Typing tool
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Typing tool
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Complete norovirus genomes
| KR232647 | GII.23 | |
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| GII.P23 |
ORF1: 1..4875
ORF2: 4856..6487
ORF3: 6487..7251
LOCUS KR232647 7259 bp RNA linear VRL 22-JAN-2018
DEFINITION Norovirus GII strain Hu/EC/2011/GII.P23-GII.23/Quininde1906
polyprotein gene, partial cds; and major capsid protein and minor
structural protein genes, complete cds.
ACCESSION KR232647
VERSION KR232647.2
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7259)
AUTHORS Lopman,B.A., Trivedi,T., Vicuna,Y., Costantini,V., Collins,N.,
Gregoricus,N., Parashar,U., Sandoval,C., Broncano,N., Vaca,M.,
Chico,M.E., Vinje,J. and Cooper,P.J.
TITLE Norovirus Infection and Disease in an Ecuadorian Birth Cohort:
Association of Certain Norovirus Genotypes With Host FUT2 Secretor
Status
JOURNAL J. Infect. Dis. 211 (11), 1813-1821 (2015)
PUBMED 25505295
REFERENCE 2 (bases 1 to 7259)
AUTHORS Collins,N., Lopman,B., Trivedi,T., Vicuna,Y., Costantini,V.,
Gregoricus,N., Parashar,U., Sandoval,C., Broncano,N., Vaca,M.,
Chico,M., Vinje,J. and Cooper,P.
TITLE Direct Submission
JOURNAL Submitted (22-APR-2015) NCIRD, DVD, GRVLB, CDC, 1600 Clifton Rd NE,
Atlanta, GA 30329, USA
REFERENCE 3 (bases 1 to 7259)
AUTHORS Chhabra,P., Cooper,P.J., Aswath,K., Collins,N., Castro,C.J. and
Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2017) Division of Viral Diseases, Center for
Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA
30329, USA
REMARK Sequence update by submitter
COMMENT On Dec 11, 2017 this sequence version replaced KR232647.1.
FEATURES Location/Qualifiers
source 1..7259
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Hu/EC/2011/GII.P23-GII.23/Quininde1906"
/isolate="3000091906"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/collection_date="10-Oct-2011"
/note="genotype: GII.P23-GII.23"
CDS <1..4875
/note="nonstructural protein; ORF1"
/codon_start=1
/product="polyprotein"
/protein_id="AUD07634.1"
/translation="PPPNGEDIVIKYTKQGDTVSGVPTVSTADISPLHDTAYSVPPLD
QREKVDAKEPLTGSILEMWDGEIYHYGLYVERGQVLGVHKPPAAVSVARIELTPLSLY
WRTVYTPPYLVAPDTLKKLHGETFPYTAFDNNCYSFCCWVLDLNDSWLNRKFVSRTTG
FYRPYQEWNRKPLPTMDEGKLKKVANVFLCGLSGLFTRPIKDLIGKLKPLNILNIVTN
CDWTFPGVVEAIILLAELFGIFWTPPDISAFVASLLGDYEMQGPEDIATEIVPVILGG
IGMVLGFTKEKIGRLLGSAASSLRACREIGNYGIEVVKLVMKWFFPTKSEVNEMEMVR
TIEDAVLDFEAIENNHMTALLKDKNSLATFLRALDMEEEKARKLSTKSASPDIVGTIN
ALLARIAAARSLVHRAKEEMSSRMRPVVIMISGRPGIGKTHLARDLAKKMAATLSGDQ
RVGLVPRNGVDHWDAYKGERIVLWDDYGMSNPVADALRLQELADTCPLTLNCDRIENK
GKVFDSDTLIITTNLANPAPLDYVNFEACSRRIDFLVYADSPSVDKAKRDFPGQPDMW
KDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTHSLIARATGLLHERLDEFD
LQGQELPVYNFDQNKVAAFRKLAADNKYGLMDTLRAGNKLKEVKNLDQFKEAVKDIRI
KPCRIIYNSMAYDLDSNGSGRVNVKKVGDQRVQANNELNSALNKLRGARIRYYVKCFQ
EMVYSLLQIAGAAFVTSRMAQRMNVNKLWTKPEKQQEASAGPPTPPTEEWTITPMNTV
QEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERQGKYSIEEYLQDRDRYYEE
LAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATLGLVTGSEIRKRNPDDFKPKG
KLWADDDRSVNYNERIDFEAPPSLWSRIVNFGSGWGFWVSSNLFITSTHVIPQNMSEA
FGVPISQIQIHRSGEFCKMRFPKAIRPDVSGMILEEGAPEGTVVTILIKRPTGELMPL
AARMGTHATMKIQGRMIGGQMGMLLTGSNAKNMDLGTVPGDCGCPYVYKRGNDWVVIG
VHTAAARGGNTVICATQGPDGEATLEGGDNHGTYCGAPILGPGNAPKLSTKTKFWRSS
NTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPFTAPRGKPPRPAVLEAAKETI
CNVLEQTIEPPQKWSYAQACASLDKTTSSGHPHHKKKNDNWNGETFTGVLADQASKAN
LMYEQGKHMQPVYTGALKDELVKTSKIYETIKKRLLWGSDLGTMIRCARSFGGLMDEM
KANCVNLPVRVGMNMNEDGPIIFEKHSKYRYHYDADYSRWDSTQQRCVLGAALDIMVR
YSAEPELAQIVAEDLLSPSVMDVGDFKITINEGLPSGVPCTSQWNSITHWLLTLCAMS
EVSGLSPDVVQSNSCFSFYGDDEIVSTDIKLDPQKLTDKLREYGLIPTRPDKTEGPLI
IRESLEGLTFLRRDVCRDPAGWYGKLDQSSIMRQLYWTKGPNHEDPNETMIPHSQRPV
QLMSLLGEAALHGPTFYKRVSKLVITELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGD
RNLAPESVNEDGVE"
CDS 4856..6487
/note="VP1; ORF2"
/codon_start=1
/product="major capsid protein"
/protein_id="AKF02368.1"
/translation="MKMASNDAAPSNDGAAGLVPEINNETMALEPVAGGAIAAPLTGQ
TNFIDPWIRGNYVQAPNGEFTVSPRNSPGEILLNLELGPELNPFLSHLSRMYNGYAGG
IDVQVIMAGNAFTAGKIIFAAIPPHFPVENLSPPQITMFPHIIVDVRTLEPINIPVPD
VRNNFFHYNQNNESRMRLVAMLYTPLRSNGSAEDVFTVSCRVLTKPSADFEFNYLVPP
TVESRTKPFTIPILTIGEMTNSRFPVPIDMLHTSPTENIVVQPQNGRCTIDGELLGTT
QLITSNICSFRGSISGHEGNDDQHLWHFNITNPNGTPFDPTEDVPAPLGTPDFRGQLY
GVISQRDREGTPSENNQKANRSHEGVISTISPKFVPKLGSVMIGTWTTDDIKNQPSKF
TPIGLNDDDNFKQWELPNYSGALTLNMGLAPSVFPTYPGEQVLFFRSYLPMKGGYGSP
FIDCLVPQEWVAHFYQESAPAQTDVALIRYVNPETGRVLFEAKLHRQGFITVAKSGDS
PINVPANGYFRFDSWVNQFYSLAPMGTGNGRRRIQ"
CDS 6487..7251
/note="VP2; ORF3"
/codon_start=1
/product="minor structural protein"
/protein_id="AUD07633.1"
/translation="MAGAFIAGLAGDMLTNTVGSLVNAGANAINQKIDFENNKYFQNA
SFAHDKDMLNAQVEATKKLQADMIAIKQGVLVAGGFSPTDAARGAINAPMTKVLDWNG
TRYWAPNATSTTSMSGGFTGQVSHRTTPNFKTNQAPKPPPSSGSSVRSNSTQLTSLSS
HSSGSSRSSGSTVVSSLPSSSRTRDWVNQQNLNLESHLPGSLRTAFVTPPSSSASSSG
TVSTVPKGVLDSWTSAFNTRRQPLFAHLRRRGESNV"
3'UTR 7252..>7259
ORIGIN
1 ccacccccaa atggtgagga catagtcatc aagtatacca aacaagggga tacagtcagc
61 ggagtgccca ccgtctccac tgcagacata tccccattgc atgacaccgc atatagtgtc
121 ccccccttgg accagaggga aaaggtggac gcaaaagaac ccctaactgg gtcaatactt
181 gagatgtggg atggtgagat ctaccattac gggctctatg tggagagagg gcaagttctc
241 ggtgtgcaca aaccaccggc tgctgtgagc gttgcacgca tcgaactgac ccccctctct
301 ctatactgga gaacagttta cacacctccc tacctggtgg ctcctgacac ccttaagaag
361 ctccacggtg agacattccc ctacacagca tttgataaca actgctactc attttgttgt
421 tgggttctgg acctgaacga ctcgtggctc aatagaaaat tcgtgtcaag gaccacaggc
481 ttctacagac cctaccagga gtggaacagg aaaccattgc caaccatgga cgaaggaaag
541 cttaagaagg tggccaacgt cttcctgtgt ggcctgtctg ggcttttcac caggcccatc
601 aaagatctca taggcaaact gaaaccactg aacatcctta acattgtcac caattgtgat
661 tggacgttcc cgggagtcgt agaggcgatc atcctcctcg cagagctctt tgggatcttc
721 tggacaccac cagacatatc tgccttcgtc gcctctctgt taggtgacta tgagatgcaa
781 ggccccgagg acattgcgac cgagatagtc ccagtcattc taggtggtat tggcatggta
841 cttggtttca ctaaagagaa gatcggccgg ctgctgggtt ccgcggcatc atcactcagg
901 gcctgcaggg aaatcggcaa ctatgggata gaggtggtaa aattggtgat gaaatggttc
961 tttccaacca aaagtgaggt caatgagatg gaaatggtca gaacaataga ggacgcagtg
1021 ctcgactttg aggcaattga aaacaatcac atgacagctc tactcaaaga caaaaatagt
1081 ctggccacct tcctcagggc actggatatg gaagaagaga aagcgcgaaa actttcaacc
1141 aaatccgcgt cccccgacat agtcggcact ataaatgcac tcctggcgag aattgccgct
1201 gctaggtcac tggtgcacag ggctaaggaa gagatgtcat caaggatgcg tcctgttgtc
1261 atcatgatat ccgggcgacc tgggataggg aaaacccatc tggcccgcga cctagctaag
1321 aaaatggcag ccactctgtc aggtgatcag agagtgggcc tggtcccaag gaatggtgtt
1381 gaccattggg atgcatacaa gggagaaagg atcgtcctgt gggatgatta cggtatgagc
1441 aaccccgtgg cagacgccct ccgactccag gaactcgccg atacatgccc cctgacactc
1501 aattgtgata ggatagagaa caaaggaaag gtctttgaca gtgacaccct gatcatcact
1561 actaatctgg ccaacccggc ccccctggac tatgtgaact ttgaagcttg ctcacgccgc
1621 atagatttcc ttgtttatgc ggactctccc tcagttgata aggcaaagag agacttccca
1681 ggccaaccag acatgtggaa agacgccttc aaaccagact tctcacacat aaagctacaa
1741 ctggcaccac agggaggatt tgacaagaat gggaacaccc cacatgggaa gggcgtcatg
1801 aaaacactaa ccacacactc cctcatagcc cgtgccactg gtttactcca tgagagatta
1861 gatgaatttg acttacaggg tcaagaattg ccagtctaca acttcgacca gaacaaggtg
1921 gccgctttcc ggaaactagc ggctgacaac aagtatggtc tcatggacac tttgagggca
1981 ggcaacaaac tgaaggaggt taagaatcta gaccaattca aggaagcggt gaaggacatc
2041 cgcataaagc cttgcaggat aatctacaac tcaatggctt atgatctgga ttcaaatggg
2101 tcaggcagag tcaatgttaa gaaagtggga gaccaaaggg tccaggccaa caatgaactc
2161 aactccgcac tcaacaaact gcgcggggct agaatcagat actatgtgaa gtgcttccag
2221 gaaatggtct actcccttct ccagattgct ggtgcggcct tcgttacatc aagaatggca
2281 caaagaatga atgtcaacaa gctgtggaca aaaccagaaa aacaacagga ggcctctgca
2341 gggcccccca cccccccaac tgaagagtgg accataacac caatgaacac ggtccaggaa
2401 ggtaagaagg gcaagaacaa aagtggtagg ggtaagaaac acactgcatt ctctagtaag
2461 ggccttagtg atgaggagta tgatgagtac aaaagaatca gggaggagcg ccaagggaag
2521 tactccatag aagaatacct ccaggacagg gaccggtact atgaagaatt ggccatagcc
2581 aaagcaacag aggaggactt ctgtgaagag gaggagatca agataaggca aagaattttc
2641 cgcccaacca ggaaacagcg tagggaggag agagccactc taggccttgt cacaggcagt
2701 gaaattagaa agaggaaccc cgatgatttc aaaccaaaag gaaaactgtg ggctgatgat
2761 gaccgtagtg tcaactacaa cgaaaggata gactttgaag cccctcccag cctctggtcc
2821 agaatagtca acttcggttc gggttggggc ttctgggtct catcaaattt gttcatcacc
2881 tccacacacg tcatcccaca aaacatgtct gaggctttcg gggtaccaat aagccaaatc
2941 caaatacata ggagtggaga gttctgcaaa atgaggttcc caaaggccat caggcccgat
3001 gtctctggca tgattcttga ggaaggcgcg cctgaaggca cggtggtgac catattgatc
3061 aaaagaccaa ctggtgaact catgccattg gcagctcgca tgggcaccca cgccaccatg
3121 aaaatacagg ggaggatgat tggaggtcaa atggggatgc ttctcacagg atccaacgcc
3181 aaaaacatgg accttggcac cgtgcctggt gattgtggct gcccttatgt ctacaaaaga
3241 ggcaatgatt gggtagttat cggggtgcac accgccgccg ccaggggtgg caacacggtg
3301 atctgtgcca ctcaggggcc agatggtgaa gccacacttg agggtggcga caaccatggg
3361 acctattgtg gcgcgccaat attaggtcca ggaaacgccc cgaaactcag caccaagacc
3421 aaattctgga ggtcctccaa cactccgctc ccccctggca catacgaacc agcctacctc
3481 ggtggtaagg acccaagagt caagggcggc ccatcactac aacaagtcat gagggagcaa
3541 ctcaagccct tcactgcccc acgtggaaaa ccaccaaggc cagcggtttt ggaggccgct
3601 aaggaaacca tctgcaatgt gctggagcaa accattgaac cgccccaaaa gtggtcctat
3661 gcacaggctt gtgcttccct agacaaaaca acctcaagtg gccaccccca ccacaagaag
3721 aaaaatgaca attggaacgg ggaaaccttc actggtgttc tggctgatca ggcttcaaaa
3781 gcaaacctca tgtatgagca agggaaacac atgcagcctg tgtacacagg cgcgctcaaa
3841 gatgagcttg tcaaaaccag caagatctat gaaaccatta agaagagact cttgtggggt
3901 tcagacctcg gcacaatgat acgctgtgcc aggtcatttg gtggtctcat ggatgaaatg
3961 aaggcaaact gtgtgaacct accagtcaga gttggcatga atatgaatga agatggtccc
4021 ataatctttg aaaagcattc aaagtacaga tatcactatg atgctgacta ttccaggtgg
4081 gactcaacac aacagagatg tgtcctgggt gctgcacttg atataatggt taggtactca
4141 gccgaaccag aattggcaca aatcgtggct gaggacttgc tgtcgcctag cgtcatggac
4201 gttggcgact tcaaaatcac cataaatgag ggcttaccat caggagttcc gtgcacatcc
4261 cagtggaact caataactca ttggctgtta acactctgtg ctatgtcaga agtctcagga
4321 ctgtcaccag atgtggtaca gtcaaattca tgcttctcct tctatgggga tgatgaaata
4381 gtcagcactg acatcaaatt ggacccccaa aaactgactg acaagttgag agagtatggc
4441 ttaattccaa ctagacccga caaaacagaa ggaccactta taatcagaga gagtctagaa
4501 ggcctaacat tcttaaggag ggatgtgtgc agagacccag cagggtggta tggcaaactt
4561 gaccaatcct caatcatgag acagttatac tggacaaaag ggcccaacca tgaggacccc
4621 aatgaaacaa tgatcccaca ttcccagagg ccagtgcaat tgatgtccct acttggtgag
4681 gcggccctac acggaccgac attctataag agagttagca agttggtcat cactgaatta
4741 aaggaaggtg ggatggattt ctatgtgccc agacaagaac ctatgtttag atggatgaga
4801 ttctctgact tgagcacgtg ggagggcgat cgcaatctgg ctcccgaaag tgtgaatgaa
4861 gatggcgtcg aatgacgccg ctccatctaa tgatggtgca gccggtctcg taccagagat
4921 caacaacgag acaatggctt tggaaccagt ggcaggagga gcaattgcag ccccactaac
4981 tggacaaaca aatttcattg atccctggat tagaggtaat tatgtgcaag caccaaatgg
5041 tgaatttaca gtgtccccca gaaattcgcc cggtgaaatt ttgcttaatt tagaattagg
5101 ccctgaactc aacccattct tgtcccatct atctagaatg tacaatgggt atgctggcgg
5161 tattgatgtc caagtcatca tggcaggcaa tgccttcacc gctggtaaga ttatctttgc
5221 agcaatacct ccccacttcc ccgtggaaaa tcttagtccc cctcagatca ctatgttccc
5281 tcatattata gtggatgtca ggacccttga acccataaac atccctgtac cagatgttag
5341 gaacaacttc ttccattata atcaaaacaa tgagtctcgc atgagactgg tggccatgtt
5401 gtacacccct cttaggtcta atgggtctgc tgaagatgtt ttcacagtgt catgtagggt
5461 cttaacaaaa ccatctgcag actttgaatt caattatcta gtccccccaa ctgtagagtc
5521 aaggactaaa cccttcacaa taccaatact cacaattggg gaaatgacaa attcaagatt
5581 cccagtgcct attgacatgc ttcataccag tccaacagaa aacattgttg ttcaaccaca
5641 aaatggcagg tgcaccatag atggtgagtt gcttggcacc actcaactga tcacttccaa
5701 tatctgttca ttcagagggt ccatctcagg gcatgagggc aatgatgacc aacacctgtg
5761 gcacttcaac atcacaaacc ccaatggcac tccatttgac cccactgaag atgtgcctgc
5821 ccccctcgga accccagatt tcaggggtca attgtacggt gtcatctccc agcgagatag
5881 agagggaaca ccctcggaaa acaatcagaa ggcaaacagg tcccacgagg gggtgatttc
5941 aacaatctca ccaaaatttg tccccaagtt aggttcagtc atgattggca catggactac
6001 tgacgatatc aagaaccagc catccaagtt caccccaatt ggcctcaatg atgatgataa
6061 ttttaaacaa tgggaactgc caaattattc tggggcgctc accctcaaca tggggttggc
6121 acctagtgtt ttccccacct accctggtga acaagtcctt ttcttccgct cctatctgcc
6181 aatgaaggga gggtacggta gtccatttat tgactgccta gtacctcaag aatgggtcgc
6241 tcacttctac caggagtcag cacccgcaca aacagatgtg gccctaatta ggtatgtaaa
6301 ccccgaaaca ggacgtgtcc ttttcgaggc caaattgcac agacaggggt ttattaccgt
6361 tgccaagagc ggcgacagcc ccatcaatgt gcctgccaat ggttatttta ggtttgattc
6421 ttgggttaat cagttttact ctcttgcccc catgggaact gggaacgggc gcagaaggat
6481 tcagtaatgg ctggagcttt tatagcagga ttggctggtg acatgctcac aaacactgta
6541 gggtctctag ttaatgcagg agctaatgct attaatcaga aaattgattt tgagaataat
6601 aaatatttcc aaaatgcatc atttgcccat gataaggata tgctgaatgc acaggttgag
6661 gcgaccaaga aacttcaggc tgacatgatt gccatcaagc aaggggtatt agtcgcgggc
6721 ggcttttccc ctactgatgc agctcgggga gcaatcaatg cccccatgac aaaagttcta
6781 gattggaatg gaacaaggta ctgggcgcca aatgccacct ccaccacttc aatgtcaggt
6841 ggcttcacag gacaggtttc gcacaggacc acaccaaatt ttaaaaccaa ccaggccccc
6901 aagcccccac ctagtagtgg ttcttcagta aggtccaact caacccaact cactagtctg
6961 agctcccact cctctgggtc atctcgatct agcggatcaa cagtggttag ctctttgcct
7021 tcttctagca ggactaggga ttgggtcaat caacaaaatc tcaatttgga atcacatttg
7081 cctgggtctc tcagaacagc ttttgtcact ccaccatcta gttcagcctc tagttcaggc
7141 acagtctcaa ccgtgcctaa gggtgttttg gactcctgga catctgcatt caacacacgc
7201 agacagccgc tttttgcaca ccttcgcaga aggggggagt caaatgttta gtgaaaaga
//