Typing tool
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Typing tool
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Complete norovirus genomes
| KT326181 | GII.17 | |
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| GII.P17 |
ORF1: 1..5065
ORF2: 5046..6668
ORF3: 6668..7447
LOCUS KT326181 7518 bp RNA linear VRL 08-MAR-2016
DEFINITION Norovirus Hu/GII.17/CUHK-NS-649/HKG/2015 nonstructural polyprotein
(ORF1) gene, partial cds; and viral protein 1 (VP1) and viral
protein 2 (VP2) genes, complete cds.
ACCESSION KT326181
VERSION KT326181.1
KEYWORDS .
SOURCE Norovirus Hu/GII.17/CUHK-NS-649/HKG/2015
ORGANISM Norovirus Hu/GII.17/CUHK-NS-649/HKG/2015
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7518)
AUTHORS Chan,M.C., Lee,N., Hung,T.N., Kwok,K., Cheung,K., Tin,E.K.,
Lai,R.W., Nelson,E.A., Leung,T.F. and Chan,P.K.
TITLE Rapid emergence and predominance of a broadly recognizing and
fast-evolving norovirus GII.17 variant in late 2014
JOURNAL Nat Commun 6, 10061 (2015)
PUBMED 26625712
REFERENCE 2 (bases 1 to 7518)
AUTHORS Chan,M.C.W., Hung,T.T.N. and Chan,P.K.S.
TITLE Direct Submission
JOURNAL Submitted (22-JUL-2015) Department of Microbiology, The Chinese
University of Hong Kong, CUHK, Shatin 852, Hong Kong
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7518
/organism="Norovirus Hu/GII.17/CUHK-NS-649/HKG/2015"
/mol_type="genomic RNA"
/strain="Hu/GII.17/CUHK-NS-649/HKG/2015"
/isolate="CUHK-NS-649"
/host="Homo sapiens"
/db_xref="taxon:1760921"
/geo_loc_name="Hong Kong"
/collection_date="2015"
/note="genotype: GII.17"
gene <1..5065
/gene="ORF1"
CDS <1..5065
/gene="ORF1"
/note="contains RNA-dependent RNA polymerase; RdRp"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="ALP48595.1"
/translation="NNNNDKEKSSSDSLFANMSVTFKKALGARSKQPPPGETKQIQKP
PRPPTPELVKRIPPPPPNGEDEPGIVYKVGEGVSGLPDLTTVAQPDAQNTAYSVPPLS
QREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISLAKIEITPLSLY
WRVVYTPQYLIDPGTLKNLSGETFPYTAFDNNCYAFCCWVLDLNDSWLSRRMIQRTTG
FFKPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDIIGKLRPLNILNILAT
CDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDLAVELVPVVMGG
IGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFPKKEEANELAMVR
AIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSASPDIVGTIN
ALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELAKKVASTLSGDQ
RIGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLTLNCDRIENK
GKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDFPGQPDMW
KDHFRPDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARASGLLHERMDEFE
LQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTLDELKQAIKNISI
KKCQIVYNGCTYTMESDGRGKVVVEKVQNTTVQTNNELVGALHHLRSARIRYYVKCFQ
EAIYSLLQIAGAAFVTSRIVRRMNISNLWSKPPIEEGDEPEDRGGCPKPRDEDDLTID
SRDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRD
RYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDD
FKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFITSTHVIPK
GITGAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSILIKRTTG
ELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGND
LVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAPKLSTKTK
FWRSSNAPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPPNPNVLES
AKKTIINVLEQTIDPPQKWSYAQACASLDKTTSSGYPHHVRKNDYWSGESFTGKLADQ
ASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIRCARAFGG
LMDEFKANCITLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQRAVLEAAL
EIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPCTSQWNSIAHWLLT
LCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKT
EGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDPSETMIPH
AQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRWMRFSDLS
TWEGDRNLAPSFVNEDGVE"
gene 5046..6668
/gene="VP1"
CDS 5046..6668
/gene="VP1"
/codon_start=1
/product="viral protein 1"
/protein_id="ALP48596.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYSNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAQINQRDRWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
VSQRNVGNDAPGSTRAQQAWVSTYSPQFVPKLGSVNLRISDNDDFQFQPTKFTPVGVN
DDDDGHPFRQWELPNYSGELTLNMNLAPPVAPNFPGEQLLFFRSFVPCSGGYNQGIID
CLIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLV
VPANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6668..7447
/gene="VP2"
CDS 6668..7447
/gene="VP2"
/codon_start=1
/product="viral protein 2"
/protein_id="ALP48597.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVRATKQLQSEMIALKQGVLAAGGFSPTDAARGSIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMSSPNAPQSKPAKPRSLVPSSSSSSVYSMYTQST
HLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 aaacaacaac aacgacaagg aaaaatcttc aagtgacagc ttgtttgcta acatgtctgt
61 cacttttaag aaagccctcg gggcgcggtc taaacaaccg cccccgggag aaacaaaaca
121 aatacaaaaa ccaccaaggc caccgacacc ggaattggtg aagagaatac ctccaccccc
181 acccaatggc gaggacgaac cagggatagt gtacaaggtg ggagagggtg tgtctgggct
241 gcccgaccta acaactgtgg cacaacctga cgcacaaaac acagcttata gtgttccccc
301 acttagccag agagaagtcg gcgaagctaa agaaccgctg cctggctcca ttctggaaat
361 gtgggatggt gagatctacc actatgggct gtatgttgag cgggggcatg tgctcggagt
421 acacaaacca cctgctgcaa taagccttgc caaaattgaa ataacaccgc tgtctctcta
481 ctggagagtg gtctacactc cccagtattt gatagatcca ggaactctta agaacttgag
541 tggagagact ttcccataca cggcctttga caacaactgt tatgccttct gttgttgggt
601 cctagacctc aacgactcct ggcttagcag gagaatgatc caaagaacaa ctggattctt
661 caaaccttat caggattgga acagaaaacc cttaccaacc atggatgaac cgaaaatcaa
721 gaaggccgcg aatgctgtcc tatgcgctct ctcctcactc ttcactagac ccattaagga
781 catcattgga aagcttagac cactgaacat tcttaatata ttggcaacct gcgattggac
841 ttttgcaggc atagtggaat ccttgatcct tcttgctgaa ctctttgggg tgttctggac
901 acccccagat gtgtctgcga tgattgctcc cttactcggt gactacgaga tgcaaggccc
961 cgaagacctg gccgtggaac ttgtgcccgt ggtgatggga ggaataggtt tggtgttagg
1021 attcaccaaa gaaaagatcg gcaagatgct ttcatcagct gcgaccacac ttagggcctg
1081 caaggatcta ggatcttatg gattggagat actcaaattg gtcatgaagt ggttcttccc
1141 caagaaggag gaggctaacg aactagccat ggtgagggcc attgaggatg cagtcctgga
1201 tttggaggca atagaaaaca atcacatgac cacccttctc aaggataaag acagcctggc
1261 cacatacatg aggactcttg acttggaaga agagaaagca aggaaactgt caaccaaatc
1321 ggcgtcacct gacatcgtgg gtacaataaa tgcattattg gctaggatag cagccgccag
1381 gtcactggtc cacaaggcta aggaggagct ctcgagcaga cagagacctg ttgttgtaat
1441 gatatcaggt agaccaggta taggaaagac ccatctggcc agagagctag ccaagaaagt
1501 tgcgtcaaca ctgtcaggcg accaaaggat tggactggta cctaggaatg gcgtcgacca
1561 ttgggacgcc tacaagggag aaagggtggt tctgtgggat gattatggta tgagcaaccc
1621 tatacaggac gcactgaggc tccaagaatt ggctgacacc tgtcctctga ccctaaattg
1681 tgataggatt gaaaacaaag gaaaagtgtt cgacagtgat gccataatta taacaaccaa
1741 ccttgcaaac ccagcaccac tagactatgt caactttgag gcctgctcta gacgcataga
1801 cttcttggtg tatgcagacg cacctgacat tgagaaggct aagcgtgact tccctggcca
1861 accagatatg tggaaagacc atttcagacc agacttctca cacattaaac ttcagctggc
1921 accacaggga ggttttgaca aaaatggcaa caccccacat ggcaaaggtg tggtgaagtc
1981 cctgacgatt ggttctctga tcgccagggc ctccggcttg ctccacgaga gaatggatga
2041 atttgagctc caaggttctg acttgccaac cttcaatttt gaccgcaaca aagtcgccgc
2101 cttcagacaa ttagcagctg aaaacaaata tggtcttatg gacacactga gggtcggcaa
2161 ccaactgaaa agtgttaaga ccctggatga gctgaagcag gccataaaga acatcagtat
2221 caagaagtgt cagatagtgt ataatggatg cacctacacc atggaatctg atgggagggg
2281 caaggttgtg gttgaaaagg tacaaaacac aacagttcaa accaacaatg aacttgtagg
2341 ggcgctccac cacctgagat ctgcaaggat aagatactat gttaaatgtt tccaagaagc
2401 catttactct ctactccaaa ttgctggtgc agccttcgtc acctcacgca tcgtgaggcg
2461 catgaacata tcaaacctct ggtcgaagcc acccatcgag gagggtgatg agcctgaaga
2521 cagaggagga tgccccaagc ccagggatga agatgacctc actattgact ccagagacat
2581 taaagtggaa gggaagaagg gcaagaacaa gtctggccgg ggcaagaaac acacagcctt
2641 ctcttccaag ggcctcagtg atgaagagta cgatgagtac aagagaatca gagaggagag
2701 gaatggcaaa tactcaatag aggaatacct ccaagatagg gacagatact atgaagagct
2761 tgccattgct aaggccactg aggaggactt ctgtgaggag gaggagatca aaatccgcca
2821 gagaatcttc cgacccacca ggaagcagcg gaaagaggaa agggccacgc ttgggcttgt
2881 cacaggatca gaaatcagaa agaggaatcc agatgacttt aaaccaaaag gaaaattgtg
2941 ggctgatgac aacaggagcg tggattacaa tgagaggata gattttgagg ctcccccgag
3001 tgtttggtct aggatagtca actttggcac aggctgggga ttctgggttt ctccaagtct
3061 ctttataact tcaacacacg tcataccaaa aggaatcact ggggcctttg gagtgcccat
3121 aaaccaaatc caaattcaca aatctggaga attttgccgc ttgcggtttc caaagccaat
3181 tagaccagac gtgagtggga tgatcttgga agagggcgcc cctgaaggca ctgttgtgtc
3241 tattctcatc aaaaggacaa caggggagct gatgcctctt gcagtcagaa tggggactca
3301 tgccacaatg aaaatccaag gaagaacggt gggtggtcag atgggtatgc ttctcactgg
3361 ctcaaatgct aaaagcatgg atctaggcac aacgccaggt gactgcggat gtccatacat
3421 atacaaaagg ggcaatgacc ttgtggtcat tggggtgcac actgcagcag ctcgtggagg
3481 caacacggtc atatgtgcca cacagggaag tgaaggtgaa gccactcttg aaggaggtga
3541 caacaagggt acctattgtg gagcccccat tttgggacct ggcaatgcac caaaattgag
3601 cacaaagaca aaattctgga gatcctctaa cgcaccgctt cccccaggta cttatgaacc
3661 agcatacctt ggtgggagag acccgcgcgt gaagggaggc ccatctctgc aacaagttat
3721 gagagaccaa ctcaaacctt ttacagagcc cagagggaag ccaccaaacc caaatgtctt
3781 agagtcagca aagaagacta tcatcaatgt tctggaacaa accattgacc cccctcaaaa
3841 gtggtcatat gcccaagctt gtgcatccct cgacaagaca acctccagtg gatacccgca
3901 ccacgtccgg aagaatgact attggagtgg tgaatccttc acaggaaaac ttgcagatca
3961 ggcttcaaaa gcaaatctca tgtatgagga aggcaagcac atgcaaccag tttacaccgc
4021 agcactcaaa gacgagctcg tgaaaactga caaaatttat ggcaaaatca agaaaagact
4081 cctgtggggt tctgacctct ccacaatgat tcgatgcgcc agagcatttg gtggtctcat
4141 ggatgaattc aaagcaaatt gtattacact ccctgtcaga gttggtatga atatgaatga
4201 agatggtccc ataatatttg agaaacactc caggtacagg taccactatg atgctgatta
4261 ctcccgctgg gactccacac aacagcgggc agtgctggaa gcggcacttg aaatcatggt
4321 gagattttct gctgagccac agctggcaca aatagtggca gaggacctgc tgtcaccaag
4381 tgtggttgat gtgggcgatt tcaaaatcgc tatcaatgaa ggcctaccat ctggcgtgcc
4441 ttgcacctca caatggaatt ctattgccca ctggttactt accttgtgtg ccctttctga
4501 agtgacagga ttaggtcctg acatcataca agctaactcc atgtactctt tctatggtga
4561 tgatgagatt gtgagcacag acataaaatt ggacccagag aaactgaccg caaagctcaa
4621 agaatatggc cttaaaccca ctcggcccga caaaactgag gggccgttgg tgattagtga
4681 ggacctgaat gggttgactt tcctccgccg aacagtcacc cgtgatccag caggttggtt
4741 tggaaagttg gaccaaaact ccatcctcag gcagttgtac tggacaagag gacccaacca
4801 tgaagacccc agtgagacca tgataccaca cgcacaaaga cctgtgcagc tcatggcact
4861 actaggagaa tcctccctac atggaccctc attttacagc aaggttagca aattagtcat
4921 atctgaactt aaagagggag gaatggattt ttatgtgccc agacaagagt caatgttcag
4981 atggatgagg ttctcagatc taagcacatg ggagggcgat cgcaatctgg ctcccagttt
5041 tgtgaatgaa gatggcgtcg aatgacgccg ctccatctaa tgatggtgct gctggtctcg
5101 taccagaggg caacaacgag accctccccc tagaaccagt tgcgggcgca gctatagccg
5161 cacccgtcac tggccaaaat aacataattg acccctggat tagaacaaat tttgtgcaag
5221 caccaaatgg agagttcaca gtgtcaccca gaaactctcc tggagaaatt ttattaaact
5281 tagagttggg tcctgatttg aacccttatt tggctcattt gtcaaggatg tacaatgggt
5341 atgctggtgg agtggaagtt caggttctcc tggcagggaa cgcgttcact gccggaaaga
5401 tcctcttcgc cgccgtcccg ccaaatttcc cagtggaatt cttaagccca gcccagatca
5461 caatgctccc acatttaata gtagatgtta ggactcttga accaattatg atcccacttc
5521 ctgatgttag gaatacattc ttccattata gtaaccagcc taacagccgc atgagattag
5581 tggctatgct ctatacccca ctcagatcta atggctcagg tgatgatgtc tttactgtct
5641 cttgcagggt tttgactagg cctactcctg attttgagtt cacttattta gtgccacctt
5701 ctgttgaatc taaaactaag cctttctcct tacccatttt aaccctttct gagctcacaa
5761 attcgaggtt cccagtcccc atcgattcgc ttttcaccgc ccagaataat gtgttgcagg
5821 tgcagtgtca aaatggcagg tgtacacttg atggtgagtt acaaggcaca actcagttgc
5881 tcccatctgg catctgtgca ttcagaggac gggtgacagc acaaattaac caacgtgaca
5941 ggtggcacat gcaactgcaa aatctcaatg gtacaacata tgacccaact gatgatgtgc
6001 cagccccgct gggtacacct gacttcaagg gcgtcgtgtt tgggatggta agccaaagaa
6061 atgtgggtaa tgatgcgcct ggctcaacca gagcccaaca ggcgtgggtt tcaacttata
6121 gcccccaatt tgtccccaaa ttaggttctg ttaatcttag aattagtgat aatgatgatt
6181 tccaattcca gccgacaaaa ttcacaccag tgggcgtcaa tgatgacgat gatggccacc
6241 cgttcagaca atgggaacta ccaaactatt caggggagct taccttgaat atgaaccttg
6301 cccccccagt tgctccaaat tttcctggtg aacaattgtt attcttcaga tctttcgtgc
6361 catgctcagg aggttacaac caaggtatta tagattgtct tattccccaa gaatggatcc
6421 aacacttcta tcaggaatca gcaccctccc agtcagacgt ggccctaatc aggtatgtca
6481 accccgatac gggacgtaca ctgtttgaag caaaattgca cagatctggt tacatcactg
6541 tggctcactc tggagactat cctcttgttg ttccggctaa tggatacttc agatttgatt
6601 cttgggtaaa tcagttttac tcactcgccc caatgggaac tgggaatggg cgaaggaggg
6661 ctcagtaatg gctggggctt tcattgcagg attggcaggc gacatgctca cgtcatctgt
6721 gggctctctt gtgaacgcag gggcaaacgc catcaaccaa aagatagact ttgaaaacaa
6781 caaacaactc cagtctgctt cctttcagca tgataaagag atgctccaag cgcaggtgag
6841 ggcaaccaag cagctgcaat ctgaaatgat agccctaaaa cagggggttt tggccgcagg
6901 cggcttttcc cccactgatg cagcaagggg atccattggt gcacccatga caaaggtgct
6961 tgactggtct ggcactcgat actgggcgcc caattccaca aagacaactg gctattcggg
7021 acaattcacc tcttcacctg tgcatatgtc tagcccaaat gctccacaat caaaacctgc
7081 aaagcctagg tctctagttc cctcctcttc ttctagcagt gtctatagta tgtatactca
7141 atctactcat ttaacatctg gctcttctag taatgcttct tctgcctcca caaaattgac
7201 aaatttaagc tctggctcct ctcaaaacag aacagcagag tgggtaaatc aacagagaag
7261 tcttagccct ttcatgagtg gcgcacttaa catctcacat gtcacgccac cctcaagtag
7321 ggcttccagt tctgggacgg tctcgaccgt gcccaaggaa gttttggact cctggacgtc
7381 tgcgtttaac acacacagac agccgctctt cgcacacctc agagtgaggg gggagtcacg
7441 tgtttagtga aaagaaataa ttggctataa tgtgatttct ttctaaattt ggctaatttg
7501 tatcttttaa aaaaaaaa
//