Typing tool
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Typing tool
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Complete norovirus genomes
| GU325839 | GII.4 Den Haag | |
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| GII.P4 Den Haag |
ORF1: 5..5104
ORF2: 5085..6707
ORF3: 6707..7513
LOCUS GU325839 7560 bp RNA linear VRL 06-SEP-2011
DEFINITION Norovirus Hu/GII.4/HS194/2009/US, complete genome.
ACCESSION GU325839
VERSION GU325839.2
KEYWORDS .
SOURCE Norovirus Hu/GII.4/HS194/2009/US
ORGANISM Norovirus Hu/GII.4/HS194/2009/US
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7560)
AUTHORS Takanashi,S., Wang,Q., Chen,N., Shen,Q., Jung,K., Zhang,Z.,
Yokoyama,M., Lindesmith,L.C., Baric,R.S. and Saif,L.J.
TITLE Characterization of Emerging GII.g/GII.12 Noroviruses from a
Gastroenteritis Outbreak in the United States in 2010
JOURNAL J. Clin. Microbiol. 49 (9), 3234-3244 (2011)
PUBMED 21752978
REFERENCE 2 (bases 1 to 7560)
AUTHORS Chen,N., Wang,Q. and Saif,L.J.
TITLE Sequence analysis of the complete genome of a GII.4 Norovirus
strain
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 7560)
AUTHORS Wang,Q., Zhang,Z. and Saif,L.J.
TITLE Direct Submission
JOURNAL Submitted (15-DEC-2009) Food Animal Health Research Program,
OARDC/The Ohio State University, 1680 Madison Ave., Wooster, OH
44691, USA
REFERENCE 4 (bases 1 to 7560)
AUTHORS Chen,N., Wang,Q. and Saif,L.J.
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2011) Food Animal Health Research Program,
OARDC/The Ohio State University, 1680 Madison Ave., Wooster, OH
44691, USA
REMARK Sequence update by submitter
COMMENT On May 26, 2011 this sequence version replaced GU325839.1.
FEATURES Location/Qualifiers
source 1..7560
/organism="Norovirus Hu/GII.4/HS194/2009/US"
/mol_type="genomic RNA"
/strain="Hu/GII.4/HS194/2009/US"
/host="Homo sapiens"
/db_xref="taxon:706195"
/country="USA"
/collection_date="2009"
/note="genotype: GII.4"
CDS 5..5104
/note="orf1; encodes 2C helicase, 3C protease, and 3D
RNA-dependent RNA polymerase"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="AEG64833.1"
/translation="MKMASNDASAAAVANSNNDTAKSSNDKMFSNMAVTLKRALGARP
KQPPPREIPQRPPRPPTPELVKKIPPPPPNGEDEAVISYSAKDGVSGLPELSTVRQPE
ETNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LAKVELTPLSLFWRPVYTPQYLISPDTLKKLHGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCALSSLFTRPIKDIIGK
LRPLNIINILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDFELQGPED
LVVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREV
AKRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSSDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVKTM
PELKQALKNISIKKCQIVYSGCTYTLESDGKGNVKVDRVQSTSVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIIKRVNIQDLWSKPQVENTEEATSKDGC
PKPKDDEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVVTLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGGEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPSESMIPHSQRPIQLMSLLGEAALHGPTFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
CDS 5085..6707
/note="major structural protein; orf2"
/codon_start=1
/product="capsid protein VP1"
/protein_id="ADB27914.1"
/translation="MKMASNDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHIAGSRNYTMNLASLNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTKGDGSTRGHKATVYTGSADFTPKLGSVQFGTDTENDFETHQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNVHNVHLAPAVAPNFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6707..7513
/note="minor structural protein; orf3"
/codon_start=1
/product="small basic protein VP2"
/protein_id="ADB27915.1"
/translation="MAGAFFAGLASDVLSSGLGSLINAGAGAINQKIDFENNRKLQQA
SFQFNSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARITTYNAGRFSTPQPSGALPGRINPRTPTPARGSPSISS
NASTATSIYSNQTVSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRKQPLFAHIRRRGESRV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgctgccgct gttgccaaca gcaacaacga
61 caccgcaaaa tcttcaaatg acaaaatgtt ttctaacatg gctgtcactc ttaaacgagc
121 cctcggggcg cggcctaaac agcccccccc gagggaaata ccacaaagac ccccacgacc
181 acctactcca gaactggtca aaaagatccc tcctccccca cccaacggag aggatgaagc
241 agtgatttct tatagtgcca aagatggcgt ttccggtttg cctgagcttt ccaccgtcag
301 gcaaccggaa gaaaccaata cggccttcag tgtccctcca ctcaatcaga gggagaatag
361 ggatgctaag gaaccactga ctggaacaat tctggaaatg tgggatggag aaatctacca
421 ttatggcctg tatgttgagc gaggtcttgt gctgggtgta cacaaaccac cagctgccat
481 tagcctcgcc aaggtcgaac taacaccact ctccttgttc tggagacctg tgtacactcc
541 tcagtacctc atttctccag acactctcaa gaaattacac ggagaaacat ttccctacac
601 agcctttgac aacaattgct atgccttttg ttgctgggtc ctggatctaa acgactcgtg
661 gctgagtagg agaatgatcc agagaacaac tggcttcttc agaccctacc aagattggaa
721 taggaaaccc ctccccacta tggatgattc caaattaaag aaggtagcta acatattcct
781 gtgcgccctg tcttcgctat tcaccaggcc cataaaagac ataataggaa agttaaggcc
841 tctcaatatc atcaacatcc tggcttcatg tgattggact ttcgcaggca tagtggagtc
901 cttgatactc ttggcagagc tctttggagt cttctggaca cccccagatg tgtctgcgat
961 gattgccccc ttactcggtg atttcgagtt acaaggacct gaggaccttg tagtggagct
1021 cgtccctgta gtaatggggg ggattggttt ggtgctagga ttcaccaaag agaagattgg
1081 aaaaatgttg tcatctgctg catccacctt gagagcttgt aaagaccttg gtgcatatgg
1141 gctagagatc ctaaagttag tcatgaagtg gttcttcccc aagaaagagg aagcgaatga
1201 actggctatg gtgagatcca tcgaggatgc agtactggac cttgaggcaa ttgaaaacaa
1261 ccatatgacc accttgctca aagacaaaga cagcctggca acctacatga gaaccctcga
1321 cctcgaggaa gagaaagcca gaaaactctc aaccaagtct gcttcacctg acatcgtggg
1381 cacaatcaac gcccttctgg cgagaatcgc cgctgcacgt tctctggtgc accgagcgaa
1441 ggaggagctt tccagcagac caagacctgt agtcttgatg atatcaggca ggccaggaat
1501 agggaagacc caccttgcta gggaagtggc taagagaatc gcagcctccc tcacaggaga
1561 ccagcgtgta ggcctcattc cacgcaatgg cgtcgatcac tgggatgcgt acaaggggga
1621 gagggtcgtc ctatgggacg actatggaat gagcaatccc atccacgacg ccctcaggct
1681 gcaagaactc gctgacactt gccccctcac tctaaattgt gacaggattg agaataaagg
1741 aaaggtcttt gacagcgatg tcatcattat cactactaat ctggccaacc cagcaccact
1801 ggactatgtc aactttgaag cgtgctcgag gcgcatcgac ttcctcgtgt atgcagaagc
1861 ccccgaggtc gaaaaggcga agcgcgactt cccgggccaa cctgacatgt ggaaaaacgc
1921 ttttagttct gatttctcac acataaaatt ggcactggct ccacaaggtg gctttgacaa
1981 gaacgggaac accccacacg ggaagggcgt catgaagact ctcaccactg gctccctcat
2041 tgcccgggcg tcagggctgc tccatgagag attggatgag tttgaactac agggcccagc
2101 tctcaccacc ttcaactttg accgcaacaa agtgcttgcc ttcaggcagc ttgctgctga
2161 aaacaaatat gggttgatgg acacaatgaa agttgggagg cagctcaagg acgtcaaaac
2221 catgccagaa cttaaacaag cactcaagaa tatctcaatc aagaagtgcc agattgtgta
2281 cagtggttgc acctacacac ttgagtctga tggcaagggc aatgtgaaag ttgacagagt
2341 tcagagtacc tccgttcaga ccaacaatga gctggctggc gccctgcacc atctaaggtg
2401 cgccagaatc aggtactatg tcaagtgtgt tcaggaggcc ctgtattcta tcatccagat
2461 tgctggggcc gcatttgtca ccacgcgcat catcaagcgt gtgaacattc aagacttatg
2521 gtccaagcca caagtggaaa acacagagga ggctaccagc aaggacgggt gcccaaaacc
2581 caaagatgat gaggagttcg tcatttcatc tgacgacatt aaaactgagg gtaagaaagg
2641 gaagaacaag actggccgtg gcaagaagca cacagccttc tcaagtaaag gtctcagtga
2701 tgaagagtat gatgagtaca agagaattag agaggaaaga aatggcaagt actccataga
2761 agagtacctc caggacaggg acaaatacta tgaggaggtg gccattgcca gggctaccga
2821 ggaagacttc tgtgaagagg aggaggccaa gatccggcag aggatcttca gaccaacaag
2881 gaaacaacgc aaggaagaaa gagcttctct cggtttagtc acaggttctg aaattaggaa
2941 aagaaatcca gaagacttca agcccaaggg gaaactatgg gctgacgatg acagaagtgt
3001 ggactacaat gaaaagctca gttttgaggc cccaccaagc atctggtcaa ggatagtcaa
3061 ctttggctca ggttggggct tctgggtctc ccccagccta ttcataacat caacccacgt
3121 cataccccag ggcgcaaagg agttctttgg agtccccatc aaacaaattc aggtgcacaa
3181 gtcaggcgaa ttctgtcgct tgaggttccc aaaaccaatc aggactgatg tgactggcat
3241 gatcttggaa gaaggtgcgc ccgaaggcac cgtggtcaca ctactcatca aaagacccac
3301 tggagaactc atgcccctag cagctagaat ggggacccat gcaaccatga agattcaagg
3361 gcgcactgtt ggaggtcaga tgggcatgct tctgacagga tccaacgcca aaagcatgga
3421 tctaggcacc acaccaggtg attgcggctg tccctacatc tacaagagag gaaacgacta
3481 tgtggtcatt ggagtccaca cggctgccgc tcgtggggga aacactgtca tatgtgccac
3541 ccaggggggt gagggggagg ctacacttga aggtggtgac agtaagggaa catactgtgg
3601 tgcaccaatc ctaggcccag ggagtgcccc aaaacttagc accaaaacca aattctggag
3661 atcatccaca gcaccactcc cacctggcac ctatgaacca gcctaccttg gtggcaaaga
3721 ccccagagtc aagggtggcc cctcgttgca gcaagtcatg agggaccagc tgaaaccatt
3781 tacagagcct aggggtaagc caccaaagcc aagtgtgtta gaagctgcca agaaaaccat
3841 catcaatgtc cttgaacaga caattgaccc acctgagaag tggtcgttcg cacaagcttg
3901 cgcgtccctt gacaagacca cttctagcgg ccacccgcac cacatgcgga aaaacgactg
3961 ctggaacggg gaatctttca caggcaagct ggcagaccag gcttccaagg ccaacctgat
4021 gtttgaagaa gggaagaaca tgaccccagt ctacacaggt gcacttaagg atgaattagt
4081 caaaactgac aaaatttatg gtaagatcaa gaagagactt ctctggggct cggacttagc
4141 aaccatgatc cggtgtgctc gagcattcgg aggtctgatg gatgaactca aagcacactg
4201 tgtcacactt cctgtcagag ttggtatgaa tatgaatgag gatggcccca tcatcttcga
4261 gaagcattcc aggtacagat accactatga tgctgattac tctcggtggg attcaacaca
4321 acagagagcc gtgctggcag ctgctctaga aatcatggtt aaattctcct cagaaccaca
4381 cttagctcag gtagtagcag aagaccttct ttctcctagc gtggtagatg tgggcgactt
4441 cacaatatca atcaacgagg gtcttccctc tggggtgccc tgcacctccc aatggaactc
4501 catcgcccac tggcttctca ctctctgtgc actctccgaa gtcacaaatt tgtccccaga
4561 catcatacag gctaattctc tcttctcctt ctatggtgat gatgaaattg ttagtacaga
4621 cataaaatta gacccagaga agttgacagc aaagcttaag gaatatgggt tgaaaccaac
4681 ccgccctgac aaaactgaag gaccccttgt tatttctgaa gacttagacg gtttgacttt
4741 cctgcggaga actgtgaccc gcgacccagc tggttggttt ggaaaactgg agcagagctc
4801 aatactcagg caaatgtact ggactagggg ccccaatcat gaagacccat ctgaatcaat
4861 gatcccacac tctcaaagac ccatacaatt gatgtcctta ctgggagagg ccgcactcca
4921 cggcccaaca ttctacagta aaatcagcaa attagtcatt gcagagctaa aagaaggtgg
4981 catggatttt tacgtgccca ggcaagagcc aatgttcaga tggatgagat tctcggatct
5041 gagcacgtgg gagggcgatc gcaatctggc tcccagtttt gtgaatgaag atggcgtcga
5101 atgacgccaa cccatctgat gggtccgcag ccaacctcgt cccagaggtc aacaatgagg
5161 ttatggcttt ggagcccgtt gtcggtgccg ctattgcggc gcctgtagcg ggccaacaaa
5221 atgtaattga cccctggatt agaaataatt ttgtacaagc ccctggtgga gagttcacag
5281 tatcccctag aaacgctcca ggtgaaatac tatggagcgc gcccttgggc cccgatctga
5341 atccctacct atcacatttg gccagaatgt ataatggtta tgcaggtggt tttgaagtgc
5401 aggtgatcct cgcggggaac gcgttcaccg ccggaaaaat tatatttgca gcagtcccac
5461 caaattttcc aactgaaggc ctgagtccca gccaggttac tatgttcccc cacataatag
5521 tagatgttag gcaattggaa cctgtgttga tccccttacc tgatgttagg aataacttct
5581 atcattataa tcagtcaaat gattccacca ttaaattgat agcaatgctg tatacaccac
5641 ttagggccaa taatgctggg gatgatgtct tcacagtctc ttgtcgagtc ctcacgaggc
5701 catcccctga ttttgacttt atatttttgg tgccacctac agttgagtca agaactaagc
5761 catttactgt cccaatctta actgttgaag aaatgactaa ttcaagattc cccattcctt
5821 tggaaaaatt gttcacgggt cccagcagtg cctttgttgt tcaaccacaa aatggcagat
5881 gcacgactga tggcgtgctc ttaggcacca cccaactgtc tcctgtcaac atctgcacct
5941 tcagagggga tgtcacccac attgcgggtt ctcgcaatta cacaatgaat ttggcatctc
6001 taaattggaa caattatgac ccaacagaag aaattccagc ccctctggga actccagatt
6061 tcgtgggaaa gatccaaggt gtgctcactc agacaacaaa gggagatggc tcgacccggg
6121 gccataaagc tacagtttac actgggagtg ccgactttac tccaaagctg ggcagtgttc
6181 aatttggtac tgatacagaa aatgactttg aaactcacca aaacacaaaa ttcaccccag
6241 tcggtgtcat ccaggatggt agcaccaccc accgaaatga accccaacaa tgggtgctcc
6301 caagttattc aggcagaaat gtccataatg tgcacttagc ccctgctgta gcccccaatt
6361 ttccgggtga acaacttctt ttcttcaggt ccactatgcc cggatgcagc gggtatccca
6421 acatggattt ggactgccta ctcccccagg agtgggtgca gcacttctat caagaggcag
6481 ctccagcaca atctgatgtg gctctattga gatttgtgaa tccagacacg ggtagagtcc
6541 tgtttgagtg caaacttcat aaatcaggct atgtcacagt ggctcacacc ggccaacatg
6601 atttggtcat cccccccaat ggctatttta gatttgattc ctgggttaat caattctaca
6661 cacttgcccc catgggaaat ggaacggggc gtagacgtgc tttataatgg ctggggcttt
6721 ctttgctgga ttggcatctg atgtccttag ctctggactt ggttccctaa tcaatgctgg
6781 ggctggggcc atcaaccaaa agattgattt tgaaaataat agaaaattgc agcaagcttc
6841 tttccagttt aacagtaatc tacaacaggc ttcctttcaa catgataaag agatgctcca
6901 agcacaaatt gaggccacta aaaagttgca gcaggaaatg atgaaagtca aacaggcaat
6961 gctcttagaa ggtggattct ctgaaacaga tgcagcccgt ggggcaatca acgcccccat
7021 gacaaaggct ttggactgga gcggaacaag gtactgggcc cctgatgcta gaattacaac
7081 atacaatgca ggccgctttt ccacccctca accttcgggg gcgctgccag gaagaatcaa
7141 tcccaggact cctacccccg ctcggggctc ccccagcata tcttccaatg cttctactgc
7201 tacttctata tactcaaatc aaactgtttc aacgagactt ggttctacag ctggttctgg
7261 caccagtgtc tcgagtctcc cgtcaactgc aaggactagg agttgggttg aggatcaaaa
7321 cagaaatttg tcacctttca tgaggggggc tcacaacata tcgtttgtca ccccaccatc
7381 tagcagatcc tccagccaag gcacagtctc aaccgtgcct aaagaagttt tggactcctg
7441 gactggcgct ttcaacacgc gcaagcagcc tctcttcgct cacatccgta ggcgagggga
7501 gtcacgggtg taatgtgaaa agacaaaatt gattatcttt ccttttcttt agtgtctttt
//