Typing tool
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Typing tool
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Complete norovirus genomes
| FJ537135 | GII.4 | |
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| GII.PNA3 |
ORF1: 5..5104
ORF2: 5085..6704
ORF3: 6704..7510
LOCUS FJ537135 7576 bp RNA linear VRL 02-NOV-2009
DEFINITION Norovirus Hu/GII.4/CHDC2094/1974/US, complete genome.
ACCESSION FJ537135
VERSION FJ537135.1
KEYWORDS .
SOURCE Norovirus Hu/GII.4/CHDC2094/1974/US
ORGANISM Norovirus Hu/GII.4/CHDC2094/1974/US
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7576)
AUTHORS Bok,K., Abente,E.J., Realpe-Quintero,M., Mitra,T., Sosnovtsev,S.V.,
Kapikian,A.Z. and Green,K.Y.
TITLE Evolutionary dynamics of GII.4 noroviruses over a 34-year period
JOURNAL J. Virol. 83 (22), 11890-11901 (2009)
PUBMED 19759138
REFERENCE 2 (bases 1 to 7576)
AUTHORS Bok,K., Abente,E.J., Realpe-Quintero,M., Mitra,T., Sosnovtsev,S.V.,
Kapikian,A.Z. and Green,K.Y.
TITLE Direct Submission
JOURNAL Submitted (10-DEC-2008) Laboratory of Infectious Diseases,
Epidemiology Section, Norovirus Gastroenteritis Unit, National
Institute of Allergy and Infectious Diseases, National Institutes
of Health, 50 South Drive, BLD 50, Room 6316, Bethesda, MD 20892,
USA
FEATURES Location/Qualifiers
source 1..7576
/organism="Norovirus Hu/GII.4/CHDC2094/1974/US"
/mol_type="genomic RNA"
/strain="Hu/GII.4/CHDC2094/1974/US"
/host="Homo sapiens"
/db_xref="taxon:660656"
/country="USA"
/collection_date="1974"
/note="genotype: GII.4"
CDS 5..5104
/note="ORF-1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="ACT76141.1"
/translation="MKMASNDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARP
KQPPPREIPQRPPRPPTPELVKKIPPPPPNGEGEPVVSYSVKDGVSGLPELSTVRQPD
ETNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LAKVELAPLSLFWRPVYAPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCALSSLFTRPIKDIIGK
LRPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEASELAMVRSIEDAVLDLEAIENNHLTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVVMISGKPGIGKTHLAREL
AKKIATTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDVEK
AKRDFPGQPDMWKNAFSPDFSHIKLMLAPQGGFDKNGNTPHGKGVMKTLTIGSLIARA
SGLLHERLDEYELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGGQLKGVRTM
PELKQALKNISIKRCQIVYGGSTYTLESDGKGGVKVDRVQSTTVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIVKRMNIQDLWSKPQLENTEEAASKDGC
PKPKDDEEFVVSSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGTQEFFGVSIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVGIGVHTAAAHGENTVICATQGSEGEATLEGGDNKGAYCGAPILG
PGSAPKLSTKTKFWRSSTAPLPPGTYEPPYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKQPKPSVLEAAKRTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHIRKNECW
NGDSFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRPILAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFKISINEGLPFGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIQLDPEKLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
CDS 5085..6704
/note="structural protein; ORF-2"
/codon_start=1
/product="VP1"
/protein_id="ACT76142.1"
/translation="MKMASSDANPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNIIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLSPDLNPYLSHLSRMYNGYAGG
FEVQVILAGNAFTAGKIIFAAIPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQAHDSTLKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMSNSRFPIPLEKLYTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSAVNICNFRGDVTRVGISHDYTMNLVSQNWNNYDPTEEIPAPLGTPDFVGKIQGLL
TQTTRADGSTRAHKATVSTGSVHFTPKLGSVQFTTDTNNDFQTGQNTKFTPVGVIQDG
DHHQNEPQQWVLPNYSGTSGHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMNLDC
LLPQEWVSHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYITVAHTGPYDLVI
PPNGYFRFDSWVNQFYTLAPMGNGSGRKRVL"
CDS 6704..7510
/note="structural protein; ORF-3"
/codon_start=1
/product="VP2"
/protein_id="ACT76143.1"
/translation="MAGSFFAGLASDVLGSGLGSLINAGAGAINQRVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIDATQKLQQGLMQIKQAVLLEGGFSAADAARGAIN
APMTKTLDWSGTRYWAPEARVTTYNAGHFSPSQPSRTPSGRISSVTSASVRNSPSLSS
KSSTATTVYSNQTVSTRLGSSAGSGTSVSSLPSASRTRSWVEDQNRSVSPFMRGALNT
SFVTPPSSRSSNQSTVSTVPKEILDSWTGAFNTRRQPLFAYIHKRGESRV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgctgccgct gttgctaaca gcaacaacga
61 caccgcaaaa tcttcaagtg acggagtact ttctagtatg gctgtcactt ttaaacgagc
121 cctcggggcg cggcctaagc agccgccccc gagggagata ccacaaagac ccccacgacc
181 gcccactccg gagttggtca agaaaatccc tccccccccg cccaacgggg agggtgagcc
241 agtggtctct tacagtgtca aagatggcgt ttccgggttg cctgagctct ccactgtcag
301 gcaaccagat gagaccaaca cggcatttag tgttccccca ctcaaccaga gagagaacag
361 ggatgccaag gagccactga ctggaacaat cctggagatg tgggacgggg aaatctacca
421 ttatggcttg tacgttgaac gaggcctggt gcttggcgtg cacaaaccac cagcagccat
481 tagccttgcc aaggttgaat tggcaccact ttctttgttc tggagacctg tgtacgcccc
541 ccagtatctc atctccccag acactctcag gagactgcat ggggaatcat tcccctacac
601 agcctttgac aacaactgct atgccttctg ttgctgggtt ttagacctga acgattcgtg
661 gctgagtagg aggatgatac agaggacaac tggcttcttc aggccttacc aagactggaa
721 taggaaaccc cttcccacca tggatgactc caaactgaag aaggtggcca acatattcct
781 gtgtgctttg tcttcactat tcaccaggcc catcaaggac ataataggga agctaaggcc
841 tcttaacatc ctcaacattt tggcttcatg tgattggacc tttgcaggca tagtggaatc
901 cctaattctc ttggcagagc tctttggagt tttctggaca cccccagatg tgtctgcgat
961 gatcgccccc ttactgggtg actatgagct acaggggcct gaggacctcg cggtagagct
1021 agtgccagta gtgatggggg ggataggttt ggtgttggga ttcaccaaag aaaagattgg
1081 gaagatgttg tcatctgctg catccacatt gagggcttgt aaagaccttg gtgcatatgg
1141 actggagatc ctaaaactag tcatgaaatg gttcttccca aagaaagagg aagcaagcga
1201 gttagccatg gtgagatcta tcgaggacgc ggtgttggac ctcgaagcaa ttgagaacaa
1261 tcacttgacc accctgctta aggacaagga cagcctggcg acttacatga gaactcttga
1321 ccttgaggaa gagaaagcca ggaagctctc aaccaagtcc gcctcacctg atatcgtggg
1381 tacaatcaac gctctcctgg caaggattgc ggctgcccgc tccctagtac atcgggcaaa
1441 ggaagaactt tccagcagac cgagacccgt tgttgtgatg atatcaggaa agccagggat
1501 aggaaagact cacctagcca gagagctggc caagaagatc gcaaccaccc tcacagggga
1561 ccagagggtg ggcctcatcc cacgcaatgg cgttgaccac tgggatgcat acaagggaga
1621 gagggtcgtc ctttgggacg actacgggat gagcaacccc atccatgacg ctctcagatt
1681 gcaggagctt gctgacactt gccccctgac actaaattgt gataggattg aaaacaaagg
1741 taaagttttt gacagtgatg ccataattat caccaccaac ttggccaacc cagcaccact
1801 ggactatgtc aattttgagg cctgctcgag gcgcattgat ttcctcgtgt acgccgacgc
1861 ccctgatgtc gaaaaggcga agcgcgactt cccaggccaa cctgacatgt ggaaaaatgc
1921 tttcagccct gatttctctc acataaagct gatgctggcc ccacagggtg gttttgacaa
1981 gaacggcaac accccacatg ggaagggcgt catgaagacc ctcaccattg gttccctcat
2041 cgcccgtgct tcagggctcc tccacgagag gctggatgag tacgagctgc aaggcccagc
2101 cctcacaacc ttcaactttg accgaaacaa agtgctcgct ttcagacagc ttgctgctga
2161 aaataagtac ggactgatgg acacaatgag ggttggaggg caactcaagg gcgttagaac
2221 catgccagag ctcaagcaag cactcaagaa catttcaatt aagaggtgcc agatagtgta
2281 tggtggcagc acttatacac ttgaatctga tggcaagggt ggtgtgaagg tcgacagagt
2341 tcagagtacc accgtacaga ccaataatga gttagccggc gccctgcacc acctcaggtg
2401 cgccaggatc aggtactatg tcaagtgtgt ccaggaggcc ctgtactcca tcatccaaat
2461 tgcaggggcc gcatttgtca ccacgcgcat tgtcaagcgc atgaacatac aggacctttg
2521 gtccaagcca caactggaga acacagaaga agctgctagc aaagatgggt gcccaaaacc
2581 caaagatgat gaggagtttg ttgtttcatc tgatgacatc aagaccgagg gtaagaaagg
2641 aaagaacaag actggtcgcg gcaagaagca cacagccttc tcgagtaagg gtctcagtga
2701 cgaggagtac gatgagtaca aaagaatcag ggaggaaaga aacggcaagt actctataga
2761 ggagtatctc caagacagag acaagtatta tgaggaggtt gccattgcca gggcgactga
2821 ggaggacttc tgcgaagaag aagaggccaa gatccgtcaa agaatcttta gaccaacaag
2881 gaagcaacgc aaggaggaga gggcttctct cggtttagtc acaggctctg agatcagaaa
2941 aagaaaccca gatgacttca aacccaaggg aaaactgtgg gccgatgacg acagaagtgt
3001 cgattacaat gagaaactca gttttgaagc cccaccaagc atctggtcaa ggatagtcaa
3061 ctttggttcg ggttggggtt tctgggtttc tcctagtctg ttcataacat caactcatgt
3121 tataccccag ggcacacagg agttctttgg ggtgtccatc aaacaaatcc aggtacacaa
3181 atcaggcgaa ttttgccgct tgaggttccc aaagccaata aggactgatg tgacgggcat
3241 gatcttagag gaaggtgccc ccgaagggac cgtggccaca ctactcatca agaggccaac
3301 tggtgagctc atgcccttag cggccaggat gggcactcac gcaaccatga agatccaagg
3361 tcgcactgtt gggggccaaa tgggtatgct cctgacaggg tccaatgcca aaagtatgga
3421 cttgggcacc acacccggcg actgtggttg tccctacatc tacaagagag ggaacgacta
3481 cgtgggcatc ggagttcaca cagccgctgc ccatggagaa aacactgtca tatgtgccac
3541 ccagggaagt gaaggtgagg ccacacttga aggcggggat aataaaggtg cttactgtgg
3601 tgccccgatc ttaggtccag gaagtgcccc aaaactcagc accaaaacca agttctggag
3661 gtcatccaca gcaccactcc ctcctggtac ctatgagcca ccctacctcg gtggtaagga
3721 tcccagggtt aagggtggtc catcactaca acaagtcatg agggaccagt tgaaaccatt
3781 cactgaacca agaggtaaac aaccaaaacc aagtgtgttg gaagctgcca agagaaccat
3841 cattaatgtt cttgaacaaa caatagaccc acctcagaaa tggtcatttg cgcaagcttg
3901 cgcttctctt gacaaaacca cctccagtgg ccatccacac catatacgga agaatgaatg
3961 ctggaatgga gattccttta caggtaaatt ggcagaccag gcctcaaagg ccaacttgat
4021 gtttgaggag ggaaagaaca tgactccagt ttacacaggt gccctcaagg atgagttagt
4081 caaaactgac aagatatatg gcaagatcaa gaagaggcta ctttggggat cggacctggc
4141 aaccatgatc cggtgtgccc gggctttcgg aggcctaatg gatgaactca aggctcactg
4201 tgtcacactc cctgtcagag ttggtatgaa catgaatgaa gacggcccca tcatctttga
4261 aaaacattct aggtacaggt accactatga tgcagattac tctcgatggg actcaacaca
4321 acagagaccc atattggctg cagccctaga gatcatggtc aaattctccc cagagccaca
4381 cttagctcaa atagttgcag aagaccttct atcccccagt gtgatggatg taggtgattt
4441 taagatatca atcaacgagg gccttccctt tggggtgcct tgcacctcac aatggaactc
4501 catcgcccac tggctcctca ccctctgtgc actctctgaa gttacggacc tctcccctga
4561 catcatccag gctaattctc tcttctcttt ctatggtgat gatgaaattg tgagtacaga
4621 catacaattg gacccagaaa aactgacagc aaagctaaag gaatacgggc tgaagccaac
4681 tcgccctgat aagactgagg gacctctgat tatttctgag gacctaaatg gtttaacctt
4741 ccttcggagg accgtgaccc gcgacccagc tggttggttt ggtaaattgg aacagagttc
4801 gatactcagg cagatgtact ggaccagggg ccccaaccat gaggaccctt ctgaaacaat
4861 gataccacat tcccaaaggc ccatacaact gatgtccctg ctgggtgagg ctgcactgca
4921 tggcccagcg ttctacagca aaatcagcaa gctagtcatc acagagctaa aggaaggtgg
4981 catggatttt tacgtgccca gacaagagcc gatgttcagg tggatgaggt tctcagacct
5041 gagcacgtgg gagggcgatc gcaatctggc tcccagtttt gtgaatgaag atggcgtcga
5101 gtgacgccaa cccatctgat gggtccacag ccaacctcgt cccagaggtc aacaatgagg
5161 ttatggcttt ggagcctgtt gtcggtgctg ccattgcagc acctgtggca ggccaacaaa
5221 atataattga cccctggatt agaaataatt ttgtgcaagc ccctggtgga gagttcacag
5281 tgtcccctag aaatgctcca ggtgagatac tatggagcgc gcccttgagc cctgatttga
5341 acccctatct ttctcacctg tccagaatgt acaatggtta tgcaggtggc tttgaagtgc
5401 aggtaatcct cgcagggaat gcgttcactg ccgggaaaat catatttgca gcaattccac
5461 caaattttcc aactgaaggc ttaagcccta gccaggttac aatgttcccc cacataattg
5521 tagatgtcag gcaattggaa cctgtattaa tccccctacc tgatgttagg aataatttct
5581 atcattataa tcaagcacat gattctactc tcaaattgat agcaatgttg tatacaccac
5641 tcagagccaa taatgccggg gatgatgtct tcacagtctc ttgtcgagtc ctcacgagac
5701 catcccccga ttttgatttc atattcctgg tgccacccac agtcgagtca agaactaagc
5761 cattcactgt ccctatctta actgttgagg aaatgtccaa ttcaagattc cccattccct
5821 tagaaaagtt gtatacgggt cctagcagtg cttttgttgt tcaaccacaa aatggcagat
5881 gcacgactga tggcgtgctt ctaggcacta ctcagttgtc agctgtcaat atctgtaatt
5941 tcagggggga tgtcacccgt gttgggatca gccatgatta cacaatgaat ttggtgtccc
6001 aaaattggaa taactatgat ccaacagagg aaatccctgc tcccctggga acaccagact
6061 ttgtgggtaa gatccaaggt ctgctcactc aaaccacaag agcagacggc tcgactcgtg
6121 cccacaaagc cacagtgagc actgggagcg ttcacttcac cccaaagctg ggtagtgtcc
6181 aattcaccac cgacacaaac aatgactttc aaactggcca aaatacaaaa ttcaccccag
6241 ttggtgtcat ccaagatggt gatcaccacc agaatgaacc ccaacaatgg gtgctcccaa
6301 attactcagg cacctctggt cacaatgtgc atctggcccc tgccgttgct cccactttcc
6361 ccggtgagca gcttcttttc tttaggtcca ccatgcccgg gtgcagcggg taccctaaca
6421 tgaatttgga ttgcctgctc ccacaggagt gggtgtcgca cttctatcag gaagcagccc
6481 cagcacaatc agatgtggcc ctgctgagat ttgtgaatcc agatacaggt agggttttgt
6541 ttgagtgcaa actccataaa tcaggctaca tcacagtggc tcacactggt ccgtatgatt
6601 tggttattcc ccccaatggt tatttcagat ttgattcttg ggtcaaccag ttttacacac
6661 ttgcccccat gggaaatgga tcggggcgca agcgtgtgtt ataatggctg gatctttctt
6721 tgctggattg gcatctgatg ttcttggttc tggacttggt tctctaatca atgccggagc
6781 cggagcgatc aatcaaagag tggaatttga aaataatagg aaattacagc aagcttcctt
6841 ccaatttagc agcaatttac aacaagcttc ctttcaacat gacaaagaaa tgcttcaggc
6901 tcaaattgat gctactcaaa aattgcagca gggcttaatg cagatcaagc aggcggtgct
6961 tctggaaggt gggttttctg cggcagacgc cgctcgtggg gcaatcaacg cgcccatgac
7021 aaaaaccctg gactggagtg gaactaggta ctgggctccc gaggccagag tcacaacata
7081 caatgcaggc catttctccc cttcccagcc ttctaggacg ccgtctggga ggattagttc
7141 tgtgacttct gcatctgtgc gaaattcccc cagcttatct tctaaatctt ctactgctac
7201 aactgtgtat tctaatcaaa ctgtttcaac gagacttggt tcttcagctg gttctggaac
7261 cagtgtctcg agcctcccgt cggcttccag aaccaggagc tgggttgagg accaaaacag
7321 gagcgtgtca cccttcatga ggggagcact caacacatca tttgttactc ctccatctag
7381 cagatcctct aaccagagca cagtctcaac cgtacccaaa gaaattttgg actcctggac
7441 tggcgctttc aacacgcgca ggcagccgct cttcgcatac atccataagc gaggggagtc
7501 acgggtttga agtgaaaaga caatctgatc tttctttatt ttaatgtctt ttaaaaaaaa
7561 aaaaaaaaaa aaaaaa
//