Typing tool
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Typing tool
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Complete norovirus genomes
| KY424329 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 1..5069
ORF2: 5050..6672
ORF3: 6672..7478
LOCUS KY424329 7529 bp RNA linear VRL 19-APR-2018
DEFINITION Norovirus GII.4 isolate Hu/GII.4/RockvilleD7/2012/US nonstructural
polyprotein gene, partial cds; and major capsid protein VP1 and
minor capsid protein VP2 genes, complete cds.
ACCESSION KY424329
VERSION KY424329.1
KEYWORDS .
SOURCE Norovirus GII.4
ORGANISM Norovirus GII.4
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7529)
AUTHORS Parra,G.I., Squires,R.B., Karangwa,C.K., Johnson,J.A., Lepore,C.J.,
Sosnovtsev,S.V. and Green,K.Y.
TITLE Static and Evolving Norovirus Genotypes: Implications for
Epidemiology and Immunity
JOURNAL PLoS Pathog. 13 (1), e1006136 (2017)
PUBMED 28103318
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7529)
AUTHORS Parra,G.I., Squires,R.B., Karangwa,C.K., Johnson,J.A., Lepore,C.,
Sosnovtsev,S.S. and Green,K.Y.
TITLE Direct Submission
JOURNAL Submitted (03-JAN-2017) LID, NIAID, NIH, 50 South Drive, B50/R6316,
Bethesda, MD 20892, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Bowtie v. 2; Sequencher v. 5
Sequencing Technology :: Sanger dideoxy sequencing; IonTorrent
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7529
/organism="Norovirus GII.4"
/mol_type="genomic RNA"
/isolate="Hu/GII.4/RockvilleD7/2012/US"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:489821"
/geo_loc_name="USA"
/collection_date="Jan-2012"
/note="genotype: GII.4"
CDS <1..5069
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="APU54750.1"
/translation="AVANSNNDIAKSSSDGVFSNMAVTFKRALGARPKQPPPKEIPPR
PPRPPTPELVKKIPPPPPNGEDELVVSYSAKDGVSGLPELTTVRQPEETNTAFSVPPL
NQRESRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHRPPAAISLAKVELTPLSL
FWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDSWLSRRMIQRTT
GFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGKLKPLNILNILA
TCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPIVMG
GIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAMV
RSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSASPDIVGTI
NSLLARIAAARSLVHRAKEELSSRPRPVVVMISGKPGIGKTHLARELAKKIAASLTGD
QRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLTLNCDRIEN
KGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPDM
WKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERLDEY
ELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDVKTMPDLKQALKNIA
IKKCQIVYNGSTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLRCARIRYYVKCV
QEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEMANKDGCLKPKDDEEFVV
SSDDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIRDERNGKYSIEEYLQDR
DRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLVTGSEIRKRNPE
DFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVSPSLFITSTHVIP
QGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTVATLLIKRPT
GELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGN
DYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILGPGSAPKLSTKT
KFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQIMRDQLKPFTEPRGKPPRPNVLE
AAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKNDCWNGESFTGKLAD
QASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKIKKRLLWGSDLATMIRCARAFG
GLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQRDVLAAA
LEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISISEGLPSGVPCTSQWNSIAHWLL
TLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDK
TEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPNHEDPFETMIP
HSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEPMFRWMRFSDL
STWEGDRNLAPSFVNEDGVE"
CDS 5050..6672
/codon_start=1
/product="major capsid protein VP1"
/protein_id="APU54751.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICNFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRVV"
CDS 6672..7478
/codon_start=1
/product="minor capsid protein VP2"
/protein_id="APU54752.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANLRDAVPAHGSSSKSS
NFSTATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 ccgctgttgc caacagcaac aacgacatcg caaaatcttc aagtgacggt gtgttttcta
61 acatggctgt cactttcaaa cgggccctcg gggcgcggcc taaacagccg cccccgaagg
121 aaataccacc cagacccccg cgaccaccca caccagaatt ggtcaaaaag atccctcctc
181 ccccacccaa cggggaggat gaactagtgg tctcctacag cgccaaagat ggcgtttccg
241 gactgcctga gctcaccact gtcagacaac cggaagaaac caacacggcg ttcagcgtcc
301 ccccactcaa ccaaagggag agcagggacg ccaaggagcc actaactgga acaattattg
361 aaatgtggga tggagaaatc taccattacg gcctgtacgt ggaacgaggt cttatacttg
421 gtgtgcacag gccaccggca gccatcagcc ttgccaaggt cgagctaaca ccgctctctt
481 tgttctggag acctgtatac accccccagt atctcatctc tccagacact cttaggagac
541 tacatggaga gtcattcccc tacactgcat ttgacaacaa ttgctacgcc ttttgttgtt
601 gggtattaga cctaaacgac tcatggctaa gcaggagaat gattcagaga acaacaggtt
661 tcttcagacc gtaccaggat tggaacagga aacccctccc cactatggat gattccaaat
721 taaagaaggt agccaacata ttcttgtgca ctttgtcttc actattcacc agacccatta
781 aggacataat agggaagttg aaacctctta acatccttaa cattctggct acatgtgatt
841 ggaccttcgc aggcatagtg gaatccttaa tactcttggc agaactcttt ggagttttct
901 ggacaccccc agatgtgtct gcgatgatcg cccccttgct aggtgattat gaactgcaag
961 gacctgagga ccttgcagtg gaactggtcc caatagtgat gggggggata ggtttggtgc
1021 taggatttac caaagagaaa attggaaaga tgctatcatc cgctgcatcc actttaagag
1081 cttgtaaaga ccttggtgca tacggactgg aaatcttaaa actggtcatg aagtggttct
1141 tcccaaagaa agaggaagca aatgaactgg ctatggtgag gtccatcgag gatgcagtgc
1201 tagacctcga ggcaattgaa aacaaccaca tgaccaccct actcaaagac aaagacagct
1261 tggcaaccta catgagaacc ctagaccttg aggaggagaa agccagaaaa ctctcaacca
1321 aatctgcttc acccgatatt gtgggcacaa tcaactctct tctggcaaga atcgctgctg
1381 cacgctccct agtgcatcgg gcgaaagaag agctctccag caggccgaga cctgtcgttg
1441 tgatgatatc gggaaaacca gggataggga aaactcacct tgccagggag ctggccaaga
1501 agatcgcggc ctccctcaca ggggaccagc gtgtgggtct tatcccgcgc aatggtgtcg
1561 accactggga cgcatacaag ggtgaaagag ttgtcctatg ggacgactat ggaatgagca
1621 accccatcca tgatgccctc aggttgcagg agcttgctga cacttgcccc ctcacgctaa
1681 attgtgatag aattgagaac aaagggaaag tctttgacag tgatgccata attatcacca
1741 ccaatctggc caacccagca ccactggatt acgtcaactt tgaagcgtgc tcgagacgca
1801 ttgacttcct cgtgtacgca gaagcccctg aggtggagaa ggcaaagcgc gacttcccag
1861 gtcaacctga catgtggaag aacgctttca gtcctgactt ctcacacata aaactatcat
1921 tggctccaca gggtggtttt gacaagaacg gcaacacccc acatggaaaa ggggtcatga
1981 agaccctcac cactggctcc ctcatcgccc gagcatcagg gttactccat gagaggctag
2041 atgaatatga actgcaaggc ccagccctca ccactttcaa ctttgatcgt aacaagatac
2101 ttgcttttag acagcttgct gctgaaaaca agtatgggct gatggacaca atgagagttg
2161 gaaaacagct caaggatgtc aagaccatgc cagacctcaa acaagcactc aagaatatcg
2221 cgatcaagaa gtgccaaata gtgtacaatg gtagcaccta cacacttgag gccgatggca
2281 agggtagtgt gaaagttgac aaagtgcaaa gcgccactgt gcagaccaac aatgaactag
2341 ccggtgccct acaccaccta aggtgcgcca gaatcagata ctatgttaag tgcgtccagg
2401 aggcactgta ttccatcatc caaatcgctg gggctgcatt cgtcaccacg cgcatcgcta
2461 agcgcatgaa tatacagaat ctctggtcca agccacaggt ggaagacaca gaagagatgg
2521 ccaacaaaga tggttgccta aaacccaaag atgatgaaga gtttgtcgtc tcatccgacg
2581 acatcaaaac tgagggtaag aaagggaaga acaagtccgg ccgtggcaag aagcacacag
2641 ccttttcaag caaaggactc agtgatgagg agtacgatga gtacaagaga atcagagacg
2701 aaaggaatgg taagtattcc atagaagagt accttcagga cagagacagg tactacgagg
2761 aggtggccat tgccagggca accgaagagg acttctgtga agaagaagag gccaaaatcc
2821 ggcagaggat tttcagacca acaaggaaac aacgcaaaga agagagggcc tctctcggct
2881 tggttacagg ctctgaaatc aggaagagaa acccagaaga tttcaaaccc aagggaaagc
2941 tgtgggctga tgatgacaga agtgttgatt acaatgagaa actcaacttt gaggccccac
3001 caagcatctg gtcgcggata gtcaactttg gttcaggttg gggcttctgg gtctccccca
3061 gtctgtttat aacatcaacc catgtcatac cccaaggtgc aaaagagttc ttcggagtcc
3121 ctatcaagca aatccagata cacaaatcag gtgaattttg ccgattgaga ttcccaaaac
3181 caatcagaac tgatgtgacg ggcatgattc tagaagaagg tgcgcccgaa gggaccgtgg
3241 ccacactgct catcaagaga ccaactggag agctcatgcc tctggcagcc agaatgggga
3301 cccatgcaac catgaaaatt caggggcgca cagttggagg gcaaatgggt atgctcctga
3361 caggatccaa cgccaagagt atggacctag gcacaacacc aggcgactgc ggctgcccct
3421 acatttacaa gagggggaat gactacgtgg tcataggagt ccatacggcc gctgctcgtg
3481 gaggaaacac tgtcatatgt gccacccagg ggagtgaggg agaagccaca cttgaagggg
3541 gtgacagtaa agggacatac tgtggtgcac caatcttggg cccagggagc gctccgaagc
3601 tcagtaccaa gactaagttt tggagatcat ccacaacacc actcccacct ggcacctacg
3661 aaccagccta cctcggtggc aaagacccca gagtcaaagg tggcccttca ttgcaacaaa
3721 ttatgaggga ccagctaaag ccattcacag aacccagagg caaaccacca agaccaaatg
3781 tgttggaagc tgccaagaaa accatcatca atgtccttga gcaaacaatc gacccacccc
3841 aaaaatggtc attcgcgcaa gcttgcgcat cccttgacaa aaccacctcc agcggccacc
3901 cgcaccacat gcggaaaaac gattgttgga atggggagtc cttcacagga aaattggctg
3961 atcaggcctc caaggccaac ctaatgtttg aagagggaaa gaacatgact ccagtctaca
4021 caggtgcact taaagatgag ctggtaaaga ccgataaagt ttatggtaag atcaagaaga
4081 gacttctgtg gggttcagat ctggcgacca tgatacggtg cgcccgagct tttggaggcc
4141 ttatggatga actcaaggca cactgtgtca cacttcctgt cagagttggt atgaacatga
4201 atgaggatgg ccccatcatc tttgagaagc actccagata tagatatcac tatgatgctg
4261 attattcccg gtgggactca acacaacaaa gggatgtgct agcagcagca ctggaaatca
4321 tggttaagtt ctctccggaa ccacacctgg cccagatagt tgcagaagac ctcctttccc
4381 ctagcgtaat ggatgtaggt gactttcaaa tatcaataag tgagggtctc ccctctgggg
4441 taccttgtac ctcccagtgg aattccatcg cccactggct cctcactctt tgtgcactct
4501 ctgaagtcac ggacctgtcc cctgacatca ttcaggccaa ctctcttttc tccttctatg
4561 gtgatgatga gattgtaagc acagacataa agttggaccc agagaagctg acagcaaaac
4621 tcaaggagta cgggctgaaa ccaacccgcc ccgacaaaac tgaaggaccc cttgttatct
4681 ctgaagacct ggatggcctg acattcctcc ggagaactgt gacccgtgat ccagctggct
4741 ggtttggaaa attggaacaa agttcaattc tcaggcaaat gtactggacc aggggtccca
4801 accatgaaga tccatttgaa acaatgatac cacactccca aagacccata caattgatgt
4861 ccttactggg cgaggctgca ctccacggcc cggcatttta tagcaaaatt agcaaattag
4921 tcattgcaga gttgaaggaa ggtggcatgg atttttacgt gcccagacaa gagccaatgt
4981 tcagatggat gagattctca gatctgagca cgtgggaggg cgatcgcaat ctggctccca
5041 gttttgtgaa tgaagatggc gtcgagtgac gccaacccat ctgatgggtc cgcagccaac
5101 ctcgtcccag aggtcaacaa tgaggttatg gctctggagc ccgttgttgg tgccgccatt
5161 gcggcacctg tagcgggcca acaaaatgta attgacccct ggattagaaa caattttgta
5221 caagcccctg gtggagagtt tacagtatcc cctagaaacg ctccaggtga aatactatgg
5281 agcgcgccct taggccctga tctaaatccc tacctatccc atttggccag aatgtacaac
5341 ggttatgcag gtggttttga agtgcaggta attctcgcgg ggaacgcgtt caccgccggg
5401 aagatcatat ttgcagcagt cccaccaaat tttccaactg aaggcttaag ccccagccag
5461 gtcactatgt tcccccatat aatagtagat gttaggcaac tagaacctgt gttgattccc
5521 ttacccgatg ttaggaataa tttctatcat tacaatcaat caaatgaccc caccattaag
5581 ttgatagcaa tgttgtatac accacttagg gctaataatg ctggggacga tgtcttcaca
5641 gtttcttgcc gagttctcac gagaccatcc cccgattttg atttcatatt tttagtgcca
5701 cccacagttg agtcaagaac taaaccattc tctgtcccag ttttaactgt tgaggagatg
5761 accaattcaa gattccccat tcctttggaa aagttgttta cgggtcccag cagtgccttt
5821 gttgttcaac cacaaaacgg caggtgcacg actgatggcg tgctcctagg caccacccaa
5881 ctgtctcctg tcaacatctg caacttcaga ggggatgtca cccatatcac aggtagtcgt
5941 aactacacaa tgaatttggc ttctcaaaat tggaacaatt atgacccaac agaagaaatc
6001 ccagcccctc taggaactcc agattttgtg gggaagattc aaggcatgct cacccaaacc
6061 acaaggacag atggctcaac acgcggccac aaagctacag tgtacactgg gagcgccgac
6121 tttgctccaa aactgggtag agttcaattt gaaactgaca cagaccatga ttttgaagct
6181 aaccaaaaca caaagttcac cccagtcggt gtcatccaag atggtagcac cacccaccga
6241 aatgaacccc aacagtgggt gctcccaagt tactcaggca gaaatactca taatgtgcat
6301 ctggcccccg ctgtagcccc cacttttccg ggtgagcaac ttctcttctt tagatccacc
6361 atgcccggat gcagcgggta ccccaacatg gatttggact gtctgctccc ccaggaatgg
6421 gtgcagtact tctaccaaga ggcagcccca gcacaatctg acgtggctct gctaagattt
6481 gtgaatccag acacaggtag ggttttgttt gagtgtaagc ttcataaatc aggctatgtt
6541 acagtggctc acactggcca acatgatttg gttatccccc ccaatggtta ttttaggttc
6601 gattcctggg tcaaccaatt ctacacgctt gcccccatgg gaaatggaac ggggcgtaga
6661 cgtgtagtat aatggctgga gctttctttg ctggattggc atctgatgtc cttggctctg
6721 gacttggttc tcttatcaat gctggggctg gggccatcaa ccaaaaagtt gagtttgaaa
6781 ataacagaaa attgcaacaa gcatccttcc aatttagcag caatctacaa caggcttcct
6841 ttcaacatga caaagagatg ctccaagcac aaattgaggc caccaaaaag ctacaacagg
6901 aaatgatgaa agtcaagcag gcaatgctcc tagagggtgg gttctctgag acagatgcag
6961 cccgcggggc aatcaacgcc cccatgacaa aagctttgga ctggagcggg acaaggtact
7021 gggctcccga tgctaggact acaacataca atgcaggccg cttttccacc cctcaaccat
7081 cgggggcact gccaggaaga gctaatctta gggatgctgt ccctgctcat ggttcctcca
7141 gcaaatcttc taacttttct actgctactt ctgtgtactc aaatcaaact acttcaacga
7201 gacttggttc tacagctggt tctggtacca gtgtctcgag cctcccgtca actgcaagga
7261 ctaggagctg ggttgaggat caaagtagga atttgtcacc tttcatgagg ggggcccaca
7321 acatatcgtt tgtcacccca ccatctagca gatcctctag ccaaggcaca gtctcaaccg
7381 tgcctaaaga ggttttggac tcctggactg gcgctttcaa cacgcgcagg cagcctctct
7441 tcgctcacat tcgtaagcga ggggagtcac gggtgtaatg tgaaaagaca aaattgatta
7501 cctttctttt tctttcttta gtgtctttt
//