Typing tool
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Typing tool
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Complete norovirus genomes
| AF414424 | GII.4 US95 | |
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| GII.P4 US95 |
ORF1: 1..591
ORF2: 572..2191
ORF3: 2191..2979
LOCUS AF414424 3025 bp ss-RNA linear VRL 26-JUL-2016
DEFINITION Norwalk-like virus NLV/Miami Beach/326/1995/US RNA polymerase
(orf1) gene, partial cds; and capsid protein (orf2) and minor
structural protein (orf3) genes, complete cds.
ACCESSION AF414424
VERSION AF414424.1
KEYWORDS .
SOURCE Norwalk-like virus NLV/Miami Beach/326/1995/US
ORGANISM Norwalk-like virus NLV/Miami Beach/326/1995/US
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 3025)
AUTHORS Ando,T., Monroe,S.S., Noel,J.S. and Glass,R.I.
TITLE A one-tube method of reverse transcription-PCR to efficiently
amplify a 3-kilobase region from the RNA polymerase gene to the
poly(A) tail of small round-structured viruses (Norwalk-like
viruses)
JOURNAL J. Clin. Microbiol. 35 (3), 570-577 (1997)
PUBMED 9041391
REFERENCE 2 (bases 871 to 1147)
AUTHORS Noel,J.S., Ando,T., Leite,J.P., Green,K.Y., Dingle,K.E.,
Estes,M.K., Seto,Y., Monroe,S.S. and Glass,R.I.
TITLE Correlation of patient immune responses with genetically
characterized small round-structured viruses involved in outbreaks
of nonbacterial acute gastroenteritis in the United States, 1990 to
1995
JOURNAL J. Med. Virol. 53 (4), 372-383 (1997)
PUBMED 9407386
REFERENCE 3 (bases 871 to 1147)
AUTHORS Noel,J.S., Fankhauser,R.L., Ando,T., Monroe,S.S. and Glass,R.I.
TITLE Identification of a distinct common strain of 'Norwalk-like
viruses' having a global distribution
JOURNAL J. Infect. Dis. 179 (6), 1334-1344 (1999)
PUBMED 10228052
REFERENCE 4 (bases 1 to 3025)
AUTHORS Ando,T., Noel,J.S. and Fankhauser,R.L.
TITLE Genetic classification of 'Norwalk-like viruses.
JOURNAL J. Infect. Dis. 181 (Suppl 2), S336-S348 (2000)
PUBMED 10804147
REFERENCE 5 (bases 1 to 3025)
AUTHORS Ando,T., Seto,Y., Noel,J.S., Monroe,S.S., Glass,R.I. and
Fankhauser,R.L.
TITLE Direct Submission
JOURNAL Submitted (27-AUG-2001) Viral Gastroenteritis Section/Division of
Viral and Rickettsial Diseases/National Center for Infectious
Diseases, Centers for Disease Control and Prevention, 1600 Clifton
Road, Atlanta, GA 30333, USA
FEATURES Location/Qualifiers
source 1..3025
/organism="Norwalk-like virus NLV/Miami Beach/326/1995/US"
/mol_type="genomic RNA"
/strain="Hu/NLV/Miami Beach/326/1995/US"
/db_xref="taxon:171856"
/clone="pYS23C"
/note="NLV/326; NLV/S23;
group: GII/4"
gene <1..591
/gene="orf1"
CDS <1..591
/gene="orf1"
/note="nonstructural protein"
/codon_start=1
/product="RNA polymerase"
/protein_id="AAL13024.1"
/translation="LLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKL
TAKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMY
WTRGPNHEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFY
VPRQEPMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
gene 572..2191
/gene="orf2"
CDS 572..2191
/gene="orf2"
/note="major structural protein"
/codon_start=1
/product="capsid protein"
/protein_id="AAL13025.1"
/translation="MKMASNDANPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVGQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMSNSRFPIPLEKLYTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSAVNICTFRGDVTHIAGSHDYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTREDGSTRAHKATVSTGSVHFTPKLGSVQYTTDTNNDFQTGQNTKFTPVGVIQDG
NNHQNEPQQWVLPNYSGRTGHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMNLDC
LLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGPHDLVT
PPNGYFRFDSWVNQFYTLAPMGNGAGRRRAL"
gene 2191..2979
/gene="orf3"
CDS 2191..2979
/gene="orf3"
/codon_start=1
/product="minor structural protein"
/protein_id="AAL13026.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQGMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRTNLRATVPARGSSSTLS
STPTATSVYSNQTVSTRLGSSAGSGTSVSSLPSTARTRSWVEDQNVRGALNTSFVTPP
SSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
3'UTR 2980..3025
ORIGIN
1 cttctcactc tctgtgcgct ctctgaagtt acaaacttgt cccctgacat catacaggct
61 aattccctct tctcctttta tggtgatgat gaaattgtta gcacagatat aaagttggac
121 ccagagaaat tgacagcaaa actcaaggaa tacgggttga aaccaacccg ccctgacaaa
181 actgaagggc cccttgttat ttctgaagac ttaaatggtc tgaccttcct gcggagaact
241 gtgacccgcg acccagctgg ttggtttgga aaattggagc agagttcaat actcagacaa
301 atgtattgga ctaggggccc caaccatgaa gacccatctg aaacaatgat tccacattcc
361 caaagaccca tacaattgat gtccctactg ggagaggccg cactccacgg cccagcattc
421 tacagcaaaa ttagtaagtt agtcattgca gagctaaaag aaggtggcat ggatttttac
481 gtgcccagac aagagccaat gttcagatgg atgagattct cagatctgag cacgtgggag
541 ggcgatcgca atctggctcc cagttttgtg aatgaagatg gcgtcgaatg acgccaaccc
601 atctgatggg tccacagcca acctcgtccc agaggtcaac aatgaggtta tggctttgga
661 gcccgttgtt ggtgccgcta ttgcggcacc tgtagcgggc caacaaaatg taattgaccc
721 ctggattaga aataattttg tacaagcccc tggtggagag tttacagtat cccctagaaa
781 cgctccgggc gagatactat ggagcgcgcc cttgggccct gatttgaacc cctacctttc
841 tcatttggcc agaatgtaca atggttatgc aggtggtttt gaagtgcagg taatcctcgc
901 ggggaacgcg ttcaccgccg ggaaaatcat atttgcagca gtcccaccaa actttccaac
961 tgaaggcttg agccccagcc aggtcactat gttcccccat ataatagtag atgttgggca
1021 attggaacct gtgttgatcc ccttacctga tgttaggaac aatttctatc attacaatca
1081 atcaaatgat tctaccatta aattgatagc aatgctgtat acaccactta gggctaataa
1141 tgctggggat gatgtcttca cagtctcttg tcgagtcctc acgaggccat cccccgattt
1201 tgatttcata ttcttggtgc cacccacagt tgaatcaaga actaaaccat tcaccgtccc
1261 aatcttaact gttgaggaaa tgtccaattc aagattcccc attcctttgg aaaagttgta
1321 cacgggtccc agcagtgctt ttgtcgtcca accacaaaat ggcaggtgca cgactgatgg
1381 cgtgctctta ggtactaccc agctgtctgc tgtcaacatc tgcaccttca gaggggatgt
1441 cacccacatt gcaggcagtc atgactatac aatgaatttg gcttctcaaa attggaacaa
1501 ttatgaccca acagaagaaa tcccagcccc tctgggaact ccagatttcg tgggaaagat
1561 ccaaggcgtg ctcacccaaa ccacaagaga ggatggctcg acccgcgccc acaaagctac
1621 agtgagcact gggagtgtcc actttactcc aaagctgggc agtgttcaat acaccactga
1681 cacaaacaat gattttcaaa ctggccaaaa cacgaaattc accccagtcg gcgtcattca
1741 ggacggtaat aaccatcaaa atgaacccca acaatgggta ctcccaaatt actcaggtag
1801 aactggtcat aatgtacacc tagctcctgc cgttgccccc acttttccgg gtgagcaact
1861 tcttttcttt aggtccacta tgcccggatg tagcgggtat cccaacatga atctggattg
1921 cctactcccc caggaatggg tgcagcactt ctaccaagaa gcagcaccag cacaatctga
1981 tgtggctcta ctgagatttg tgaatccaga tacaggtagg gttctgtttg agtgcaagct
2041 ccataaatca ggctatgtca cagtggctca cactggcccg catgatttgg ttaccccccc
2101 caatggttac tttagatttg attcttgggt caaccagttc tacacacttg cccccatggg
2161 aaatggagcg gggcgtagac gtgcattata atggctggag ctttctttgc tggattggca
2221 tctgatgtcc ttggctctgg acttggttcc ctaatcaatg ctggggctgg ggccatcaac
2281 caaaaagttg aatttgaaaa taacagaaaa ttgcaacaag cttcctttca atttagtagc
2341 aatctacaac aggcttcctt ccaacatgat aaagagatgc tccaagcaca aattgaggcc
2401 actaaaaaat tgcaacaggg tatgatgaag gttaaacagg cgatgctcct agagggtgga
2461 ttctctgaaa cagatgcagc ccgtggggca atcaacgccc ccatgacaaa ggctctggac
2521 tggagcggaa caaggtactg ggctcctgat gccaggacca caacatacaa tgcaggtcgc
2581 ttttccaccc ctcaaccttc gggggcattg ccaggaagaa ctaatcttag ggctactgtc
2641 cccgctcggg gctcctctag tacactttct agtactccca ctgctacttc tgtgtattca
2701 aatcaaactg tttcaacgag acttggttct tcagctggtt ctggtaccag tgtctcgagt
2761 ctcccgtcaa ctgcaaggac taggagctgg gttgaggatc aaaacgtgag gggggctctc
2821 aacacatcat tcgtcacccc accatctagt agatcctcta gccaaggcac agtctcaacc
2881 gtgcctaaag aaattttgga ctcctggact ggcgctttca acacgcgcag gcagcctctc
2941 ttcgctcaca ttcgtaagcg aggggagtca cgggtgtaat gtgaaaagac aaaattgatt
3001 atctttcctt tctttagtgt ctttt
//