Typing tool
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Typing tool
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Complete norovirus genomes
| AF414425 | GII.4 US95 | |
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| GII.P4 US95 |
ORF1: 1..591
ORF2: 572..2191
ORF3: 2191..2997
LOCUS AF414425 3043 bp ss-RNA linear VRL 26-JUL-2016
DEFINITION Norwalk-like virus NLV/Burwash Landing/331/1995/US RNA polymerase
(orf1) gene, partial cds; and capsid protein (orf2) and minor
structural protein (orf3) genes, complete cds.
ACCESSION AF414425
VERSION AF414425.1
KEYWORDS .
SOURCE Norwalk-like virus NLV/Burwash Landing/331/1995/US
ORGANISM Norwalk-like virus NLV/Burwash Landing/331/1995/US
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 3043)
AUTHORS Ando,T., Monroe,S.S., Noel,J.S. and Glass,R.I.
TITLE A one-tube method of reverse transcription-PCR to efficiently
amplify a 3-kilobase region from the RNA polymerase gene to the
poly(A) tail of small round-structured viruses (Norwalk-like
viruses)
JOURNAL J. Clin. Microbiol. 35 (3), 570-577 (1997)
PUBMED 9041391
REFERENCE 2 (bases 871 to 1147)
AUTHORS Noel,J.S., Ando,T., Leite,J.P., Green,K.Y., Dingle,K.E.,
Estes,M.K., Seto,Y., Monroe,S.S. and Glass,R.I.
TITLE Correlation of patient immune responses with genetically
characterized small round-structured viruses involved in outbreaks
of nonbacterial acute gastroenteritis in the United States, 1990 to
1995
JOURNAL J. Med. Virol. 53 (4), 372-383 (1997)
PUBMED 9407386
REFERENCE 3 (bases 1 to 3043)
AUTHORS Noel,J.S., Fankhauser,R.L., Ando,T., Monroe,S.S. and Glass,R.I.
TITLE Identification of a distinct common strain of 'Norwalk-like
viruses' having a global distribution
JOURNAL J. Infect. Dis. 179 (6), 1334-1344 (1999)
PUBMED 10228052
REFERENCE 4 (bases 1 to 3043)
AUTHORS Ando,T., Seto,Y., Noel,J.S., Monroe,S.S., Glass,R.I. and
Fankhauser,R.L.
TITLE Direct Submission
JOURNAL Submitted (27-AUG-2001) Viral Gastroenteritis Section/Division of
Viral and Rickettsial Diseases/National Center for Infectious
Diseases, Centers for Disease Control and Prevention, 1600 Clifton
Road, Atlanta, GA 30333, USA
FEATURES Location/Qualifiers
source 1..3043
/organism="Norwalk-like virus NLV/Burwash
Landing/331/1995/US"
/mol_type="genomic RNA"
/strain="Hu/NLV/Burwash Landing/331/1995/US"
/db_xref="taxon:171857"
/clone="pYS24C"
/note="NLV/Burwash Landing; NLV/331; NLV/S24;
group: GII/4"
gene <1..591
/gene="orf1"
CDS <1..591
/gene="orf1"
/note="nonstructural protein"
/codon_start=1
/product="RNA polymerase"
/protein_id="AAL13027.1"
/translation="LLTLCALSEVTNLSPDIIQANSLFSFYGDDDIVSTDIKSDPEKL
TAKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMY
WTRGPNHEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFY
VPRQEPMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
gene 572..2191
/gene="orf2"
CDS 572..2191
/gene="orf2"
/note="major structural protein"
/codon_start=1
/product="capsid protein"
/protein_id="AAL13028.1"
/translation="MKMASNDANPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTASPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTASCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMSNSRFPIPLEKLYTGPSSAFVVQPQSGRCTTDGVLLGTT
QLSAVNICTFRGDVTHIAGSHDYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTREDGSTRAHKATVSTGSVHFTPKLGSVQYTTDTNNDFQTGQNTKFTPVGVIQDG
NNHQNEPQQWVLPNYSGRTGHNVHLAPAVAPTFPGEQLLFFKSTMPGCSGYPNMNLDC
LLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGPHDLVI
PPNGYFRFDSWVNQFYTLAPMGNGAGRRRAL"
gene 2191..2997
/gene="orf3"
CDS 2191..2997
/gene="orf3"
/codon_start=1
/product="minor structural protein"
/protein_id="AAL13029.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQSSLQHDKEMLQAQIEATKNLQQGMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRTNLRATVPARGSSSTLS
STPTATSVYSNQTVSTRLGSSAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGALNT
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
3'UTR 2998..3043
ORIGIN
1 cttctcactc tctgtgcgct ctctgaagtt acaaacttgt cccctgacat catacaggct
61 aattccctct tctcctttta tggtgatgat gatattgtta gtacagatat aaagtcggac
121 ccagagaaat tgacagcaaa actcaaggaa tacgggttga aaccaacccg ccctgacaaa
181 actgaagggc cccttgttat ttctgaagac ttaaatggtc tgaccttcct gcggagaact
241 gtgacccgcg acccagctgg ttggtttgga aaattggagc agagttcaat actcagacaa
301 atgtactgga ctaggggccc caaccatgaa gacccatctg aaacaatgat tccacattcc
361 caaagaccca tacaattgat gtccctactg ggagaggccg ctctccacgg cccagcattc
421 tacagcaaga ttagcaagtt agttattgca gagctaaaag aaggtggcat ggatttttac
481 gtgcccagac aagagccaat gttcagatgg atgagattct cagatctgag cacgtgggag
541 ggcgatcgca atctggctcc cagttttgtg aatgaagatg gcgtcgaatg acgccaaccc
601 atctgatggg tccacagcca acctcgtccc agaggtcaac aatgaggtta tggctttgga
661 gcccgttgtt ggtgccgcta ttgcggcacc tgtagcgggc caacaaaatg taattgaccc
721 ctggattaga aataattttg tacaagcccc tggtggagag tttacagcat cccctagaaa
781 cgctccgggt gagatactat ggagcgcgcc cttgggccct gatttgaacc cctacctttc
841 tcatttggcc agaatgtaca atggttatgc aggtggtttt gaagtgcagg taatcctcgc
901 ggggaacgcg ttcaccgccg ggaaaatcat atttgcagca gtcccaccaa attttccaac
961 tgaaggcttg agccccagcc aggttactat gttcccccat ataatagtag atgttaggca
1021 attggaacct gtgttgattc ccttacctga tgttaggaac aatttctacc attacaatca
1081 atcaaatgat tctaccatta aattgatagc aatgctgtat acaccactta gggctaataa
1141 tgctggggat gatgtcttca cagcctcttg tcgagtcctc acgaggccat cccccgattt
1201 tgatttcata ttcttggtgc cacccacagt tgaatcaaga actaaaccat tcaccgtccc
1261 aatcttaact gttgaggaaa tgtccaattc gagattcccc attcctttgg aaaagttgta
1321 cacgggcccc agcagtgctt ttgttgtcca accacaaagt ggcaggtgca cgactgatgg
1381 cgtgctctta ggcactaccc agctgtctgc tgtcaacatc tgcaccttca gaggggatgt
1441 cacccacatt gcaggcagtc atgattatac aatgaatttg gcttctcaaa attggaacaa
1501 ttatgaccca acagaagaaa tcccagcccc tctgggaact ccagatttcg tgggaaagat
1561 ccaaggcatg ctcacccaaa ccacaagaga ggatggctcg acccgcgccc acaaagctac
1621 agtgagcact gggagtgtcc actttactcc aaagctgggc agtgttcaat acaccactga
1681 cacaaacaat gatttccaaa ctggccaaaa cacgaaattc accccagtcg gcgtcatcca
1741 ggacggtaat aaccatcaaa atgaacccca acaatgggta ctcccaaatt actcaggcag
1801 aactggtcat aatgtgcacc tagctcctgc cgttgccccc acctttccgg gtgagcaact
1861 tcttttcttt aagtctacta tgcccggatg tagcgggtat cccaacatga atctggattg
1921 cctactcccc caggaatggg tgcagcactt ctaccaagaa gcagctccag cacaatctga
1981 tgtagctctg ctgagatttg tgaatccaga tacaggtagg gttttgtttg agtgcaagct
2041 ccataaatca ggctatgtca cagtggctca cactggtccg catgatttgg ttatcccccc
2101 caatggttac tttagatttg actcctgggt caaccagttc tacacacttg cccccatggg
2161 aaatggagcg gggcgtagac gtgcattata atggctggag ctttctttgc tggattggca
2221 tctgatgtcc ttggctctgg acttggttcc ctaatcaatg ctggggctgg ggccatcaac
2281 caaaaagttg aatttgaaaa caacagaaaa ttgcaacaag cttccttcca atttagtagc
2341 aatctacaac agtcttccct ccaacatgat aaagagatgc tccaagcaca aattgaggcc
2401 actaaaaatt tgcaacaggg tatgatgaag gttaaacagg cgatgctcct agagggtgga
2461 ttctctgaaa cagatgcagc ccgtggggca atcaacgccc ccatgacaaa ggctctggac
2521 tggagcggaa caaggtactg ggctcctgat gccaggacca caacatacaa tgcaggccgc
2581 ttttccaccc ctcaaccttc gggggcattg ccaggaagaa ctaatcttag ggctactgtc
2641 cccgctcggg gctcctctag tacactttct agtactccca ctgctacttc tgtgtattca
2701 aatcaaactg tttcaacgag acttggttct tcagctggtt ctggtaccag tgtctcgagt
2761 ctcccgtcaa ctgcaaggac taggagctgg gttgaggatc aaaacagaaa tttgtcacct
2821 tttatgaggg gggctctcaa cacgtcattt gtcaccccac catctagtag atcctctagc
2881 caaggcacag tctcgaccgt gcctaaagaa attttggact cctggactgg cgcttttaac
2941 acgcgcaggc agcctctctt cgctcacatt cgtaagcggg gggagtcacg ggtgtaatgt
3001 gaaaagacaa aattgattat cttccctttc tttagtgtct tac
//