Typing tool
|
|
|
|
|
|
Typing tool
|
Complete norovirus genomes
| AB933710 | GII.4 Den Haag | |
|
|---|---|---|---|
| GII.P4 Den Haag |
ORF1: 1..5097
ORF2: 5081..6703
ORF3: 6703..7509
LOCUS AB933710 7509 bp RNA linear VRL 02-SEP-2015
DEFINITION Norovirus Hu/GII.4/Aomori4/2011/JP genomic RNA, complete genome.
ACCESSION AB933710
VERSION AB933710.1
KEYWORDS .
SOURCE Norovirus Hu/GII.4/Aomori4/2011/JP
ORGANISM Norovirus Hu/GII.4/Aomori4/2011/JP
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1
AUTHORS Sato,H., Yokoyama,M. and Motomura,K.
TITLE Identification of strong evolutionary constraints on viral capsid
protein during divergent evolution of a norovirus pandemic lineage
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7509)
AUTHORS Sato,H., Nakamura,H. and Motomura,K.
TITLE Direct Submission
JOURNAL Submitted (09-MAY-2014) Contact:Kazushi Motomura National Institute
of Infectious Diseases, Pathogen Genomics Center; Gakuen 4-7-1,
Musashi-Murayama, Tokyo 208-0011, Japan
FEATURES Location/Qualifiers
source 1..7509
/organism="Norovirus Hu/GII.4/Aomori4/2011/JP"
/mol_type="genomic RNA"
/strain="Hu/GII.4/Aomori4/2011/JP"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:1498704"
/geo_loc_name="Japan:Aomori"
/collection_date="2011"
CDS 1..5097
/note="contains N-terminal, NTPase, 3A, VPg, 3Cpro and
3Dpol"
/codon_start=1
/product="polyprotein"
/protein_id="BAS30190.1"
/translation="MKMASNDASAAAVANSNNDIAKSSSDKMFSNMAVTFKRALGARP
KQPPPREIPQRPPRPPTPELVKKIPPPPPNGEDEVVVSYNAKDGVSGLPELSTVMAPE
ETNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LAKVELTPLSLFWRPVYTPQYLISPDTLKKLHGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDVIGK
LRPLNIINILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDFELQGSED
LVVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREV
AKRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLGYAEAPEVEK
AKRDFAGQPDMWKNAFSSDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGRQLKDVKTM
PELKQALKNISIKKCQIVYNGCTYTLESDGKGNVKVDRVQSTSVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIIKRVNIQDLWSKPQVENTEEATNKDGC
PKPKDTEEFVISSDDIKTEGKKGKNKAGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVVTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGGEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKDGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPSESMIPHSQRPIQLMSLLGEAALHGPTFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGV"
CDS 5081..6703
/codon_start=1
/product="VP1"
/protein_id="BAS30191.1"
/translation="MKMASNDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGEDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHIAGSRNYTMNLASLNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTKGDGSTRGHKATVYTGSAPFTPKLGSVQFGTDTENDFETHQNTKFTPVGVIQDG
GTTHRNEPQQWVLPSYSGRNVPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6703..7509
/codon_start=1
/product="VP2"
/protein_id="BAS30192.1"
/translation="MAGAFFAGLASDVLSSGLGSLINAGAGAINQKIDFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARITTYNAGRFSTPQPSGELPGRINPRTPTPARGSPSTFS
NASTASSIYSNQTVSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRRRGESRV"
ORIGIN
1 atgaagatgg cgtctaacga cgcttccgct gccgctgttg ctaacagcaa caacgacatc
61 gcaaaatctt caagtgacaa aatgttctct aacatggctg tcacttttaa acgagccctc
121 ggggcgcggc ctaaacagcc ccccccgagg gaaataccac aaagaccccc acgaccacct
181 actccagaac tggtcaaaaa gatccctcct cccccgccca acggagagga tgaagtagtg
241 gtttcttata atgccaaaga tggcgtttcc ggtttacccg agctttccac cgtcatggca
301 ccggaagaaa ccaacacggc cttcagtgtc cctccactca atcagaggga gaacagggat
361 gctaaggaac cactgactgg aacaattctg gaaatgtggg acggagaaat ctaccattat
421 ggcctgtatg ttgagcgagg tcttgtgctg ggtgtgcaca aaccaccagc tgccattagc
481 ctcgccaagg tcgaactaac accactctcc ttgttctgga gacctgttta cactcctcag
541 tacctcatct ctccagacac tctcaagaaa ttacacggag aaacattccc ttacacagcc
601 ttcgacaaca attgctatgc cttttgttgc tgggttctgg atctaaacga ctcgtggctg
661 agtaggagaa tgatccagag aacaactggc ttcttcagac cctaccaaga ttggaatagg
721 aaacccctcc ccactatgga tgattccaaa ttaaagaagg tagctaacat attcctgtgc
781 accctgtctt cgctatttac caggcccata aaagacgtaa tagggaagtt aaggcccctc
841 aacatcatca acatcctggc ttcatgtgat tggactttcg caggcatagt ggagtccttg
901 atactcttgg cagaactctt tggagtcttc tggacacccc cagatgtgtc tgcgatgatt
961 gcccccttac tcggtgattt tgagttacaa ggatctgagg accttgtagt ggagctcgtc
1021 cctgtagtaa tggggggaat tggtttggtg ctaggattca ccaaagagaa gattggaaaa
1081 atgttgtcat ctgctgcatc taccttgaga gcttgtaaag atcttggtgc atatgggcta
1141 gagatcctaa agttagtcat gaagtggttc ttcccgaaga aagaggaagc aaatgaactg
1201 gctatggtga gatccatcga ggatgcagta ctggaccttg aggcaattga aaacaaccat
1261 atgaccacct tgctcaaaga caaagacagc ctggcaacct atatgagaac ccttgacctc
1321 gaggaagaga aagccagaaa actctcaacc aagtctgctt cacctgacat cgtgggcaca
1381 atcaacgctc ttctggcgag aatcgccgct gcacgctccc tggtgcaccg agcgaaggaa
1441 gaactttcca gcagaccaag acctgtagtc ttgatgatat caggcagacc aggaataggg
1501 aagacccacc ttgctaggga agtggctaag agaatcgcag cctccctcac aggagatcag
1561 cgtgtgggtc tcatcccacg caatggcgtc gatcactggg atgcgtacaa gggggagagg
1621 gtcgtcctat gggacgacta tggaatgagc aatcccatcc acgacgccct caggttgcaa
1681 gaactcgctg acacttgccc cctcactcta aattgtgaca ggattgagaa taaaggaaag
1741 gtctttgaca gcgatgtcat catcatcact actaacctgg ccaacccagc accactggac
1801 tatgtcaact ttgaagcgtg ctcgaggcgc atcgatttcc tcgggtatgc agaagccccc
1861 gaggtcgaaa aggcaaagcg tgacttcgcg ggccaacctg acatgtggaa aaacgctttc
1921 agttctgatt tctcacacat aaaactggcg ctggctccac aaggtggctt tgataagaac
1981 gggaacaccc cacacgggaa gggtgtcatg aagactctca ccactggctc cctcattgcc
2041 cgggcatcag ggctgctcca tgagagattg gatgagtttg aactacaggg cccagctctt
2101 accaccttca actttgaccg caacaaagtg cttgccttca ggcagcttgc tgctgagaac
2161 aaatacgggt tgatggatac aatgagagtt gggaggcagc tcaaggatgt caaaaccatg
2221 ccagaactta aacaagcact caaaaatatc tcaatcaaga agtgccagat tgtgtataat
2281 ggttgcacct acacacttga gtctgatggt aagggcaatg tgaaagttga cagagttcag
2341 agcacctccg ttcaaaccaa caatgagctg gctggcgccc tgcaccatct aaggtgcgcc
2401 agaatcaggt actatgtcaa gtgtgttcag gaggccctgt attctatcat ccagattgct
2461 ggggctgcat ttgtcaccac gcgcatcatc aagcgtgtga acatccaaga cttatggtcc
2521 aagccacaag tggaaaacac agaggaggct accaacaagg acgggtgccc aaaacccaaa
2581 gatactgagg agtttgtcat ttcatctgac gacattaaaa ctgagggtaa gaaagggaag
2641 aacaaggctg gccgtggcaa gaagcacaca gccttctcaa gtaaaggtct cagtgatgaa
2701 gagtatgatg agtacaagag aattagagag gagaggaatg gcaagtactc catagaagag
2761 tacctacagg acagggacaa atactatgag gaggtggcca ttgccagggc gaccgaggaa
2821 gacttctgtg aagaggagga ggccaagatc cggcaaagga tcttcagacc aacaaggaaa
2881 caacgcaagg aagaaagagc ttctctcggt ttagtcacag gttctgaaat taggaaaagg
2941 aacccagaag acttcaagcc taaggggaaa ctgtgggctg acgatgacag aagtgtggac
3001 tacaatgaaa aactcagttt tgaggcccca ccaagcatct ggtcaaggat agtcaacttt
3061 ggctcaggtt ggggcttctg ggtctccccc agcctgttca taacatcaac ccacgtcata
3121 ccccagggcg caaaggagtt ctttggagtc cccatcaaac aaattcaggt gcacaagtca
3181 ggcgaattct gtcgcttgag gttcccaaaa ccaatcagga ctgatgtgac tggcatgatc
3241 ttggaagaag gtgcgcccga aggcaccgtg gtcacactac tcatcaaaag gtctactgga
3301 gaactcatgc ccctagcagc tagaatgggg acccacgcaa ccatgaagat tcaagggcgc
3361 actgttgggg gtcagatggg catgcttctg acaggatcca acgccaaaag catggatcta
3421 ggcaccacac caggtgattg cggctgtccc tacatctaca agagaggaaa tgactatgtg
3481 gtcattggag tccacacggc tgccgctcgt gggggaaaca ccgtcatatg tgccacccag
3541 gggggtgagg gggaagctac acttgaaggt ggtgacagta agggaacata ctgtggtgca
3601 ccaatcctag gcccagggag tgccccaaaa cttagcacca aaaccaaatt ctggagatca
3661 tccacagcac cactcccacc tggcacctat gaaccagcct acctaggtgg caaggacccc
3721 agggtcaagg atggcccctc gttgcagcaa gtcatgaggg accagctgaa accatttaca
3781 gagcctaggg gtaagccacc aaagccaagc gtgttggaag ctgccaagaa aaccatcatc
3841 aatgtccttg aacaaacaat tgacccacct gagaagtggt cgttcgcaca agcttgcgcg
3901 tcccttgaca agaccacttc tagcggccat ccgcaccaca tgcggaaaaa cgactgctgg
3961 aacggggaat ccttcacagg caagctggca gaccaggctt ccaaggccaa cctgatgttt
4021 gaagaaggga agaacatgac cccagtctac acaggtgcac ttaaggatga actagtcaaa
4081 actgacaaaa tttatggtaa gatcaagaag aggcttctct ggggctcgga tttagcaacc
4141 atgatccggt gtgctcgagc attcggaggc ctaatggatg aactcaaagc acactgtgtt
4201 acacttccta tcagagttgg tatgaatatg aatgaggatg gccccatcat cttcgagaag
4261 cattccaggt acagatacca ctatgatgct gattactctc ggtgggattc aacacaacag
4321 agagccgtgc tggcagctgc tctagaaatc atggttaaat tctcctcaga accacatttg
4381 gctcaggtag tcgcagaaga ccttctttct cctagcgtgg tggatgtggg tgacttcaca
4441 atatcaatca acgagggtct cccctctggg gtgccctgca cctcccaatg gaactccatc
4501 gcccactggc ttctcactct ctgtgcactc tccgaagtta caaatctgtc cccagacatc
4561 atacaggcta attctctctt ctccttctat ggtgatgatg aaattgttag tacagacata
4621 aaattagatc cagagaagtt gacagcaaag cttaaggagt acgggttgaa accaacccgc
4681 cctgataaaa ctgaagggcc tcttgttatt tctgaagact tagatggttt gactttcctg
4741 cggagaactg tgacccgcga cccagctggt tggtttggaa aattggagca gagctcaata
4801 ctcaggcaaa tgtactggac taggggcccc aaccatgaag atccatctga atcaatgatt
4861 ccacactctc aaagacccat acaattgatg tccttactgg gagaggccgc actccacggc
4921 ccaacattct acagtaaaat cagcaaatta gtcattgcag agctaaaaga aggtggtatg
4981 gatttttacg tgcccaggca agagccaatg ttcagatgga tgagattctc agatctgagc
5041 acgtgggagg gcgatcgcaa tctggctccc agttttgtga atgaagatgg cgtctaacga
5101 cgccaaccca tctgatgggt ccgcagccaa cctcgtccca gaggtcaaca atgaggttat
5161 ggctttggag cccgttgtcg gtgccgctat tgcggcgcct gtagcgggcc aacaaaatgt
5221 aattgacccc tggattagaa ataattttgt acaagcccct ggtggagagt tcacagtgtc
5281 ccctagaaac gctccaggtg aaatactatg gagcgcgccc ttaggccctg atctgaatcc
5341 ctacctatct catttggcca gaatgtataa tggttatgca ggtggttttg aagtgcaggt
5401 gatcctcgcg gggaacgcgt tcaccgccgg aaaaattata tttgcagcag tcccaccaaa
5461 ttttccaact gaaggcttga gtcccagcca ggttactatg ttcccccata taatagtgga
5521 tgttaggcaa ttggaacctg tgttgatccc cttacctgat gttaggaata acttctatca
5581 ttataatcag tcaaatgatt ctaccattaa attgatagca atgttgtata caccacttag
5641 ggctaataat gctggggaag atgtcttcac agtctcttgt cgagttctca cgaggccatc
5701 ccctgatttt gattttatat tcttggtgcc acctacagtt gagtcaagaa ctaaaccatt
5761 tactgtccca atcttaactg ttgaagaaat gaccaattca agattcccca ttcctttgga
5821 aaaattgttt acgggtccca gcagtgcctt tgttgttcaa ccacaaaatg gcagatgcac
5881 gactgatggc gtgctcttag gcaccaccca actgtcccct gtcaacatct gcaccttcag
5941 aggggatgtc acccacatcg caggttctcg taattataca atgaatttgg cttctctaaa
6001 ttggaacaat tatgacccaa cagaagaaat tccagccccc ctaggaactc cagatttcgt
6061 gggaaagatc caaggtgtgc tcactcaaac cacaaaggga gatggctcga cccgcggcca
6121 taaagctaca gtttacactg ggagtgcccc cttcactcca aagctgggca gtgttcaatt
6181 cggtactgat acagaaaatg attttgaaac ccaccaaaac acaaaattca ccccagtcgg
6241 tgtcatccag gatggtggca ccacccaccg aaatgaaccc caacaatggg tgctcccaag
6301 ttattcaggt agaaatgtcc ctaatgtaca cctagccccc gctgtagccc ccacttttcc
6361 aggtgaacaa cttcttttct ttaggtccac tatgcccgga tgcagcgggt atcccaacat
6421 ggatttggat tgcctgctcc cccaggagtg ggtgcagcac ttttaccaag aggcagctcc
6481 agcacaatct gatgtggctc tattgagatt tgtgaatcca gacacgggta gggttctttt
6541 tgagtgcaaa cttcacaaat caggctatgt cacagtggct cacaccggcc agcatgattt
6601 ggtcatcccc cccaatggct attttaggtt tgattcctgg gttaatcagt tctacacact
6661 tgcccccatg ggaaatggaa cggggcgtag acgtgcttta taatggctgg agctttcttt
6721 gctggattgg catccgatgt cctcagctct gggcttggtt ccctaatcaa tgctggggct
6781 ggggctatca accaaaagat tgattttgaa aataatagaa aattgcagca agcttccttc
6841 cagtttagca gtaatctaca acaggcttcc tttcaacacg ataaagagat gctccaagca
6901 caaattgagg ccaccaaaaa gttgcaacag gaaatgatga aagtcaaaca ggcaatgctc
6961 ttagaaggtg gattctctga aacagatgca gcccgtgggg caatcaacgc ccctatgaca
7021 aaggctttgg actggagcgg aacaaggtac tgggcccctg atgctaggat tacaacatat
7081 aatgcaggcc gtttctccac ccctcaacct tcgggggaac tgccaggaag aatcaatccc
7141 aggaccccta cccccgctcg gggctccccc agcacatttt ctaatgcttc tactgcttcc
7201 tctatatatt caaatcaaac tgtttcaacg agacttggtt ctacagctgg ttctggcacc
7261 agtgtctcga gtctcccgtc aactgcaagg actaggagtt gggttgagga tcaaaacaga
7321 aatttgtcac ctttcatgag gggggctcac aacatatcgt ttgtcacccc accatctagc
7381 agatcctcta gccaaggcac agtctcaacc gtgcctaaag aagttttgga ctcctggact
7441 ggcgctttca acacgcgcag gcagcctctc ttcgctcaca ttcgtaggcg aggggagtca
7501 cgggtgtaa
//