Typing tool
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Typing tool
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Complete norovirus genomes
| AB933698 | GII.4 Den Haag | |
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| GII.P4 Den Haag |
ORF1: 1..5097
ORF2: 5081..6703
ORF3: 6703..7509
LOCUS AB933698 7509 bp RNA linear VRL 02-SEP-2015
DEFINITION Norovirus Hu/GII.4/Hiroshimacity2/2011/JP genomic RNA, complete
genome.
ACCESSION AB933698
VERSION AB933698.1
KEYWORDS .
SOURCE Norovirus Hu/GII.4/Hiroshimacity2/2011/JP
ORGANISM Norovirus Hu/GII.4/Hiroshimacity2/2011/JP
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1
AUTHORS Sato,H., Yokoyama,M. and Motomura,K.
TITLE Identification of strong evolutionary constraints on viral capsid
protein during divergent evolution of a norovirus pandemic lineage
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7509)
AUTHORS Sato,H., Nakamura,H. and Motomura,K.
TITLE Direct Submission
JOURNAL Submitted (09-MAY-2014) Contact:Kazushi Motomura National Institute
of Infectious Diseases, Pathogen Genomics Center; Gakuen 4-7-1,
Musashi-Murayama, Tokyo 208-0011, Japan
FEATURES Location/Qualifiers
source 1..7509
/organism="Norovirus Hu/GII.4/Hiroshimacity2/2011/JP"
/mol_type="genomic RNA"
/strain="Hu/GII.4/Hiroshimacity2/2011/JP"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:1498692"
/geo_loc_name="Japan:Hiroshimacity"
/collection_date="2011"
CDS 1..5097
/note="contains N-terminal, NTPase, 3A, VPg, 3Cpro and
3Dpol"
/codon_start=1
/product="polyprotein"
/protein_id="BAS30154.1"
/translation="MKKASNDASAAAVANSNNDTAKSSSDKMFSSMAVTFKRALGARP
KQPPPREIPQRPPRPPTPELVKKIPPPPPNGEDETVCSYSAKDGVSGLPELSTVRQPE
ETNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LAKVELTPLSLFWRPVYTPQYLISPDTLKKLHGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGK
LRPLNIINILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDFELQGPED
LVVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAADRSLPPRAKEELSRTSRPVVLMISGRPGIGKTHLAREV
AKRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALPLQELDDTC
PLTLNCDRIENKGKVFDSDVLIITTNLANPAPLDYVNLEARSRRIDFLVYAETPEVEK
AKHDFPGRPDMWKNAFSSDFSHIRLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVKTM
PELKQALKNTSIKKCQIVYSGCTYTLESDGKGNVKVDRVQSTSVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIIKRVNIQDLWSKPQVENTEEATNKDGC
PKPKDNEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVAGMILEEGAPEG
TVVTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGGEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPSESMIPHSQRPIQLMSLLGEAALHGPTFYSKVSKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGV"
CDS 5081..6703
/codon_start=1
/product="VP1"
/protein_id="BAS30155.1"
/translation="MKMASNDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGEDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMTNSRFPIPLEKLFTGPSGAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFKGDVTHIAGSRNYTMNLASLNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTKGDGSTRGHKATVYTGSAPFTPKLGSVQFSTDTENDFETHQNTKFTPVGVIQDG
GTTHQNEPQQWVLPSYSGRDVPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMNLD
CLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6703..7509
/codon_start=1
/product="VP2"
/protein_id="BAS30156.1"
/translation="MAGAFFAGLASDVLSSGLGSLINAGAGAINQKVDFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATRKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGVLPGRTNPRTPTPARGSPSTSS
NASTATSIYSNQTVSTRLGSTAGSGTNVSSLPSTARTRSWVEGQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRRRGESRV"
ORIGIN
1 atgaagaagg cgtctaacga cgcttccgct gccgctgttg ctaacagcaa caacgacacc
61 gcaaaatctt caagtgacaa aatgttttct agcatggctg tcactttcaa acgagccctc
121 ggggcgcggc ctaaacagcc ccccccgagg gaaataccac aaagaccccc acgaccacct
181 actccagaac tggtcaaaaa gatccctccc cccccgccca acggagagga tgaaacagta
241 tgttcttata gtgctaaaga tggtgtttcc ggcttacctg agctctccac tgtcaggcaa
301 ccggaagaaa ccaatacggc tttcagtgtc cctccactca atcagaggga gaatagggat
361 gctaaggaac cactgactgg aacgattctg gaaatgtggg atggagaaat ctaccattat
421 ggcctatatg ttgagcgagg tcttgtgctg ggcgtgcaca aaccaccagc tgccattagc
481 ctcgcaaagg tcgaactaac accactctcc ttgttctgga gacctgtgta cactcctcag
541 tacctcatct ctccagacac tctcaagaaa ttgcacggag aaacattccc ctacacagcc
601 ttcgacaaca actgctatgc cttctgttgc tgggtcctgg atctaaacga ctcgtggctg
661 agtaggagaa tgatccaaag aacaactggc ttcttcagac cctaccaaga ttggaatagg
721 aaacccctcc ccactatgga tgattccaaa ttaaagaagg tagctaacat attcctgtgc
781 accctgtctt cgctattcac caggcccata aaagacataa tagggaagtt aaggcctctc
841 aacatcatca acatcctggc ttcatgtgat tggactttcg caggcatagt ggagtccttg
901 atactcttgg cagagctctt tggagtcttc tggacacccc cagatgtgtc tgcgatgatt
961 gcccccttac tcggggattt cgagttacaa ggacctgagg atcttgtagt ggagctcgtc
1021 cctgtagtaa tggggggaat tggtttggtg ctaggattca ccaaagagaa gattggaaaa
1081 atgttgtcat ctgctgcatc taccttaaga gcttgtaaag atcttggtgc gtatgggcta
1141 gagatcctaa agttagtcat gaagtggttc ttcccgaaga aagaggaagc aaatgaactg
1201 gccatggtga gatccatcga ggatgcagtg ctagatcttg aggcaattga aaacaaccat
1261 atgaccacct tgctcaaaga caaagacagc ctggcaacct atatgagaac ccttgacctc
1321 gaggaagaga aagccagaaa actttcaacc aagtctgctt cacctgacat cgtgggcaca
1381 atcaacgccc ttctggcgag aatcgccgct gatcgctccc tgcctccccg agcgaaggag
1441 gagctttctc gcacgtctag acctgtagtc ttgatgatat caggcagacc aggaataggg
1501 aagacccacc ttgctaggga agtggctaag agaatcgcag cctccctcac aggagaccag
1561 cgtgtaggcc tcatcccacg caatggcgtc gatcactggg atgcgtacaa gggggagagg
1621 gtcgtcctat gggacgacta tggaatgagc aatcccatcc acgacgccct cccgctgcaa
1681 gaactcgatg acacttgccc cctcactcta aactgtgaca ggattgagaa caaaggaaag
1741 gtctttgaca gcgatgtcct cattatcact actaacctgg ccaaccctgc accactggac
1801 tatgtcaact tggaagctcg ctcgaggcgc attgatttcc tcgtgtatgc agaaaccccc
1861 gaggtcgaaa aggcgaagca tgacttcccg gggcgacctg acatgtggaa aaacgctttt
1921 agttctgatt tctcacacat aagattggca ctggctccac aaggtggctt tgataagaac
1981 gggaacaccc cacatgggaa gggcgtcatg aagactctca ccactggctc cctcattgcc
2041 cgggcatcag ggctgctcca tgagagattg gatgagtttg aattacaggg cccagctctt
2101 accaccttca actttgaccg caacaaagtg cttgccttca ggcagcttgc tgctgaaaat
2161 aaatacgggt tgatggacac aatgaaagtt gggaggcagc tcaaggatgt caaaaccatg
2221 ccagaactta aacaagcact caagaacacc tcaatcaaga agtgccagat tgtgtatagt
2281 ggttgcacct acacacttga gtctgatggc aagggcaatg tgaaagttga cagagttcag
2341 agcacctccg ttcagaccaa caatgagctg gctggcgccc tgcaccacct aaggtgcgcc
2401 agaatcaggt actatgtcaa gtgtgttcag gaggccctgt attctatcat ccagattgct
2461 ggggctgcat ttgtcaccac gcgcatcatc aagcgtgtga acattcaaga cttatggtcc
2521 aagccacaag tggaaaacac agaggaggcc accaacaagg acgggtgccc aaaacccaaa
2581 gataatgagg agttcgtcat ttcatctgac gacattaaaa ctgagggcaa gaaagggaag
2641 aacaagactg gccgtggcaa gaagcacaca gccttctcaa gtaaaggtct cagtgatgaa
2701 gagtatgatg agtacaagag aattagagag gaaaggaatg gtaagtactc tatagaagag
2761 taccttcagg acagggacag atactatgag gaggtggcca ttgccagggc gaccgaggaa
2821 gacttctgtg aagaggagga ggccaagatc cggcaaagga tcttcagacc aacaaggaaa
2881 caacgcaagg aagaaagagc ttccctcggt ttagtcacag gttctgaaat taggaaaagg
2941 aacccagacg acttcaagcc taaggggaaa ctatgggctg atgatgacag aagtgtggac
3001 tacaatgaaa aactcagttt tgaggccccg ccaagcatct ggtcaaggat agtcaacttt
3061 ggctcaggtt ggggcttctg ggtctccccc agcctgttta taacatcaac ccacgtcata
3121 ccccagggcg caaaggagtt ctttggagtc cccatcaaac aaattcaggt acacaagtca
3181 ggcgaattct gtcgcttgag gttcccaaaa ccaatcagga ctgatgtggc tggcatgatc
3241 ttggaagaag gtgcgcccga aggcaccgtg gtcacactac tcatcaaaag gtctactgga
3301 gaacttatgc ccctagcagc tagaatgggg acccatgcaa ccatgaagat tcaagggcgc
3361 actgttggag gtcagatggg catgctccta acaggatcca acgccaaaag catggatcta
3421 ggcaccacac caggtgattg cggctgtccc tacatctata agagaggaaa tgactatgta
3481 gtcattggag tccacacggc tgccgctcgt gggggaaaca ctgtcatatg tgccacccaa
3541 gggggtgagg gggaagctac acttgaaggt ggtgacagta agggaacata ctgtggcgca
3601 ccaatcctag gcccagggag tgccccaaaa cttagcacca aaaccaaatt ctggagatca
3661 tccacagcac cactcccacc cggcacctat gaaccagcct accttggtgg caaggacccc
3721 agagtcaagg gtggcccctc gttgcagcaa gttatgaggg accagctgaa accatttaca
3781 gagcctaggg gcaagccacc aaagccaagt gtgttagaag ctgccaagaa aaccatcatc
3841 aatgtccttg aacaaacaat tgacccacct gagaagtggt cgttcgcaca agcttgcgcg
3901 tcccttgaca agaccacttc tagcggccat ccgcaccaca tgcggaaaaa cgactgctgg
3961 aacggggaat ctttcacagg caagctggca gaccaggctt ctaaggccaa cctgatgttt
4021 gaagaaggga agaacatgac cccagtctac acaggtgcac ttaaggatga attagttaaa
4081 actgacaaaa tttatggtaa gatcaagaag aggcttctct ggggctcgga tttggcaacc
4141 atgatccggt gtgctcgagc attcggaggc ctaatggatg aactcaaagc acactgtgtc
4201 acactcccta tcagagttgg tatgaatatg aatgaggatg gccccatcat cttcgagaag
4261 cattccaggt acagatacca ctatgatgct gattactctc ggtgggattc aacacaacag
4321 agagccgtgc tggcagctgc tctagaaatc atggttaaat tctcctcaga accacatttg
4381 gctcaggtag tagcagaaga ccttctttct cctagcgtgg tggacgtggg tgacttcaca
4441 atatcaatca acgagggtct cccctctggg gtgccctgca cctcccaatg gaactccatc
4501 gcccactggc tcctcactct ctgtgcactc tccgaagtta caaatttgtc cccagacatc
4561 atacaggcta attctctctt ctccttctat ggtgatgatg aaattgttag tacagacata
4621 aaattagacc cagagaagtt gacagcaaag cttaaggaat acgggttgaa accaacccgc
4681 cctgataaaa ctgaaggacc tcttgttatt tctgaagact tagatggctt gaccttcctg
4741 cggagaactg tgacccgcga cccagctggt tggtttggaa aactggagca gagctcaata
4801 ctcaggcaaa tgtactggac taggggcccc aaccatgaag atccatctga atcaatgatt
4861 ccacactctc aaagacccat acaattgatg tccttactgg gagaggccgc actccacggc
4921 ccaacattct acagtaaggt cagcaaatta gtcattgcag agttaaaaga aggtggtatg
4981 gatttttacg tgcccaggca agagccaatg ttcagatgga tgagattctc agatctgagc
5041 acgtgggaag gcgatcgcaa tctggctccc agttttgtga atgaagatgg cgtctaacga
5101 cgccaaccca tctgatgggt ccgcagccaa cctcgtccca gaggtcaaca atgaggttat
5161 ggctttggag cccgttgtcg gtgccgctat tgcggcgcct gtagcgggcc aacaaaatgt
5221 aattgacccc tggattagaa ataattttgt acaagcccct ggtggagagt tcacagtatc
5281 ccctagaaac gctccaggtg aaatactatg gagcgcgccc ttaggccctg atttgaaccc
5341 ctacctatct catttggcca gaatgtataa tggttatgca ggtggttttg aagtgcaggt
5401 gatcctcgcg gggaacgcgt tcaccgccgg aaaaattata tttgcagcag tcccaccaaa
5461 ttttccaact gaaggcttga gtcccagcca ggtcactatg ttcccccata taatagtgga
5521 tgttaggcaa ttggaacctg tgttgatccc cttacctgat gttaggaata atttctatca
5581 ttataatcag tcaaatgatt ctactattaa attgatagca atgctgtata caccacttag
5641 ggctaataat gctggggaag atgtcttcac agtctcttgt cgagtcctca cgaggccatc
5701 ccctgatttt gattttatat ttttggtgcc acctacagtt gagtcaagaa ctaaaccatt
5761 tactgtccca atcttaactg ttgaagaaat gaccaattca agattcccca ttcctttgga
5821 gaaattgttc acgggtccca gcggtgcctt tgttgttcaa ccgcaaaatg gcagatgcac
5881 gactgatggc gtgctcctag gcaccaccca actgtctcct gtcaacattt gcaccttcaa
5941 aggggatgtc acccacattg caggttctcg taattacaca atgaatttgg cttctctaaa
6001 ttggaacaat tatgacccaa cagaagaaat tccagcccct ctaggaactc cagatttcgt
6061 gggaaagatc caaggtgtgc tcactcaaac cacaaaggga gatggttcga cccgtggcca
6121 caaagctaca gtctacactg ggagtgctcc ctttactcca aagctgggca gtgttcaatt
6181 cagtactgat acagaaaatg attttgaaac tcaccaaaac acaaaattca ccccagtcgg
6241 tgtcatccag gatggtggca ccacccatca aaatgaaccc caacaatggg tgctcccaag
6301 ttattcaggt agagatgtcc ctaatgtaca cctagcccct gctgtggccc ccactttccc
6361 gggtgaacaa cttcttttct ttaggtccac catgcccgga tgcagcgggt atcccaacat
6421 gaatttggac tgcctactcc cccaggagtg ggtgcagcac ttctaccaag aggcagctcc
6481 agcacaatct gatgtggctt tattgagatt tgtgaatcca gacacgggta gggtcctgtt
6541 tgagtgcaaa cttcataaat caggctatgt cacagtggct cacaccggcc agcatgatct
6601 ggtcatcccc cccaatggtt attttaggtt tgattcctgg gttaatcaat tctacacact
6661 cgcccccatg ggaaatggaa cggggcgtag acgtgcttta taatggctgg agctttcttt
6721 gctgggttgg catctgatgt ccttagctct ggacttggtt ccctaatcaa tgctggggct
6781 ggggctatca accaaaaggt tgattttgag aataacagaa aattgcagca agcttccttc
6841 cagtttagca gtaatctaca acaggcttcc tttcaacatg ataaagaaat gctccaagca
6901 caaattgagg ccactagaaa gttgcaacag gaaatgatga aagtcaaaca ggcaatgctc
6961 ttagaaggtg gattctctga aacagatgca gcccgtgggg caatcaacgc ccctatgaca
7021 aaggctttgg actggagcgg aacaaggtac tgggcccctg atgctaggac tacaacatac
7081 aacgcaggcc gtttttccac ccctcaacct tcgggggtac tgccaggaag aaccaatccc
7141 aggactccta cccccgcccg gggctccccc agcacatctt ctaatgcttc tactgctact
7201 tctatatatt caaatcaaac tgtttcaacg agacttggtt ctacagctgg ttctggcacc
7261 aatgtctcga gtctcccgtc aactgcaagg actaggagtt gggttgaggg tcaaaacaga
7321 aatttgtcac ctttcatgag gggggctcac aatatatcgt ttgtcacccc accatctagc
7381 agatcctcta gccaaggcac agtctcaacc gtgcctaaag aagttttgga ctcctggact
7441 ggcgctttca acacgcgcag gcagcctctc ttcgctcaca tacgtaggcg aggggagtca
7501 cgggtgtaa
//