Typing tool
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Typing tool
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Complete norovirus genomes
| AB933759 | GII.4 Apeldoorn | |
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| GII.P4 Apeldoorn |
ORF1: 1..5100
ORF2: 5081..6703
ORF3: 6703..7509
LOCUS AB933759 7509 bp RNA linear VRL 02-SEP-2015
DEFINITION Norovirus Hu/GII.4/Nagano26/2011/JP genomic RNA, complete genome.
ACCESSION AB933759
VERSION AB933759.1
KEYWORDS .
SOURCE Norovirus Hu/GII.4/Nagano26/2011/JP
ORGANISM Norovirus Hu/GII.4/Nagano26/2011/JP
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1
AUTHORS Sato,H., Yokoyama,M. and Motomura,K.
TITLE Identification of strong evolutionary constraints on viral capsid
protein during divergent evolution of a norovirus pandemic lineage
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7509)
AUTHORS Sato,H., Nakamura,H. and Motomura,K.
TITLE Direct Submission
JOURNAL Submitted (09-MAY-2014) Contact:Kazushi Motomura National Institute
of Infectious Diseases, Pathogen Genomics Center; Gakuen 4-7-1,
Musashi-Murayama, Tokyo 208-0011, Japan
FEATURES Location/Qualifiers
source 1..7509
/organism="Norovirus Hu/GII.4/Nagano26/2011/JP"
/mol_type="genomic RNA"
/strain="Hu/GII.4/Nagano26/2011/JP"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:1498753"
/geo_loc_name="Japan:Nagano"
/collection_date="2011"
CDS 1..5100
/note="contains N-terminal, NTPase, 3A, VPg, 3Cpro and
3Dpol"
/codon_start=1
/product="polyprotein"
/protein_id="BAS30337.1"
/translation="MKMASNDASAAAVADSNNDTVKSSSDGVLSSMAVTFKRALGARP
KQPPPREIPQRPPRPPTPELIKNIPPPPPNGEDDIVVSYSVKDGVSGLPDLSTVRQPE
ESNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
FARVELTPLSLYWRPVYTPQYLISPDALKRLHGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCALSSLFTRPIKDIIGK
LRPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAIVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREV
AKRIAASLTGDQRVGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSSDFSHIKLTLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEFELQGPTLTTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVRTM
PELKQALKNISIKKCQIVYSGSTYTLESDGKGNVKVDRVQSASVQTNNELAGALHHLR
CARIRYYVRCVQEALYSIIQIAGAAFVTTRIVKRMNIQSLWSKPQVENTEETTSKDGC
QNPKDDEVFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVVTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHTRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFERHSRYTYHYDADYSRWD
STQQRAVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTNLSPDTIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLR
EYGLKPTRPDKTEGPLAISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGS
NHEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAEPKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
CDS 5081..6703
/codon_start=1
/product="VP1"
/protein_id="BAS30338.1"
/translation="MKMASSDANPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLATQNWNSYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRADGSTRGHKATVYTGSADFAPKLGRVQFATDTDNDFDANQNTKFTPVGVIQDG
DTAHRNEPQQWVLPSYSGRNSHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6703..7509
/codon_start=1
/product="VP2"
/protein_id="BAS30339.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMRVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGHFSIPQPSGALPGRANLRAAVPARGSSNTPS
NSSTATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARARSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 atgaagatgg cgtctaacga cgcttccgct gccgctgttg ctgatagcaa caacgacacc
61 gtaaaatctt caagtgacgg agtgctttct agcatggctg tcactttcaa acgagccctc
121 ggggcgcggc ctaaacagcc tcccccgagg gaaataccac aaagaccccc acgaccaccc
181 actccagaac tgatcaaaaa tatcccccct cccccaccca acggagagga tgacatagtg
241 gtttcttata gtgtcaaaga tggcgtctct ggtttgcctg atctttccac cgtcaggcaa
301 ccggaagaat ctaatacggc cttcagtgtc cctccactca atcagaggga gaatagagat
361 gctaaggaac cactgactgg aacaattttg gaaatgtggg atggagaaat ctatcattat
421 ggcctgtatg tagagcgagg tcttgtgcta ggtgtgcaca aaccaccagc tgccatcagc
481 ttcgctaggg tcgaactaac accactttcc ttgtactgga gacctgtgta tactccccag
541 tacctcatct ctccagacgc tctcaagaga ctacacggag agacgttccc ctacacagct
601 tttgacaaca actgctacgc cttttgttgt tgggtcctgg acctaaacga ctcgtggctg
661 agtaggagaa tgatccagag aacaactggc ttcttcagac cctaccaaga ttggaatagg
721 aaacccctcc ccactatgga tgactccaag ttaaagaagg tagctaacat attcctgtgt
781 gcactgtctt cgctattcac caggcctata aaagatataa tagggaagct aaggcctctt
841 aacatcctta acatcttggc ctcatgtgat tggacttttg caggcatagt ggagtccttg
901 atactcttgg cagaactctt tggagttttc tggacacccc cagatgtgtc tgcgatgatt
961 gcccccttac tcggtgacta cgagctacag ggacctgagg accttgcagt ggagctcgtc
1021 cctgtagtga tggggggaat tggtttggtg ctaggattca ccaaagagaa gattggaaaa
1081 atgttgtcat ctgctgcatc caccttgaga gcttgtaaag atcttggtgc atatgggcta
1141 gagatcctaa agttggttat gaagtggttc ttcccgaaga aagaggaagc aaatgaactg
1201 gctatagtga gatccatcga ggatgcagtc ctggatctcg aagcaattga aaacaaccat
1261 atgaccacct tgctcaaaga caaagacagt ctggcaacct acatgagaac ccttgacctt
1321 gaggaggaga aagccaggaa actctcgacc aagtctgctt cacctgacat cgtgggcaca
1381 atcaacgccc ttctggcgag aatcgctgct gcacgctctc tggtgcatcg agcgaaggag
1441 gaactttcta gcagaccaag acctgtagtg ttgatgatat caggcagacc aggaataggg
1501 aagacccacc ttgccaggga agtggctaag agaatcgcag cctcccttac aggagaccag
1561 cgtgtaggcc tcgtcccacg caatggcgtc gaccattggg atgcgtacaa gggggagagg
1621 gtcgttctat gggacgacta tggaatgagc aatcctatcc acgatgccct cagattgcaa
1681 gaactcgctg acacttgtcc cctcacccta aactgtgaca ggattgagaa caaaggaaag
1741 gtctttgaca gcgatgtcat cattatcacc actaatttgg ctaacccagc accactggac
1801 tatgtcaact tcgaagcatg ctcgaggcgc atcgacttcc tcgtgtatgc agaagcccct
1861 gaggtcgaaa aggcgaagcg tgacttccca ggccaacccg acatgtggaa gaacgccttc
1921 agttctgatt tctcacacat aaaactaaca ttggctccac agggtggttt cgacaagaac
1981 gggaacaccc cacacgggaa gggcgtcatg aagactctca ccaccggctc ccttattgcc
2041 cgggcatcag ggctactcca tgaaagacta gatgaatttg aactacaggg cccaactctc
2101 accactttca actttgatcg caataaagtg cttgccttta gacaacttgc tgctgaaaat
2161 aaatatgggt tgatggacac aatgaaagtt gggaggcagc tcaaggatgt cagaacaatg
2221 ccagagctca agcaagcact caagaatatt tcaatcaaga agtgccaaat agtgtatagt
2281 ggtagcacct acacacttga gtctgatggc aagggtaatg tgaaggttga cagagttcaa
2341 agcgcctccg tgcagaccaa caatgagctg gctggcgccc tacaccatct aaggtgcgcc
2401 agaataagat actatgtcag gtgtgtccag gaggccctgt attccatcat ccagattgct
2461 ggggctgcat ttgtcaccac gcgcatcgtc aagcgcatga acatacaaag cctatggtct
2521 aagccacaag tggaaaatac agaggagact accagcaagg acgggtgcca aaaccccaaa
2581 gatgatgagg tgttcgtcat ttcatctgac gacatcaaaa ctgagggcaa gaaagggaaa
2641 aacaagactg gccgcggtaa gaagcacaca gccttctcaa gcaaaggtct cagtgatgaa
2701 gagtacgacg agtacaagag gattagagaa gaaaggaatg gtaagtactc catagaagag
2761 taccttcagg acagggacaa atactatgag gaggtggcca ttgccagggc gactgaggaa
2821 gacttctgtg aagaggagga ggccaagatc cggcaaagga tcttcaggcc aacaaggaaa
2881 caacgcaagg aggaaagagc ttctctcggt ttagtcacag gttctgaaat taggaaaaga
2941 aatccagatg atttcaaacc caaggggaaa ctgtgggctg acgatgacag aagtgtggac
3001 tacaatgaga aactcagttt tgaagcccca ccaagcatct ggtcgaggat agtcaacttt
3061 ggttcaggtt ggggattctg ggtctccccc agtttgttca taacatcaac ccatgtcata
3121 ccccaaggag caaaggagtt ctttggagtc cccatcaaac aaattcaggt acataagtca
3181 ggcgaattct gtcgcttgag attcccaaaa ccaatcagga ctgatgtgac gggcatgatc
3241 ttagaagaag gtgcacccga gggaaccgtg gttacactac tcatcaaaag atccactggg
3301 gagctcatgc ccctggcagc taggatgggg acccatgcaa ccatgaaaat ccaagggcgc
3361 actgttggag gtcaaatggg catgcttctg acaggatcca acgccaaaag catggatctg
3421 ggtaccacac caggtgattg tggctgtccc tacatctaca agagaggaaa tgactatgtg
3481 gtcattggag tccacacggc tgccgctcgt gggggcaaca ctgtcatatg tgccacccag
3541 gggagtgagg gagaggctac acttgaaggt ggtgacaata aagggacata ctgtggtgca
3601 ccaatcctag gcccagggag tgccccaaaa cttagcacca agaccaaatt ctggagatcg
3661 tccacagcac cactcccacc tggcacctat gaaccagctt atcttggtgg taaggatccc
3721 agagtcaagg gtgggccttc actacagcag gtcatgaggg atcagctgaa gccattcaca
3781 gagcccaggg gcaagccacc aaagccaagt gtgttggaag ctgctaagaa aaccatcatc
3841 aatgtccttg agcaaacaat tgatccacct gagaaatggt cgttcgcaca agcttgcgcg
3901 tcccttgata agaccacctc cagtggccat ccgcatcaca cgcggaaaaa cgactgctgg
3961 aacggggagt ccttcacagg caagctggca gaccaggctt ccaaggccaa cctgatgttt
4021 gaagaaggga agaacatgac gccagtctac acagctgcgc ttaaggatga attagttaaa
4081 actgacaaaa tttatggcaa gatcaagaag aggcttctct ggggctcgga tttggcgacc
4141 atgatccggt gtgctcgagc attcggaggc ctaatggatg aactcaaagc gcactgtgtc
4201 acacttccca ttagagttgg tatgaatatg aatgaggatg gccccatcat cttcgagagg
4261 cactccaggt acacgtacca ctatgatgct gattactctc gatgggattc aacacaacag
4321 agagccgtgt tggcagcagc tctagaaatc atggttaagt tctccccaga accacatttg
4381 gcccaggtag tcgcagaaga ccttctttct cctagcgtgg tggacgtggg tgatttcaca
4441 atatcaatta acgagggcct tccttctggg gtgccctgca cctcccaatg gaactccatc
4501 gcccactggc ttctcaccct ctgtgcgctc tctgaagtta caaacttgtc tcctgacacc
4561 atacaagcta actccctctt ctctttttat ggtgatgatg aaattgttag cacagacata
4621 aaattggacc cagaaaagtt gacagcaaag ctcagggaat atgggttaaa accaacccgc
4681 cccgacaaga ctgaaggacc ccttgccatc tctgaagact tgaatggcct gactttcttg
4741 cggagaactg tgacccgcga cccagctggt tggtttggaa aactggagca gagttcaata
4801 ctcaggcaaa tgtactggac taggggttcc aaccatgaag acccatttga aacaatgatt
4861 ccacactccc aaagacccat acaattgatg tccctactgg gggaggccgc actccacggc
4921 ccagcattct acagcaaaat cagcaagtta gtcattgcag aacctaaaga aggtggcatg
4981 gatttttacg tgcccagaca agagccaatg ttcagatgga tgagattctc agatctgagc
5041 acgtgggagg gcgatcgcaa tctggctccc agttttgtga atgaagatgg cgtcgagtga
5101 cgccaaccca tctgatgggt ctacagccaa cctcgtccca gaggtcaaca atgaggttat
5161 ggctttggag cccgttgttg gtgccgccat tgcggcacct gtagcgggcc aacaaaatgt
5221 aattgacccc tggattagaa ataattttgt acaagcccct ggtggagagt tcacagtatc
5281 ccctaggaac gctccaggtg aaatactatg gagcgcgccc ctaggccctg atttgaatcc
5341 ttacctttcc catttggcca gaatgtacaa tggttatgca ggtggttttg aagtgcaggt
5401 aatcctcgcg gggaacgcgt tcaccgccgg aaaaatcata tttgcagcag tcccaccaaa
5461 tttcccaact gaaggcttga gccccagcca ggttactatg ttcccccaca taatagtaga
5521 tgttaggcaa ctggaacctg tgttgatccc cttacccgat gttaggaata atttctatca
5581 ctacaatcaa tcaaatgacc ccaccatcaa attgatagca atgttgtaca caccacttag
5641 ggctaataat gctggggacg atgtcttcac agtttcttgt cgggtactca cgagaccatc
5701 ccccgatttt gatttcatat ttttagtgcc acccacagtt gaatcaagaa ctaaaccatt
5761 ctctgtccca attttaactg ttgaggagat gaccaattca agattcccca ttcctttgga
5821 aaagctgttc acgggtccca gcagtgcctt tgttgttcaa ccacaaaacg gcaggtgcac
5881 gactgatggc gtgctcctag gtaccaccca actgtctcct gtcaacatct gcaccttcag
5941 aggggatgtc acccatatta caggtagtcg taactacaca atgaatttgg ctactcaaaa
6001 ttggaacagt tatgacccaa cagaagaaat cccagcccct ctaggaactc cagatttcgt
6061 gggaaagatc caaggtgtgc tcacccaaac cacgagggca gatggctcga cccgtggaca
6121 caaagctaca gtgtacactg ggagcgccga ctttgctcca aaactgggta gagttcaatt
6181 tgccactgac acagacaatg attttgatgc taaccaaaac acaaagttca ccccagtcgg
6241 tgtcatccag gatggtgata ctgcccaccg aaatgaaccc caacaatggg tgctcccaag
6301 ttactcaggt agaaatagtc acaatgtgca cctggccccc gctgtagccc ccacttttcc
6361 gggtgagcaa cttctcttct tcagatccac tatgcccgga tgcagcgggt accccaacat
6421 ggatttggac tgtctgctcc cccaggaatg ggtgcagtat ttctatcaag aggcagcccc
6481 agcacaatct gatgtggctc tgctaagatt tgtgaatcca gacacaggta gggttttgtt
6541 tgagtgtaag cttcataaat caggctatgt tacagtggct cacaccggcc aacatgatct
6601 ggttatcccc cccaatggtt attttagatt tgattcctgg gtcaaccagt tctacacact
6661 tgcccccatg ggaaatggaa cggggcgtag acgtgcatta taatggctgg agctttcttt
6721 gctggattgg catctgatgt ccttggatcc gggcttggtt ctctgatcaa tgccggggct
6781 ggggccatca accaaaaagt tgaatttgaa aataacagaa aattgcaaca agcttccttc
6841 caattcagta gcaatctaca acaggcttcc tttcaacatg ataaagagat gctccaagca
6901 caaattgagg ccaccaaaaa gttgcaacag gaaatgatga gagttaaaca ggcaatgctc
6961 ctagagggtg gattctctga gacagatgca gcccgtgggg caatcaacgc ccccatgaca
7021 aaggctttgg actggagtgg gacaaggtac tgggctcccg atgctaggac tacaacatac
7081 aatgcaggcc acttttccat ccctcaaccc tcgggggcac tgccagggag agctaatctt
7141 agggctgctg tccccgctcg gggctcctcc aacacacctt ctaactcttc tactgctacc
7201 tctgtgtact caaatcaaac cacttcaacg agacttggtt ctacagctgg ttctggtacc
7261 agtgtctcga gcctcccgtc aactgcaagg gctaggagct gggttgagga tcaaaatagg
7321 aatttgtcac ctttcatgag gggggcccac aacatatcgt ttgtcacccc accatctagc
7381 agatcctcta gccaaggcac agtctcaacc gtgcccaaag aagttttgga ctcctggact
7441 ggcgctttca atacgcgcag gcagcctctc ttcgctcaca ttcgtaagcg aggggagtca
7501 cgggcgtaa
//