Typing tool
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Typing tool
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Complete norovirus genomes
| FJ537136 | GII.4 | |
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| GII.P12 |
ORF1: 5..5104
ORF2: 5085..6704
ORF3: 6704..7510
LOCUS FJ537136 7580 bp RNA linear VRL 02-NOV-2009
DEFINITION Norovirus Hu/GII.4/CHDC3967/1988/US, complete genome.
ACCESSION FJ537136
VERSION FJ537136.1
KEYWORDS .
SOURCE Norovirus Hu/GII.4/CHDC3967/1988/US
ORGANISM Norovirus Hu/GII.4/CHDC3967/1988/US
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7580)
AUTHORS Bok,K., Abente,E.J., Realpe-Quintero,M., Mitra,T., Sosnovtsev,S.V.,
Kapikian,A.Z. and Green,K.Y.
TITLE Evolutionary dynamics of GII.4 noroviruses over a 34-year period
JOURNAL J. Virol. 83 (22), 11890-11901 (2009)
PUBMED 19759138
REFERENCE 2 (bases 1 to 7580)
AUTHORS Bok,K., Abente,E.J., Realpe-Quintero,M., Mitra,T., Sosnovtsev,S.V.,
Kapikian,A.Z. and Green,K.Y.
TITLE Direct Submission
JOURNAL Submitted (10-DEC-2008) Laboratory of Infectious Diseases,
Epidemiology Section, Norovirus Gastroenteritis Unit, National
Institute of Allergy and Infectious Diseases, National Institutes
of Health, 50 South Drive, BLD 50, Room 6316, Bethesda, MD 20892,
USA
FEATURES Location/Qualifiers
source 1..7580
/organism="Norovirus Hu/GII.4/CHDC3967/1988/US"
/mol_type="genomic RNA"
/strain="Hu/GII.4/CHDC3967/1988/US"
/host="Homo sapiens"
/db_xref="taxon:660657"
/country="USA"
/collection_date="1988"
/note="genotype: GII.4"
CDS 5..5104
/note="ORF-1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="ACT76144.1"
/translation="MKMASNDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARP
KQPPPREIPQRPPRPPTPELVKKIPPPPPNGEDELVVSYSVKDGVSGLPELSTVRQPD
EANTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LAKVELTPLSLFWRPVYTPQYLISPDTLKRLHGESFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCALSSLFTRPIKDIIGK
LRPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLAREL
AKRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPEVEK
AKRDFPGQPDMWKNAFSPDFSHIKLTLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEYELQGPTLTIFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVRTM
PELKQALKNISIKRCQIVYSGCTYTLESDGKGSVKVDRVQSATVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIVKRMNIQDLWSKPQVEDTEETTSKDGC
PKPKDDEEFVVSSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNERLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAQEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRENDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLRPFTEP
RGKPPKPSVLEAAKKTIVNVLEQTIDPPQKWSFTQACASLDKTTSSGHPHHIRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFERHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFKISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEITNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
CDS 5085..6704
/note="structural protein; ORF-2"
/codon_start=1
/product="VP1"
/protein_id="ACT76145.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNIIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLSRMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSHDSTLKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMSNSRFPIPLEKLYTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSAVNICNFRGDVTHIVGSHDYTMNLVSQNWSNYDPTEEIPAPLGTPDFVGKIQGLL
TQTTRADGSTRAHKATVSTGSVHFTPKLGSVQFTTDTNNDFQTGQNTKFTPVGVIQDG
DHHQNEPQQWVLPNYSGRTGHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMNLDC
LLPQEWVLHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYITVAHTGPYDLVI
PPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6704..7510
/note="structural protein; ORF-3"
/codon_start=1
/product="VP2"
/protein_id="ACT76146.1"
/translation="MAGSFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATQKLQQDLMKVKQAVLLEGGFSTTDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRTNPRVPVLSRGPPSTLS
NASTATSVYSNQTVSTRLGSSAGSGTSVSSLPSTARTRNWVEDQNRNLSPFMRGALNT
SFVTPPSSRSSNQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgctgccgct gttgccaaca gcaacaacga
61 caccgcaaaa tcttcaagtg acggagtgct ttctagcatg gctgtcactt ttaaacgagc
121 cctcggggcg cggcctaaac agcctccccc gagggaaata ccacaaagac ccccacgacc
181 acccacccca gaattggtca aaaagatccc ccctcccccg cccaacgggg aggatgaact
241 agtggtttct tatagtgtca aagatggcgt ttccggtctg cctgagcttt ccactgtcag
301 gcaaccggat gaagccaata cggccttcag tgttccccca ctcaaccaga gggagaatag
361 ggatgccaag gagccactaa ctggaacaat tctggaaatg tgggatggag agatctacca
421 ttatggccta tatgtggagc gaggtcttgt acttggcgtg cacaaaccac cagctgccat
481 cagcctcgcc aaggtcgaac taacaccact ctccttgttt tggagacctg tatacacccc
541 ccagtacctc atctccccag acactctcaa gagattgcac ggagaatcgt tcccctatac
601 agcctttgac aacaattgct atgccttctg ttgctgggtc ttagacttaa acgactcgtg
661 gctgagtagg agaatgatcc agagaacaac tggtttcttt agaccctacc aagattggaa
721 taggaaaccc ctccctacta tggatgactc caaattaaag aaggtagcta acatattcct
781 gtgtgctcta tcttcactgt tcaccaggcc catcaaagac ataataggga aactaagacc
841 tcttaacatc ctcaacatct tagcctcatg tgattggact tttgcaggta tagtggaatc
901 cttgatactc ttggcagagc tctttggagt tttctggaca cccccagatg tgtctgcgat
961 gattgccccc ttgctgggtg attacgagtt acagggccct gaggaccttg cagtggaact
1021 cgttccaata gtgatggggg gaattggttt ggtactagga ttcaccaaag agaagattgg
1081 gaagatgttg tcatctgctg catccacctt aagagcctgt aaagatcttg gtgcatacgg
1141 gctggaaatc ctaaaattag tcatgaagtg gttcttccca aagaaagagg aagcaaatga
1201 gctggctatg gtgagatcca tcgaggatgc ggtgctggac ctcgaggcaa ttgaaaacaa
1261 ccacatgacc accctgctca aagataaaga cagcctggca acctatatga gaacccttga
1321 ccttgaggag gagaaagcca ggaagctctc aaccaagtct gcttcacctg atatcgtggg
1381 cacaatcaac gcccttctgg cgagaatcgc tgctgcacgt tccctggtgc atcgagcgaa
1441 ggaggagctt tccagcagac caagacctgt tgttgtgatg atatcaggca gaccagggat
1501 agggaagacc caccttgcca gggagctggc caagagaatc gcagcttccc tcacaggaga
1561 ccagcgtgtg ggtctcatcc cacgcaatgg cgtcgaccac tgggacgcat acaaggggga
1621 aagggtcgtc ctatgggacg actatggaat gagtaatccc atccatgacg cccttaggtt
1681 acaagaactc gctgacactt gccccctcac tctaaactgt gacaggattg agaacaaagg
1741 aaaggtcttt gacagtgacg ctataattat caccactaat ctggccaacc cagcaccatt
1801 ggactatgtc aactttgaag catgctcgag gcgcatcgat ttcctcgtgt atgcagatgc
1861 ccctgaagtc gagaaggcga aacgtgattt tccaggccaa cctgacatgt ggaagaacgc
1921 tttcagtcct gatttctcgc acataaaact aactctggct ccacagggtg gcttcgacaa
1981 gaatggaaac accccacatg ggaagggcgt catgaagact ctcaccactg gctccctcat
2041 tgcccgagca tcagggctac tccatgagag attagatgag tatgagctgc agggcccaac
2101 tctcaccatt ttcaactttg atcgcaacaa ggtgcttgct tttaggcagc ttgctgctga
2161 aaataaatac gggctgatgg acacaatgaa agttggaaga cagctcaagg atgtcagaac
2221 catgccagag ctcaaacaag cactcaagaa tatttcaatc aagaggtgcc agatagtgta
2281 cagtggatgc acctatacac ttgagtctga tggcaagggc agtgtgaaag ttgacagagt
2341 tcagagcgct accgtgcaga ccaacaacga gctggccggt gccctacacc atctaaggtg
2401 tgccagaatt agatactatg tcaagtgtgt ccaggaggcc ctgtattcca tcatccaaat
2461 tgctggagct gcatttgtca ccacgcgcat cgtcaagcgc atgaatatac aagacctctg
2521 gtccaagcca caagtagaag acacagagga gactaccagc aaggacgggt gcccaaaacc
2581 caaagacgat gaggagttcg tcgtctcatc cgacgacatc aaaactgagg gcaagaaagg
2641 gaagaacaag actggccgtg gcaagaagca cacagccttc tcaagcaaag gtctaagtga
2701 tgaagagtac gatgagtaca agaggatcag agaagaaaga aacggtaagt actccataga
2761 agagtacctt caggaccggg acaagtacta tgaggaggtg gccattgcca gggcgaccga
2821 ggaggacttc tgtgaagagg aggaggccaa gattcggcag aggattttca ggccaacaag
2881 gaaacaacgc aaggaggaga gggcctctct cggtttagtc acaggctctg aaatcaggaa
2941 gaggaaccca gatgatttca agcccaaggg aaaactgtgg gctgatgacg acaggagcgt
3001 agactacaat gagagactca gttttgaggc cccaccaagc atctggtcga ggatagtcaa
3061 ctttggttca ggttggggct tttgggtttc tcccagcctg ttcataacat caactcatgt
3121 cataccccag ggcgcacagg agttcttcgg agtccccatc aaacaaattc agatacacaa
3181 atcgggcgaa ttctgtcgct tgaggttccc aaaaccaatc aggactgatg tgacgggcat
3241 gatcttagaa gaaggtgcgc ccgaaggcac cgtggccaca ctactcatca agaggccaac
3301 tggagaactt atgcccttag cagccagaat ggggacccat gcaaccatga agattcaagg
3361 acgcactgtt gggggccaaa tgggcatgct cctgacagga tccaacgcca aaagtatgga
3421 cctaggcact acaccaggtg actgtggctg tccctacatc tacaagaggg aaaatgacta
3481 cgtggttatt ggagtccaca cggctgccgc tcgtgggggt aacactgtta tatgtgccac
3541 ccaggggagt gaaggagagg ctacacttga aggcggtgac agtaagggaa cctactgtgg
3601 tgcaccaatc ctaggcccag gaagtgcccc aaaactcagc accaagacta aattctggag
3661 atcatctaca acaccactcc cacctggcac ctatgaacca gcctaccttg gtggtaagga
3721 ccccagggtc aagggtggcc cttcattgca acaagttatg agggaccagc tgagaccatt
3781 tacagaaccc aggggcaaac caccaaagcc aagtgtgttg gaggctgcca agaaaaccat
3841 cgtcaatgtc cttgaacaaa caattgatcc acctcagaaa tggtcattca cgcaagcttg
3901 cgcgtccctc gacaagacta cttccagtgg ccacccgcac cacatacgga aaaatgactg
3961 ctggaacggg gaatccttca caggtaagtt ggcagaccag gcttccaagg ccaacctgat
4021 gttcgaagag gggaagaaca tgaccccagt ttacacaggt gcgctcaagg atgagctggt
4081 caaaactgac aaaatttatg gcaagatcaa gaagaggctt ctctggggct cggacttagc
4141 gaccatgatc cggtgcgctc gagcattcgg aggcctaatg gatgaactca aggcacactg
4201 tgttacacta cctgtcagag ttggcatgaa catgaatgag gatggcccca tcatctttga
4261 gaggcattcc agatacaaat accactatga tgctgattac tctcggtggg attcaacaca
4321 acagagggcc gtattagcag cagccctaga aatcatggtt aaattctccc cagaaccaca
4381 tctggcccag atagttgcag aagaccttct ctctcctagt gtgatggatg tgggtgactt
4441 caaaatatca atcaatgagg gcctcccctc tggggtgccc tgcacctccc aatggaattc
4501 catcgcccac tggctcctca ctctctgtgc actctccgaa atcacaaact tgtcccctga
4561 cattatacag gctaattccc tcttctcctt ttatggtgat gatgaaattg tcagtacaga
4621 tataaagttg gacccagaga aattgacagc aaaactcaag gaatacgggt tgaaaccaac
4681 ccgccctgac aagactgagg gaccccttgt tatctctgaa gacttgaatg gtctgacctt
4741 cctgcggagg actgtgaccc gcgacccagc tggctggttt ggaaaattgg aacagagctc
4801 aatacttagg caaatgtact ggactagggg ccccaaccat gaagacccat ctgaaacaat
4861 gataccacac tcccaaagac ccatacaact aatgtcttta ctgggcgagg ccgcactcca
4921 cggcccggca ttctacagca aaattagcaa gctagtcatt gcagagctga aggaaggtgg
4981 catggatttt tacgtgccca ggcaagaacc aatgttcaga tggatgagat tctcagatct
5041 gagcacgtgg gagggcgatc gcaatctggc tcccagtttt gtgaatgaag atggcgtcga
5101 gtgacgccaa cccatctgat gggtccgcag ccaacctcgt cccagaggtc aacaatgagg
5161 ttatggctct ggagcccgtt gttggtgctg ctattgcagc acctgtagcg ggccaacaaa
5221 atataattga cccctggatt agaaacaatt ttgtacaagc ccctggtggt gagtttacag
5281 tgtcccctag aaacgctcca ggtgagatac tatggagcgc gcccttgggc cctgatttga
5341 acccctatct ttctcatctg tccagaatgt acaatggtta tgcaggtggt tttgaagtgc
5401 aagtaattct cgcggggaac gcgttcaccg ccgggaaagt tatatttgcg gcagttccac
5461 caaactttcc aactgaaggc ttaagcccca gccaggtcac tatgttcccc catataattg
5521 tagatgttag gcaattggaa cctgtgttga tccccctacc tgatgttagg aataatttct
5581 atcattataa tcaatcacat gattctaccc ttaagctgat agcaatgttg tatacaccac
5641 tcagagctaa taatgccggg gatgatgtct tcacagtctc ttgtcgagtt ctcacgaggc
5701 catcccccga ttttgatttt atattccttg tgccacccac agttgaatca agaaccaaac
5761 cattcactgt cccaatctta actgttgagg aaatgtctaa ttcaagattc cccattcctt
5821 tggaaaagtt atatacgggt cctagcagtg cttttgttgt ccaaccacaa aatggcagat
5881 gtacgactga tggcgtgctc ttaggcacta cccagctgtc agctgtcaat atctgtaact
5941 tcagggggga tgtcacccac attgtgggca gccatgatta tacaatgaat ctggtatccc
6001 aaaattggag caattatgac ccaacagaag aaatcccagc ccccctggga acaccagatt
6061 tcgtgggaaa gatccaaggc ctgctcaccc agaccacaag agcggatggc tcgacccgtg
6121 cccacaaggc tacagtgagc actgggagcg tccacttcac tccaaagctg ggtagtgttc
6181 aattcaccac tgacacaaac aatgatttcc aaactggcca aaacacgaaa ttcacaccag
6241 ttggcgtcat ccaagacggt gatcaccacc agaatgaacc ccaacaatgg gtgctcccaa
6301 attactcagg tagaactggt cataatgtgc acctggcccc tgccgttgcc cccacttttc
6361 cgggtgagca actccttttc ttcaggtcca ctatgcccgg atgtagcggg taccccaaca
6421 tgaacttgga ttgtctactc ccccaggaat gggtgctgca cttctaccag gaagcagctc
6481 cagcacaatc cgatgtggct ctgctgagat ttgtgaatcc agacacaggt agggtcctgt
6541 ttgagtgcaa gctccataag tcaggctata tcacagtggc tcacaccggc ccgtatgatt
6601 tggttatccc ccccaatggt tattttagat ttgattcctg ggtcaaccag ttctacacac
6661 ttgcccccat gggaaatgga acggggcgca ggcgtgcatt ataatggctg gatctttctt
6721 tgctggattg gcatctgacg tcctcggctc tggactcggt tctctaatca atgctggagc
6781 tggagccatc aatcaaaaag ttgaatttga aaacaacaga aaattacagc aagcttcctt
6841 ccaattcagt agtaacctac aacaggcttc cttccaacat gataaagaga tgctccaagc
6901 acagattgag gctactcaaa aattgcaaca agatctgatg aaggttaaac aggcagtgct
6961 cctagagggt ggattttcca caacagatgc agcccgtggg gcaatcaacg cccccatgac
7021 aaaggctctg gactggagcg gaacaaggta ctgggcccct gatgccagga ccacaacata
7081 caatgcaggc cgcttttcca cccctcagcc ttcgggagca ttgccaggaa gaactaatcc
7141 cagggttccc gttctctctc ggggcccccc cagtacactt tctaatgctt ctactgccac
7201 ttctgtgtat tcaaatcaaa ctgtttccac gagactaggt tcttcagctg gttctggtac
7261 tagtgtctcg agtctcccgt caactgcaag aactaggaac tgggttgagg accaaaacag
7321 gaatttgtca cctttcatga gaggggctct caacacgtca ttcgtcaccc ctccatctag
7381 tagatcctct aaccaaggca cagtctcaac cgtgcctaaa gaaattttgg actcctggac
7441 tggcgctttc aacacgcgca ggcagcctct cttcgctcac attcgcaagc gaggggagtc
7501 acgggtgtaa tgtgaaaaga caaaattgat tatctttctt ttctttagtg tcttttaaaa
7561 aaaaaaaaaa aaaaaaaaaa
//