Typing tool
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Typing tool
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Complete norovirus genomes
| AB933728 | GII.4 Den Haag | |
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| GII.P12 |
ORF1: 1..5097
ORF2: 5081..6700
ORF3: 6700..7467
LOCUS AB933728 7467 bp RNA linear VRL 02-SEP-2015
DEFINITION Norovirus Hu/GII.4/Akita5/2009/JP genomic RNA, complete genome.
ACCESSION AB933728
VERSION AB933728.1
KEYWORDS .
SOURCE Norovirus Hu/GII.4/Akita5/2009/JP
ORGANISM Norovirus Hu/GII.4/Akita5/2009/JP
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1
AUTHORS Sato,H., Yokoyama,M. and Motomura,K.
TITLE Identification of strong evolutionary constraints on viral capsid
protein during divergent evolution of a norovirus pandemic lineage
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7467)
AUTHORS Sato,H., Nakamura,H. and Motomura,K.
TITLE Direct Submission
JOURNAL Submitted (09-MAY-2014) Contact:Kazushi Motomura National Institute
of Infectious Diseases, Pathogen Genomics Center; Gakuen 4-7-1,
Musashi-Murayama, Tokyo 208-0011, Japan
FEATURES Location/Qualifiers
source 1..7467
/organism="Norovirus Hu/GII.4/Akita5/2009/JP"
/mol_type="genomic RNA"
/strain="Hu/GII.4/Akita5/2009/JP"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:1498722"
/country="Japan:Akita"
/collection_date="2009"
CDS 1..5097
/note="contains N-terminal, NTPase, 3A, VPg, 3Cpro and
3Dpol"
/codon_start=1
/product="polyprotein"
/protein_id="BAS30244.1"
/translation="MKMASNDAFAAAAANSNNDTAKSSSDRMFSNMAVTFKRALGARH
KQPPPKEIPQRPPRPPTPELVKKIPPPPPNGEDEPVVSYSAKDGVSGLPELTTVRQPE
ETNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAVS
LARIELAPLSLYWRPVYTPQYLISPDTLKKLHGESFPYTAFDNNCYAFCCWVLDLNDS
WLCRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVADVFLCALSSLFTRPIKDIIGK
VKPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSALIAPLLGDYELQGPED
LAVELVPVVMGGIGLVLGFTKEKVGKMLSSAATTLRACKDLGAYGLEILKLVMKWFFP
KKEETNELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDVEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVVMISGKPGIGKTHLARAL
AKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSPDFSHIKLTLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
TGLLHERLDEYELQGPAPTTFNFDRNKVLAFRQLAAENKYGLLDTMRVGKQLKDVKTM
PELKQALKNVAIKSCQIVYGGCTYRLESDGKGEVKIDKVQNATVQTNNELDGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTSRIVKRMNIQDLWSKPQVEDTEETTSKDGC
PKPKDDDEFIVSSDDLKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNERLDFEAPPSVWSRIVNFGSGWGFWVSP
SLFITSTHVIPKGAQEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVASLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGGEGEATLEGGDNKGTYCGAPILG
PGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPEKWTFAQACASLDKTTSSGHPHHLRKNDCW
NGESFTGKLADQASKANLMYEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMEELKAHCVTLPVRVGMNMNEDGPIIFERHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVKFSPEPHLAQKVAEDLLSPSVMDVGDFKISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVITEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGV"
CDS 5081..6700
/codon_start=1
/product="VP1"
/protein_id="BAS30245.1"
/translation="MKMASNDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAIPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQTKESTIKLVAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
SVESRTKPFTVPILTVEEMTNSRFPIPLERLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTRVSTTHVYEMNLASQNWNNYDPTEEVPAPLGTPDFVGKIQGVL
TQTTRTDGSTRAHKATVSTGAADFTPKLGSIRFETTTNRDLETHQNTKFTPVGVIQDG
DNHQNEPQQWRLPGYAGRDAHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMNLDC
LLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYLTVAHTGPYDLVI
PPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6700..7467
/codon_start=1
/product="VP2"
/protein_id="BAS30246.1"
/translation="MAGAAVAGLASDVLSSGLGSLINAGAGVINQKVDFEHNRQLQQA
SFAFSNNQQQASFQHDKEMLQAQIEATKKLQQGMMKIKQAMLLEGGFSATDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFATPLPSGASPGRANPRATAPARGSPSTPS
NASTATSVYSNQTVSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRSLSSFSSRSSSQ
GTVSTVPKGVLDSWTGAFNTRRQPLFAYIRTRGESRV"
ORIGIN
1 atgaagatgg cgtctaacga cgctttcgct gccgctgctg ctaacagcaa caacgacacc
61 gcaaaatctt caagtgacag aatgttttct aacatggctg tcacttttaa acgagccctt
121 ggggcgcggc acaaacagcc tcccccgaag gaaataccac aaagaccccc acgaccaccc
181 accccagaac tggtcaaaaa gatccctcct cccccaccca acggggagga tgaaccagtg
241 gtttcttaca gcgccaaaga tggcgtttcc ggtttgcctg agctcaccac tgtccggcag
301 ccggaagaga ccaacacggc gttcagcgtt cccccactca accagaggga gaacagggac
361 gccaaggagc cactaaccgg aacgatcctg gaaatgtggg acggggagat ctaccattac
421 ggtctgtatg tggaacgagg ccttgtactc ggtgtgcaca aaccaccagc tgccgtcagc
481 ctcgccagga ttgaattggc tccactctcc ctgtactgga gaccagtgta cacaccacag
541 tatctcatct ctccagacac tcttaagaaa ctgcacggag agtcgttccc ctacacagcc
601 tttgataaca actgctatgc cttctgttgt tgggtcctgg acctaaacga ctcgtggttg
661 tgcaggagaa tgatccagag gacaactggt ttcttcagac cttaccaaga ctggaacagg
721 aaacccctcc ccaccatgga tgactccaag ctgaagaagg tagccgacgt attcttgtgc
781 gcgctatctt cgctgttcac taggcccatc aaagatataa taggaaaagt gaaaccgctt
841 aacatcctta acatcttggc ctcatgtgat tggacttttg caggcatagt ggaatctttg
901 atcctcttgg cagagctctt tggagttttc tggacacccc cagatgtgtc tgcgttgatc
961 gcccccttac taggtgatta cgaactgcag ggtcctgagg accttgcggt ggaactcgtt
1021 ccagtggtga tgggggggat aggtttggtg ctgggattca ccaaagagaa ggtcgggaaa
1081 atgttgtcat ctgctgcaac caccttaaga gcttgcaaag accttggtgc atacggactg
1141 gaaatcctaa aattggttat gaagtggttc ttcccaaaga aagaggaaac aaatgagctg
1201 gctatggtga gagccatcga ggatgcggtg ctggatctcg aggcaatcga gaacaaccac
1261 atgaccaccc tcctcaaaga caaagacagc ttggcaacct acatgagaac cctcgacgtc
1321 gaggaggaga aggccaggaa gctctcaacc aagtctgctt cacctgacat cgtgggcaca
1381 atcaacgctc tcctggcgag aatcgccgct gcacgttccc tggtgcatcg ggcgaaagag
1441 gaactctcca gcaggccaag gcctgtcgtt gtcatgatat caggcaaacc agggataggg
1501 aaaactcacc ttgccagggc actggccaag aagatcgcag cttcgctcac aggagaccag
1561 cgtgtaggcc tcatcccccg taacggtgtt gatcactggg atgcgtataa gggggaaaga
1621 gtcgtcctat gggacgatta tggaatgagc aatcccatcc acgacgccct caggctacag
1681 gaacttgctg acacctgccc cctcacgcta aactgtgaca gaattgagaa caaaggaaag
1741 gtctttgaca gtgatgccat aatcatcacc actaatctgg ccaacccagc tccattggac
1801 tatgtcaact ttgaagcatg ctcgaggcgc atcgacttcc tcgtgtacgc agaagcccct
1861 gaggtcgaga aggcaaagcg tgatttccca ggtcaacctg acatgtggaa gaacgcattc
1921 agccctgact tctcgcatat aaaattgacg ctggccccgc aaggtggctt cgacaagaac
1981 ggaaacaccc cgcacgggaa aggcgtcatg aaaaccctca ccactggttc cctcatcgcc
2041 cgagcaacag ggctactcca tgagaggtta gatgagtatg agctgcaggg cccagccccc
2101 accaccttca actttgaccg caacaaggtg cttgcattca gacagcttgc tgccgaaaac
2161 aagtacgggt tgttggacac aatgagagtt ggaaaacagc tcaaggatgt caagactatg
2221 ccagagctca aacaagcact caagaacgtt gcaatcaaga gttgtcagat agtgtatggt
2281 ggctgcactt ataggcttga gtctgacggc aagggtgaag tgaaaattga caaagttcag
2341 aacgccactg tacagaccaa caatgagctt gacggcgccc tacaccacct taggtgtgcc
2401 agaatcaggt attatgtcaa gtgtgtccag gaggccctgt attctatcat ccaaattgct
2461 ggggctgcat ttgtgacctc gcgcattgtc aagcgcatga acatacaaga cctctggtcc
2521 aagccacagg tggaggacac agaggagacc actagcaagg atgggtgccc aaaacccaag
2581 gatgatgacg agttcattgt ctcatccgat gacctcaaaa ccgagggcaa aaaggggaag
2641 aacaagtctg gccgtggtaa gaagcacacg gcattctcaa gtaaaggtct cagtgatgag
2701 gagtatgatg agtacaaaag aatcagagaa gagaggaacg gcaagtactc catagaggaa
2761 taccttcagg acagagacaa gtactatgag gaggtggcca tcgccagggc aaccgaagag
2821 gacttctgtg aggaagaaga ggccaagatc cggcaaagga ttttcaggcc aacaaggaaa
2881 caacgcaaag aggagagggc ctccctcggc ttggtcacag gctctgaaat caggaagagg
2941 aacccagacg acttcaagcc caaaggaaaa ctgtgggctg atgacgacag gagtgtcgac
3001 tacaatgaga gactcgactt tgaagcccca ccaagcgtct ggtcgaggat agtcaacttt
3061 ggttcaggtt ggggcttttg ggtttccccc agtttgttca taacatcaac tcatgtcata
3121 cccaagggcg cacaggagtt ctttggtgtc cccatcaaac aaattcaaat acacaaatcg
3181 ggtgaattct gtcgcttgag gtttccaaaa ccaatcagaa ctgacgtgac aggcatgatc
3241 ttagaggaag gtgcacccga ggggaccgtg gcctcactac tcatcaagag gccaactgga
3301 gaactcatgc ccttggcagc cagaatggga acccatgcaa ccatgaagat ccaagggcgc
3361 actgtcggag gtcagatggg catgctccta acaggatcta atgccaagag catggacctg
3421 ggcaccacac caggtgactg tggctgcccc tacatctaca agagggggaa tgactatgta
3481 gtcattggag tccacacagc tgccgcccgt ggaggaaaca ctgtcatatg tgccacccag
3541 gggggcgaag gagaagccac acttgagggc ggtgacaaca aggggaccta ctgcggtgca
3601 ccaatcttag gtccaggaag tgcaccgaag ctcagcacca agactaaatt ctggaggtca
3661 tccacggcac cacttccacc tggtacctat gagccagcct acctcggcgg caaggacccc
3721 agagttaagg gtggcccttc attacaacaa gttatgaggg accagctgaa accattcact
3781 gaacccaggg gaaaaccacc aaaaccaagt gtgttagaag ctgccaagaa aaccatcatt
3841 aatgtccttg aacaaacaat tgacccacct gaaaagtgga catttgcgca ggcatgtgca
3901 tcccttgaca agaccacttc cagcggtcac ccccaccact tgcggaaaaa tgactgctgg
3961 aacggggagt cctttacagg caagttggca gaccaggctt ccaaggccaa cctgatgtac
4021 gaggagggaa agaacatgac cccagtctac acgggtgcgc ttaaggacga gctggtcaag
4081 actgacaaga tttatggcaa gatcaaaaag aggcttctct ggggttcgga cctggcgacc
4141 atgatccggt gcgctcgagc attcgggggc ctgatggagg aactcaaggc acattgtgtc
4201 acactacctg tcagagtggg tatgaatatg aatgaggatg gtcctatcat ctttgagaga
4261 cactccagat ataaatacca ttatgatgct gattactccc ggtgggattc aactcaacaa
4321 agagccgtgt tggcagcggc cttggaaatc atggtcaaat tctccccaga gccgcatctg
4381 gcccaaaagg ttgcagaaga ccttctttct cccagcgtga tggacgtggg tgatttcaaa
4441 atatcaatca atgagggtct cccctccggg gtgccctgca cctctcagtg gaactccatt
4501 gcccactggc tcctcactct gtgtgcactc tctgaggtta caaacctgtc ccctgacatc
4561 atccaggcca actcactctt ctctttctac ggtgatgatg aaattgtgag cacagacata
4621 aaattggacc cggaaaagct aacagcaaaa ctcaaggaat acgggttgaa accgacccgt
4681 cctgacaaga ctgagggacc cctcgtcatc actgaagacc tgaacggcct aaccttcctg
4741 cggaggaccg tgacccgcga tccagcaggc tggtttggaa agttggaaca gagttcaata
4801 ctcagacaaa tgtactggac taggggcccc aaccatgaag acccatctga aacaatgata
4861 ccacactccc aaaggcccat acaattgatg tctctgctgg gtgaggctgc actccacggt
4921 ccagcattct acagcaaaat cagcaaactg gtcattgcag agttgaagga aggtggcatg
4981 gatttttacg tgccaagaca agagccaatg ttcagatgga tgagattctc agatctgagc
5041 acgtgggagg gcgatcgcaa tctggctccc agttttgtga atgaagatgg cgtctaacga
5101 cgccaaccca tctgatgggt ccgcagccaa cctcgtccca gaggtcaaca atgaggttat
5161 ggctttggag cccgttgttg gtgccgctat cgcggcaccc gtagcgggcc aacaaaatgt
5221 aattgacccc tggattagga acaattttgt acaagcccct ggtggagagt tcacagtgtc
5281 ccctagaaac gctccaggtg aaatactatg gagcgcgccc ttaggccctg atctgaaccc
5341 atacctttcc cacctggcca gaatgtacaa tggttatgca ggtggctttg aagtgcaggt
5401 aatccttgcg gggaacgcgt tcaccgcagg taaaatcata tttgcagcaa tcccaccaaa
5461 ttttccaact gaaggcttga gccccagtca ggtcactatg ttcccccata tagtagtaga
5521 tgttaggcaa ttggaacctg tattgatccc cttacctgat gttaggaaca atttctacca
5581 ctacaatcaa acaaaagagt ccaccatcaa attggtagca atgctgtaca caccacttag
5641 ggctaataat gctggggatg atgtcttcac agtctcttgt cgagtcctca cgagaccatc
5701 ccccgatttt gatttcatat ttctggtgcc accctcagtt gaatcaagaa ccaaaccatt
5761 caccgtccca attttaactg ttgaggaaat gaccaattca agattcccca tacctttgga
5821 aagattgttc acgggtccta gcagtgcctt tgtcgtccag ccacaaaatg gcaggtgcac
5881 gactgatggc gtgctcttag gcaccaccca actgtccccc gtcaacatct gcaccttcag
5941 aggggacgtc acccgagttt caaccactca tgtttatgaa atgaatttgg cttctcaaaa
6001 ttggaataat tatgacccaa cagaagaagt cccagcccct ctgggaactc cagattttgt
6061 gggaaagatc caaggcgtgc tcacccaaac cacaaggaca gacggttcga cccgcgccca
6121 caaagcaacg gtgagcactg gggctgccga cttcactcca aaactgggca gcatccggtt
6181 cgaaaccacc acgaaccgtg atcttgaaac tcaccaaaac acaaagttca ccccagtcgg
6241 tgtcatccag gatggtgaca accaccaaaa tgaaccccaa caatggagac tcccaggtta
6301 cgcaggtagg gatgctcaca acgtgcacct agcccctgcc gtagccccca ctttcccggg
6361 tgagcaactc cttttcttca gatccaccat gcccggatgc agtgggtatc ccaacatgaa
6421 tttggattgt ctactccccc aagaatgggt gcagcacttc taccaagagg cagccccagc
6481 acaatctgat gtggctctgt tgagattcgt gaatccagac acgggtagag ttctgtttga
6541 gtgcaagctt cacaaatcag gctatctcac agtggcccac accggcccgt atgatttggt
6601 catccccccc aatggctact tcagatttga ttcgtgggtc aaccagttct acactcttgc
6661 ccccatggga aatggaacgg ggcgtagacg tgcattataa tggctggagc tgccgttgct
6721 ggattggcat ctgatgtcct tagctctgga cttggttctc taatcaatgc tggggctggg
6781 gtcattaacc aaaaagttga ttttgaacac aacagacaat tgcaacaagc ttcctttgct
6841 ttcagcaaca atcaacaaca ggcttccttt caacatgaca aagagatgct ccaagcacaa
6901 attgaggcca ccaaaaagtt acagcagggt atgatgaaaa tcaaacaggc aatgctccta
6961 gagggtgggt tctctgcaac agatgcggcc cgtggggcaa tcaacgcccc catgacaaag
7021 gctttggact ggagcggaac aaggtactgg gctcctgatg ctagaactac aacatacaat
7081 gcaggccgct ttgccacccc tctaccttcg ggggcatcgc caggaagagc taaccccagg
7141 gctactgccc ccgctcgggg ctcccccagc actccttcta atgcttctac tgctacttct
7201 gtctattcaa atcaaactgt ttcaacgaga cttggttcta cagctggttc tggcaccagt
7261 gtctcgagtc tcccgtcaac tgcaaggact aggagttggg ttgaggacca aaacaggagt
7321 ttgtcatctt tctccagtag gtcctctagc cagggcacag tctcaaccgt gcccaaagga
7381 gttttggact cctggactgg cgctttcaac acgcgcaggc agcctctctt cgcttacatt
7441 cgtacgcgag gggagtcacg ggtgtaa
//