Typing tool
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Typing tool
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Complete norovirus genomes
| KT152148 | GII.4 Den Haag | |
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| GII.P4 Den Haag |
ORF1: 6..5105
ORF2: 5086..6708
ORF3: 6708..7514
LOCUS KT152148 7564 bp RNA linear VRL 19-SEP-2018
DEFINITION Norovirus Hu/GII.P4_GII.4/Minerva/2006/USA, complete genome.
ACCESSION KT152148
VERSION KT152148.1
DBLINK BioProject: PRJNA490509
BioSample: SAMN10039973
KEYWORDS .
SOURCE Norovirus Hu/GII.P4_GII.4/Minerva/2006/USA
ORGANISM Norovirus Hu/GII.P4_GII.4/Minerva/2006/USA
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7564)
AUTHORS Yang,Z., Mammel,M.K. and Kulka,M.
TITLE Complete Genome Sequence of Human Norovirus GII.4_2006b, a Variant
of Minerva 2006
JOURNAL Genome Announc 4 (1), e01648-15 (2016)
PUBMED 26823589
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7564)
AUTHORS Yang,Z. and Kulka,M.
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2015) Molecular Virology Team/Division of
Molecular Biology/OARSA/CFSAN, Food and Drug Administration, 8301
Muirkirk Road, Laurel, MD 20708, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 8.0.1
Coverage :: 3437 X
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7564
/organism="Norovirus Hu/GII.P4_GII.4/Minerva/2006/USA"
/mol_type="genomic RNA"
/strain="Hu/GII.P4_GII.4/Minerva/2006/USA"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:1703222"
/country="USA"
/collection_date="2006"
/note="genotype: GII.P4_GII.4"
5'UTR 1..5
CDS 6..5105
/note="ORF1"
/codon_start=1
/product="non-structrual polyprotein"
/protein_id="ALA27426.1"
/translation="MKMASNDASAAAVANSNNDTAKSSSDKMFSNMAVTFKRALGARP
KQPPPREIPQRPPRPPTPELVKKIPLPPPNGEDEVVVSYSAKGGISGLPELSTVRQPE
ETNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVEQGLVLGVHKPPAAIS
LAKVELTPLSLFWRPVYTPQYLISPDTLKKLHGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTTDDSKLKKVANIFLCTLSSLFTRPIKDIIGK
LRPLNIINILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMITPLLGDFELQGPED
LVVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREV
AKRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSSDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVKTM
PELKQALKNISIKKCQIVYSGCTYTLESDGKGNVKVDRVQSTSVQTNNELAGALYHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIIKRVNIQDLWSKPQVENTEEATNKDGC
PKPKDDEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGGEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPSESMIPHSQRPIQLMSLLGEAALHGPTFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
CDS 5086..6708
/note="ORF2"
/codon_start=1
/product="major capsid protein"
/protein_id="ALA27427.1"
/translation="MKMASNDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGEDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMTNSRFPIPLEKLFTGPSGAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHIAGSRNYTMNLASLNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTKGDGSTRGHKATVYTGSAPFTPKLGSVQFSTDTENDFETHQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNVHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6708..7514
/note="ORF3"
/codon_start=1
/product="minor capsid protein"
/protein_id="ALA27428.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKIDFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRINPRAPTPARGSSSAPS
NASTATSIYSNQTVSTRLGSTAGSGTNVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRRRGESRV"
3'UTR 7515..7564
ORIGIN
1 cgtgaatgaa gatggcgtct aacgacgctt ccgctgccgc tgttgctaac agcaacaacg
61 acaccgcaaa atcttcaagt gacaaaatgt tttctaacat ggctgtcact tttaaacgag
121 ccctcggggc gcggcctaaa cagccccccc cgagggaaat accacaaaga cccccacgac
181 cacctactcc agaactggtc aaaaagatcc ctcttccccc gcccaacgga gaggatgaag
241 tagtggtttc ttatagtgcc aaaggtggca tttccggttt acctgagctt tccaccgtca
301 gacaaccaga agaaaccaat acggccttca gtgtccctcc actcaatcag agggagaata
361 gggatgctaa ggaaccactg actggaacaa ttctggaaat gtgggatgga gaaatctacc
421 attatggcct gtatgttgag caaggtcttg tgctgggtgt gcacaaacca ccagctgcca
481 ttagcctcgc caaggtcgaa ctaacaccac tctccttgtt ctggagacct gtgtacactc
541 ctcagtacct catctctcca gacactctca agaaattaca cggagaaaca tttccctaca
601 cagcctttga caacaattgc tatgcctttt gttgctgggt cctggaccta aacgactcgt
661 ggctgagtag gagaatgatc cagagaacaa ctggcttctt cagaccctac caagattgga
721 ataggaaacc cctccctact acggatgatt ccaaattaaa gaaggtagct aacatattcc
781 tgtgcaccct gtcttcgcta ttcaccaggc ccataaaaga cataatagga aagttaaggc
841 ctctcaacat catcaacatc ctggcttcat gtgattggac tttcgcaggc atagtggagt
901 ccttgatact cttggcagag ctctttggag tcttctggac acccccagat gtgtctgcga
961 tgattacccc cttactcggt gatttcgagt tacaaggacc tgaggacctt gtagtggagc
1021 tcgtccctgt agtaatgggg gggattggtt tggtgctagg attcaccaaa gagaagattg
1081 gaaaaatgtt gtcatctgct gcatccacct tgagagcttg taaagatctt ggtgcatatg
1141 ggctagagat cctaaagtta gtcatgaagt ggttcttccc gaagaaagag gaggcaaatg
1201 aactggctat ggtgagatcc atcgaggatg cagtactgga ccttgaggca attgaaaaca
1261 accatatgac caccttgctc aaagacaaag acagcctggc aacctacatg agaacccttg
1321 acctcgagga agagaaagcc agaaaactct caaccaagtc tgcttcacct gacatcgtgg
1381 gcacaatcaa cgcccttctg gcgagaatcg ccgctgcacg ctccctggtg caccgagcga
1441 aggaggagct ttccagcaga ccaagacctg tagtcttgat gatatcaggc agaccaggga
1501 tagggaagac ccaccttgct agggaagtgg ctaagagaat cgcagcctcc ctcacaggag
1561 accagcgtgt aggcctcatc ccacgcaatg gcgtcgatca ctgggatgcg tacaaggggg
1621 agagggtcgt cctatgggac gactatggaa tgagcaatcc catccacgac gccctcaggc
1681 tgcaagaact cgctgacact tgccccctca ctctaaattg tgacaggatt gagaataaag
1741 gaaaggtctt tgacagcgat gtcatcatta tcactactaa tctggccaac ccagcaccac
1801 tggactacgt caactttgaa gcgtgctcga gacgcatcga cttcctcgtg tatgcagaag
1861 cccccgaggt cgaaaaggcg aagcgtgact tcccgggcca acctgacatg tggaaaaacg
1921 cttttagttc tgatttctca cacataaaat tggcactggc tccacaaggt ggctttgata
1981 agaacgggaa caccccacac gggaagggcg tcatgaagac tctcaccact ggctccctca
2041 ttgcccgggc atcagggctg ctccatgaga gattggatga gtttgaacta cagggcccag
2101 ctcttaccac cttcaacttt gaccgcaaca aagtgcttgc cttcaggcag cttgctgctg
2161 aaaacaaata tgggttgatg gacacaatga aagttgggag gcagctcaag gatgtcaaaa
2221 ccatgccaga acttaaacaa gcactcaaga atatctcaat caagaagtgc cagattgtgt
2281 acagtggttg cacctacaca cttgagtctg atggcaaggg caatgtgaaa gttgacagag
2341 ttcagagcac ctccgtacag accaacaatg agctggctgg cgccctgtac catctaaggt
2401 gtgccagaat caggtactat gtcaagtgtg tccaggaggc cctgtattct atcatccaga
2461 ttgctggggc tgcatttgtc accacacgca tcatcaaacg tgtgaacatt caagacttat
2521 ggtccaagcc acaagtggaa aacacagagg aggctaccaa caaggacggg tgcccaaaac
2581 ccaaagatga tgaggagttc gtcatttcat ctgacgacat taaaactgag ggtaagaaag
2641 ggaagaacaa gactggccgt ggcaagaagc acacagcctt ctcaagtaaa ggtctcagtg
2701 atgaagagta tgatgagtac aagagaatta gagaggaaag gaatggcaag tactccatag
2761 aagaatacct tcaggacagg gacaaatact atgaggaggt ggccattgcc agggcgaccg
2821 aggaagactt ctgtgaagag gaggaggcca agatccggca aaggatcttc agaccaacaa
2881 ggaaacaacg caaggaagaa agagcttctc tcggtttagt cacaggttct gaaattagga
2941 aaagaaaccc agaagacttc aagcccaagg ggaaactatg ggctgacgat gacagaagtg
3001 tggactacaa tgagaaactc agttttgagg ccccgccaag catctggtca aggatagtca
3061 actttggctc aggttggggc ttctgggtct cccccagcct gttcataaca tcaacccacg
3121 tcatacccca gggcgcaaag gagttctttg gagtccccat caaacaaatt caggtacaca
3181 agtcaggcga attctgtcgc ttgaggttcc caaaaccaat caggactgat gtgactggca
3241 tgatcttgga agaaggtgcg cccgaaggca ccgtggccac actactcatc aaaaggtcta
3301 ctggagaact catgccccta gcagctagaa tggggaccca tgcaaccatg aaaattcaag
3361 ggcgcactgt tggaggtcag atgggcatgc ttctgacagg atctaacgcc aaaagcatgg
3421 atctaggcac cacaccaggt gattgcggct gtccctacat ctacaagaga ggaaatgact
3481 atgtggtcat tggagtccac acggctgccg ctcgtggggg aaacactgtc atatgtgcca
3541 cccagggggg tgagggggaa gctacacttg aaggtggtga cagtaaggga acatactgtg
3601 gtgcaccaat cctaggccca gggagcgccc caaaacttag caccaaaacc aaattctgga
3661 gatcatccac agcaccactc ccacctggca cctatgaacc agcctacctt ggtggcaagg
3721 accccagagt caagggtggc ccctcgttgc agcaagtcat gagggaccag ctgaaaccat
3781 ttacagagcc caggggtaag ccaccgaagc caagtgtgtt agaagctgcc aagaaaacca
3841 tcatcaatgt ccttgaacaa acaattgacc cacctgagaa gtggtcgttc gcacaagctt
3901 gcgcgtccct tgacaagacc acttctagcg gccacccgca ccacatgcgg aaaaacgact
3961 gctggaacgg ggagtccttc acaggcaagc tggcagacca ggcttccaag gccaacctga
4021 tgtttgaaga agggaagaac atgaccccag tttacacagg tgcacttaag gatgaattag
4081 tcaaaactga caaaatttat ggtaagatca agaagaggct tctctggggc tcggacttag
4141 caaccatgat ccggtgtgct cgagcattcg gaggcctaat ggatgaactc aaagcacact
4201 gtgtcacact tcctatcaga gttggtatga atatgaatga ggatggcccc atcatcttcg
4261 agaagcattc caggtacaga taccactatg atgctgatta ctctcggtgg gattcaacac
4321 aacagagagc cgtgctggca gctgctctgg aaatcatggt taaattctcc tcagaaccac
4381 atttggctca ggtagtcgca gaagaccttc tttctcctag cgtggtggat gtgggtgact
4441 tcacaatatc aatcaacgag ggtcttccct ctggggtgcc ctgcacctcc caatggaact
4501 ccatcgccca ctggcttctc actctctgtg cactctccga agttacaaat ttgtccccag
4561 acatcataca ggctaattct ctcttctcct tctatggtga tgatgaaatt gttagtacag
4621 acataaaact agacccagag aagttgacag caaagcttaa ggaatatggg ttgaaaccaa
4681 cccgccctga taaaactgaa ggacctcttg ttatttctga agacttagat ggtttgactt
4741 tcctgcggag aactgtgacc cgcgacccag ccggttggtt tggaaaactg gagcagagct
4801 caatactcag gcaaatgtac tggactaggg gccccaacca tgaagatcca tctgaatcaa
4861 tgattccaca ctctcagaga cccatacaat tgatgtcctt actgggagag gccgcactcc
4921 acggcccaac attctacagt aaaatcagca aattagtcat tgcagaacta aaagaaggtg
4981 gtatggattt ttacgtgccc aggcaagagc caatgttcag atggatgaga ttctcagatc
5041 tgagcacgtg ggagggcgat cgcaatctgg ctcccagttt tgtgaatgaa gatggcgtcg
5101 aatgacgcca acccatctga tgggtccgca gccaacctcg tcccagaggt caacaatgag
5161 gttatggctt tggagcccgt tgtcggtgcc gctattgcgg cgcctgtagc gggccaacaa
5221 aatgtaattg acccctggat tagaaataat tttgtacaag cccctggtgg agagttcaca
5281 gtgtccccta gaaacgctcc aggtgaaata ctgtggagcg cgcccttagg ccctgatctg
5341 aatccctacc tatctcattt ggccagaatg tataatggtt atgcaggtgg ttttgaagtg
5401 caagtgatcc tcgcggggaa cgcgttcacc gccggaaaaa ttatatttgc agcagtccca
5461 ccaaattttc caactgaagg cttgagcccc agccaggtca ctatgttccc ccacataata
5521 gtagatgtta ggcaattgga acctgtgttg atccccttac ctgatgttag gaataacttc
5581 tatcattata atcagtcaaa tgattctacc attaaattga tagcaatgct gtatacacca
5641 cttagggcta ataatgctgg ggaagatgtc ttcacagtct cttgccgagt cctcacgagg
5701 ccatcccctg attttgattt catatttttg gtgccaccta cagttgagtc aagaactaaa
5761 ccatttactg tcccaatctt aactgttgaa gagatgacca attcaagatt ccccattcct
5821 ttggaaaagt tgttcacggg tcccagcggt gcctttgttg ttcaaccaca aaatggcaga
5881 tgcacgactg atggcgtgct cttaggcacc acccaactgt ctcctgtcaa catctgcacc
5941 ttcagagggg atgtcactca cattgcaggt tctcgtaatt acacaatgaa tttggcttct
6001 ctaaattgga acaattatga cccaacagaa gaaattccag cccctctagg aactccagat
6061 ttcgtgggaa agatccaagg tgtgctcact caaaccacaa agggagatgg ctcgacccgt
6121 ggccataaag ctacagttta cactgggagt gcccccttta ctccaaagct gggcagtgtt
6181 caattcagta ctgatacaga aaatgatttt gaaactcacc aaaacacaaa attcacccca
6241 gtcggtgtca tccaggatgg tagcaccacc caccgaaatg aaccccaaca atgggtgctc
6301 ccaagttatt caggtagaaa tgtccataat gtacacctag cccctgctgt agcccccact
6361 tttccgggtg aacaacttct tttcttcagg tccactatgc ccggatgcag cgggtatccc
6421 aacatggatt tggattgcct actcccccag gagtgggtgc agcacttcta ccaagaggca
6481 gctccagcac aatctgatgt ggctctattg agatttgtaa atccagacac gggtagggtc
6541 ctgtttgagt gcaaacttca taaatcaggc tatgtcacag tggctcacac cggccagcat
6601 gatttggtca tcccccccaa tggctatttt aggtttgatt cctgggttaa tcaattctac
6661 acacttgccc ccatgggaaa tggaacgggg cgtagacgtg ctttataatg gctggagctt
6721 tctttgctgg attggcatct gatgtccttg gctctggact tggttctcta atcaacgctg
6781 gggctggggc tatcaaccaa aagattgatt ttgaaaataa cagaaaattg cagcaagctt
6841 ccttccagtt tagcagtaat ctacaacagg cttcctttca acatgacaaa gagatgctcc
6901 aagcacaaat tgaggccact aaaaagttgc aacaggaaat gatgaaagtc aaacaggcaa
6961 tgctcttaga aggtggattc tctgaaacag atgcagcccg tggggcaatc aatgccccca
7021 tgacaaaggc tttggactgg agcggaacaa ggtactgggc ccctgatgct aggactacaa
7081 catacaatgc aggccgcttt tccacccctc aaccttcggg ggcactgcca ggaagaatca
7141 atcccagggc tcctaccccc gctcggggct cctctagcgc accttctaat gcttctactg
7201 ctacttctat atattcaaat caaactgttt caacgagact tggttctaca gctggttctg
7261 gcaccaatgt ctcgagtctc ccgtcaactg caagaactag gagttgggtt gaggatcaaa
7321 acagaaattt gtcacctttc atgagggggg ctcacaacat atcgtttgtc accccaccat
7381 ctagcagatc ctctagccaa ggcacagtct caaccgtgcc taaagaagtt ttggactcct
7441 ggactggcgc tttcaacacg cgcaggcagc ctctcttcgc tcacattcgt aggcgagggg
7501 agtcacgggt gtaatgtgaa aagacaaaat tgattatctt tccttttctt tagtgtcttt
7561 taaa
//