Typing tool
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Typing tool
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Complete norovirus genomes
| KY424342 | GII.6 | |
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| GII.P7 |
ORF1: 1..5060
ORF2: 5041..6684
ORF3: 6684..7460
LOCUS KY424342 7509 bp RNA linear VRL 19-APR-2018
DEFINITION Norovirus GII.6 isolate Hu/GII.6/BethesdaD7/2012/US nonstructural
polyprotein gene, partial cds; and major capsid protein VP1 and
minor capsid protein VP2 genes, complete cds.
ACCESSION KY424342
VERSION KY424342.1
KEYWORDS .
SOURCE Norovirus GII.6
ORGANISM Norovirus GII.6
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7509)
AUTHORS Parra,G.I., Squires,R.B., Karangwa,C.K., Johnson,J.A., Lepore,C.J.,
Sosnovtsev,S.V. and Green,K.Y.
TITLE Static and Evolving Norovirus Genotypes: Implications for
Epidemiology and Immunity
JOURNAL PLoS Pathog. 13 (1), e1006136 (2017)
PUBMED 28103318
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7509)
AUTHORS Parra,G.I., Squires,R.B., Karangwa,C.K., Johnson,J.A., Lepore,C.,
Sosnovtsev,S.S. and Green,K.Y.
TITLE Direct Submission
JOURNAL Submitted (03-JAN-2017) LID, NIAID, NIH, 50 South Drive, B50/R6316,
Bethesda, MD 20892, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Bowtie v. 2; Sequencher v. 5
Sequencing Technology :: Sanger dideoxy sequencing; IonTorrent
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7509
/organism="Norovirus GII.6"
/mol_type="genomic RNA"
/isolate="Hu/GII.6/BethesdaD7/2012/US"
/host="Homo sapiens"
/db_xref="taxon:499193"
/country="USA"
/collection_date="Dec-2012"
/note="genotype: GII.6"
CDS <1..5060
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="APU54789.1"
/translation="FGSQNSVNDSINTAPSKEEVGAFSNIKVGFKKMLGAVPKGTKAP
SSDQHCPSVKIGAKTLIVPPEPPNGEDTVQFDAKSETVRGLPDLTTVQNEHENTPYTV
PPLSEREHRPATEPLPGTILEMWDGEFYHYSVYVSGGKALGVHKPPAAISLATIELTP
ISLYWRPVYTPNYLVCPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLSRRSIS
RTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLLH
LLASCDWTFAGIVETVILMAELFNIFWTPPDVSSFIASLIGDFELQGPEDLAVELVPV
VMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAEM
ETLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDIV
GTINAILARIAAARSLLHKAKEEMFSRTRPVVVMISGRPGIGKTHMARHLAKSIANTM
SGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQELADTCPVTLNCDR
IENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEIEKVKRDFPGQ
PDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHERR
DEFQLQGNDLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGTALKSVKTLEDLKVALR
DVKFNECEIIYRNSKYRVSSNGKGSVSVDKVEDQTSQTANEVGAALLRLRQARARYYV
SCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTETQETGESEKEVTQGRWEIEPK
DTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDRY
YEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTGSDIRKRRPDDFQ
PKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKGI
KELFGVEIKQIQIHKSGEFCRFRFPRPIRPDVAGLVLEEGAPEGTVCSILVKRPTGEM
IPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDIV
VAGVHTAAARGGNTVICATQGQDGEAVLEGNENLGTYCGAPILGPGKAPKLSTKTKFW
RSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRGKPPRPAVLEEAK
KTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHVRKNDHWNGESFTGPLADQAS
KANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGLM
DSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRSILSAAMEV
MVRFSAEPELAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWNSIAHWILTLS
AMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLVPTRPDKTEG
PLAITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHSQ
RATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLSTW
EGDRNLAPEGVNEDGVE"
CDS 5041..6684
/codon_start=1
/product="major capsid protein VP1"
/protein_id="APU54790.1"
/translation="MKMASNDAAPSNDGAANLVPEATNEVMALEPVVGASIAAPVVGQ
QNIIDPWIRENFVQAPQGEFTVSPRNSPGEMLLNLELGPELNPYLSHLSRMYNGYAGG
MQVQVVLAGNAFTAGKIIFAAVPPHFPVENISAAQITMCPHVIVDVRQLEPVLLPLPD
IRNRFFHYNQENTPRMRLVAMLYTPLRANSGEDVFTVSCRVLTRPAPDFEFTFLVPPT
VESKTKPFTLPILTLGELSNSRFPAPIDMLYTDPNEAIVVQPQNGRCTLDGTLQGTTQ
LVPTQICSFRGTLISQTSRSADSTDSAPRVRNHPLHVQLKNLDGTPYDPTDEVPAVLG
AIDFKGTVFGVASQRNTTGNSIGATRAHEVHIDTTNPRYTPKLGSVLMYSESTDFDDG
QPTRFTPIGMGADDWHQWELPEYSGHLTLNMNLAPAVAPAFPGERILFFRSVVPSAGG
YGSGHIDCLIPQEWVQHFYQEAAPSQSAVALIRYVNPDTGRNIFEAKLHREGFITVAN
SGNNPIVVPPNGYFRFEAWVNQFYTLTPMGTGQGRRRVQ"
CDS 6684..7460
/codon_start=1
/product="minor capsid protein VP2"
/protein_id="APU54791.1"
/translation="MAGAFLAGLAGDAITSGVGSLINAGANAINQKVEYDFNKQLQLA
SFKHDKEMLQSQVLATKQLQQEMMNIRQGVLSAGGFSPTDAARGAVNAPMTKILDWNG
TRYFAPNSMKTTSYSGQFSSNPVHRQPTLPRSDPPKIKVNSDSASVYSSASTAPSQST
HSTALTAGSSSSRTTSSSAVASTLSRTSDWVRGQNERLSPFMDGALQTTFVTPPSSRA
SSYGSVSTVPKAVLDSWTPMFNTHRQPLFAHVRRRGESQI"
ORIGIN
1 cctttggcag ccaaaactct gtcaatgaca gcatcaacac cgccccttct aaagaagagg
61 ttggtgcatt ctccaacatc aaagttggtt ttaagaaaat gctgggtgcc gttcccaagg
121 ggaccaaagc acccagtagt gatcagcact gcccctcagt caagatcggg gccaagacat
181 taatagttcc ccctgagccc ccaaatggtg aagacaccgt gcagtttgat gcgaagtcgg
241 aaaccgtgcg cgggctacca gacttgacaa cggtgcagaa tgaacacgaa aacacaccat
301 acactgtccc cccattgagt gaaagggagc acagaccagc cactgaaccg cttcctggca
361 caatactgga gatgtgggat ggtgaattct accattactc tgtgtacgtc agcggtggca
421 aggccctagg ggttcacaag ccccctgcag cgataagcct cgcgacgata gagctcacac
481 ccatatctct ttattggagg cctgtttaca cccccaacta tctggtctgt ccagacacgt
541 tgaaaggcct tgctggtgag aagttcccct acacggcctt cagcaacaac tgttacaact
601 tctgttgctg ggtgcttgag ctcaatgaca cgtggcttag caggagaagc atctctagga
661 ctaccggctt cttcaaacca tatcagtctt ggaataggaa accccttcca accgttgatg
721 atggaaagat caaaaaggtg gccaacgcaa ttctctgcgc acttggatca ctgttttcaa
781 aaccaatcaa ggacctattg ggcaaactta aaccattgaa cttgctgcac ttgctcgcat
841 catgtgactg gacgtttgcg ggtatagtag agacagtcat cctaatggcg gaacttttca
901 acatcttttg gacaccgcca gatgtttcca gtttcatagc ctctctgata ggtgattttg
961 aattgcaagg gcctgaggac ctggctgtgg agcttgtccc cgtggtcatg ggtggcatag
1021 gaatggttct cggctttact gctgagaaga taggccgcat gctgtcgtcc gctgcatcaa
1081 cactacgggc atgcaaagac ttggggaatt atgcacttga catattgaaa ctggttatga
1141 agtggttctt tccaaagaaa gaagagaaag ccgagatgga aaccctaagg gcgattgaag
1201 atgccgtcct ggacatggaa gctataggaa ataaccatct cacaaccctc ctcaaggaca
1261 aggatagcct cacggctttc atgaagactc tagatctaga agaggagaag gcaaggaaac
1321 tgtccaccaa atcatcctcg ccagacatcg tcggcactat taatgccata ctggccagaa
1381 tagctgctgc caggtctctc ttgcacaagg ctaaagaaga gatgtttagc aggaccagac
1441 ccgtggttgt catgatctcg ggtagacctg gcattggcaa aacccacatg gcaagacact
1501 tggctaagag tatcgccaac accatgagcg gcgaccagag agtagggctc gtcccacgca
1561 acggggtcga tcattgggac gcctacaggg gagagagggt ggtcttatgg gatgattatg
1621 gcatgggaaa ccctgtcaaa gatgccctaa cactgcaaga gttggccgac acctgcccag
1681 taactctaaa ctgtgatagg attgagaaca aggggaaaat gtttgacagt gatgtcatca
1741 taatcacgac caatttagtc aacccggcgc ccctcgatta tgtaaacttc gaggcttgct
1801 ccagaagggt cgactttctg gtctatgcag agtcaccaga aattgagaag gttaagagag
1861 atttccccgg ccaacctgac atgtggaagg accattttaa gccagacttc tcccacataa
1921 aattgactct agccccacag ggtggatttg acaagaatgg caacaccccg catggtaagg
1981 gcaccatgcg atccctaacc caggggtccc tgactgcaag ggttgcaggt cttgttcatg
2041 agaggagaga cgagtttcag ctccagggga acgaccttca aacatacaac tttgacacca
2101 acagggtctc tgcatttagg aagctggccg cagacaacaa gtatgggatc atggagacta
2161 tgagagtggg cacagcgctt aagagtgtca agaccttgga agatctgaaa gttgcactga
2221 gggatgtgaa gttcaatgag tgtgagataa tttacagaaa ctccaaatac cgagtctctt
2281 ctaatggtaa aggttctgtc tctgttgaca aagttgagga ccaaacatcc cagactgcaa
2341 acgaagtggg tgcagcactc cttaggctca ggcaggcaag agccagatac tatgtcagct
2401 gcttccaaga tctcgtttac actctaatac aggtcgccgg agcatcattc gttgtcaaca
2461 ggatctctaa aaggttctgt tgggagagat gggtcaaacc aaccgagacc caggaaacgg
2521 gtgaatccga aaaggaagtg acccaaggca gatgggagat tgaacccaag gacacagaac
2581 cagaaggtaa gaagggtaag aacaagaaag gaagaggcaa gaaacacaca gctttctcca
2641 gcaaaggcct gagtgatgag gagtatgacg agttcaagag aatcagagaa gaaaggaacg
2701 gaaaatactc cattgaggaa tacctgcaag accgggatcg ttactatgag gaagtggcag
2761 ttgcccgggc gacagaggag gacttctgtg aagaggagga ggccaagata agacaaagaa
2821 tctttcgccc cacaaagaaa cagaggaagg aagaaagggg ggtgcttggt ttggtcactg
2881 gctcagacat caggaagaga agaccagacg attttcaacc gaagggaaac ctgtgggcag
2941 acgacaccag gagtgtggac tacaacgaga gacttgattt cgaggctccc ccgagtgtct
3001 ggtcaagaat agtcccattg ggcactggct ggggcttctg ggtctcatca aacctcctga
3061 tcacaacaac acacgtcctg cctaagggga ttaaggaact ttttggagtt gaaatcaaac
3121 agattcaaat tcataagtct ggagagttct gcaggttcag attcccgaga ccaattagac
3181 cagatgtcgc agggctcgtg ttggaggaag gcgctccaga aggcactgtc tgctccatac
3241 tcgtaaagag acctacaggt gagatgatcc ccctggcagt gaggatgggc acgcatgcat
3301 ccatgaaaat acagggtagg accgtcggtg gccagatggg aatgctcctc acaggggcaa
3361 acgcgaagaa catggacctt ggcaccggtc ctggtgactg cggttgccct tacatctaca
3421 aacgtggcaa tgatatagtt gtcgcgggtg tccacaccgc agcagcccgg ggaggcaaca
3481 ctgtcatatg tgccactcaa gggcaagatg gggaagcagt ccttgagggg aatgagaacc
3541 ttggcaccta ctgcggtgcc ccaatcttgg gtccaggcaa ggcgcccaaa cttagcacga
3601 agaccaagtt ctggcgctca tcaccagacg ctttgccacc aggcacttat gagcctgcct
3661 acttgggagg taaggacccc agagtggaaa aaggaccatc cctgcagcaa gtcatgaggg
3721 accagctaaa acctttcaca gaacccaggg gcaagccacc tagacctgca gtcttagaag
3781 aggccaaaaa gacagtgatg aatgttctag agcaaaccat tgaccctgcc aagccgtgga
3841 cctattccca agcgtgtgcc tcactggaca agaccacttc cagtggtagc ccccatcatg
3901 tcaggaaaaa tgaccattgg aatggggaat ccttcactgg cccccttgca gaccaagcat
3961 ccaaagccaa cctcatgtac gagcaggcca aacatgtgca gcccgtgtac acggccgcac
4021 ttaaagatga actagttaaa actgacaaga tctacaagaa gataaagaaa aggctcttat
4081 gggggtcgga tcttggtaca atgatcaggt gtgccagggc ctttggcggt ctcatggata
4141 gcatgaaggc aagttgcata gccctcccat gtagggtagg aatgaacatg aatgaagatg
4201 gtcccatcat atttgacaaa cattctaagt ataggtatca ttatgatgct gactattcca
4261 ggtgggactc aacccagcaa aggagcattc tctcggccgc tatggaagtg atggtgcggt
4321 tctctgccga gccagagctg gcacaagtgg ttgcagagga cctcctggca cccagccaac
4381 tagatgttgg cgatttcgtc atctcagtcc aggagggtct gccatcaggg gttccatgca
4441 catcacaatg gaattcaata gcacactgga tcctaacctt gagtgcaatg gcagaagtgt
4501 cgggtctctc accagatgtt gttcaagccc actcctgttt ctcattctac ggtgatgatg
4561 agatcgtcag cacagacatc aaccttgatc ccatgaagtt gacacagaaa cttagagagt
4621 atggcttggt ccccactcga cctgacaaaa ctgagggtcc cctcgcaata actgaagatc
4681 tcaccggcct aacgttcctg cgcaggtcaa ttgcacggga cccagctggg tggtttggaa
4741 aattagacca agactcaatc ctcagacagt tgtactggac aaggggcccc aatcatgaga
4801 acccatatga gagcatggtc cctcattccc agcgggccac acagcttatg gcccttctcg
4861 gtgaggcttc actgcatggt ccccagtttt acaagaaagt tagcaagatg gtcattaatg
4921 agatcaaaag tggtggtctg gaattctatg tgcccagaca agaggccatg ttcagatgga
4981 tgagattctc tgacctcagc acatgggagg gcgatcgcaa tcttgctccc gagggtgtga
5041 atgaagatgg cgtcgaatga cgctgctcca tcgaatgatg gtgctgccaa cctcgtacca
5101 gaggccacca atgaggttat ggcacttgag ccggtggtgg gagcctcaat cgctgctcct
5161 gtcgtcggcc aacaaaatat aattgacccc tggattagag aaaattttgt tcaggcacca
5221 cagggtgagt tcactgtttc accaaggaac tcacctggtg agatgcttct aaatcttgaa
5281 ttaggccctg agctcaaccc ttatctgagt catttgtccc gcatgtataa cggctatgct
5341 ggtggtatgc aggttcaggt ggtcctagct gggaatgcgt tcacagctgg taaaatcatc
5401 tttgccgccg tcccaccaca tttccctgtt gagaatatta gtgcagccca aattacaatg
5461 tgcccccatg taattgttga tgtaagacag cttgagccag tgcttttgcc cctccctgac
5521 ataaggaata gattctttca ttataatcag gaaaacaccc cccggatgag acttgtggct
5581 atgttgtaca caccccttag agcaaattct ggtgaggatg tgtttacggt gtcttgcagg
5641 gttctgaccc gccctgcccc cgactttgag ttcacgtttt tggtgccacc aactgtggag
5701 tcaaagacta agccctttac actccctatt ctgactcttg gagagctgtc caactccaga
5761 ttccccgctc caatagacat gttgtacact gaccccaatg aggcaattgt ggtgcaacca
5821 caaaatggca ggtgcactct agatggaaca cttcaaggga ccacccaact ggtacccacc
5881 caaatttgct ccttcagggg cacgctaatt agccagacgt cgaggtctgc agattcaaca
5941 gattcagccc cacgggtgag gaaccaccct ctccacgttc agctgaagaa cctcgatggg
6001 acaccatatg acccaacaga tgaagtgcca gcagttttgg gtgccataga tttcaaagga
6061 actgtgtttg gggtcgctag tcaaagaaac accacaggga actctatagg agcaacccgc
6121 gcccatgaag tgcacataga taccacaaac cctagatata ccccaaagct tggctctgtg
6181 ttgatgtatt ctgaatctac tgattttgat gatggacaac ccacccgctt tacccccatt
6241 ggcatgggag ccgatgattg gcaccaatgg gaattgcccg aatattctgg tcacctcact
6301 cttaacatga atttggcccc cgcagttgcc cctgctttcc ctggtgagcg catcctcttc
6361 ttcagatcag tggtgccgtc tgctggtggc tatggatcag gtcacataga ttgcctcatc
6421 ccacaggaat gggttcagca tttctaccag gaggccgctc catcacagtc tgcggtggct
6481 cttatcagat atgtcaaccc tgacactgga agaaacatct ttgaggcaaa actgcataga
6541 gaagggttca tcactgtggc aaattctgga aacaacccta tagttgtgcc cccaaatggt
6601 tacttcaggt ttgaggcctg ggtcaaccaa ttctatacac tcacccccat gggaactgga
6661 caggggcgca gaagagttca ataatggcag gagctttctt agctggattg gcaggtgacg
6721 ccataacaag tggtgtcggg tccctaatca atgctggggc caatgcaatt aaccaaaagg
6781 tagagtatga ttttaataaa cagctccaat tggcatcctt caaacatgac aaagagatgt
6841 tgcagtcaca agtactggcc actaaacagc tccagcagga aatgatgaac ataaggcaag
6901 gggtcttgtc cgctggcggc ttttccccta cagatgccgc gagaggtgct gtgaacgcgc
6961 cgatgacaaa aatcttggat tggaatggaa caaggtactt cgccccaaat agtatgaaga
7021 caaccagtta ttcgggccag ttttccagca accctgtgca taggcaaccc actttacccc
7081 gttctgaccc cccaaaaatc aaggttaata gtgattctgc tagtgtgtat agttctgcat
7141 ctactgctcc ttcacaatca acccactcaa cggctttgac tgcggggtct agctcatcta
7201 ggacaacatc ctcttctgca gtagcttcca ctctatctag gactagtgat tgggtgagag
7261 gacaaaatga gaggcttagc ccgtttatgg atggtgctct ccaaacaact tttgtcacac
7321 caccatcgag cagggcttca tcatatgggt cggtctcaac cgttcccaaa gctgttttgg
7381 actcctggac tcctatgttc aatacccata ggcagcctct cttcgctcat gtgcgcaggc
7441 gaggggagtc acagatttag tgaaaagatt gattaggttt tctttctttc ttcttttcct
7501 tttctttct
//