Human calicivirus
Typing tool

Complete norovirus genomes

AF414403  GI.3
 GI.P3

Length: 2,926 | 3 CDS 

ORF1: 1..588
ORF2: 572..2209
ORF3: 2209..2856

LOCUS       AF414403                2926 bp ss-RNA     linear   VRL 26-JUL-2016
DEFINITION  Norwalk-like virus NLV/Honolulu/219/1992/US RNA polymerase (orf1)
            gene, partial cds; and capsid protein (orf2) and minor structural
            protein (orf3) genes, complete cds.
ACCESSION   AF414403
VERSION     AF414403.1
KEYWORDS    .
SOURCE      Norwalk-like virus NLV/Honolulu/219/1992/US
  ORGANISM  Norwalk-like virus NLV/Honolulu/219/1992/US
            Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
            Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE   1  (bases 1 to 81)
  AUTHORS   Ando,T., Monroe,S.S., Gentsch,J.R., Jin,Q., Lewis,D.C. and
            Glass,R.I.
  TITLE     Detection and differentiation of antigenically distinct small
            round-structured viruses (Norwalk-like viruses) by reverse
            transcription-PCR and southern hybridization
  JOURNAL   J. Clin. Microbiol. 33 (1), 64-71 (1995)
   PUBMED   7699068
REFERENCE   2  (bases 1 to 2926)
  AUTHORS   Ando,T., Monroe,S.S., Noel,J.S. and Glass,R.I.
  TITLE     A one-tube method of reverse transcription-PCR to efficiently
            amplify a 3-kilobase region from the RNA polymerase gene to the
            poly(A) tail of small round-structured viruses (Norwalk-like
            viruses)
  JOURNAL   J. Clin. Microbiol. 35 (3), 570-577 (1997)
   PUBMED   9041391
REFERENCE   3  (bases 1 to 2926)
  AUTHORS   Ando,T., Noel,J.S. and Fankhauser,R.L.
  TITLE     Genetic classification of 'Norwalk-like viruses.
  JOURNAL   J. Infect. Dis. 181 (Suppl 2), S336-S348 (2000)
   PUBMED   10804147
REFERENCE   4  (bases 1 to 2926)
  AUTHORS   Ando,T., Seto,Y., Noel,J.S., Monroe,S.S., Glass,R.I. and
            Fankhauser,R.L.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-AUG-2001) Viral Gastroenteritis Section/Division of
            Viral and Rickettsial Diseases/National Center for Infectious
            Diseases, Centers for Disease Control and Prevention, 1600 Clifton
            Road, Atlanta, GA 30333, USA
FEATURES             Location/Qualifiers
     source          1..2926
                     /organism="Norwalk-like virus NLV/Honolulu/219/1992/US"
                     /mol_type="genomic RNA"
                     /strain="Hu/NLV/Honolulu/219/1992/US"
                     /db_xref="taxon:171835"
                     /clone="pYS02B"
                     /note="NLV/219; NLV/UK2-12; NLV/S02;
                     group: GI/3"
     gene            <1..588
                     /gene="orf1"
     CDS             <1..588
                     /gene="orf1"
                     /note="nonstructural protein"
                     /codon_start=1
                     /product="RNA polymerase"
                     /protein_id="AAL12961.1"
                     /translation="ILTLCALSEVTGLSPDVIQSQSYFSFYGDDEIVSTDIEFDPIRL
                     TQILKEYGLRPTRPDKTDGPIIVRQQVDGLVFLRRTISKDAIGYQGRLDRNSIERQLW
                     WTRGPNHEDPFETLVPHSQRKIQLISLLGEAALHGEKFYRKIAGRVIQEVKEGGLEIY
                     IPGWQAMFRWMRFHDLSLWTGDRDLLPDYVNDDGV"
     gene            572..2209
                     /gene="orf2"
     CDS             572..2209
                     /gene="orf2"
                     /note="major structural protein"
                     /codon_start=1
                     /product="capsid protein"
                     /protein_id="AAL12962.1"
                     /translation="MMMASKDAPPNMDGTSGAGQLVPEANTAEPISMEPVAGAATAAA
                     TAGQVNMIDPWIMNNYVQAPQGEFTISPNNTPGDILFDLQLGPHLNPFLSHLAQMYNG
                     WVGNMKVKVLLAGNAFTAGKIIISCIPPGFAAQNISIAQATMFPHVIADVRVLEPIEV
                     PLEDVRNVLFHNNDNTPTMRLVCMLYTPLRASGSSSGTDPFVIAGRVLTCPSPDFSLL
                     FLVPPNVEQKTKPFSVPNLPLNTLSNSRVPSLIKSMMVSRDHGQMVQFQNGRVALDGQ
                     LQGTTPTSASQLCKIRGSVFHANGGNGYNPTELDGSPYHAFESPAPIGFPDLGECDWH
                     MEASPTTQFDTGDVIKQINVKQESAFAPHLGTIQADGLSDVSVNTNMIAKLGWVSPVS
                     DGHRGNVDPWVIPRYGSTLTEAAQLAPPIYPPGFGEAIVFFMSDFPIAHGTNGLSVPC
                     TIPQEFVTHFVNEQAPTRGEAALLHYLDPDTHRNLGEFKLYPEGFMTCVPNSSGTGPQ
                     TLPINGVFVFVSWVSRFYQLKPVGTAGPARRLGIRRS"
     gene            2209..2856
                     /gene="orf3"
     CDS             2209..2856
                     /gene="orf3"
                     /codon_start=1
                     /product="minor structural protein"
                     /protein_id="AAL12963.1"
                     /translation="MAQAILGAIAATAAGSAVGAGIQAGTEAALQHQRFQQDLTLQKN
                     SFIHDKEMMGLQVGASTALLQNSLGTRYNMLTKAGMTSTDAARMVVGAPTTRVIDWNG
                     TRIAAPMSTATTLRSGGFVTVPTVYRGGKNKQSIGGGFSNVNYDPSVSSSRTSQWVSS
                     QNSMRSTLEPFHPGALRTTWVTPPGSTSTSTISTVSTVPKFFNTERLPLFANRGK"
     3'UTR           2857..2926
ORIGIN      
        1 atcctaactc tatgtgcatt gtcagaagtc actggcttgt cccctgatgt gatacaatca
       61 caatcttatt tctcatttta tggtgatgat gaaatagtct caacagacat agaatttgac
      121 ccaatcaggt tgacacaaat actgaaggag tatggtttga gacccacaag acctgataaa
      181 actgatggcc caattattgt cagacaacag gtggatggtc tggttttcct ccggcgtacc
      241 atctctaagg acgccattgg ataccaggga cggctcgacc gcaactccat tgaaagacag
      301 ctttggtgga ctcgcgggcc aaaccacgag gacccatttg agacgctagt cccacattcg
      361 cagagaaaga tccaattaat atccctgctg ggtgaagcag cactccatgg tgaaaaattc
      421 tacagaaaga tagctggtag ggttatccaa gaagtcaagg agggggggct tgaaatctac
      481 attcctggtt ggcaggccat gttccgctgg atgcgattcc atgatctgag tttgtggaca
      541 ggagaccgcg atctcctgcc cgattatgta aatgatgatg gcgtctaagg acgccccacc
      601 aaacatggat ggcaccagtg gtgccggcca gctggtacca gaggcaaata cagctgagcc
      661 tatatcaatg gagcctgtgg ctggggcagc aacagctgcc gcaaccgctg gccaagttaa
      721 tatgattgac ccctggataa tgaataatta tgtgcaagcc cctcaaggtg aattcactat
      781 atcgcctaac aatacaccag gtgatatttt gtttgatcta caattaggcc cccatctcaa
      841 tcctttctta tcccatttgg cccaaatgta taatggttgg gttggcaata tgaaagtgaa
      901 ggtcctattg gctggtaatg ccttcacggc tggtaaaata attattagtt gcataccccc
      961 tggctttgct gcacaaaaca tctctattgc tcaggctaca atgttccccc acgtcatagc
     1021 tgacgttagg gttttggaac ctattgaggt gccattggaa gatgtgagga atgtgctgtt
     1081 ccacaacaat gacaacacac caaccatgag gttggtgtgc atgctctaca cccccttgcg
     1141 agccagtggc agctcatctg gaactgaccc ttttgtgatt gctgggcgtg ttttgacgtg
     1201 cccaagccct gattttagcc tcttgttctt ggtccccccc aatgtggaac aaaagactaa
     1261 accttttagt gtcccaaatc taccattgaa taccctttca aattcaagag ttccttctct
     1321 aattaaatca atgatggtat ccagagatca tgggcagatg gttcagtttc aaaacggtag
     1381 ggtcgcccta gatgggcaac tgcaaggcac cacgcccaca tcagctagcc agctgtgcaa
     1441 aatcagaggc agtgtcttcc atgccaatgg tgggaatggg tacaacccaa ctgaactgga
     1501 tgggagccca taccatgcat ttgagagccc tgcgccaata gggtttccag atctaggtga
     1561 gtgtgattgg cacatggagg cctcccctac cacccaattc gatactggtg atgttataaa
     1621 acaaattaat gtcaaacaag aatcagcatt tgctccccac cttggtacta tacaagcaga
     1681 cggcctgagt gatgtgagtg tcaatactaa catgatagct aaattaggat gggtgtcacc
     1741 cgtcagtgat ggacatagag gaaatgtcga tccgtgggtc attccacgat atgggtcgac
     1801 tttgactgag gccgcccaat tagcccctcc aatatatccc ccaggttttg gtgaggccat
     1861 tgtgtttttc atgtcagatt ttcctattgc ccatggtacc aatggcttaa gtgtgccttg
     1921 caccataccc caagaatttg tcactcattt tgtcaatgaa caggccccca ctagagggga
     1981 agcagcccta ctgcattatt tagatcctga cacccataga aatcttggtg agtttaaatt
     2041 ataccctgag ggcttcatga cgtgtgtgcc taattccagt ggcactggtc cacaaaccct
     2101 cccaatcaat ggtgtttttg tttttgtgtc ctgggtttcc agattctatc agttaaagcc
     2161 tgtgggaaca gccggcccgg ctcgtaggct tgggattagg agatcataat ggctcaagct
     2221 atacttggag ccatagcagc aacggcagct ggcagcgctg ttggtgctgg tatacaagct
     2281 ggtactgaag ctgccctaca acaccaaagg ttccagcaag atttgaccct acaaaagaac
     2341 tccttcattc atgacaaaga gatgatgggc ctacaggttg gggcttcaac tgcactcctc
     2401 caaaatagtt tgggcacaag gtacaacatg ttgaccaaag cagggatgac gtccacagat
     2461 gcggcacgca tggttgtggg ggcgcctaca acacgtgtca ttgattggaa tgggactagg
     2521 atcgccgcgc ccatgtcaac cgcaactaca cttaggtctg gtggtttcgt gaccgtgcca
     2581 actgtttata ggggtggtaa aaataaacaa tcaattggtg gtggtttctc taacgtaaat
     2641 tatgatccct cagtttcctc ttctcggact tctcagtggg tttcttcaca aaattcaatg
     2701 cgttccactt tggaaccatt tcacccaggt gccctaagga ccacttgggt tactccacct
     2761 gggtcaactt ctacttctac aatctccaca gtttctactg tgccaaaatt ctttaataca
     2821 gaaagattac ccttattcgc gaacaggggt aagtgatttt gtaatatgaa ttagtgggca
     2881 tcatattcaa tttggaatca attagatatt tagattggca gatgac
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