Typing tool
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Typing tool
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Complete norovirus genomes
| FJ537134 | GII.4 | |
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| GII.P39 |
ORF1: 5..5104
ORF2: 5085..6704
ORF3: 6704..7510
LOCUS FJ537134 7580 bp RNA linear VRL 02-NOV-2009
DEFINITION Norovirus Hu/GII.4/CHDC5191/1974/US, complete genome.
ACCESSION FJ537134
VERSION FJ537134.1
KEYWORDS .
SOURCE Norovirus Hu/GII.4/CHDC5191/1974/US
ORGANISM Norovirus Hu/GII.4/CHDC5191/1974/US
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7580)
AUTHORS Bok,K., Abente,E.J., Realpe-Quintero,M., Mitra,T., Sosnovtsev,S.V.,
Kapikian,A.Z. and Green,K.Y.
TITLE Evolutionary dynamics of GII.4 noroviruses over a 34-year period
JOURNAL J. Virol. 83 (22), 11890-11901 (2009)
PUBMED 19759138
REFERENCE 2 (bases 1 to 7580)
AUTHORS Bok,K., Abente,E.J., Realpe-Quintero,M., Mitra,T., Sosnovtsev,S.V.,
Kapikian,A.Z. and Green,K.Y.
TITLE Direct Submission
JOURNAL Submitted (10-DEC-2008) Laboratory of Infectious Diseases,
Epidemiology Section, Norovirus Gastroenteritis Unit, National
Institute of Allergy and Infectious Diseases, National Institutes
of Health, 50 South Drive, BLD 50, Room 6316, Bethesda, MD 20892,
USA
FEATURES Location/Qualifiers
source 1..7580
/organism="Norovirus Hu/GII.4/CHDC5191/1974/US"
/mol_type="genomic RNA"
/strain="Hu/GII.4/CHDC5191/1974/US"
/host="Homo sapiens"
/db_xref="taxon:660660"
/country="USA"
/collection_date="1974"
/note="genotype: GII.4"
CDS 5..5104
/note="ORF-1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="ACT76138.1"
/translation="MKMASNDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARP
KQPPPREIPQRPPRPPTPELIKKVPPPPPNGEDEPVVSYNAKNGVSGLPELSTVRQPD
ENNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LAKVELTPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCALSSLFTRPIKDIIGK
LKPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEASELAMVRSIEDAVLDLEAIENNHLTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVVMISGKPGIGKTHLAREL
AKKIATTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPDVEK
AKRDFPGQPDMWKNAFSPDFSHIKLMLAPQGGFDKNGNTPHGKGVMKTLTIGSLIARA
SGLLHERLDEYELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGGQLKGVRTM
PELKQALKNISIKRCQIVYGGSTYTLESDGKGSVRVDRVQSATVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIVKRMNIQDLWSKPQLEDTEEATGKDGC
PKPKDDEEFVVSSDDIKVEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGTQEFFGVSIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRIKGGPSLQQVMRDQLKPFTEP
RGKQPKPSVLEAAKRTIINVLEQTIDPPQKWTFAQACASLDKTTSSGHPHHIRKNECW
NGDSFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAILAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFKISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIVQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPSETMIPHSQRPTQLMSLLGEAALHGPAFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
CDS 5085..6704
/note="structural protein; ORF-2"
/codon_start=1
/product="VP1"
/protein_id="ACT76139.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNIIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLSRMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQAHDSTLKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMSNSRFPIPLEKLYTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSAVNICNFRGDVTRVGISHDYTMNLVSQNWNNYDPTEEIPAPLGTPDFVGKIQGLL
TQTTRADGSTRAHKATVSTGSVHFTPKLGSVQFTTDTNNDFQTGQNTKFTPVGVIQDG
DHHQNEPQQWVLPNYSGTSGHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMNLDC
LLPQEWVLHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYITVAHTGPYDLVI
PPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6704..7510
/note="structural protein; ORF-3"
/codon_start=1
/product="VP2"
/protein_id="ACT76140.1"
/translation="MAGPFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATQKLQQGLMKVKQAVLLEGGFSTTDAARGAIN
APMTKALDWSGTRYWAPDARATTYNAGRFSTPQPLGALPGRINPRVPAPARSSPSSLS
NAPTATSVYSNQTVSTRLGSSAGSGAGVSSLPSTARTRSWVEDQNRNLSPFMRGALNT
SFVTPPSSRSSNQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgctgccgct gttgctaaca gcaacaacga
61 caccgcaaaa tcttcaagtg acggagtact ttctagtatg gctgtcacct ttaaacgagc
121 cctcggggcg cggcctaagc agccgccccc gagggagata ccacaaagac ccccacgacc
181 gcccactccg gagttgatca agaaggtccc tccccccccg cccaacgggg aggacgaacc
241 agtggtttct tacaacgcca agaatggcgt ttctggactg cctgagcttt ccactgtcag
301 gcaaccagat gagaacaaca cggcatttag tgtcccccca cttaaccaaa gggagaacag
361 ggatgccaag gagccactaa ctggaacaat cctggagatg tgggatgggg agatctacca
421 ctatggcttg tatgtggaac gaggcctggt gcttggcgtg cacaaaccgc cagcagctat
481 tagcctcgct aaggtcgaac ttacaccact ctctttgttt tggagacctg tctacactcc
541 ccagtacctc atctccccag acacccttag gagattgcat ggtgaatcgt tcccttacac
601 agcctttgac aacaactgtt atgccttctg ttgctgggtt ttggacctga acgactcatg
661 gctgagtagg aggatgatac agaggacaac tggcttcttc agaccttacc aggattggaa
721 caggaagccc cttcccacca tggatgattc caaattaaag aaagtggcca acatattcct
781 gtgtgcttta tcttcactat tcactagacc tatcaaggac ataataggaa agctaaaacc
841 ccttaacatt ctcaatattt tagcttcatg tgattggacc tttgcaggca tagtggaatc
901 tctaatcctc ttggcagaac tctttggagt tttctggaca cccccagatg tgtctgcgat
961 gattgccccc ttactgggtg actacgaact gcaggggcct gaggacctcg cagtagagct
1021 agtgccagta gtgatggggg gaataggttt ggtgctagga tttaccaaag aaaagattgg
1081 gaagatgttg tcatctgccg catccacact gagggcctgt aaagaccttg gtgcatatgg
1141 gctggagatc ttaaaactag tcatgaagtg gttcttcccg aagaaagagg aggcgagtga
1201 gttggccatg gtgagatcca tcgaggacgc ggtgttggac ctcgaagcaa ttgaaaacaa
1261 ccatttgacc accctgctta aggacaagga cagcctggca acttacatga gaactcttga
1321 ccttgaggaa gagaaagcca ggaaactctc aaccaagtct gcctcacctg acatcgtggg
1381 tacaatcaat gccctcctgg cgaggatcgc ggctgcccgt tccctggtac atcgagcaaa
1441 ggaagaactt tccagcaggc cgagacccgt tgtcgtgatg atatcaggaa aaccaggaat
1501 agggaagacc caccttgcca gagagctggc taagaagatc gcaaccaccc ttacgggaga
1561 ccagagggtg ggcctcatcc cacgcaatgg tgttgaccac tgggacgcgt acaagggaga
1621 gagggtcgtc ctttgggatg actacggtat gagtaatccc atccacgatg ccctcaggtt
1681 gcaggagctt gctgacactt gccccctaac actaaattgt gacaggattg agaacaaagg
1741 taaagttttt gacagtgatg ctataattat caccactaac ttggccaacc cagcaccact
1801 ggactatgtc aactttgagg cgtgctcgag gcgcattgat ttcctcgtgt acgccgaagc
1861 ccctgatgtt gagaaggcga agcgcgactt cccaggccaa cctgatatgt ggaagaatgc
1921 cttcagccct gacttctctc acataaagct gatgctggcc ccgcagggtg gctttgacaa
1981 gaacggcaat accccacatg ggaagggtgt catgaagacc ctcaccatcg gttctctcat
2041 cgcccgtgct tcaggactcc tccatgaaag gctggatgag tacgagttgc aaggcccagc
2101 cctcacaacc ttcaactttg accgaaacaa agtgctcgct ttcagacagc ttgctgctga
2161 aaacaagtac gggttgatgg atacgatgag agttggaggg caactcaagg gcgtcagaac
2221 catgccagag ctcaagcaag cactcaagaa catctcaatt aagaggtgcc agatagtgta
2281 tggtggcagc acctacacac ttgaatctga tggcaagggt agtgtgaggg ttgacagggt
2341 tcagagtgcc actgtgcaaa ccaacaacga actagccggc gccctgcatc atctcaggtg
2401 cgccaggatc aggtactatg tcaagtgtgt ccaggaagct ctgtactcca tcattcaaat
2461 tgcaggggct gcgtttgtca ccacgcgcat tgtcaagcgc atgaacatac aggatctatg
2521 gtccaagcca caactggagg acacggaaga agccactggc aaagacggat gcccaaaacc
2581 caaagatgat gaggagtttg ttgtctcatc cgacgacatc aaggttgagg gcaagaaagg
2641 gaagaacaag actggtcgcg gcaagaagca cacagccttc tcgagtaaag gtctcagtga
2701 tgaggagtac gacgagtaca aaagaatcag ggaggaaaga aacggcaagt attctataga
2761 ggagtacctc caagacagag acaagtatta tgaggaggtt gccatcgcca gggcgactga
2821 agaggatttc tgtgaagagg aagaggccaa gatccgacag agaatcttta gaccaacaag
2881 gaaacaacgc aaggaggaga gggcttctct cggtctagtc acaggctctg agatcaggaa
2941 aagaaaccca gatgacttca aacccaaggg aaagttgtgg gccgatgacg acagaagtgt
3001 cgattacaac gagaagctca gttttgaagc cccaccaagc atctggtcaa ggatagtcaa
3061 ctttggttcg ggttggggtt tctgggtttc ccccagtctg ttcataacat caactcatgt
3121 tataccccag ggcacacagg agttcttcgg agtgtccatc aagcaaatcc agatacacaa
3181 atcaggcgaa ttctgccgcc tgaggttccc aaaaccaatc aggaccgatg tgacaggcat
3241 gatcttagag gagggtgccc ccgaaggcac cgtggccaca ctactcatca agagaccaac
3301 tggtgaactc atgcctttag cagccaggat gggcactcat gcaaccatga agatccaagg
3361 tcgcactgtt ggaggccaaa tgggtatgct cctgacaggg tccaatgcca agagtatgga
3421 cctgggcacc acacctggcg actgtggttg tccctacatt tacaagagag ggaacgacta
3481 cgtggtcatc ggggttcaca cggctgctgc ccgaggaggg aacactgtca tatgtgccac
3541 ccagggaagt gaaggtgagg ccacacttga gggcggtgat aacaaaggca cctactgtgg
3601 cgctccgatc ctaggtccag gaagtgcccc aaagctcagc accaaaacca aattctggag
3661 atcatccaca gcaccactcc cacctggcac ctatgaacca gcctacctcg gtggtaagga
3721 ccccagaatc aagggtggcc cctcactaca acaagttatg agggaccagt tgaaaccatt
3781 cacggaacca agaggcaaac aaccaaagcc aagtgtgttg gaagctgcca agagaaccat
3841 tattaacgtc ctcgaacaaa caatagaccc acctcagaaa tggacgtttg cgcaagcttg
3901 cgcgtctctt gacaagacca cctccagtgg tcatccacac cacatacgga agaatgaatg
3961 ctggaatgga gattccttca caggcaagtt ggcagatcag gcctcaaagg ccaacttgat
4021 gtttgaggag gggaagaaca tgaccccagt ttacacaggt gccctcaagg atgagttggt
4081 caaaactgac aagatatatg gcaagattaa gaagagacta ctttggggat cggacctggc
4141 aaccatgatc cggtgtgccc gggcgttcgg gggcctaatg gatgagctca aggcccactg
4201 tgtcacactt cctgtcagag ttggtatgaa catgaatgag gatggcccca tcatctttga
4261 aaagcattcc aggtatagat atcactatga tgcagactat tctagatggg actcaacgca
4321 acaaagagct atattggctg cagccctaga gatcatggtc aaattctccc cagagccaca
4381 cttagcccag atagttgcag aagaccttct atcccccagc gtgatggacg tgggtgattt
4441 caagatttca atcaacgagg gcctcccctc tggggtgcct tgcacttcac aatggaattc
4501 tattgcccac tggctcctca ccctctgtgc tctctctgaa gtcacggatc tctcccctga
4561 catcgttcag gccaattctc tcttctcttt ctatggtgat gatgaaattg tgagcacaga
4621 tataaaattg gacccagaaa aactgacggc aaagctaaag gaatacggac tgaagccaac
4681 ccgccctgac aagactgaag gacctctaat catttctgag gatctaaatg gtttgacctt
4741 cctgcgaagg actgtaaccc gtgatccagc tggttggttt ggtaaattgg aacaaagctc
4801 aatactcagg cagatgtact ggaccagggg ccccaaccat gaggacccat ctgaaacaat
4861 gataccacat tcccaaaggc ccacgcagtt gatgtctttg ctgggtgagg ctgcactgca
4921 cggcccagca ttctacagca agatcagtaa actagtcatc acagagttaa aggaaggtgg
4981 catggatttt tacgtgccca gacaagagcc gatgttcagg tggatgagat tctcagacct
5041 gagcacgtgg gagggcgatc gcaatctggc tcccagtttt gtgaatgaag atggcgtcga
5101 gtgacgccaa cccatctgat gggtccgcag ccaacctcgt cccagaggtc aacaatgagg
5161 ttatggcttt ggagcctgtt gttggtgctg ccattgcagc acctgtggca ggccaacaaa
5221 atataattga cccctggatt agaaataatt ttgtacaagc ccctggtgga gagttcacag
5281 tgtcccctag aaacgctcca ggtgagatac tatggagcgc gcccttgggc cctgatttga
5341 acccctatct ttctcacctg tccagaatgt acaatggtta tgcaggtggt tttgaagtgc
5401 aagtgatcct cgcagggaac gcgttcaccg ccgggaaagt catatttgca gcagttccac
5461 caaattttcc aactgaaggt ctaagcccca gccaggttac tatgttcccc catataattg
5521 tagatgttag gcaattggaa cctgtattga tccccctacc tgatgttagg aataatttct
5581 atcattataa tcaagcacat gattctactc tcaaattgat agcaatgttg tacacaccac
5641 tcagagctaa taatgccggg gatgatgtct ttacagtctc ttgtcgagtc ctcacgagac
5701 catcccccga ttttgatttt atattcctgg tgccacccac agttgaatca agaactaaac
5761 catttactgt cccaatctta actgttgagg aaatgtccaa ttcaagattc cccattcctt
5821 tggaaaagct gtacacgggt cctagcagtg cttttgttgt ccaaccacaa aatggcagat
5881 gcacgactga tggcgtgctc ttaggcacta ctcagctgtc agctgtcaat atctgcaact
5941 tcagggggga tgtcacccgt gttgggatca gccatgatta tacaatgaat ttggtgtccc
6001 aaaattggaa taattatgat ccaacagaag aaattccagc tcccctggga acaccagact
6061 ttgtaggaaa gatccaaggt ttgctcaccc aaaccacaag agcggacggc tcgacccgcg
6121 cccacaaagc tacagtgagc actgggagtg tccacttcac tccaaagctg ggtagtgttc
6181 aattcaccac cgatacgaac aatgatttcc aaactggcca aaacacaaaa tttaccccag
6241 ttggtgtcat ccaagacggt gatcaccatc agaatgaacc ccaacaatgg gtactcccaa
6301 attactcagg cacatctggt cacaatgtgc atctggcccc tgccgttgcc cccactttcc
6361 cgggtgagca gcttcttttc tttaggtcca ctatgcccgg gtgtagcggg taccccaaca
6421 tgaatttgga ttgcctactc ccccaggagt gggtgctgca cttttaccag gaagcagccc
6481 cagcacaatc cgatgtggcc ctgctgagat ttgtgaatcc agacacaggt agggttctgt
6541 ttgagtgcaa actccataag tcaggctata tcacagtggc tcatactggc ccgtatgatt
6601 tggttatccc ccccaatggt tacttcagat ttgattcttg ggtcaaccag ttctacacac
6661 tcgcccccat gggaaatgga acggggcgca ggcgtgcttt ataatggctg gacctttctt
6721 tgctggattg gcatctgatg tcctcggttc tggacttggt tctctaatca atgctggagc
6781 tggagccatc aatcaaaaag ttgaatttga aaataataga aaattgcaac aagcttcttt
6841 tcaattcagt agtaatctgc aacaggcttc cttccaacat gataaggaga tgctccaagc
6901 acaaattgag gctactcaaa aattgcaaca aggtttgatg aaggttaaac aggcagtgct
6961 cctagagggt gggttttcca caacagatgc ggcccgtggg gcaatcaacg cccccatgac
7021 aaaggctctg gactggagcg gaacaaggta ctgggcccct gatgccaggg ccacaacata
7081 caatgcaggc cgcttctcca cccctcagcc tttgggggca ttacctggaa gaatcaatcc
7141 tagggttcct gcacctgctc ggagctcccc cagttcactt tccaatgctc ctactgctac
7201 ttctgtgtat tccaatcaaa ctgtttctac gagactaggt tcttcagctg gttctggtgc
7261 cggtgtctcg agtctcccgt caactgcaag gactaggagc tgggttgagg accaaaacag
7321 aaatttgtcg cctttcatga ggggggctct caacacatca tttgtcaccc ctccatctag
7381 tagatcctcc aaccaaggca cagtctcaac cgtgcctaaa gagattttgg actcctggac
7441 tggcgctttt aacacgcgca ggcagcctct cttcgcacac attcgtaagc gaggggagtc
7501 acgggtgtaa tgtgaaaaga caaaattgat tatctttctt ttctttagtg tcttttaaaa
7561 aaaaaaaaaa aaaaaaaaaa
//