Typing tool
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Typing tool
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Complete norovirus genomes
| FJ537138 | GII.4 | |
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| GII.P39 |
ORF1: 5..5104
ORF2: 5085..6704
ORF3: 6704..7510
LOCUS FJ537138 7580 bp RNA linear VRL 02-NOV-2009
DEFINITION Norovirus Hu/GII.4/CHDC4871/1977/US, complete genome.
ACCESSION FJ537138
VERSION FJ537138.1
KEYWORDS .
SOURCE Norovirus Hu/GII.4/CHDC4871/1977/US
ORGANISM Norovirus Hu/GII.4/CHDC4871/1977/US
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7580)
AUTHORS Bok,K., Abente,E.J., Realpe-Quintero,M., Mitra,T., Sosnovtsev,S.V.,
Kapikian,A.Z. and Green,K.Y.
TITLE Evolutionary dynamics of GII.4 noroviruses over a 34-year period
JOURNAL J. Virol. 83 (22), 11890-11901 (2009)
PUBMED 19759138
REFERENCE 2 (bases 1 to 7580)
AUTHORS Bok,K., Abente,E.J., Realpe-Quintero,M., Mitra,T., Sosnovtsev,S.V.,
Kapikian,A.Z. and Green,K.Y.
TITLE Direct Submission
JOURNAL Submitted (10-DEC-2008) Laboratory of Infectious Diseases,
Epidemiology Section, Norovirus Gastroenteritis Unit, National
Institute of Allergy and Infectious Diseases, National Institutes
of Health, 50 South Drive, BLD 50, Room 6316, Bethesda, MD 20892,
USA
FEATURES Location/Qualifiers
source 1..7580
/organism="Norovirus Hu/GII.4/CHDC4871/1977/US"
/mol_type="genomic RNA"
/strain="Hu/GII.4/CHDC4871/1977/US"
/host="Homo sapiens"
/db_xref="taxon:660659"
/country="USA"
/collection_date="1977"
/note="genotype: GII.4"
CDS 5..5104
/note="ORF-1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="ACT76150.1"
/translation="MKMASNDASAAAAANGNNDTAKSSSDGVLSSMAVTFKRALGARP
KQPPPREIPQRPPRPPTPELIKKVPPPPPNGEDEPVVSYNAKNGVSGLPELSTVRQPD
ENNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LAKVELTPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCALSSLFTRPIKDIIGK
LRPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEASELAMVRSIEDAVLDLEAIENNHLTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVVMISGKPGIGKTHLAREL
AKKIATTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPDVEK
AKRDFPGQPDMWKNAFSPDFSHIKLVLAPQGGFDKNGNTPHGKGVMKTLTIGSLIARA
SGLLHERLDEYELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGGQLKGVRTM
PELKQALKNISIKKCQIVYGGSTYTLESDGKGSVRVDKVQSATVQTNNELAGALHHLR
CARVRYYVKCVQEALYSIIQIAGAAFVTTRIVKRMNIQDLWSKPQLEDTEEATGKDGC
PKPKDDEEFVVSSDDIKVEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGTQEFFGVSIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRIKGGPSLQQVMRDQLKPFTEP
RGKQPKPSVLEAAKRTIINVLEQTIDPPQKWTFAQACASLDKTTSSGHPHHIRKNECW
NGDSFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAILAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFKISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIVQANSLFSFYGDDEIVSTDIKMDPEKLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPSETMIPHSQRPTQLMSLLGEAALHGPAFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
CDS 5085..6704
/note="structural protein; ORF-2"
/codon_start=1
/product="VP1"
/protein_id="ACT76151.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLSRMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQAHDSTLKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMSNSRFPIPLEKLYTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSAVNICNFRGDVTRVGISHDYTMNLVSQNWNNYDPTEEIPAPLGTPDFVGKIQGLL
TQTTRADGSTRAHKATVSTGSVHFTPKLGSVQFTTDTNNDFQTGQNTKFTPVGVIQDG
DHHQNEPQQWVLPNYSGTSGHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMNLDC
LLPQEWVLHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYITVAHTGPYDLVI
PPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6704..7510
/note="structural protein; ORF-3"
/codon_start=1
/product="VP2"
/protein_id="ACT76152.1"
/translation="MAGPFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATQKLQQGLMKVKQAVLLEGGFSTTDAARGAIN
APMTKALDWSGTRYWAPDARVTTYNAGRFSTPQPLGALPGRTNPRVPAPARSSPSSLS
NAPTATSVYSNQTVSTRLGSSAGSGAGVSSLPSTARTRSWVEDQNRNLSPFMRGALNT
SFVTPPSSRSSNQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgctgccgct gctgctaacg gcaacaacga
61 caccgcaaaa tcttcaagtg acggagtact ttctagtatg gctgtcactt ttaaacgagc
121 ccttggggcg cggcctaagc agccgccccc gagggagata ccacaaagac ccccacgacc
181 gcccactccg gaattgatca agaaggtccc tccccccccg cccaatgggg aggacgaacc
241 agtggtttct tacaacgcca agaatggcgt ttctggactg cctgagcttt ccactgtcag
301 gcaaccagat gagaacaaca cggcatttag tgtcccccca cttaaccaaa gggagaacag
361 ggatgccaag gagccactaa ctggaacaat cctggagatg tgggatgggg agatctacca
421 ttatggcttg tatgtggagc gaggcctggt gcttggcgtg cacaaaccgc cagcagctat
481 tagcctcgct aaggtcgaac tgacaccact ctctttgttt tggagacccg tctacactcc
541 ccagtacctc atctccccag acacccttag gagattgcat ggtgaatcgt tcccttacac
601 agcctttgac aacaactgtt atgccttctg ttgctgggtt ctggacctga acgattcatg
661 gctgagcagg aggatgatac agaggacaac tggcttcttc agaccttacc aggattggaa
721 caggaagccc cttcccacca tggatgattc caaattaaag aaagtggcca acatattcct
781 gtgtgctttg tcttcactat tcactagacc tatcaaggac ataataggaa agctaagacc
841 ccttaacatt ctcaatattt tagcttcatg tgattggacc tttgcaggca tagtggaatc
901 tctaatcctc ttggcagaac tctttggagt tttctggaca cccccagatg tgtctgcgat
961 gattgccccc ttactgggtg actacgaact acaggggcct gaggacctcg cagtagagct
1021 agtgccagta gtaatggggg gaataggttt ggtgctagga tttaccaaag aaaagattgg
1081 gaagatgttg tcatctgccg cgtccacact gagggcctgt aaagaccttg gtgcatatgg
1141 gctggagatc ttaaaactag tcatgaagtg gttcttcccg aagaaagagg aggcgagtga
1201 gttggccatg gtgagatcca tcgaggacgc ggtgttggac ctcgaagcaa ttgaaaacaa
1261 ccatttgacc accctgctta aggacaagga cagcctggca acttacatga gaactcttga
1321 ccttgaggaa gagaaagcca ggaaactctc aaccaagtct gcctcacctg acatcgtggg
1381 tacaatcaat gctctcctgg cgaggatcgc ggctgcccgt tccctggtac atcgagcaaa
1441 ggaagaactt tccagcaggc cgagacccgt tgttgtgatg atatcaggaa aaccaggaat
1501 agggaagacc caccttgcca gagagctggc taagaagatc gcaaccaccc ttacgggaga
1561 ccagagggtg ggcctcatcc cacgcaatgg tgttgaccac tgggacgcgt acaagggaga
1621 gagggtcgtc ctctgggatg actacggtat gagtaacccc atccacgatg ccctcaggtt
1681 acaggagctt gctgacactt gccccctaac actgaattgt gataggattg agaacaaagg
1741 taaagttttt gacagtgatg ctataattat caccactaac ttggccaacc cagcaccact
1801 ggactatgtc aactttgagg cgtgctcgag gcgcattgat ttcctcgtgt acgccgaagc
1861 ccctgatgtt gagaaggcga agcgcgactt cccaggccaa cctgatatgt ggaagaatgc
1921 cttcagccct gacttctctc acataaagct ggtgctggcc ccgcagggtg gctttgacaa
1981 gaacggcaac accccacatg ggaagggtgt catgaagacc cttaccatcg gttctctcat
2041 cgcccgtgct tcaggactcc tccatgaaag gctggatgag tacgagctac aaggcccagc
2101 cctcacaacc ttcaactttg accgaaacaa agtgctcgct ttcaggcagc ttgctgctga
2161 aaacaagtac gggttgatgg atacgatgag agttggaggg caactcaagg gcgtcagaac
2221 catgccagag ctcaagcaag cactcaagaa catctcaatt aagaagtgcc agatagtgta
2281 tggtggcagc acctacacac ttgaatctga tggcaagggt agtgtgaggg ttgacaaggt
2341 tcagagtgcc actgtgcaaa ccaacaacga actagccggc gccctgcatc atctcaggtg
2401 cgccagggtc aggtactatg tcaagtgtgt ccaggaagct ctgtactcca tcattcaaat
2461 tgcaggggct gcgtttgtca ccacgcgcat tgtcaagcgc atgaacatac aggatctatg
2521 gtctaagcca caactggagg acacggaaga agccactggc aaagacggat gcccaaaacc
2581 caaagatgat gaggagtttg ttgtttcatc cgacgacatc aaggttgagg gcaagaaagg
2641 gaagaacaag actggtcgcg gcaagaagca cacagccttc tcgagtaaag gtctcagtga
2701 tgaggagtac gacgagtaca aaagaatcag ggaggaaaga aacggcaagt actctataga
2761 ggaatacctc caagacagag acaagtatta cgaggaggtt gccatcgcca gggcgactga
2821 agaggatttc tgtgaagagg aagaggccaa gatccgacag agaatcttta gaccaacaag
2881 gaaacaacgc aaggaggaga gggcttctct cggtctagtc acaggctctg aaatcaggaa
2941 aagaaaccca gatgacttca aacccaaggg aaagttgtgg gccgatgacg acagaagtgt
3001 cgattacaac gagaagctca gttttgaagc cccaccaagc atctggtcaa ggatagtcaa
3061 ctttggttcg ggttggggtt tctgggtttc ccccagtctg ttcataacat caactcatgt
3121 tataccccag ggcacacagg agttcttcgg agtgtccatc aagcaaatcc agatacacaa
3181 atcaggcgaa ttctgccgcc tgaggttccc aaaaccaatc aggaccgatg tgacaggcat
3241 gatcttagag gagggtgccc ccgaaggcac cgtggccaca ctactcatca agagaccaac
3301 tggtgagctc atgcctttag cagccaggat gggcactcat gcaaccatga agatccaagg
3361 tcgcactgtt ggaggccaaa tgggtatgct cctgacaggg tccaatgcca aaagtatgga
3421 cctgggcacc acacctggcg actgtggttg tccctatatc tacaagagag ggaacgacta
3481 cgtggtcatc ggggttcata cggctgctgc ccgaggaggg aacactgtca tatgtgccac
3541 ccagggaagt gaaggtgagg ccacacttga gggcggtgac aacaaaggca cctactgtgg
3601 cgctccgatc ctaggtccag gaagtgcccc aaagctcagc accaaaacca aattctggag
3661 atcatccaca gcaccactcc cacctggcac ctatgaacca gcctacctcg gtggtaagga
3721 ccccagaatc aagggtggcc cctcactaca acaagttatg agggaccagt tgaaaccatt
3781 cacggaacca agaggcaaac aaccaaagcc aagtgtgttg gaagctgcca agagaaccat
3841 cattaacgtc cttgaacaaa caatagaccc acctcagaaa tggacgtttg cgcaagcttg
3901 cgcgtctctt gacaagacca cctccagtgg tcacccacac cacatacgga agaatgaatg
3961 ctggaatgga gattccttca caggcaagtt ggcagatcag gcctcaaagg ccaacttgat
4021 gtttgaggag gggaagaaca tgactccagt ttacacaggt gccctcaagg atgagttggt
4081 caaaactgac aagatatatg gcaagattaa gaagagactg ctttggggat cagacctggc
4141 aaccatgatc cggtgtgccc gggcgttcgg gggcctaatg gatgagctca aggcccactg
4201 tgtcacactt cctgtcagag ttggcatgaa catgaatgag gatggcccca tcatctttga
4261 aaagcattcc aggtatagat atcactatga tgcagactat tctagatggg actcaacaca
4321 acaaagagct atattggccg cagccctaga gatcatggtc aaattctccc cagagccaca
4381 cttagcccag atagttgcag aagaccttct atcccccagc gtgatggacg tgggtgattt
4441 caagatttca atcaacgagg gcctcccctc tggggtacct tgcacttcac aatggaactc
4501 tatcgcccac tggctcctca ccctctgtgc tctctctgaa gtcacggatc tctcccctga
4561 cattgttcag gccaactctc tcttctcttt ctatggtgat gatgaaattg tgagcacaga
4621 tataaaaatg gacccagaaa aactgacggc aaagctaaag gaatatggac tgaagccaac
4681 ccgccctgac aagactgaag gacctctaat catttctgag gatctaaatg gtttgacctt
4741 cctgcgaagg actgtaaccc gcgatccagc tggttggttt ggtaaattgg aacaaagctc
4801 aatactcagg cagatgtact ggaccagggg ccccaaccat gaggacccat ctgaaacaat
4861 gataccacat tcccaaaggc ccacgcagtt gatgtctttg ctgggtgagg ctgcactgca
4921 cggcccagca ttctacagca agatcagtaa actagtcatc acagagttaa aggaaggtgg
4981 catggatttt tacgtgccca gacaagagcc gatgttcagg tggatgagat tctcagatct
5041 gagcacgtgg gagggcgatc gcaatctggc tcccagtttt gtgaatgaag atggcgtcga
5101 gtgacgccaa cccatctgat gggtccgcag ccaacctcgt cccagaggtc aacaatgagg
5161 ttatggcttt ggagcctgtt gttggtgccg ccattgcagc acctgtagca ggccaacaaa
5221 atgtaattga cccctggatt agaaataatt ttgtacaagc ccctggtgga gagtttacag
5281 tgtcccctag aaacgctcca ggtgagatac tatggagcgc gcccttgggc cctgatttga
5341 acccctatct ttctcacctg tccagaatgt acaatggtta tgcaggtggt tttgaagtgc
5401 aagtaatcct cgcagggaac gcgttcactg ccgggaaagt catatttgca gcagttccac
5461 caaattttcc aactgaaggt ctaagcccca gccaggttac tatgttcccc catataattg
5521 tagatgttag gcaactggaa cctgtattga tccccctacc tgatgttagg aataatttct
5581 atcattataa tcaagcacat gattctaccc taaaattgat agcaatgttg tatacaccac
5641 tcagagctaa taatgccgga gatgatgtct ttacagtctc ttgtcgagtc ctcacgagac
5701 catcccccga ttttgatttt atattcctgg tgccacccac agttgaatca agaactaaac
5761 catttactgt cccaatctta actgttgagg aaatgtccaa ttcaagattc cccattcctt
5821 tggaaaagct gtacacgggt cctagcagtg cttttgttgt ccaaccacaa aatggcagat
5881 gcacgactga tggcgtgctc ttaggcacta ctcagctgtc agctgtcaat atctgcaact
5941 tcagggggga tgtcacccgt gttgggatca gccatgatta tacaatgaat ttggtgtccc
6001 aaaattggaa taattatgac ccaacagaag aaattccagc tcccctggga acgccagact
6061 ttgtgggaaa gatccaaggt ttgctcaccc aaaccacaag agcggacggt tcgacccgcg
6121 cccacaaagc tacagtgagc actgggagtg tccacttcac tccaaagctg ggtagtgttc
6181 aattcaccac cgatacgaac aatgatttcc aaactggcca aaacacaaaa tttaccccag
6241 ttggtgtcat ccaagacggt gatcaccatc agaatgaacc ccaacaatgg gtactcccaa
6301 attactcagg cacatctggt cacaatgtgc atctggcccc tgccgttgcc cccactttcc
6361 cgggtgagca gcttcttttc tttaggtcca ctatgcccgg gtgtagcggg taccccaaca
6421 tgaatttgga ttgcctactc ccccaggagt gggtgctgca cttttaccag gaagcagccc
6481 cagcacaatc cgatgtggct ctgttgagat ttgtgaatcc agacacaggt agggttctgt
6541 ttgagtgcaa actccataaa tcaggctata tcacagtggc tcacaccggc ccgtatgatt
6601 tggttatccc ccccaatggt tacttcagat ttgattcttg ggtcaaccag ttctacacac
6661 tcgcccccat gggaaatgga acggggcgca ggcgtgcatt ataatggctg gacctttctt
6721 tgctggattg gcatctgatg tcctcggttc cggacttggt tctctaatca atgctggagc
6781 tggagccatc aatcaaaaag ttgaatttga aaacaataga aaattacaac aagcttcttt
6841 tcaattcagt agtaatctgc aacaggcttc cttccaacat gataaggaga tgctccaagc
6901 acaaattgag gctactcaaa aattgcaaca aggtttgatg aaggttaaac aggcggtgct
6961 cttagagggt gggttttcca caacagatgc ggcccgtggg gcaatcaacg cccccatgac
7021 aaaggctctg gactggagcg gaacaaggta ctgggccccc gatgccaggg tcacaacata
7081 caatgcaggc cgcttctcca cccctcagcc tttgggggca ttacctggaa ggaccaatcc
7141 tagggttcct gctcctgctc ggagctcccc cagttcactt tccaatgctc ctactgccac
7201 ttctgtgtat tcaaatcaaa ctgtttcaac gagactaggt tcttcagctg gttctggtgc
7261 cggtgtctcg agtctcccgt caactgcaag gactaggagc tgggttgagg accaaaacag
7321 gaatttgtca cctttcatga ggggggctct caacacatca tttgtcaccc ctccatctag
7381 tagatcctcc aaccaaggca cagtctcaac cgtgcctaaa gagattttgg actcctggac
7441 tggcgctttt aacacgcgca ggcagcctct cttcgcacac attcgtaagc gaggggagtc
7501 acgggtgtaa tgtgaaaaga caaaattgat tatctttctt ttctttaatg tcttttaaaa
7561 aaaaaaaaaa aaaaaaaaaa
//