Typing tool
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Typing tool
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Complete norovirus genomes
| AJ583672 | GII.4 Farmington Hills | |
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| GII.P4 Farmington Hills |
ORF1: 1..2519
ORF2: 2500..4119
ORF3: 4119..4925
LOCUS AJ583672 4970 bp RNA linear VRL 26-JUL-2016
DEFINITION Norwalk virus gene for polyprotein (partial), ORF2 and ORF3,
genomic RNA.
ACCESSION AJ583672
VERSION AJ583672.2
KEYWORDS 3A protein; 3C-proteinase; minor structural protein; ORF1; ORF2;
ORF3; polyprotein; RNA dependent RNA polymerase; VP60 capsid
protein; VPg.
SOURCE Norwalk virus
ORGANISM Norwalk virus
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus.
REFERENCE 1
AUTHORS Ng,K.K., Pendas-Franco,N., Rojo,J., Boga,J.A., Machin,A.,
Alonso,J.M. and Parra,F.
TITLE Crystal structure of norwalk virus polymerase reveals the carboxyl
terminus in the active site cleft
JOURNAL J. Biol. Chem. 279 (16), 16638-16645 (2004)
PUBMED 14764591
REFERENCE 2 (bases 1 to 4970)
AUTHORS Boga,J.A.
TITLE Direct Submission
JOURNAL Submitted (25-SEP-2003) Boga J.A., Microbiologia I, Hospital
Central de Asturias, Celestino Villamil s/n, 33006, SPAIN
REMARK revised by author [22-JAN-2004]
FEATURES Location/Qualifiers
source 1..4970
/organism="Norwalk virus"
/mol_type="genomic RNA"
/isolate="Ast6139/01/Sp"
/db_xref="taxon:11983"
CDS <1..2519
/experiment="experimental evidence, no additional details
recorded"
/codon_start=3
/product="polyprotein"
/protein_id="CAE47528.2"
/db_xref="GOA:Q70ET3"
/db_xref="InterPro:IPR001205"
/db_xref="InterPro:IPR001665"
/db_xref="InterPro:IPR007094"
/db_xref="InterPro:IPR009003"
/db_xref="PDB:1SH0"
/db_xref="PDB:1SH2"
/db_xref="PDB:1SH3"
/db_xref="PDB:3BSN"
/db_xref="PDB:3BSO"
/db_xref="PDB:3H5X"
/db_xref="PDB:3H5Y"
/db_xref="UniProtKB/TrEMBL:Q70ET3"
/translation="DEEFVISSDDINTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEY
KRIREERNGKYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRK
EERASLGLVTGSEIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFG
SGWGFWVSPSLFITSTHVIPQGAKEFFGVPIKQTQIHKSGEFCRLRFPKPIRTDVTGM
ILEEGAPEGTVVTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKS
MDLGTTPGDCGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKG
TYCGAPILGPGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMR
DQLKPFTEPRGKPPKPSVLEAAKKTIINVLEQTIDPPDKWSFAQACASLDKTTSSGHP
HHMRKNDCWNGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIK
KRLLWGSDLATMIRCARAFGGLMDELKTHCVTLPIRVGMNMNEDGPIIFERHSRYRYH
YDADYSRWDSTQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINE
GLPSGVPCTSQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLD
PEKLTAKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSIL
RQMYWTRGPNHEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGG
MDFYVPRQEPMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..44
/product="putative 3A protein"
mat_peptide 45..443
/product="VPg"
/experiment="experimental evidence, no additional details
recorded"
mat_peptide 444..986
/product="3C-proteinase"
/experiment="experimental evidence, no additional details
recorded"
mat_peptide 987..2516
/product="RNA dependent RNA polymerase"
/function="replication"
/experiment="experimental evidence, no additional details
recorded"
CDS 2500..4119
/note="ORF2"
/codon_start=1
/product="VP60 capsid protein"
/protein_id="CAE47529.1"
/db_xref="InterPro:IPR004005"
/db_xref="InterPro:IPR013643"
/db_xref="UniProtKB/TrEMBL:Q70ET2"
/translation="MKMASNDANPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKTIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQPEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMTNSRFPIPLEKLFTGPSNAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHIAGTHDYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
SQTTRGDGSTRGHKATVSTGSVHFTPKLGSVQYTTDTNNDLEAGQSTKFTPVGVVQDG
NNHQNEPQQWVLPNYSGRTGHNVHLVPAVAPTFPGEQLLFFRSTMPGCSGYPNMNLDC
LLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGPHDLVI
PPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 4119..4925
/note="ORF3"
/codon_start=1
/product="minor structural protein"
/protein_id="CAE47530.1"
/db_xref="InterPro:IPR004278"
/db_xref="UniProtKB/TrEMBL:Q70ET1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATQKLQQGMMKVKQAMLLEGGFSEADAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRTNPRATVPARGSPSIPC
STSTVTSVYSNQTVSTRLGSTAGSGTSVSSLPSNARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHVRKRGESRV"
3'UTR 4926..4970
ORIGIN
1 atgatgagga gttcgtcatt tcatccgacg acatcaacac tgagggtaag aaagggaaga
61 acaaaactgg ccgcggcaag aagcacacag ccttctcaag caaaggtctc agtgatgaag
121 agtacgatga gtacaagagg attagagaag aaagaaatgg caagtattcc atagaagagt
181 accttcagga cagggacaaa tactatgagg aggtggccat tgccagggcg accgaggaag
241 acttctgcga agaggaggag gccaagatcc ggcaaaggat cttcaggcca acaaggaaac
301 aacgcaagga ggaaagagcc tctctcggtt tagtcacagg ttctgaaatt aggaagagaa
361 acccagatga tttcaagccc aaggggaagc tgtgggctga cgatgacaga agtgtggact
421 acaatgagaa actcagtttt gaggccccac caagcatctg gtcgaggata gtcaactttg
481 gttcaggttg gggcttctgg gtctccccca gtctgttcat aacatcaacc catgtcatac
541 cccagggcgc aaaggagttc tttggagtcc ccatcaaaca aactcagata cacaagtcag
601 gcgaattttg tcgcttgagg ttcccaaagc caatcaggac tgatgtgacg ggcatgatct
661 tagaagaagg tgcgcccgaa ggcaccgtgg tcacactact catcaaaagg tctactggag
721 aacttatgcc cctagcagct agaatgggga cccatgcaac catgaaaatt caagggcgca
781 ctgttggagg tcagatgggc atgcttctga caggatccaa cgccaaaagc atggatctgg
841 gcaccacacc aggcgattgc ggctgcccct acatctacaa gagaggaaat gactatgtgg
901 tcattggagt ccacacggct gctgctcgtg ggggaaacac tgtcatatgt gccacccagg
961 ggagtgaggg ggaggctaca cttgaaggtg gtgacagtaa gggaacatac tgtggtgcac
1021 caatcctagg cccagggagt gccccaaaac ttagcaccaa gaccaaattc tggagatcgt
1081 ccacagcacc actcccacct ggcacctatg aaccagccta tcttggtggt aaggacccca
1141 gagtcaaggg tggcccttca ttgcagcaag tcatgaggga tcagttgaaa ccatttacag
1201 agcccagggg caagccacca aagccaagtg tgttggaagc tgccaagaaa accatcatca
1261 atgtccttga acaaacaatt gatccacctg ataagtggtc attcgcacaa gcttgcgcgt
1321 ccctcgacaa gaccacttcc agtggccatc cgcaccacat gcggaagaac gactgctgga
1381 acggggaatc cttcacaggc aagctggcag accaggcttc caaggccaac ctgatgttcg
1441 aagaagggaa gaacatgacc ccagtctaca caggtgcgct taaggatgaa ttagtcaaaa
1501 ctgacaaaat ttatggtaag atcaagaaga ggcttctctg gggctcggat ttagcgacca
1561 tgatccggtg tgctcgagcg ttcggaggcc taatggatga actcaaaaca cactgtgtta
1621 cactccctat cagagttggt atgaatatga atgaggatgg ccccatcatc ttcgagaggc
1681 attccaggta cagatatcac tatgatgctg attactctcg gtgggattca acacaacaga
1741 gagccgtgtt ggcagcagcc ttagaaatca tggttaaatt ctcctcagaa ccacatttgg
1801 ctcaagtagt cgcagaagac cttctttctc ctagcgtggt ggatgtgggt gacttcacaa
1861 tatcaatcaa tgagggtctt ccctctgggg tgccctgcac ctcccaatgg aactccatcg
1921 cccactggct tctcactctc tgtgcgctct ctgaagttac aaacttgtcc cccgacatca
1981 tacaggccaa ttctctcttc tccttttatg gtgatgatga aattgttagt acagacataa
2041 agttggaccc agaaaaattg acagcaaagc tcaaggaata cggattgaaa ccaacccgcc
2101 ctgacaaaac tgaaggaccc cttgttattt ctgaggactt aaatggtctg actttcctgc
2161 ggagaactgt gacccgcgac ccagctggtt ggtttggaaa actggagcag agttcaatac
2221 tcaggcaaat gtactggact aggggcccca accatgaaga cccatctgaa acaatgattc
2281 cacattccca aagacccata caactgatgt ccttactggg agaggccgca ctccacggcc
2341 cagcattcta cagcaaaatc agcaagttag tcattgcaga gctaaaagaa ggtggcatgg
2401 atttttacgt acccagacaa gagccaatgt tcagatggat gagattctca gatctgagca
2461 cgtgggaggg cgatcgcaat ctggctccca gttttgtgaa tgaagatggc gtcgaatgac
2521 gccaacccat ctgatgggtc cacagccaac ctcgtcccag aggtcaacaa tgaggttatg
2581 gctttggagc ccgttgttgg tgccgctatt gcggcacctg tagcgggcca acaaaatgta
2641 attgacccct ggattagaaa taattttgta caagcccctg gtggagagtt tacagtatcc
2701 cccagaaacg ctccaggtga aatactatgg agcgcgccct tgggccctga tctgaatccc
2761 tacctttctc acttggccag aatgtacaat ggttatgcag gtggttttga agtgcaggta
2821 attctcgcgg ggaacgcgtt caccgccggg aaaaccatat ttgcagcagt cccaccaaac
2881 ttcccaactg aaggcttgag ccccagccag gtcactatgt tcccccatat aatagtagat
2941 gttaggcaac cggaacctgt gttgatcccc ttacctgatg ttaggaataa tttctatcac
3001 tacaatcaat caaatgaccc tactataaaa ttgatagcaa tgctgtacac accacttagg
3061 gctaataatg ctggggatga tgtcttcaca gtctcttgtc gagtcctcac cagaccatcc
3121 cccgattttg atttcatatt tttggtgcca cccacagttg agtcaagaac taaaccattc
3181 accgtcccaa ttttaactgt tgaggaaatg accaattcaa gattccccat tcctttggaa
3241 aagttattca cgggtcccag caatgccttt gttgttcaac cacaaaatgg caggtgcacg
3301 accgatggcg tgctcttagg cactacccaa ctgtctcctg tcaacatctg caccttcaga
3361 ggggatgtca cccacattgc aggtacccat gattacacaa tgaatttggc ttctcaaaat
3421 tggaacaatt atgacccaac agaagaaatc ccagcccctc tgggaactcc agatttcgtg
3481 ggaaagatcc aaggcgtgct ctcccaaacc acaagggggg atggctcgac ccgcggccac
3541 aaagctacag tgagcactgg gagtgtccac ttcactccaa agctgggcag tgttcaatac
3601 accactgaca caaacaatga tcttgaagct ggccaaagca cgaaatttac cccagtcggt
3661 gtcgtccagg atggtaataa ccaccaaaat gaaccccaac aatgggtgct cccaaattac
3721 tcaggtagaa ctggtcataa tgtgcaccta gtccctgccg tagcccccac ttttccgggt
3781 gagcaacttc ttttcttcag gtccactatg cccggatgca gcgggtatcc caacatgaat
3841 ttggattgtc tactccccca ggaatgggtg cagcacttct accaagaggc agctccagca
3901 caatctgatg tggctctgct gagatttgtg aatccagaca caggcagggt tctgtttgag
3961 tgcaagcttc ataaatcagg ctacgtcaca gtagctcaca ctggcccgca tgatttggtt
4021 attcctccca atggctactt tagatttgat tcctgggtca accaattcta cacacttgcc
4081 cccatgggaa acggaacggg gcgtagacgt gcattataat ggctggagct ttctttgctg
4141 gattggcatc tgatgtcctt ggctctggac ttggttccct aatcaatgct ggggctgggg
4201 ccatcaacca aaaagttgaa tttgaaaata acagaaaatt gcaacaagct tccttccaat
4261 ttagcagcaa tctacaacag gcttccttcc aacatgataa agagatgctc caagcacaga
4321 ttgaggccac tcaaaaattg caacagggta tgatgaaagt taaacaggca atgctcctag
4381 agggtggatt ctctgaagca gatgcagccc gtggggcaat caacgccccc atgacaaagg
4441 ctctggactg gagcggaaca agatactggg ctcctgatgc taggactaca acatacaatg
4501 caggccgctt ttccacccct caaccttcgg gggcactgcc aggaagaact aatcccaggg
4561 ctactgtccc cgctcggggc tcccccagca taccttgtag tacttctact gttacctctg
4621 tgtattcaaa tcaaactgtt tcaacgagac ttggttctac agctggttct ggtaccagtg
4681 tctcgagtct cccgtcaaat gcaaggacta ggagctgggt tgaggatcaa aacagaaatt
4741 tgtcaccttt catgaggggg gctcacaaca tatcatttgt caccccacca tctagtagat
4801 cctctagcca aggcacagtc tcaaccgtgc ctaaagaaat tttggactcc tggactggcg
4861 ctttcaacac gcgcaggcag cctctcttcg ctcacgttcg taagcgaggg gagtcacggg
4921 tgtaatgtga aaagacaaaa ttgattatct ttcctttctt tagtgtcttt
//