaaggtcaag aacacctctg tacagaccaa caacgagttg gctggggccc tgcaccatct
2401 caaacatgcc cgaatcaggt actatgtcaa atgtgtgcaa gaagcagtct actccatcat
2461 acaaattgcc ggcgctgcgt ttgtcaccac gcgcattgca cgccgcatga acatacaaga
2521 actctggtcg aagccacaat tagatcaaaa tgaatcagag attaaggaag aggcccccaa
2581 gtcagaagat gacgagttca tcatatcttc taaggacatc aaggaggaag gaaagaaggg
2641 caaaaacaaa actggccgtg gcaagaaaca cactgcattc tccagcaagg gcttgagcga
2701 tgaggagtat gacgagtaca agaggataag agaagagaga aatgggaagt actctataga
2761 ggagtatctt caagacagag acaggtacta tgaggagctc gccattgcca aggccacgga
2821 agaagacttt tgtgaagagg aggagatcag aatccgtcag agaattttcc gtcccaccag
2881 gaaacaaaga aaggaagaga gggccacatt agggctagta acaggttcag aaattagaaa
2941 aagaaaccct gatgacttca aacccaaagg gaagctgtgg gccgatgaca acaggagtgt
3001 tgactacaat gagaaactgg actttgaggc ccccccaagc atatggtcta ggattgtgag
3061 ctttggttct ggctggggct tctgggtgtc accaagcctt ttcataacat caactcatgt
3121 aatccccgca ggcataacag aagcatttgg agtccccatc aaacaaattc agatccacaa
3181 atcaggtgaa ttttgccgat tcagattccc aaaaccaatt agaccagatg tgacaggaat
3241 gatcttggaa gaaggtgcgc ctgagggcac cgtggcaact gtgctcatca aacgccccac
3301 cggagagctc atgcctcttg cagccagaat gggaacacac gcaaccatga aaattcaagg
3361 ccgcatggtt ggcggacaga tgggtatgtt gctcactgga tcaaatgcta aaggaatgga
3421 tttgggaacg actcctggtg actgtggctg cccttacatc tataagaggg gcaatgacta
3481 tatagccatt ggggtgcaca ctgcagcagc ccgtggtgga aacaccgtca tctgtgccac
3541 acagggaagt gagggtgagg caactcttga gggtggagat gacaaaggaa catactgtgg
3601 ggcgcccatt ctaggccctg ggggtgcacc aaaactgagc accaaaacca aattttggag
3661 gtcatcgaac acgccccttc caccagggac atatgagcct gcctacctcg gtggccgtga
3721 tccgcgtgtt aagggtgggc cttccctgca gcaagtaatg agagaccagt tgaagccatt
3781 cactgaaccc aggggcaaac ctccaagacc aagtgtattg gaagcagcca aacaaaccat
3841 catcaatgtc cttgaacaaa ccctggaccc cccacaaaat tggacatacg cacaggcgtg
3901 tgcctcactt gacaaaacca cctctagcgg gcatccccat cacgtccgaa agaatgaatt
3961 ctggaatggt gagaccttca ctggtaaact ggcagaccaa gcatcaaaag caaacctaat
4021 gtttgaggaa gggaaacaca tgacaccagt gtacacagca gcactcaagg acgagctagt
4081 caagactgag aaagtctatg gaaagatcaa gaagagactg ctctggggct ctgacttgtc
4141 caccatgatc cggtgcgcta ggtcatttgg cgggctcatg gatgagatga aggcacactg
4201 catatcactc ccagtccgag ttggcatgaa tatgaatgaa gatggcccaa taatatttga
4261 gaaacattcc aggtacaaat atcactatga tgcagactac tctcgttggg attcaacaca
4321 acagagggca gtactagcag cagccttgga aatcatggtc agattctctg cagaaccaca
4381 attggcacaa atagtcgccg aggatctgct ggcccctagt gtagtagatg taggagactt
4441 taaaattaca ataaatgaag ggctcccttc tggtgtgcca tgcacttctc aatggaactc
4501 catcgcacac tggctgctaa ctctctgtgc cttgtctgaa gtcaccaaac tgtcccctga
4561 cattatacag gcaaattcca tgttctcatt ttacggtgat gacgagattg tcagcaccga
4621 cataaaattg gaccctgaac agttaaccgc caaattgagg gagtacggcc tgaaaccaac
4681 ccgcccagac aaaaccgagg gacccctgat tatcagtgaa gatctgaacg gtctcacttt
4741 cctccgaagg acggtgactc gtgacccagc tggctggttt ggaaaactgg accaaagctc
4801 aattttgagg cagatgtact ggactagagg accaaatcat gaagacccca atgagacaat
4861 gataccccat tctcaaagac ccatacagct catggcactt cttggtgaag cctctcttca
4921 cgggccctct ttctacagta aaatcagtaa attggtcata actgaactca aagaaggtgg
4981 gatggacttt tacgtgccaa ggcaggaacc catgttcagg tggatgaggt tttctgactt
5041 gagcacgtgg gagggcgatc gcaatctggc tcccaatttt gtgaatgaag atggcgtcga
5101 atgacgccgc tccatctact gatggtgcag ccggcctcgt gccagaaagt aacaatgagg
5161 tcatggctct tgaacctgtg gctggtgccg ccttggcagc cccggtcacc ggtcaaacaa
5221 atattataga cccttggatt agagcaaatt ttgtccaggc ccccaatggt gaatttacag
5281 tctctccccg aaatgcccct ggtgaagtgc tactgaatct agagttgggt ccagaattaa
5341 atccttatct ggcacattta gcaagaatgt acaatgggta tgccggtggg atggaggtgc
5401 aggtcatgtt ggctgggaac gcgttcacag ccggcaagtt ggtcttcgcc gccgtgccac
5461 ctcacttccc ggttgaaaac cttagcccac agcaaatcac catgttccct catgtgatca
5521 tagatgtgag aaccttggaa cctgttttac taccactccc tgatgttagg aataacttct
5581 tccattataa tcagaaagat gatcccaaga tgagaattgt ggctatgctt tatacccccc
5641 tcaggtctaa tggttcaggt gatgatgtgt ttacagtctc ctgtagagtg ttgactagac
5701 cttcccctga ctttgacttc acatacctgg tgccaccaac agtggagtct aaaacaaagc
5761 cattcaccct cccaatcctc acacttgggg aactttccaa ttctaggttc ccagtgtcca
5821 tagaccagat gtacaccagc cctaatgaag ttatatcagt gcagtgtcaa aatggtaggt
5881 gcacactgga cggggagctc caagggacaa cacaactcca agtcagtggc atttgtgctt
5941 tcaaaggtga agtgaccgcc cacttgcatg acaatgatca cctatataat gttaccatca
6001 caaacttgaa tgggtcccct tttgatccct ccgaggatat ccccgcccct ctgggtgtgc
6061 ctgacttcca gggaagggtt tttggtatca tctcccaaag agataaacac aatagtcctg
6121 ggcataatga accagcaaac aggggacatg acgctgtggt ccctacttac acagcacagt
6181 acactccaaa actgggacaa attcaaattg gcacatggca gactgacgac cttacagtca
6241 accaaccagt caaattcacc ccagttggac tcaatgacac tgaacatttt aaccaatggg
6301 tggtccctag gtatgctggt gccctaaacc tcaatacgaa ccttgcccct tctgttgctc
6361 cagtatttcc aggagagcgc ctgctcttct tcagatcata cattcccctc aagggcggtt
6421 atggaaaccc agccattgat tgcctactac cacaagagtg ggtgcaacac ttctatcagg
6481 aagcagcccc ttcaatgagt gaggtggccc tcgtcagata catcaacccg gacactggtc
6541 gggcactgtt tgaggccaag ctccacagag ctggtttcat gacagtctcg agcaacacca
6601 gtgccccggt ggttgtgcct gccaacggat acttcagatt tgattcttgg gtgaaccaat
6661 tctattctct cgcccccatg ggaactggaa atgggcgtag aagggttcaa taatggctgg
6721 agcttttgta gctggtcttg caggggacgt gctcagcaat gggcttagtt cattaatcaa
6781 tgcaggtgct aatgcaataa atcagagggc agaatttgat tttaatcaga aattgcagca
6841 aaattctttt aatcatgata aggagatgtt gcaggctcag attcaggcaa ctaagcagct
6901 gcaggcagac atgatggcta ttaaacaagg ggtcttgacc gctggcggct tttcccctgc
6961 tgatgcagcc agaggtgctg tgaacgcgcc catgacacag gcgctggatt ggaatggcac
7021 aaggtattgg gcaccaaact ccatgaggac cacatcttat tctggaaaat tcacatctac
7081 cgccccagtg aggcaggctg acttccagca cacccaaagc cggccttcga gtggctcctc
7141 tgtgtcttcc tttgccactc agtcttcaag gccgactctg accacaacca ctggtccctc
7201 acatggcaca gtctcatcaa attcaactcg cagcacaagc ctctcccaat caacggtctc
7261 cagagctaca tctaggactg gtgagtgggt tagagatcaa aatagaaatt tggaacccta
7321 catgtatggt gccttacaga cagcctttgt caccccacct tccagcaggg catctgacgg
7381 gacagtctca accgtcccga aaggtgtttt ggactcctgg acacctgcgt ttaacacccg
7441 caggcagccg ctctttgcac acctccgtaa gaggggggag tcacaagctt agtgaaaagg
7501 tgaaaattta tttaggatga attgatttta cctttt
//