Typing tool
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Typing tool
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Complete norovirus genomes
| FJ537137 | GII.4 Den Haag | |
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| GII.P12 |
ORF1: 5..5104
ORF2: 5085..6704
ORF3: 6704..7510
LOCUS FJ537137 7580 bp RNA linear VRL 02-NOV-2009
DEFINITION Norovirus Hu/GII.4/CHDC4108/1987/US, complete genome.
ACCESSION FJ537137
VERSION FJ537137.1
KEYWORDS .
SOURCE Norovirus Hu/GII.4/CHDC4108/1987/US
ORGANISM Norovirus Hu/GII.4/CHDC4108/1987/US
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7580)
AUTHORS Bok,K., Abente,E.J., Realpe-Quintero,M., Mitra,T., Sosnovtsev,S.V.,
Kapikian,A.Z. and Green,K.Y.
TITLE Evolutionary dynamics of GII.4 noroviruses over a 34-year period
JOURNAL J. Virol. 83 (22), 11890-11901 (2009)
PUBMED 19759138
REFERENCE 2 (bases 1 to 7580)
AUTHORS Bok,K., Abente,E.J., Realpe-Quintero,M., Mitra,T., Sosnovtsev,S.V.,
Kapikian,A.Z. and Green,K.Y.
TITLE Direct Submission
JOURNAL Submitted (10-DEC-2008) Laboratory of Infectious Diseases,
Epidemiology Section, Norovirus Gastroenteritis Unit, National
Institute of Allergy and Infectious Diseases, National Institutes
of Health, 50 South Drive, BLD 50, Room 6316, Bethesda, MD 20892,
USA
FEATURES Location/Qualifiers
source 1..7580
/organism="Norovirus Hu/GII.4/CHDC4108/1987/US"
/mol_type="genomic RNA"
/strain="Hu/GII.4/CHDC4108/1987/US"
/host="Homo sapiens"
/db_xref="taxon:660658"
/country="USA"
/collection_date="1987"
/note="genotype: GII.4"
CDS 5..5104
/note="ORF-1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="ACT76147.1"
/translation="MKMASNDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARP
KQPPPRETPQRPPRPPTPELVKKIPPPPPNGEDELVVSYSVKDGVSGLPELSTVRQPD
EANTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LAKVELTPLSLFWRPVYTPQYLISPDTLKRLHGESFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCALSSLFTRPIKDIIGK
LRPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVVMISGKPGIGKTHLAREL
AKRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPEVEK
AKRDFPGQPDMWKNAFSPDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEYELQGPTLTTFNFDRNKVLAFRQLAAENKYGLVDTMKVGRQLKDVRTM
PELKQALKNISIKRCQIVYSGCTYTLESDGKGNVKVDRVQSATVQTNNELAGVLHHLR
CARIRYYVKCAQEALYSIIQIAGAAFVTTRIVKRMNIQDLWSKPQVEDTEETTNKDGC
PKPKDDEEFVVSSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNERLNFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAQEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRENDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQIMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPQRWSFTQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFERHSRYTYHYDADYSRWD
STQQRAVLAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFKISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
CDS 5085..6704
/note="structural protein; ORF-2"
/codon_start=1
/product="VP1"
/protein_id="ACT76148.1"
/translation="MKMASNDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLSRMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQAHDSTLKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMSNSRFPIPLEKLYTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSAVNICNFRGDVTHIVGSHDYTMNLVSQNWSNYDPTEEIPAPLGTPDFVGKIQGLL
TQTTRADGSTRAHKATVSTGSVHFIPKLGSVQFTTDTNNDFQTGQNTKFTPVGVIQDG
DHHQNEPQQWVLPNYSGRTGHNVHLAPAVAPTFPGEQLLFFRSTVPGCSGYPNMNLDC
LLPQEWVSHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYITVAHTGPYDLVL
PPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6704..7510
/note="structural protein; ORF-3"
/codon_start=1
/product="VP2"
/protein_id="ACT76149.1"
/translation="MAGSFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATQKLQQELMKVKQAVLLEGGFSTADAARGAIN
APMTKALDWSGTRYWAPDARVTTYNAGRFSTPQPSGALPGRMNPRVPAPARSPPSVLS
NAPTATSVYSNQTVSTRLGSSAGSGTGVSSLPSTARTRNWVEDQNRNLSPFMRGALNT
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRIRGESRV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgctgccgct gttgccaaca gcaacaacga
61 caccgcaaaa tcttcaagtg acggagtgct ttctagcatg gctgtcactt ttaaacgagc
121 cctcggggcg cggcctaaac agcctccccc gagggaaaca ccacaaagac ccccacgacc
181 acccacccca gaactggtca aaaagatccc ccctcccccg cccaacgggg aggatgaact
241 agtggtttct tatagtgtca aagatggcgt ttccggcctg cctgagcttt ccactgtcag
301 gcaaccggat gaagccaaca cggccttcag tgtcccccca ctcaatcaga gggagaatag
361 ggatgccaag gagccactaa ctggaacaat tctggaaatg tgggacggag agatctacca
421 ttacggccta tatgtggaac gaggtcttgt acttggtgtg cacaaaccac cagctgccat
481 cagcctcgcc aaggtcgaac taacaccact ctccttgttc tggagacctg tatacactcc
541 ccagtatctc atctccccag acactctcaa gagactgcac ggagaatcgt tcccctatac
601 agcctttgac aacaattgct atgccttctg ttgttgggtc ttagacctaa acgactcgtg
661 gctgagtagg cgaatgatcc agagaacaac tggtttcttc aggccctacc aagattggaa
721 caggaaaccc ctccctacta tggatgactc caaattaaag aaggtagcta acatattcct
781 gtgtgctcta tcttcactat tcaccaggcc catcaaagac ataataggga agctgagacc
841 tcttaacatt ctcaacatcc tggcctcatg tgattggact tttgcaggca tagtggaatc
901 cttgatactc ttggcagagc tctttggagt tttctggaca cccccagatg tgtctgcgat
961 gattgccccc ttactaggtg attacgagct acaggggcct gaggaccttg cagtggaact
1021 cgttccaata gtgatggggg gaattggttt ggtgctggga tttaccaaag agaagattgg
1081 gaagatgctg tcatctgctg catccacctt aagagcttgt aaagatcttg gtgcatacgg
1141 gctggaaatc ctaaaattag tcatgaagtg gttcttccca aagaaagagg aggcaaatga
1201 gctggctatg gtaagatcca tcgaggatgc ggtgttggac ctcgaggcaa ttgaaaacaa
1261 ccatatgacc accctgctca aagacaaaga cagtctggca acctatatga gaacccttga
1321 ccttgaggag gagaaagcca ggaagctctc aaccaagtct gcttcacctg acatcgtggg
1381 cacaatcaac gctctcctgg cgagaattgc tgctgcacgt tccctggtgc atcgagcgaa
1441 ggaggagctt tccagcagac caagacctgt tgttgtgatg atatcaggca aaccagggat
1501 agggaagacc caccttgcca gggaactggc caagagaatc gcagcttccc tcacagggga
1561 ccagcgtgta ggtctcatcc cacgcaatgg cgtcgaccac tgggacgcgt acaaggggga
1621 gagggtcgtt ctatgggacg actatggaat gagcaatccc atccatgatg ccctcaggtt
1681 acaagagctc gctgatactt gccccctcac gctaaactgt gacaggatcg agaacaaagg
1741 aaaggtcttt gacagtgatg ccataattat cactaccaat ctggccaacc cagcgccact
1801 ggactatgtc aactttgaag catgctcgag gcgcatcgat ttcctcgtgt atgcagatgc
1861 ccctgaagtc gaaaaggcga aacgtgattt tccaggccaa cctgacatgt ggaagaacgc
1921 tttcagtcct gatttctcgc acataaaact ggcgctggct ccacagggtg gctttgacaa
1981 gaatggaaat accccacatg ggaagggcgt catgaagact ctcaccactg gctctctcat
2041 tgcccgagca tcagggctac tccatgagag gttggatgag tacgagctgc agggcccaac
2101 tctcaccact ttcaactttg atcgcaacaa ggtgcttgcc tttaggcagc ttgctgctga
2161 gaacaaatac gggctggtgg acacaatgaa agttggaaga cagctcaagg atgtcagaac
2221 catgccagag cttaaacaag cactcaagaa tatctcaatc aagagatgcc agatagtgta
2281 cagtggttgc acctacacac ttgagtctga tggcaagggc aatgtaaaag ttgacagagt
2341 tcagagtgcc accgtgcaga ccaacaacga gctggccggt gtcctacacc acctgaggtg
2401 tgccagaatt agatattatg tcaagtgtgc ccaggaggcc ctgtattcca tcattcaaat
2461 tgccggagct gcatttgtca ccacgcgcat cgtcaagcgc atgaacatac aagacctctg
2521 gtccaagcca caggtggaag acacagagga gactaccaac aaggatgggt gccccaaacc
2581 caaagatgat gaggagttcg tcgtctcatc cgacgacatc aaaactgagg gcaagaaagg
2641 gaagaacaag actggccgtg gcaagaagca cacagccttt tcaagtaaag gtctcagtga
2701 tgaagaatac gatgagtaca aaaggatcag ggaagaaagg aacggcaagt actccataga
2761 agagtacctt caggacaggg acaagtacta tgaggaggta gccattgcca gggcgaccga
2821 ggaggacttc tgtgaagagg aagaggccaa gattcggcaa aggattttta ggccaacaag
2881 gaaacaacgc aaggaggaga gggcctctct cggtttagtc acaggctctg aaatcaggaa
2941 gaggaaccca gatgatttca agcctaaagg aaagctgtgg gctgatgacg acaggagtgt
3001 tgactacaat gagagactca attttgaggc cccaccaagc atctggtcga ggatagtcaa
3061 ctttggttca ggttggggct tttgggtttc tcccagcctg ttcataacat caactcatgt
3121 cataccccag ggcgcacagg agtttttcgg agtccccatc aaacaaattc agatacacaa
3181 atcgggcgaa ttctgtcgct tgaggttccc aaaaccgatc aggactgatg tgacgggcat
3241 gatcttagaa gaaggtgcgc ccgaaggcac cgtggccaca ctactcatca agaggccaac
3301 tggagaactt atgcccttag cagccagaat gggaacccat gcaaccatga aaattcaagg
3361 gcgcactgtt ggaggccaaa tgggcatgct tctgacagga tccaacgcca aaagtatgga
3421 tctaggcacc acaccaggtg actgtggctg tccctacatc tacaagaggg aaaatgacta
3481 tgtggttatt ggagtccaca cggctgccgc tcgtggagga aacactgtca tatgtgccac
3541 ccaagggagt gagggagaag ccacacttga aggcggtgac aataagggaa cctactgtgg
3601 tgcaccaatc ctaggtccag gaagtgcccc aaaactcagc accaagacta aattctggag
3661 atcatccaca acaccactcc cacctggcac ctatgaacca gcctaccttg gtggtaagga
3721 ccccagagtc aagggcggcc cttcattgca acaaattatg agggaccagc tgaaaccatt
3781 cacagagccc aggggcaaac caccaaagcc aagtgtgtta gaggctgcca agaaaaccat
3841 catcaatgtc cttgaacaaa caattgatcc acctcagagg tggtcattca cgcaagcctg
3901 cgcgtccctc gacaagacta cttccagtgg ccatccgcac cacatgcgga aaaacgactg
3961 ctggaacggg gaatccttca caggcaagct ggcagatcag gcttccaagg ccaacttgat
4021 gttcgaagag gggaagaaca tgaccccagt ttacacaggt gcgcttaagg atgagctggt
4081 caaaactgac aaaatttatg gtaagatcaa gaagaggctc ctctggggct cagacttagc
4141 gaccatgatc cggtgcgcta gagcattcgg gggcctgatg gatgaactca aggctcactg
4201 tgttacactt cctgtcagag ttggtatgaa tatgaatgaa gatggcccca tcatcttcga
4261 gagacactcc agatatacat atcactatga tgccgattac tctcggtggg attcaacaca
4321 acaaagggcc gtgctagcag cagccctaga aatcatggtt aaattctccc cagaaccgca
4381 tctggcccag atagttgcag aagaccttct ctcccctagt gtgatggatg tgggtgactt
4441 caaaatatca atcaatgagg gcctcccctc tggagtaccc tgcacttctc aatggaattc
4501 catcgcccac tggctcctca ccctctgtgc actctctgaa gttacaaatc tgtcccctga
4561 cattattcag gctaattccc tcttctcctt ttacggtgat gatgaaattg tcagtacaga
4621 tataaagttg gacccagaga aactgacagc aaagctcaag gaatacggat tgaaaccaac
4681 ccgccctgat aaaactgagg ggccccttgt tatctctgaa gacttgaatg gtctaacctt
4741 cctgcggaga actgtgaccc gcgatccagc tggctggttt ggaaaattgg atcagagctc
4801 aatacttagg caaatgtact ggactagagg ccccaaccat gaagacccat ctgaaacaat
4861 gataccacac tcccaaagac ccatacaatt aatgtcttta ctgggcgagg ccgcactcca
4921 cggcccagca ttctatagca aaattagcaa gctagtcatt gcagagctga aggaaggtgg
4981 catggatttt tacgtgccca gacaagagcc aatgttcaga tggatgagat tctcagatct
5041 gagcacgtgg gagggcgatc gcaatctggc tcccagtttt gtgaatgaag atggcgtcga
5101 atgacgccaa cccatctgat gggtccgcag ccaacctcgt cccagaggtc aacaatgagg
5161 ttatggctct ggagcccgtt gttggtgccg ctattgcggc acctgtagcg ggccaacaaa
5221 atgtaattga tccctggatt agaaataatt ttgtacaagc ccctggtgga gagttcacag
5281 tgtcccctag aaacgctcca ggtgagatac tatggagcgc gcccttgggc cccgatttga
5341 atccctatct ttcccatttg tccagaatgt acaatggtta tgcaggtggt tttgaagtgc
5401 aagtaatcct cgcggggaac gcgttcaccg ccgggaaagt catatttgca gcagttccac
5461 caaactttcc aactgaaggc ctaagcccca gccaggttac tatgttcccc catataattg
5521 tagatgttag gcaattggaa cctgtgttaa tccccctacc tgatgttagg aataatttct
5581 accactacaa tcaagcacat gattctacac ttaagttgat agcaatgttg tacacaccac
5641 tcagagctaa taatgccggg gatgacgtct tcacagtctc ttgtcgagtt cttacgaggc
5701 catcccccga ttttgatttt atattcctgg tgccacccac agttgaatca agaactaaac
5761 cattcactgt cccaatttta actgttgagg aaatgtctaa ttcaagattt cccattcctt
5821 tagaaaagct atacacgggt cctagcagtg cttttgttgt ccaaccacaa aatggcagat
5881 gtacgactga tggcgtactc ttaggcacta cccagctgtc agctgtcaat atctgtaact
5941 tcagggggga tgtcacccat attgtgggta gccatgacta tacaatgaat ttggtatccc
6001 aaaattggag caattatgac ccaacagaag aaatcccagc ccccctggga acgccagatt
6061 ttgtgggaaa gatccaaggc ttactcaccc agaccacaag agcggacggc tcgacccgtg
6121 cccacaaagc tacagtgagc actgggagtg tccacttcat tccaaagctg ggtagtgtcc
6181 aattcaccac ggacacgaat aatgacttcc aaactggcca aaacacaaaa ttcaccccag
6241 ttggtgtcat ccaagacggt gatcaccatc agaatgaacc ccaacaatgg gtactcccaa
6301 attactcagg tagaactggt cataatgtgc atctggcccc tgccgtcgcc cccacttttc
6361 cgggcgagca gcttcttttc tttagatcca ctgtgcccgg ttgtagcggg taccccaaca
6421 tgaatctgga ttgcctactc cctcaggaat gggtgtcgca cttttaccag gaagcagctc
6481 cagcacaatc cgatgtggct ctgctgagat ttgtgaatcc agatacaggt agggttctgt
6541 ttgagtgcaa gctccataaa tcaggctata tcacagtggc tcacaccggc ccgtatgatt
6601 tggttctccc ccccaatggt tatttcagat ttgattcttg ggtcaaccag ttctacacac
6661 tcgcccccat gggaaatgga acggggcgta ggcgtgcatt ataatggctg gatctttctt
6721 tgctggattg gcatctgatg tcctcggctc tggacttggt tctctaatca atgctggagc
6781 tggagccatc aatcaaaaag ttgaatttga aaacaataga aaattacaac aagcttcctt
6841 ccaatttagt agtaatctac aacaggcttc cttccaacat gataaggaga tgctccaagc
6901 acaaattgag gctactcaga aattgcaaca agaactgatg aaggttaaac aggcagtgct
6961 tctagagggt ggattttcca cagcagacgc ggcccgcggg gcaatcaacg cccccatgac
7021 aaaggctctg gactggagcg ggacaaggta ctgggccccc gatgccaggg tcacaacata
7081 caatgcaggc cgcttttcca cccctcagcc ttcgggggca ttgccaggaa ggatgaatcc
7141 tagggtcccc gctcctgctc ggagtccccc cagtgtgctt tctaatgctc ctactgctac
7201 ttctgtgtat tcaaatcaaa ctgtctcaac gagactaggt tcttcagctg gttctggtac
7261 tggtgtctcg agtctcccgt caactgcaag gactaggaat tgggttgagg accaaaacag
7321 gaatttgtca cctttcatga ggggggctct caacacatca ttcgtcaccc ctccatctag
7381 tagatcctcc agccaaggca cagtctcaac cgtgcctaaa gaaattttgg actcctggac
7441 tggcgctttc aacacgcgca ggcagcctct cttcgctcac attcgtatac gaggggagtc
7501 acgggtgtaa tgtgaaaaga caaaattgat tatctttcct ttctttagtg tcttttaaaa
7561 aaaaaaaaaa aaaaaaaaaa
//