Human calicivirus
Typing tool

Complete norovirus genomes

KY341923  GII.4 Sydney
 GII.P31

Length: 3,207 | 3 CDS 

ORF1: 1..798
ORF2: 779..2401
ORF3: 2401..3207

LOCUS       KY341923                3207 bp    RNA     linear   VRL 12-MAR-2017
DEFINITION  Norovirus GII.4 strain Hu/GII.4/13164/2015/HUN nonstructural
            polyprotein (ORF1) gene, partial cds; and capsid protein VP1 (VP1)
            and capsid protein VP2 (VP2) genes, complete cds.
ACCESSION   KY341923
VERSION     KY341923.1
KEYWORDS    .
SOURCE      Norovirus GII.4
  ORGANISM  Norovirus GII.4
            Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
            Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE   1  (bases 1 to 3207)
  AUTHORS   Boros,A., Pankovics,P., Komives,S., Liptai,Z., Dobner,S.,
            Ujhelyi,E., Varallyay,G., Zsidegh,P., Bolba,N. and Reuter,G.
  TITLE     Co-infection with coxsackievirus A5 and norovirus GII.4 could have
            been the trigger of the first episode of severe acute
            encephalopathy in a six-year-old child with the intermittent form
            of maple syrup urine disease (MSUD)
  JOURNAL   Arch. Virol. (2017) In press
   PUBMED   28243803
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 3207)
  AUTHORS   Bolba,N. and Boros,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-DEC-2016) Regional Laboratory of Virology, ANTSZ,
            Baranya County Institute of State Public Health Service, Szabadsag
            u. 7, Pecs H-7623, Hungary
COMMENT     ##Assembly-Data-START##
            Sequencing Technology :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..3207
                     /organism="Norovirus GII.4"
                     /mol_type="genomic RNA"
                     /strain="Hu/GII.4/13164/2015/HUN"
                     /isolation_source="stool"
                     /host="Homo sapiens"
                     /db_xref="taxon:489821"
                     /geo_loc_name="Hungary"
                     /collection_date="2015"
     gene            <1..798
                     /gene="ORF1"
     CDS             <1..798
                     /gene="ORF1"
                     /note="RdRp"
                     /codon_start=1
                     /product="nonstructural polyprotein"
                     /protein_id="AQX33493.1"
                     /translation="WDSTQQRDVLAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGD
                     FQISISEGLPSGVPCTSQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIV
                     STDIKLDPEKLTAKLKEYGLKPTRPDKTDGPLVISEDLDGLTFLRRTVTRDPAGWFGK
                     LEQSSILRQMYWTRGPNHEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVI
                     AELKEGGMDFYVPRQEPMFRWMTFSDLSTWEGDRNLAPSFVNEDGVE"
     gene            779..2401
                     /gene="VP1"
                     /note="ORF2"
     CDS             779..2401
                     /gene="VP1"
                     /codon_start=1
                     /product="capsid protein VP1"
                     /protein_id="AQX33494.1"
                     /translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
                     QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
                     FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
                     VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
                     TVESRTKPFSFPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
                     QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
                     TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
                     STTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
                     CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
                     IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
     gene            2401..3207
                     /gene="VP2"
                     /note="ORF3"
     CDS             2401..3207
                     /gene="VP2"
                     /codon_start=1
                     /product="capsid protein VP2"
                     /protein_id="AQX33495.1"
                     /translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
                     SFQFSSNIQQASFQHDKEMLQAQVEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
                     APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANLRDAVPARGSSSKSS
                     NSSTATSVNSNQTTSTRLGSSAGSGTSVSSFPSTARTRSWVEDQSRNLSPFMRGAHNI
                     SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN      
        1 tgggactcaa cacaacaaag ggatgtgcta gcagcagcac tagaaatcat ggttaagttc
       61 tctccagaac cacacctggc ccagatagtt gcagaagacc tcctttcccc tagcgtaatg
      121 gacgtaggtg actttcaaat atcaataagt gagggtctcc cctctggggt accttgtacc
      181 tcccagtgga attccatcgc ccactggctc ctcactctgt gtgcactctc agaagtcacg
      241 gacctgtccc ctgatatcat tcaggccaac tcccttttct ccttctatgg tgatgatgag
      301 attgtaagca cagacataaa gttggaccca gagaagctga cagcaaaact caaggagtac
      361 gggctgaaac caacccgccc cgacaaaact gatggacccc ttgtcatctc tgaagatctg
      421 gatggcctga cgttcctccg gagaactgtg acccgtgatc cagctggctg gtttggaaaa
      481 ttggaacaaa gttcaattct caggcaaatg tactggacca ggggtcccaa ccatgaagat
      541 ccatttgaaa caatgatacc acactctcaa agacccatac aattgatgtc cttgctgggc
      601 gaggctgcac tccacggccc ggcattctat agcaaaatta gcaaattagt cattgcagag
      661 ttgaaggaag gtggcatgga tttttacgtg cccagacaag agccaatgtt cagatggatg
      721 acattctcag atctgagcac gtgggagggc gatcgcaatc tggctcccag ttttgtgaat
      781 gaagatggcg tcgagtgacg ccaacccatc tgatgggtcc gcagccaacc tcgtcccaga
      841 ggtcaacaat gaggttatgg ctctggagcc cgttgttggt gccgccattg cggcacctgt
      901 agcgggccaa caaaatgtaa ttgacccctg gattagaaat aattttgtac aagcccctgg
      961 tggagagttt acagtatccc ctagaaacgc tccaggtgaa atactatgga gcgcgccctt
     1021 gggccctgat ttaaatccct acctatccca tttggccaga atgtacaatg gttatgcagg
     1081 tggctttgaa gtgcaggtaa ttctcgcggg gaatgcgttc accgccggga aggtcatatt
     1141 tgcagcagtc ccaccaaatt ttccaactga aggcttgagc cccagccagg tcactatgtt
     1201 cccccatata gtagtagatg ttaggcaact agaacctgtg ttgattccct tacccgatgt
     1261 taggaacaat ttctatcatt acaatcaatc aaatgaccct accattaaat tgatagcaat
     1321 gttgtataca ccacttaggg ctaataatgc tggggatgat gtcttcacag tttcttgccg
     1381 agtcctcacg agaccatccc ccgattttga tttcatattt ctagtgccac ccacagttga
     1441 gtcaagaact aaaccattct ctttcccagt tttaactgtt gaggagatga ccaattcaag
     1501 attccccatt cctttggaaa agttgttcac gggtcccagc agtgcctttg ttgtccaacc
     1561 acaaaacggt aggtgcacga ctgatggcgt gctcctaggc accacccaac tgtctcctgt
     1621 caacatctgc accttcagag gagatgtcac tcatatcaca ggtagtcgta actacacaat
     1681 gaatttggct tctcaaaatt ggaacaatta tgacccaaca gaagaaatcc cagcccctct
     1741 aggaactcca gattttgtgg ggaagatcca aggcgtgctc acccaaacca caaggacaga
     1801 tggctcaaca cgcggccaca aagctacagt gtatactggg agcgccgatt ttgctccaaa
     1861 actgggtaga gttcaatttg aaactgacac agaccatgat tttgaagcta accaaaacac
     1921 aaagttcacc ccagttggtg tcatccaaga tggtagcacc acccaccgaa acgaacccca
     1981 acagtgggtg ctcccaagtt actcaggcag aaatactcct aatgtgcatt tggcccccgc
     2041 tgtggccccc acttttccgg gtgagcaact tctcttcttc agatccacca tgcccggatg
     2101 cagcgggtac cccaacatgg atttggactg tctgctcccc caggaatggg tgcagtactt
     2161 ctaccaagag gcagccccag cacaatctga tgtggctctg ctaagatttg tgaatccaga
     2221 cacaggtagg gttttgtttg agtgtaagct tcataaatca ggctatgtta cagtggctca
     2281 cactggccaa catgatttgg ttatcccccc caatggttat tttaggtttg attcctgggt
     2341 aaaccagttt tacacgcttg cccccatggg aaatggaacg gggcgtagac gtgcactata
     2401 atggctggag ctttctttgc tggattggca tctgatgtcc ttggctctgg acttggttcc
     2461 cttatcaatg ctggggctgg ggccatcaac caaaaagttg agtttgaaaa taacagaaaa
     2521 ttgcaacaag catccttcca atttagcagc aatatacaac aagcttcctt tcaacatgac
     2581 aaagagatgc tccaagcaca agttgaggcc accaaaaagt tacaacagga aatgatgaaa
     2641 gttaagcagg caatgctcct agagggtggg ttctctgaga cagatgcagc ccgcggggca
     2701 atcaacgccc ctatgacaaa agctttggac tggagcggga caaggtactg ggctcccgat
     2761 gctaggacta caacatacaa tgcaggccgc ttttccaccc ctcaaccatc gggggcactg
     2821 ccaggaagag ctaatcttag ggatgctgtc cctgctcggg gttcctccag caagtcttct
     2881 aattcttcta ctgctacttc tgttaactca aatcaaacca cttcaacgag acttggttct
     2941 tcagctggtt ctggtaccag tgtctcgagc ttcccgtcaa ctgcaaggac taggagctgg
     3001 gttgaggatc aaagtaggaa tttgtcacct ttcatgaggg gggcccacaa catatcgttt
     3061 gtcaccccac catctagcag atcctctagc caaggcacag tctcaaccgt gcctaaagag
     3121 attttggact cctggactgg cgctttcaac acgcgcaggc agccactctt cgctcacatt
     3181 cgtaagcgag gggagtcacg ggcgtaa
//